How to get from Chicago to San Diego

Compare Flights and Buses with one click and find the best one for you
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

What is the best way to travel from Chicago to San Diego?

Looking for a trip? Compare all the available Flights and Buses for the journey to San Diego from Chicago. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Flight is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
50h 55m
$129
$156
26
Flight
4h 27m
$89
$300
107

What is the cheapest way to reach San Diego from Chicago?

You can get to San Diego with just $89 by taking a Flight from Frontier Airlines, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Tuesday
from $119
Wednesday
from $112
Thursday
from $131
Friday
from $129
Saturday
from $89
Sunday
from $102
Monday
from $99

    Cheapest Flights Tuesday

  • Frontier Airlines
    11h 10m
    0
    2:41 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    11:51 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $119
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $120
  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $131
  • JetBlue Airways
    10h 28m
    0
    11:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    7:29 PM
    San Diego Airport
    San Diego Airport
    0
    JetBlue Airways
    Economy
    from $184
  • American Airlines
    10h 54m
    0
    11:30 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:24 PM
    San Diego Airport
    San Diego Airport
    0
    American Airlines
    Economy
    from $363
  • United Airlines
    8h 4m
    0
    6:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:04 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $439

    Cheapest Flights Wednesday

  • Frontier Airlines
    11h 10m
    0
    2:41 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    11:51 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $112
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $126
  • Alaska Airlines
    4h 37m
    0
    2:18 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    4:55 PM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $126
  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $131
  • Volaris
    11h 47m
    0
    2:53 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:40 PM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $152
  • Viva Aerobus
    8h 50m
    0
    12:25 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    7:15 PM
    Tijuana Airport
    Tijuana Airport
    0
    Viva Aerobus
    Economy
    from $184
  • Cheapest Buses Wednesday

  • Greyhound US
    54h 0m
    0
    12:25 PM
    Chicago
    Downtown Bus Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $145
  • Greyhound US
    53h 30m
    0
    12:25 PM
    Chicago
    Downtown Bus Station
    3:55 PM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $145
  • Greyhound US
    62h 0m
    0
    10:15 AM
    Chicago
    Union Station
    10:15 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $150
  • FlixBus
    55h 0m
    0
    5:15 PM
    Chicago
    Downtown Bus Station
    10:15 PM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $188
  • FlixBus
    50h 55m
    0
    5:15 PM
    Chicago
    Downtown Bus Station
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $190

    Cheapest Buses Thursday

  • FlixBus
    61h 5m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    11:45 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $131
  • FlixBus
    55h 20m
    0
    11:05 AM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $131
  • FlixBus
    59h 45m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    10:25 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $133
  • Greyhound US
    54h 0m
    0
    12:25 PM
    Chicago
    Downtown Bus Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $147
  • Greyhound US
    54h 50m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $148
  • Cheapest Flights Thursday

  • Frontier Airlines
    8h 21m
    0
    9:20 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    3:41 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $131
  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $134
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $134
  • Volaris
    11h 47m
    0
    2:53 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:40 PM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $138
  • Viva Aerobus
    10h 0m
    0
    12:25 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:25 PM
    Tijuana Airport
    Tijuana Airport
    0
    Viva Aerobus
    Economy
    from $185
  • Sun Country Airlines
    17h 53m
    0
    5:12 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:05 AM
    San Diego Airport
    San Diego Airport
    0
    Sun Country Airlines
    Economy
    from $206

    Cheapest Buses Friday

  • FlixBus
    55h 20m
    0
    11:05 AM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $129
  • Greyhound US
    58h 55m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    10:15 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $138
  • Greyhound US
    54h 25m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $138
  • FlixBus
    59h 25m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    10:05 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $142
  • FlixBus
    59h 45m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    10:25 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $143
  • Cheapest Flights Friday

  • Frontier Airlines
    20h 24m
    0
    2:41 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:05 AM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $131
  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $154
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $154
  • Volaris
    12h 30m
    0
    8:23 PM
    Chicago Midway Airport
    Chicago Midway Airport
    6:53 AM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $234
  • Volaris
    31h 21m
    0
    8:23 PM
    Chicago Midway Airport
    Chicago Midway Airport
    1:44 AM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $234
  • Volaris
    24h 52m
    0
    8:23 PM
    Chicago Midway Airport
    Chicago Midway Airport
    7:15 PM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $244

    Cheapest Flights Saturday

  • Frontier Airlines
    8h 21m
    0
    9:20 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    3:41 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $89
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $110
  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $120
  • Volaris
    15h 38m
    0
    1:40 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    3:18 PM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $168
  • Frontier Airlines
    39h 21m
    0
    8:45 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    10:06 PM
    Tijuana Airport
    Tijuana Airport
    0
    Frontier Airlines
    Economy
    from $205
  • Delta Air Lines
    22h 9m
    0
    6:30 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    2:39 PM
    Tijuana Airport
    Tijuana Airport
    0
    Delta Air Lines
    Economy
    from $263
  • Cheapest Buses Saturday

  • FlixBus
    55h 20m
    0
    11:05 AM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $140
  • FlixBus
    61h 5m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    11:45 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $142
  • FlixBus
    66h 30m
    0
    11:55 PM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $143
  • Greyhound US
    58h 55m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    10:15 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $154
  • Greyhound US
    54h 25m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $155

    Cheapest Flights Sunday

  • American Airlines
    24h 39m
    0
    9:35 PM
    Chicago Midway Airport
    Chicago Midway Airport
    8:14 PM
    San Diego Airport
    San Diego Airport
    0
    American Airlines
    Economy
    from $102
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $109
  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $120
  • Frontier Airlines
    26h 3m
    0
    8:11 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:14 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $141
  • Volaris
    10h 0m
    0
    6:21 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    2:21 PM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $160
  • Volaris
    14h 3m
    0
    6:21 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    6:24 PM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $160

    Cheapest Flights Monday

  • Frontier Airlines
    8h 21m
    0
    9:20 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    3:41 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $99
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $107
  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $120
  • JetBlue Airways
    14h 45m
    0
    8:20 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:05 AM
    San Diego Airport
    San Diego Airport
    0
    JetBlue Airways
    Economy
    from $223
  • Sun Country Airlines
    7h 42m
    0
    10:43 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    4:25 PM
    San Diego Airport
    San Diego Airport
    0
    Sun Country Airlines
    Economy
    from $333
  • Cheapest Buses Monday

  • Greyhound US
    58h 5m
    0
    10:15 AM
    Chicago
    Union Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $179
  • Greyhound US
    69h 10m
    0
    11:10 PM
    Chicago
    Union Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $203
  • Greyhound US
    69h 30m
    0
    10:50 PM
    Chicago
    Downtown Bus Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $203
  • FlixBus
    51h 5m
    0
    5:15 PM
    Chicago
    Downtown Bus Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $215

What are the fastest trips from Chicago to San Diego?

You can get to San Diego from Chicago in just 4h 27m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Tuesday
from 4h 27m
Wednesday
from 4h 27m
Thursday
from 4h 27m
Friday
from 4h 27m
Saturday
from 4h 27m
Sunday
from 4h 27m
Monday
from 4h 27m

    Fastest Flights Tuesday

  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $131
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $120
  • United Airlines
    7h 29m
    0
    12:51 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    6:20 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $441
  • United Airlines
    8h 4m
    0
    6:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:04 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $439
  • United Airlines
    9h 45m
    0
    10:35 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    6:20 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $441
  • JetBlue Airways
    10h 28m
    0
    11:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    7:29 PM
    San Diego Airport
    San Diego Airport
    0
    JetBlue Airways
    Economy
    from $184

    Fastest Flights Wednesday

  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $131
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $126
  • Alaska Airlines
    4h 37m
    0
    2:18 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    4:55 PM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $126
  • United Airlines
    8h 0m
    0
    7:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    1:00 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $573
  • United Airlines
    8h 4m
    0
    6:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:04 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $441
  • United Airlines
    8h 10m
    0
    2:35 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:45 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $441
  • Fastest Buses Wednesday

  • FlixBus
    50h 55m
    0
    5:15 PM
    Chicago
    Downtown Bus Station
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $190
  • Greyhound US
    53h 30m
    0
    12:25 PM
    Chicago
    Downtown Bus Station
    3:55 PM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $145
  • Greyhound US
    54h 0m
    0
    12:25 PM
    Chicago
    Downtown Bus Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $145
  • FlixBus
    55h 0m
    0
    5:15 PM
    Chicago
    Downtown Bus Station
    10:15 PM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $188
  • Greyhound US
    62h 0m
    0
    10:15 AM
    Chicago
    Union Station
    10:15 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $150

    Fastest Flights Thursday

  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $134
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $134
  • United Airlines
    6h 20m
    0
    8:40 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    1:00 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $578
  • United Airlines
    8h 4m
    0
    6:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:04 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $439
  • United Airlines
    8h 10m
    0
    2:35 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:45 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $443
  • United Airlines
    8h 10m
    0
    2:42 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:52 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $578
  • Fastest Buses Thursday

  • Greyhound US
    54h 0m
    0
    12:25 PM
    Chicago
    Downtown Bus Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $147
  • Greyhound US
    54h 50m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $148
  • FlixBus
    55h 20m
    0
    11:05 AM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $131
  • FlixBus
    59h 45m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    10:25 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $133
  • FlixBus
    61h 5m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    11:45 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $131

    Fastest Flights Friday

  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $154
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $154
  • United Airlines
    8h 4m
    0
    6:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:04 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $450
  • United Airlines
    8h 10m
    0
    2:35 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:45 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $450
  • United Airlines
    9h 54m
    0
    12:51 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:45 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $450
  • United Airlines
    10h 0m
    0
    5:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    1:00 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $488
  • Fastest Buses Friday

  • Greyhound US
    54h 25m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $138
  • FlixBus
    55h 20m
    0
    11:05 AM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $129
  • Greyhound US
    58h 55m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    10:15 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $138
  • FlixBus
    59h 25m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    10:05 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $142
  • FlixBus
    59h 45m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    10:25 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $143

    Fastest Flights Saturday

  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $120
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $110
  • United Airlines
    6h 31m
    0
    8:29 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    1:00 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $569
  • United Airlines
    7h 29m
    0
    12:51 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    6:20 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $444
  • United Airlines
    8h 4m
    0
    6:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:04 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $444
  • Frontier Airlines
    8h 21m
    0
    9:20 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    3:41 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $89
  • Fastest Buses Saturday

  • Greyhound US
    54h 25m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $155
  • FlixBus
    55h 20m
    0
    11:05 AM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $140
  • Greyhound US
    58h 55m
    0
    1:20 PM
    Chicago
    95th Red Line Station
    10:15 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $154
  • FlixBus
    61h 5m
    0
    12:40 AM
    Chicago
    95th Red Line Station
    11:45 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $142
  • FlixBus
    66h 30m
    0
    11:55 PM
    Chicago
    95th Red Line Station
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $143

    Fastest Flights Sunday

  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $120
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $109
  • United Airlines
    8h 4m
    0
    6:00 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    12:04 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $450
  • United Airlines
    8h 10m
    0
    2:35 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:45 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $450
  • United Airlines
    9h 54m
    0
    12:51 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:45 PM
    McClellan-Palomar Airport
    McClellan-Palomar Airport
    0
    United Airlines
    Economy
    from $450
  • Volaris
    10h 0m
    0
    6:21 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    2:21 PM
    Tijuana Airport
    Tijuana Airport
    0
    Volaris
    Economy
    from $160

    Fastest Flights Monday

  • United Airlines
    4h 27m
    0
    7:05 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:32 AM
    San Diego Airport
    San Diego Airport
    0
    United Airlines
    Economy
    from $120
  • Alaska Airlines
    4h 31m
    0
    6:01 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    8:32 AM
    San Diego Airport
    San Diego Airport
    0
    Alaska Airlines
    Economy
    from $107
  • Sun Country Airlines
    7h 42m
    0
    10:43 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    4:25 PM
    San Diego Airport
    San Diego Airport
    0
    Sun Country Airlines
    Economy
    from $333
  • Frontier Airlines
    8h 21m
    0
    9:20 AM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    3:41 PM
    San Diego Airport
    San Diego Airport
    0
    Frontier Airlines
    Economy
    from $99
  • JetBlue Airways
    14h 45m
    0
    8:20 PM
    Chicago O'Hare Airport
    Chicago O'Hare Airport - Bus/Shuttle Center
    9:05 AM
    San Diego Airport
    San Diego Airport
    0
    JetBlue Airways
    Economy
    from $223
  • Fastest Buses Monday

  • FlixBus
    51h 5m
    0
    5:15 PM
    Chicago
    Downtown Bus Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $215
  • Greyhound US
    58h 5m
    0
    10:15 AM
    Chicago
    Union Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $179
  • Greyhound US
    69h 10m
    0
    11:10 PM
    Chicago
    Union Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $203
  • Greyhound US
    69h 30m
    0
    10:50 PM
    Chicago
    Downtown Bus Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $203
Here you will find all operators and timetables for a Bus from Chicago to San Diego

What are the most popular stations in Chicago and San Diego?

In Chicago, you will usually depart from California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, while in San Diego you will be arriving at San Ysidro Transit Center, Old Town Transit Center or Santa Fe Depot, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to San Diego from Chicago? With 16 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Diego, you can pay as low as $89 with a Flight from Frontier Airlines.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to San Diego in just 4h 27m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Diego are United Airlines, Frontier Airlines and Greyhound US, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Chicago and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to San Diego Airport, and look at flights from Chicago Midway Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Chicago to San Diego?

The most popular companies between Chicago and San Diego, are United Airlines, Frontier Airlines and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US and FlixBus

Airlines: United Airlines, Frontier Airlines, Volaris and 8 more.

All you need to know when you travel from Chicago to San Diego

Check all information on comfort and services on all modes of transports from Chicago to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Chicago to San Diego

How can I reach San Diego from Chicago?

Every day, there are on average 16 connections between Flight and Bus, with which you can get to San Diego from Chicago.

How far is San Diego from Chicago?

The distance between Chicago and San Diego is 1,730.9 miles.

What is the most ecofriendly mode of transport between Chicago and San Diego?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 75 kgs of CO2, a train 97 kgs, a car 474 kgs, and a flight 685 kgs.

What is the cheapest mode of transport from Chicago to San Diego?

You can get to San Diego with just $89 by taking a Flight from Frontier Airlines.

What is the fastest way to get from Chicago to San Diego?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 4h 27m with a Flight from United Airlines.

More routes to Chicago and to San Diego

Looking for more options? Here you can see the most popular routes to Chicago and to San Diego. Simply click on a connection, and you’ll find all the details about the route!

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.