Compare all timetables for the bus from Chicago to San Diego
Here is a selection of the cheapest bus trips from the schedule from Chicago to San Diego from various bus operators like Greyhound US or FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 69h 10m | 10:00 PM | Chicago | Union Station | 5:10 PM | San Diego | San Ysidro Transit Center | Economy | $294 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/5/2025 10:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/8/2025 5:10:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 69h 10m
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| Greyhound US | 58h 20m | 10:00 AM | Chicago | Union Station | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $299 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/5/2025 10:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/7/2025 6:20:00 PM. 50 Economy ticket for $299 per person are available. Travel duration is 58h 20m
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| Greyhound US | 52h 39m | 12:01 PM | Chicago | Downtown Bus Station | 2:40 PM | San Diego | San Ysidro Transit Center | Economy | $309 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 12:01:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/7/2025 2:40:00 PM. 50 Economy ticket for $309 per person are available. Travel duration is 52h 39m
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| FlixBus | 51h 50m | 4:30 PM | Chicago | Downtown Bus Station | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $313 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 4:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/7/2025 6:20:00 PM. 50 Economy ticket for $313 per person are available. Travel duration is 51h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 57h 45m | 10:00 AM | Chicago | Union Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $208 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/6/2025 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 5:45:00 PM. 50 Economy ticket for $208 per person are available. Travel duration is 57h 45m
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| Greyhound US | 62h 15m | 10:00 AM | Chicago | Union Station | 10:15 PM | San Diego | Seaport Village | Economy | $209 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/6/2025 10:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/8/2025 10:15:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 62h 15m
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| Greyhound US | 51h 39m | 12:01 PM | Chicago | Downtown Bus Station | 1:40 PM | San Diego | La Jolla Village | Economy | $211 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 12:01:00 PM to La Jolla Village, San Diego (USA) arriving at 12/8/2025 1:40:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 51h 39m
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| FlixBus | 55h 45m | 4:30 PM | Chicago | Downtown Bus Station | 10:15 PM | San Diego | Seaport Village | Economy | $256 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 4:30:00 PM to Seaport Village, San Diego (USA) arriving at 12/8/2025 10:15:00 PM. 50 Economy ticket for $256 per person are available. Travel duration is 55h 45m
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| FlixBus | 51h 5m | 4:30 PM | Chicago | Downtown Bus Station | 5:35 PM | San Diego | La Jolla Village | Economy | $257 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 4:30:00 PM to La Jolla Village, San Diego (USA) arriving at 12/8/2025 5:35:00 PM. 50 Economy ticket for $257 per person are available. Travel duration is 51h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 62h 15m | 10:00 AM | Chicago | Union Station | 10:15 PM | San Diego | Seaport Village | Economy | $286 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/8/2025 10:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/10/2025 10:15:00 PM. 50 Economy ticket for $286 per person are available. Travel duration is 62h 15m
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| Greyhound US | 63h 50m | 10:00 AM | Chicago | Union Station | 11:50 PM | San Diego | Old Town Transit Center | Economy | $286 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/8/2025 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/10/2025 11:50:00 PM. 50 Economy ticket for $286 per person are available. Travel duration is 63h 50m
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| Greyhound US | 58h 10m | 10:00 AM | Chicago | Union Station | 6:10 PM | San Diego | Old Town Transit Center | Economy | $293 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/8/2025 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/10/2025 6:10:00 PM. 50 Economy ticket for $293 per person are available. Travel duration is 58h 10m
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| FlixBus | 55h 45m | 4:30 PM | Chicago | Downtown Bus Station | 10:15 PM | San Diego | Seaport Village | Economy | $294 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 4:30:00 PM to Seaport Village, San Diego (USA) arriving at 12/10/2025 10:15:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 55h 45m
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| FlixBus | 51h 40m | 4:30 PM | Chicago | Downtown Bus Station | 6:10 PM | San Diego | Old Town Transit Center | Economy | $295 |
A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 4:30:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/10/2025 6:10:00 PM. 50 Economy ticket for $295 per person are available. Travel duration is 51h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 52h 9m | 12:01 PM | Chicago | Downtown Bus Station | 2:10 PM | San Diego | Old Town Transit Center | Economy | $198 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/10/2025 12:01:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/12/2025 2:10:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 52h 9m
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| Greyhound US | 51h 39m | 12:01 PM | Chicago | Downtown Bus Station | 1:40 PM | San Diego | La Jolla Village | Economy | $199 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/10/2025 12:01:00 PM to La Jolla Village, San Diego (USA) arriving at 12/12/2025 1:40:00 PM. 50 Economy ticket for $199 per person are available. Travel duration is 51h 39m
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| Greyhound US | 74h 15m | 10:00 PM | Chicago | Union Station | 10:15 PM | San Diego | Seaport Village | Economy | $203 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/10/2025 10:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/13/2025 10:15:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 74h 15m
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| Greyhound US | 62h 15m | 10:00 AM | Chicago | Union Station | 10:15 PM | San Diego | Seaport Village | Economy | $209 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/10/2025 10:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/12/2025 10:15:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 62h 15m
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| Greyhound US | 57h 45m | 10:00 AM | Chicago | Union Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $209 |
A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/10/2025 10:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/12/2025 5:45:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 57h 45m
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Best Price Offer: The price for the cheapest bus from Chicago to San Diego is $198 on 12/10/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Chicago and San Diego
Saturday
is the busiest day, with more than 14 daily buses from Chicago to San Diego. Friday has instead the fewest connections, with only 5 daily coaches between Chicago and San Diego.
The busiest time of the day is the Afternoon, with 20 buses from Chicago to San Diego, while Evening sees the fewest connections between Chicago and San Diego, with 4 offers.
Facts about the bus from Chicago to San Diego
Compare all providers like Greyhound US and FlixBus that travel 9 times every day by bus from Chicago to San Diego in one click! Book your bus ticket from Chicago to San Diego starting from $198!
| Cheapest Bus | $198 |
| Fastest Bus | 49h 5m |
| Earliest Bus | 10:00 AM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 9 Ø |
| Distance | 1,730.9 miles |
| Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from Chicago to San Diego
Every day, 9 buses from 2 bus companies leave Chicago for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
$294
Saturday
12/06
$287
Sunday
12/07
Monday
12/08
$286
Tuesday
12/09
Wednesday
12/10
$198
Thursday
12/11
Friday
12/12
Saturday
12/13
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
The cheapest time to travel from Chicago to San Diego
With a price starting from $198, Wednesday is the cheapest day for a bus from Chicago to San Diego. Friday instead is the most expensive day with prices starting from $294.
Afternoon
is the cheapest day time for bus tickets from Chicago to San Diego, with $198. Morning is the most expensive time of the day with prices starting from $208.
How to save money travelling from Chicago to San Diego
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Chicago to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to San Diego are also emptier.Beloved bus companies from Chicago to San Diego
These are the most booked bus companies between Chicago to San Diego from our users.
Greyhound US from Chicago to San Diego
Here you will find the key facts about the Greyhound US bus route Chicago to San Diego:
| Cheapest Price | $198 |
| Fastest Bus | 49h 39m |
| Earliest Bus | 10:00 AM |
| Last Bus | 10:00 PM |
| Daily Connections | 7 Ø |
| Found on | 12/1/2025 |
All bus stations and stops in Chicago and San Diego
In the map below, you can see where to find all bus stations in Chicago and San Diego.
Compare the bus with other modes of transport
The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Chicago to San Diego? Compare all modes of transports from
Chicago to San Diego.
Service and Comfort on the bus from Chicago to San Diego
Want to know which seat classes are available on the buses from Chicago to San Diego? Or which bus companies serve the route Chicago to San Diego? Below you will find answers to your questions.
FAQs about the Chicago to San Diego bus
How much does a Chicago San Diego bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $198 and takes 50h 9m to reach San Diego. Compare offers to save money!
How much could I save by comparing buses from Chicago to San Diego?
This route is offered by 2 companies with a range of ticket prices between $198 and $334. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.
On average, how many connections are available from Chicago to San Diego each day?
Every day, the Chicago to San Diego bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Chicago to San Diego take?
The fastest bus from Chicago to San Diego is offered by FlixBus and takes 49h 5m. Bus tickets for this connection cost $257. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Chicago to San Diego?
The earliest bus arriving in San Diego from Chicago starts at 10:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Chicago to San Diego?
The latest bus trip departing from Chicago for San Diego starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Chicago San Diego route?
When traveling by bus from Chicago to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Chicago and San Diego?
You can check all the direct connections between Chicago and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.
What can I take with me on the Chicago to San Diego bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Chicago San Diego bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to San Diego on your planned travel date.
Available seat classes which are offered on the bus route Chicago to San Diego
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Chicago and to San Diego
Here’s an overview of the most popular bus routes to Chicago and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Chicago
- Buses to Chicago from Bloomington, IL
- Bus to Chicago from Bloomington, IN
- Buses from Cincinnati to Chicago
- Bus Cleveland to Chicago
- Buses to Chicago from Columbus, OH
- Buses from Dallas to Chicago
- From Frederick, MD to Chicago bus
- Buses Indianapolis to Chicago
- Buses Iowa City, IA - Chicago
- Buses to Chicago from Joplin, MO
- Buses from Kansas City to Chicago
- From Lansing, MI to Chicago bus
- Bus Los Angeles - Chicago
- Louisville, KY to Chicago bus
- Buses from Niagara Falls, ON to Chicago
- Buses Orlando, FL - Chicago
- Bus from Phoenix, AZ to Chicago
- South Bend, IN to Chicago bus
- Buses from Springfield, IL to Chicago
- Bus Springfield, OH - Chicago
- Bus Routes to San Diego
- Bus to San Diego from Bakersfield, CA
- Bus Barstow, CA to San Diego
- Bus Dallas to San Diego
- Buses from El Paso, TX to San Diego
- Buses Ensenada to San Diego
- Buses to San Diego from Fresno, CA
- Bus Glendale, AZ to San Diego
- Bus to San Diego from Indianapolis
- Bus Las Vegas - San Diego
- Buses to San Diego from Los Angeles
- Lubbock, TX to San Diego bus
- Bus from Merced, CA to San Diego
- Bus New York - San Diego
- Buses to San Diego from Palm Springs, CA
- Bus Pasco, WA - San Diego
- Buses to San Diego from San Fernando, CA
- Bus to San Diego from Santa Ana, CA
- Bus to San Diego from Santa Barbara, CA
- From Temecula, CA to San Diego bus
- Buses from Yuma, AZ to San Diego
Popular Airport Shuttles to Chicago and to San Diego
