Compare all timetables for the bus from Louisville, KY to Chicago
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 6h 35m | 2:35 PM | Louisville, KY | Greyhound Bus Station | 8:10 PM | Chicago | Downtown Bus Station | Economy | $46 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/22/2026 2:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/22/2026 8:10:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 6h 35m
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| FlixBus | 5h 20m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 11:50 PM | Chicago | 95th Red Line Station | Economy | $46 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/22/2026 7:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/22/2026 11:50:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 20m
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| FlixBus | 5h 40m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 12:10 AM | Chicago | Downtown Bus Station | Economy | $46 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/22/2026 7:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/23/2026 12:10:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 40m
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| Greyhound US | 6h 5m | 10:10 AM | Louisville, KY | Greyhound Bus Station | 3:15 PM | Chicago | Downtown Bus Station | Economy | $47 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/22/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/22/2026 3:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 6h 5m
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| Greyhound US | 7h 10m | 7:35 AM | Louisville, KY | Greyhound Bus Station | 1:45 PM | Chicago | Union Station | Economy | $49 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/22/2026 7:35:00 AM to Union Station, Chicago (USA) arriving at 6/22/2026 1:45:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 7h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 6h 35m | 2:35 PM | Louisville, KY | Greyhound Bus Station | 8:10 PM | Chicago | Downtown Bus Station | Economy | $42 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/23/2026 2:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/23/2026 8:10:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 6h 35m
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| FlixBus | 5h 20m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 11:50 PM | Chicago | 95th Red Line Station | Economy | $43 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/23/2026 7:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 11:50:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 20m
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| Greyhound US | 6h 10m | 2:50 AM | Louisville, KY | Greyhound Bus Station | 8:00 AM | Chicago | Union Station | Economy | $44 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/23/2026 2:50:00 AM to Union Station, Chicago (USA) arriving at 6/23/2026 8:00:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 6h 10m
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| Greyhound US | 7h 10m | 7:35 AM | Louisville, KY | Greyhound Bus Station | 1:45 PM | Chicago | Union Station | Economy | $44 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/23/2026 7:35:00 AM to Union Station, Chicago (USA) arriving at 6/23/2026 1:45:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 7h 10m
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| FlixBus | 5h 40m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 12:10 AM | Chicago | Downtown Bus Station | Economy | $44 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/23/2026 7:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/24/2026 12:10:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 5h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 20m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 11:50 PM | Chicago | 95th Red Line Station | Economy | $39 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/25/2026 7:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/25/2026 11:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 5h 20m
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| Greyhound US | 6h 10m | 2:50 AM | Louisville, KY | Greyhound Bus Station | 8:00 AM | Chicago | Canal & Van Buren | Economy | $40 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/25/2026 2:50:00 AM to Canal & Van Buren, Chicago (USA) arriving at 6/25/2026 8:00:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 6h 10m
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| Greyhound US | 6h 35m | 2:50 AM | Louisville, KY | Greyhound Bus Station | 8:25 AM | Chicago | Downtown Bus Station | Economy | $40 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/25/2026 2:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/25/2026 8:25:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 6h 35m
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| Greyhound US | 6h 5m | 10:10 AM | Louisville, KY | Greyhound Bus Station | 3:15 PM | Chicago | Downtown Bus Station | Economy | $40 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/25/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/25/2026 3:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 6h 5m
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| FlixBus | 5h 40m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 12:10 AM | Chicago | Downtown Bus Station | Economy | $40 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/25/2026 7:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/26/2026 12:10:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 5h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 6h 0m | 10:15 AM | Louisville, KY | Greyhound Bus Station | 3:15 PM | Chicago | Downtown Bus Station | Economy | $55 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/26/2026 10:15:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/26/2026 3:15:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 6h 0m
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| FlixBus | 7h 20m | 4:45 AM | Louisville, KY | Greyhound Bus Station | 11:05 AM | Chicago | 95th Red Line Station | Economy | $64 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/26/2026 4:45:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 11:05:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 20m
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| FlixBus | 7h 45m | 4:45 AM | Louisville, KY | Greyhound Bus Station | 11:30 AM | Chicago | Downtown Bus Station | Economy | $66 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/26/2026 4:45:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/26/2026 11:30:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 45m
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| Greyhound US | 6h 25m | 2:45 PM | Louisville, KY | Greyhound Bus Station | 8:10 PM | Chicago | Downtown Bus Station | Economy | $68 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/26/2026 2:45:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/26/2026 8:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 6h 25m
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| Greyhound US | 9h 10m | 10:15 AM | Louisville, KY | Greyhound Bus Station | 6:25 PM | Chicago | 95th Red Line Station | Economy | $69 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/26/2026 10:15:00 AM to 95th Red Line Station, Chicago (USA) arriving at 6/26/2026 6:25:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 9h 10m
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Greyhound US6h 40m07:35 AMLouisville, KYGreyhound Bus Station12:35 PMGary, INAdam Benjamin JR Metro Center0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/23/2026 7:35:00 AM to Adam Benjamin JR Metro Center, Gary, IN (USA) arriving at 6/23/2026 12:35:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 6h 0m
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Greyhound US0h 35m012:40 PMGary, INAdam Benjamin JR Metro Center1:15 PMChicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Adam Benjamin JR Metro Center, Gary, IN (USA) at 6/23/2026 12:40:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/23/2026 1:15:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 35m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 6h 35m | 2:35 PM | Louisville, KY | Greyhound Bus Station | 8:10 PM | Chicago | Downtown Bus Station | Economy | $44 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/27/2026 2:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/27/2026 8:10:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 6h 35m
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| Greyhound US | 6h 5m | 10:10 AM | Louisville, KY | Greyhound Bus Station | 3:15 PM | Chicago | Downtown Bus Station | Economy | $45 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/27/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/27/2026 3:15:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 6h 5m
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| Greyhound US | 6h 10m | 2:50 AM | Louisville, KY | Greyhound Bus Station | 8:00 AM | Chicago | Union Station | Economy | $47 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/27/2026 2:50:00 AM to Union Station, Chicago (USA) arriving at 6/27/2026 8:00:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 6h 10m
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| FlixBus | 5h 40m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 12:10 AM | Chicago | Downtown Bus Station | Economy | $47 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/27/2026 7:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/28/2026 12:10:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 5h 40m
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| FlixBus | 7h 40m | 4:50 AM | Louisville, KY | Greyhound Bus Station | 11:30 AM | Chicago | Downtown Bus Station | Economy | $50 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/27/2026 4:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/27/2026 11:30:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 7h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 6h 5m | 10:10 AM | Louisville, KY | Greyhound Bus Station | 3:15 PM | Chicago | Downtown Bus Station | Economy | $43 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/28/2026 10:10:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/28/2026 3:15:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 5m
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| Greyhound US | 6h 35m | 2:35 PM | Louisville, KY | Greyhound Bus Station | 8:10 PM | Chicago | Downtown Bus Station | Economy | $43 |
A Bus from Greyhound US goes from Greyhound Bus Station, Louisville, KY (USA) at 6/28/2026 2:35:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/28/2026 8:10:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 6h 35m
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| FlixBus | 5h 40m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 12:10 AM | Chicago | Downtown Bus Station | Economy | $43 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/28/2026 7:30:00 PM to Downtown Bus Station, Chicago (USA) arriving at 6/29/2026 12:10:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 5h 40m
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| FlixBus | 5h 20m | 7:30 PM | Louisville, KY | Greyhound Bus Station | 11:50 PM | Chicago | 95th Red Line Station | Economy | $45 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/28/2026 7:30:00 PM to 95th Red Line Station, Chicago (USA) arriving at 6/28/2026 11:50:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 5h 20m
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| FlixBus | 7h 40m | 4:50 AM | Louisville, KY | Greyhound Bus Station | 11:30 AM | Chicago | Downtown Bus Station | Economy | $46 |
A Bus from FlixBus goes from Greyhound Bus Station, Louisville, KY (USA) at 6/28/2026 4:50:00 AM to Downtown Bus Station, Chicago (USA) arriving at 6/28/2026 11:30:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 7h 40m
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Best Price Offer: The price for the cheapest bus from Louisville, KY to Chicago is $38 on 7/16/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Louisville, KY and Chicago
Facts about the bus from Louisville, KY to Chicago
Compare all providers like Greyhound US and FlixBus that travel 17 times every day by bus from Louisville, KY to Chicago in one click! Book your bus ticket from Louisville, KY to Chicago starting from $38!
| Cheapest Bus | $38 |
| Fastest Bus | 4h 20m |
| Earliest Bus | 2:50 AM |
| Latest Bus | 7:30 PM |
| Daily Bus Routes | 17 Ø |
| Distance | 269.3 miles |
| Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from Louisville, KY to Chicago
Every day, 17 buses from 2 bus companies leave Louisville, KY for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.
The cheapest time to travel from Louisville, KY to Chicago
How to save money travelling from Louisville, KY to Chicago
Book the ticket from Louisville, KY to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Louisville, KY to Chicago, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Louisville, KY to Chicago are also emptier.Beloved bus companies from Louisville, KY to Chicago
Greyhound US from Louisville, KY to Chicago
Here you will find the key facts about the Greyhound US bus route Louisville, KY to Chicago:
| Cheapest Price | $40 |
| Fastest Bus | 5h 0m |
| Earliest Bus | 2:50 AM |
| Last Bus | 2:35 PM |
| Daily Connections | 12 Ø |
| Found on | 6/21/2026 |
FlixBus from Louisville, KY to Chicago
Here you will find the key facts about the FlixBus bus route Louisville, KY to Chicago:
| Cheapest Price | $39 |
| Fastest Bus | 4h 20m |
| Earliest Bus | 4:50 AM |
| Last Bus | 7:30 PM |
| Daily Connections | 4 Ø |
| Found on | 6/21/2026 |
All bus stations and stops in Louisville, KY and Chicago
In the map below, you can see where to find all bus stations in Louisville, KY and Chicago.
Service and Comfort on the bus from Louisville, KY to Chicago
FAQs about the Louisville, KY to Chicago bus
How much does a Louisville, KY Chicago bus trip cost?
How much could I save by comparing buses from Louisville, KY to Chicago?
On average, how many connections are available from Louisville, KY to Chicago each day?
How long does a bus journey from Louisville, KY to Chicago take?
What time is the first bus from Louisville, KY to Chicago?
What time is the last bus from Louisville, KY to Chicago?
Which bus companies operate the Louisville, KY Chicago route?
Is there a direct bus between Louisville, KY and Chicago?
What can I take with me on the Louisville, KY to Chicago bus route?
What equipment is available for the Louisville, KY Chicago bus route?
How does CheckMyBus find the best bus deals from Louisville, KY to Chicago?
How does CheckMyBus technology work for trips from Louisville, KY to Chicago?
Available seat classes which are offered on the bus route Louisville, KY to Chicago
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Louisville, KY and to Chicago
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