What is the best way to travel from Chicago to San Diego?
Looking for a trip? Compare all the available Flights and Buses for the journey to San Diego from Chicago. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach San Diego from Chicago?
You can get to San Diego with just $152 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
Viva Aerobus23h 38m01:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 1:20:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 1/31/2026 10:58:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 23h 38m
-
Volaris14h 51m012:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:50 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 12:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/1/2026 1:50:00 AM. 50 Economy ticket for $206 per person are available. Travel duration is 14h 51m
-
Spirit Airlines13h 7m06:05 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:12 PMTijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 6:05:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 1/31/2026 5:12:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 13h 7m
-
Frontier Airlines12h 1m07:11 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:12 PMTijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 7:11:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 1/31/2026 5:12:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 12h 1m
-
Aeroméxico14h 46m01:04 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:50 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 1:04:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/1/2026 1:50:00 AM. 50 Economy ticket for $313 per person are available. Travel duration is 14h 46m
-
Greyhound US52h 39m012:01 PMChicagoDowntown Bus Station2:40 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 1/31/2026 12:01:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 2:40:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 52h 39m
-
Greyhound US55h 9m012:01 PMChicagoDowntown Bus Station5:10 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 1/31/2026 12:01:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 5:10:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 55h 9m
-
Greyhound US58h 20m010:00 AMChicagoUnion Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 1/31/2026 10:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 6:20:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 58h 20m
-
FlixBus51h 50m04:30 PMChicagoDowntown Bus Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 1/31/2026 4:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 6:20:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 51h 50m
Cheapest Flights Saturday
Cheapest Buses Saturday
-
FlixBus51h 50m04:30 PMChicagoDowntown Bus Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/1/2026 4:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/3/2026 6:20:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 51h 50m
-
Greyhound US58h 20m010:00 AMChicagoUnion Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/1/2026 10:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/3/2026 6:20:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 58h 20m
-
Greyhound US63h 10m011:10 PMChicagoUnion Station12:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/1/2026 11:10:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/4/2026 12:20:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 63h 10m
Cheapest Buses Sunday
-
Spirit Airlines13h 35m06:05 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 PMTijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 6:05:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/2/2026 5:40:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 13h 35m
-
Volaris26h 52m06:23 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:15 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 6:23:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 7:15:00 AM. 50 Economy ticket for $209 per person are available. Travel duration is 26h 52m
-
Viva Aerobus26h 55m012:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:50 AMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 12:55:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 1:50:00 AM. 50 Economy ticket for $232 per person are available. Travel duration is 26h 55m
-
Frontier Airlines12h 29m07:11 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 PMTijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 7:11:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/2/2026 5:40:00 PM. 50 Economy ticket for $322 per person are available. Travel duration is 12h 29m
-
Aeroméxico17h 59m03:16 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:15 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 3:16:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 7:15:00 AM. 50 Economy ticket for $330 per person are available. Travel duration is 17h 59m
Cheapest Flights Monday
-
Viva Aerobus11h 37m01:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:57 AMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 1:20:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 10:57:00 AM. 50 Economy ticket for $185 per person are available. Travel duration is 11h 37m
-
Viva Aerobus19h 45m01:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:05 PMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 1:20:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 7:05:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 19h 45m
-
Volaris32h 21m012:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:20 PMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 12:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/4/2026 7:20:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 32h 21m
-
Volaris13h 49m012:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:48 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 12:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/4/2026 12:48:00 AM. 50 Economy ticket for $215 per person are available. Travel duration is 13h 49m
-
Aeroméxico17h 59m03:16 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:15 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 3:16:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/4/2026 7:15:00 AM. 50 Economy ticket for $347 per person are available. Travel duration is 17h 59m
-
FlixBus55h 45m04:30 PMChicagoDowntown Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/3/2026 4:30:00 PM to Seaport Village, San Diego (USA) arriving at 2/5/2026 10:15:00 PM. 50 Economy ticket for $309 per person are available. Travel duration is 55h 45m
-
Greyhound US65h 0m011:10 PMChicagoUnion Station2:10 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/3/2026 11:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/6/2026 2:10:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 65h 0m
-
Greyhound US57h 35m010:00 AMChicagoUnion Station5:35 PMSan DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/3/2026 10:00:00 AM to La Jolla Village, San Diego (USA) arriving at 2/5/2026 5:35:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 57h 35m
-
Greyhound US62h 35m011:10 PMChicagoUnion Station11:45 AMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/3/2026 11:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/6/2026 11:45:00 AM. 50 Economy ticket for $311 per person are available. Travel duration is 62h 35m
-
FlixBus51h 5m04:30 PMChicagoDowntown Bus Station5:35 PMSan DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/3/2026 4:30:00 PM to La Jolla Village, San Diego (USA) arriving at 2/5/2026 5:35:00 PM. 50 Economy ticket for $313 per person are available. Travel duration is 51h 5m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
-
Volaris21h 21m011:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:20 PMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 11:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/6/2026 7:20:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 21h 21m
-
Viva Aerobus10h 40m012:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:35 AMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 12:55:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/5/2026 9:35:00 AM. 50 Economy ticket for $185 per person are available. Travel duration is 10h 40m
-
Volaris19h 2m06:23 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center11:25 PMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 6:23:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/5/2026 11:25:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 19h 2m
-
Viva Aerobus15h 55m012:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center2:50 PMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 12:55:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/5/2026 2:50:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 15h 55m
-
Aeroméxico17h 46m02:54 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:40 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 2:54:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/6/2026 6:40:00 AM. 50 Economy ticket for $279 per person are available. Travel duration is 17h 46m
-
Greyhound US62h 35m011:10 PMChicagoUnion Station11:45 AMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/5/2026 11:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/8/2026 11:45:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 62h 35m
-
Greyhound US57h 35m010:00 AMChicagoUnion Station5:35 PMSan DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/5/2026 10:00:00 AM to La Jolla Village, San Diego (USA) arriving at 2/7/2026 5:35:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 57h 35m
-
Greyhound US60h 30m011:10 PMChicagoUnion Station9:40 AMSan DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/5/2026 11:10:00 PM to La Jolla Village, San Diego (USA) arriving at 2/8/2026 9:40:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 60h 30m
-
FlixBus59h 50m012:15 AMChicagoDowntown Bus Station10:05 AMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/5/2026 12:15:00 AM to Seaport Village, San Diego (USA) arriving at 2/7/2026 10:05:00 AM. 50 Economy ticket for $251 per person are available. Travel duration is 59h 50m
Cheapest Flights Thursday
Cheapest Buses Thursday
What are the fastest trips from Chicago to San Diego?
You can get to San Diego from Chicago in just 10h 40m with a Flight from Viva Aerobus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
Frontier Airlines12h 1m07:11 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:12 PMTijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 7:11:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 1/31/2026 5:12:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 12h 1m
-
Spirit Airlines13h 7m06:05 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:12 PMTijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 6:05:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 1/31/2026 5:12:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 13h 7m
-
Aeroméxico14h 46m01:04 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:50 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 1:04:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/1/2026 1:50:00 AM. 50 Economy ticket for $313 per person are available. Travel duration is 14h 46m
-
Volaris14h 51m012:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:50 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 12:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/1/2026 1:50:00 AM. 50 Economy ticket for $206 per person are available. Travel duration is 14h 51m
-
Viva Aerobus23h 38m01:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 1/31/2026 1:20:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 1/31/2026 10:58:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 23h 38m
-
FlixBus51h 50m04:30 PMChicagoDowntown Bus Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 1/31/2026 4:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 6:20:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 51h 50m
-
Greyhound US52h 39m012:01 PMChicagoDowntown Bus Station2:40 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 1/31/2026 12:01:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 2:40:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 52h 39m
-
Greyhound US55h 9m012:01 PMChicagoDowntown Bus Station5:10 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 1/31/2026 12:01:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 5:10:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 55h 9m
-
Greyhound US58h 20m010:00 AMChicagoUnion Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 1/31/2026 10:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/2/2026 6:20:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 58h 20m
Fastest Flights Saturday
Fastest Buses Saturday
-
FlixBus51h 50m04:30 PMChicagoDowntown Bus Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/1/2026 4:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/3/2026 6:20:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 51h 50m
-
Greyhound US58h 20m010:00 AMChicagoUnion Station6:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/1/2026 10:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/3/2026 6:20:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 58h 20m
-
Greyhound US63h 10m011:10 PMChicagoUnion Station12:20 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/1/2026 11:10:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/4/2026 12:20:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 63h 10m
Fastest Buses Sunday
-
Frontier Airlines12h 29m07:11 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 PMTijuana AirportTijuana Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 7:11:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/2/2026 5:40:00 PM. 50 Economy ticket for $322 per person are available. Travel duration is 12h 29m
-
Spirit Airlines13h 35m06:05 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 PMTijuana AirportTijuana Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 6:05:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/2/2026 5:40:00 PM. 50 Economy ticket for $203 per person are available. Travel duration is 13h 35m
-
Aeroméxico17h 59m03:16 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:15 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 3:16:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 7:15:00 AM. 50 Economy ticket for $330 per person are available. Travel duration is 17h 59m
-
Volaris26h 52m06:23 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:15 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 6:23:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 7:15:00 AM. 50 Economy ticket for $209 per person are available. Travel duration is 26h 52m
-
Viva Aerobus26h 55m012:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:50 AMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/2/2026 12:55:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 1:50:00 AM. 50 Economy ticket for $232 per person are available. Travel duration is 26h 55m
Fastest Flights Monday
-
Viva Aerobus11h 37m01:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:57 AMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 1:20:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 10:57:00 AM. 50 Economy ticket for $185 per person are available. Travel duration is 11h 37m
-
Volaris13h 49m012:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:48 AMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 12:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/4/2026 12:48:00 AM. 50 Economy ticket for $215 per person are available. Travel duration is 13h 49m
-
Aeroméxico17h 59m03:16 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:15 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 3:16:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/4/2026 7:15:00 AM. 50 Economy ticket for $347 per person are available. Travel duration is 17h 59m
-
Viva Aerobus19h 45m01:20 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:05 PMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 1:20:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/3/2026 7:05:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 19h 45m
-
Volaris32h 21m012:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:20 PMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/3/2026 12:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/4/2026 7:20:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 32h 21m
-
FlixBus51h 5m04:30 PMChicagoDowntown Bus Station5:35 PMSan DiegoLa Jolla Village0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/3/2026 4:30:00 PM to La Jolla Village, San Diego (USA) arriving at 2/5/2026 5:35:00 PM. 50 Economy ticket for $313 per person are available. Travel duration is 51h 5m
-
FlixBus55h 45m04:30 PMChicagoDowntown Bus Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/3/2026 4:30:00 PM to Seaport Village, San Diego (USA) arriving at 2/5/2026 10:15:00 PM. 50 Economy ticket for $309 per person are available. Travel duration is 55h 45m
-
Greyhound US57h 35m010:00 AMChicagoUnion Station5:35 PMSan DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/3/2026 10:00:00 AM to La Jolla Village, San Diego (USA) arriving at 2/5/2026 5:35:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 57h 35m
-
Greyhound US62h 35m011:10 PMChicagoUnion Station11:45 AMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/3/2026 11:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/6/2026 11:45:00 AM. 50 Economy ticket for $311 per person are available. Travel duration is 62h 35m
-
Greyhound US65h 0m011:10 PMChicagoUnion Station2:10 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/3/2026 11:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/6/2026 2:10:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 65h 0m
Fastest Flights Tuesday
Fastest Buses Tuesday
-
Viva Aerobus10h 40m012:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:35 AMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 12:55:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/5/2026 9:35:00 AM. 50 Economy ticket for $185 per person are available. Travel duration is 10h 40m
-
Viva Aerobus15h 55m012:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center2:50 PMTijuana AirportTijuana Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 12:55:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/5/2026 2:50:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 15h 55m
-
Aeroméxico17h 46m02:54 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:40 AMTijuana AirportTijuana Airport0EconomyA Flight from Aeroméxico goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 2:54:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/6/2026 6:40:00 AM. 50 Economy ticket for $279 per person are available. Travel duration is 17h 46m
-
Volaris19h 2m06:23 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center11:25 PMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 6:23:00 AM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/5/2026 11:25:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 19h 2m
-
Volaris21h 21m011:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center7:20 PMTijuana AirportTijuana Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 2/5/2026 11:59:00 PM to Tijuana Airport, Tijuana Airport (Mexico) arriving at 2/6/2026 7:20:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 21h 21m
-
Greyhound US57h 35m010:00 AMChicagoUnion Station5:35 PMSan DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/5/2026 10:00:00 AM to La Jolla Village, San Diego (USA) arriving at 2/7/2026 5:35:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 57h 35m
-
FlixBus59h 50m012:15 AMChicagoDowntown Bus Station10:05 AMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/5/2026 12:15:00 AM to Seaport Village, San Diego (USA) arriving at 2/7/2026 10:05:00 AM. 50 Economy ticket for $251 per person are available. Travel duration is 59h 50m
-
Greyhound US60h 30m011:10 PMChicagoUnion Station9:40 AMSan DiegoLa Jolla Village0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/5/2026 11:10:00 PM to La Jolla Village, San Diego (USA) arriving at 2/8/2026 9:40:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 60h 30m
-
Greyhound US62h 35m011:10 PMChicagoUnion Station11:45 AMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/5/2026 11:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/8/2026 11:45:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 62h 35m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Chicago to San Diego
What are the most popular stations in Chicago and San Diego?
In Chicago, you will usually depart from California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, while in San Diego you will be arriving at San Ysidro Transit Center, University Av & Bancroft St Bus Stop or Old Town Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Diego from Chicago? With 7 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Diego, you can pay as low as $152 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Viva Aerobus: you will get to San Diego in just 10h 40m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Diego are Greyhound US, Viva Aerobus and Volaris, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and San Diego is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to San Diego Airport, and look at flights from Chicago Midway Airport, and landing at Tijuana Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to San Diego?
The most popular companies between Chicago and San Diego, are Greyhound US, Viva Aerobus and Volaris. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Viva Aerobus, Volaris, Aeroméxico and 2 more.
All you need to know when you travel from Chicago to San Diego
Check all information on comfort and services on all modes of transports from Chicago to San Diego. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to San Diego
How can I reach San Diego from Chicago?
Every day, there are on average 7 connections between Flight and Bus, with which you can get to San Diego from Chicago.
How far is San Diego from Chicago?
The distance between Chicago and San Diego is 1,730.9 miles.
What is the most ecofriendly mode of transport between Chicago and San Diego?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 75 kgs of CO2, a train 97 kgs, a car 474 kgs, and a flight 685 kgs.
What is the cheapest mode of transport from Chicago to San Diego?
You can get to San Diego with just $152 by taking a Bus from FlixBus.
What is the fastest way to get from Chicago to San Diego?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Diego in just 10h 40m with a Flight from Viva Aerobus.
More routes to Chicago and to San Diego
Looking for more options? Here you can see the most popular routes to Chicago and to San Diego. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Buffalo, NY to Chicago
- Cincinnati to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Guadalajara, JC to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- Louisville, KY to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Monterrey, NL to Chicago
- Nashville to Chicago
- New York to Chicago
- Nuevo Laredo to Chicago
- Pearson Toronto Airport to Chicago
- San Antonio, TX to Chicago
- Santiago de Queretaro to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Tulsa to Chicago
- Trips to San Diego
- Bakersfield, CA to San Diego
- El Paso, TX to San Diego
- Houston to San Diego
- Las Vegas to San Diego
- Mexico City to San Diego
- New York to San Diego
- Pasco, WA to San Diego
- Phoenix, AZ to San Diego
- Salt Lake City, UT to San Diego
- San Francisco to San Diego
- San Jose, CA to San Diego
- Yakima, WA to San Diego
