Compare all timetables for the bus from San Francisco to San Diego
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 10:40 PM | San Francisco | Salesforce Transit Center | 11:45 AM | San Diego | Old Town Transit Center | Economy | $50 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 3/24/2026 10:40:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/25/2026 11:45:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 13h 5m
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| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Salesforce Transit Center | 11:50 PM | San Diego | Old Town Transit Center | Economy | $68 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 3/24/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 3/24/2026 11:50:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 17h 20m
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| FlixBus | 13h 55m | 8:20 AM | San Francisco | 5th/Townsend | 10:15 PM | San Diego | Seaport Village | Economy | $68 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/24/2026 8:20:00 AM to Seaport Village, San Diego (USA) arriving at 3/24/2026 10:15:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 13h 55m
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| FlixBus | 15h 30m | 8:20 AM | San Francisco | 5th/Townsend | 11:50 PM | San Diego | Old Town Transit Center | Economy | $69 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/24/2026 8:20:00 AM to Old Town Transit Center, San Diego (USA) arriving at 3/24/2026 11:50:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 15h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 10:40 PM | San Francisco | Bus Station Transbay | 11:45 AM | San Diego | Old Town Transit Center | Economy | $59 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/25/2026 10:40:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/26/2026 11:45:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 13h 5m
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| Greyhound US | 13h 40m | 10:40 PM | San Francisco | Bus Station Transbay | 12:20 PM | San Diego | San Ysidro Transit Center | Economy | $59 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/25/2026 10:40:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 3/26/2026 12:20:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 13h 40m
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| FlixBus | 15h 30m | 8:20 AM | San Francisco | 5th/Townsend | 11:50 PM | San Diego | Old Town Transit Center | Economy | $65 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/25/2026 8:20:00 AM to Old Town Transit Center, San Diego (USA) arriving at 3/25/2026 11:50:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 15h 30m
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| Greyhound US | 22h 10m | 4:00 PM | San Francisco | Bus Station Transbay | 2:10 PM | San Diego | Old Town Transit Center | Economy | $66 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/25/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/26/2026 2:10:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 22h 10m
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| FlixBus | 13h 55m | 8:20 AM | San Francisco | 5th/Townsend | 10:15 PM | San Diego | Seaport Village | Economy | $66 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/25/2026 8:20:00 AM to Seaport Village, San Diego (USA) arriving at 3/25/2026 10:15:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 55m | 6:30 AM | San Francisco | Bus Station Transbay | 12:25 AM | San Diego | San Ysidro Transit Center | Economy | $96 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/27/2026 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 3/28/2026 12:25:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 17h 55m
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| Greyhound US | 13h 40m | 10:40 PM | San Francisco | Bus Station Transbay | 12:20 PM | San Diego | San Ysidro Transit Center | Economy | $115 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/27/2026 10:40:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 3/28/2026 12:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 13h 40m
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Save more than 9%21h 5mSan Francisco7 mi4:35 PMOaklandW Oakland BART Station1:40 PMSan DiegoLa Jolla Village0 miEconomyA Bus from goes from W Oakland BART Station, Oakland (USA) at 3/27/2026 4:35:00 PM to La Jolla Village, San Diego (USA) arriving at 3/28/2026 1:40:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 21h 5m
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FlixBus14h 25m08:20 AMSan Francisco5th/Townsend9:15 AMSan Jose, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/25/2026 8:20:00 AM to Bus Stop, San Jose, CA (USA) arriving at 3/25/2026 9:15:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 0h 55m
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FlixBus13h 20m09:25 AMSan Jose, CABus Stop10:45 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Bus Stop, San Jose, CA (USA) at 3/25/2026 9:25:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 3/25/2026 10:45:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 20m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Salesforce Transit Center | 11:50 PM | San Diego | Old Town Transit Center | Economy | $93 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 3/28/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 3/28/2026 11:50:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 17h 20m
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| Greyhound US | 22h 10m | 4:00 PM | San Francisco | Salesforce Transit Center | 2:10 PM | San Diego | Old Town Transit Center | Economy | $93 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 3/28/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/29/2026 2:10:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 22h 10m
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| Greyhound US | 13h 5m | 10:40 PM | San Francisco | Salesforce Transit Center | 11:45 AM | San Diego | Old Town Transit Center | Economy | $101 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 3/28/2026 10:40:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/29/2026 11:45:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 13h 5m
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Save more than 45%14h 10mSan Francisco7 mi8:00 AMOaklandW Oakland BART Station10:10 PMSan DiegoSeaport Village0 miEconomyA Bus from goes from W Oakland BART Station, Oakland (USA) at 3/28/2026 8:00:00 AM to Seaport Village, San Diego (USA) arriving at 3/28/2026 10:10:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 14h 10m
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FlixBus14h 25m08:20 AMSan Francisco5th/Townsend9:15 AMSan Jose, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/25/2026 8:20:00 AM to Bus Stop, San Jose, CA (USA) arriving at 3/25/2026 9:15:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 0h 55m
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FlixBus13h 20m09:25 AMSan Jose, CABus Stop10:45 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Bus Stop, San Jose, CA (USA) at 3/25/2026 9:25:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 3/25/2026 10:45:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 20m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 55m | 6:30 AM | San Francisco | Bus Station Transbay | 12:25 AM | San Diego | San Ysidro Transit Center | Economy | $80 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/29/2026 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 3/30/2026 12:25:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 17h 55m
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| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Bus Station Transbay | 11:50 PM | San Diego | Old Town Transit Center | Economy | $82 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/29/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 3/29/2026 11:50:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 17h 20m
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| Greyhound US | 22h 10m | 4:00 PM | San Francisco | Bus Station Transbay | 2:10 PM | San Diego | Old Town Transit Center | Economy | $82 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/29/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/30/2026 2:10:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 22h 10m
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| Greyhound US | 21h 40m | 4:00 PM | San Francisco | Bus Station Transbay | 1:40 PM | San Diego | La Jolla Village | Economy | $83 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/29/2026 4:00:00 PM to La Jolla Village, San Diego (USA) arriving at 3/30/2026 1:40:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 21h 40m
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| Greyhound US | 13h 5m | 10:40 PM | San Francisco | Bus Station Transbay | 11:45 AM | San Diego | Old Town Transit Center | Economy | $112 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 3/29/2026 10:40:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/30/2026 11:45:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 13h 5m
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FlixBus14h 25m08:20 AMSan Francisco5th/Townsend9:15 AMSan Jose, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/25/2026 8:20:00 AM to Bus Stop, San Jose, CA (USA) arriving at 3/25/2026 9:15:00 AM. 50 Economy ticket for $11 per person are available. Travel duration is 0h 55m
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FlixBus13h 20m09:25 AMSan Jose, CABus Stop10:45 PMSan DiegoSan Ysidro Transit Center0EconomyA Bus from FlixBus goes from Bus Stop, San Jose, CA (USA) at 3/25/2026 9:25:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 3/25/2026 10:45:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 13h 20m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 13h 5m | 10:40 PM | San Francisco | Salesforce Transit Center | 11:45 AM | San Diego | Old Town Transit Center | Economy | $95 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 3/30/2026 10:40:00 PM to Old Town Transit Center, San Diego (USA) arriving at 3/31/2026 11:45:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 13h 5m
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| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Salesforce Transit Center | 11:50 PM | San Diego | Old Town Transit Center | Economy | $104 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 3/30/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 3/30/2026 11:50:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 17h 20m
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| FlixBus | 14h 45m | 7:30 AM | San Francisco | 5th/Townsend | 10:15 PM | San Diego | Seaport Village | Economy | $148 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/30/2026 7:30:00 AM to Seaport Village, San Diego (USA) arriving at 3/30/2026 10:15:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 14h 45m
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| FlixBus | 16h 20m | 7:30 AM | San Francisco | 5th/Townsend | 11:50 PM | San Diego | Old Town Transit Center | Economy | $150 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 3/30/2026 7:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 3/30/2026 11:50:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 16h 20m
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FlixBus14h 45m07:30 AMSan Francisco5th/Townsend4:15 PMLos AngelesUnion Station0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 4/1/2026 7:30:00 AM to Union Station, Los Angeles (USA) arriving at 4/1/2026 4:15:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 8h 45m
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FlixBus3h 45m06:30 PMLos AngelesUnion Station10:15 PMSan DiegoSeaport Village0EconomyA Bus from FlixBus goes from Union Station, Los Angeles (USA) at 4/1/2026 6:30:00 PM to Seaport Village, San Diego (USA) arriving at 4/1/2026 10:15:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 3h 45m
Waiting Time 2h 15m -
Best Price Offer: The price for the cheapest bus from San Francisco to San Diego is $50 on 3/24/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between San Francisco and San Diego
Facts about the bus from San Francisco to San Diego
Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from San Francisco to San Diego in one click! Book your bus ticket from San Francisco to San Diego starting from $50!
| Cheapest Bus | $50 |
| Fastest Bus | 13h 5m |
| Earliest Bus | 6:30 AM |
| Latest Bus | 10:40 PM |
| Daily Bus Routes | 4 Ø |
| Distance | 457.7 miles |
| Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from San Francisco to San Diego
Every day, 4 buses from 2 bus companies leave San Francisco for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.
The cheapest time to travel from San Francisco to San Diego
How to save money travelling from San Francisco to San Diego
Book the ticket from San Francisco to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to San Diego are also emptier.Beloved bus companies from San Francisco to San Diego
Greyhound US from San Francisco to San Diego
Here you will find the key facts about the Greyhound US bus route San Francisco to San Diego:
| Cheapest Price | $50 |
| Fastest Bus | 13h 5m |
| Earliest Bus | 6:30 AM |
| Last Bus | 10:40 PM |
| Daily Connections | 3 Ø |
| Found on | 3/23/2026 |
FlixBus from San Francisco to San Diego
Here you will find the key facts about the FlixBus bus route San Francisco to San Diego:
| Cheapest Price | $65 |
| Fastest Bus | 13h 25m |
| Earliest Bus | 8:20 AM |
| Last Bus | 7:30 AM |
| Daily Connections | 2 Ø |
| Found on | 3/23/2026 |
All bus stations and stops in San Francisco and San Diego
In the map below, you can see where to find all bus stations in San Francisco and San Diego.
Compare the bus with other modes of transport
Service and Comfort on the bus from San Francisco to San Diego
FAQs about the San Francisco to San Diego bus
How much does a San Francisco San Diego bus trip cost?
How much could I save by comparing buses from San Francisco to San Diego?
On average, how many connections are available from San Francisco to San Diego each day?
How long does a bus journey from San Francisco to San Diego take?
What time is the first bus from San Francisco to San Diego?
What time is the last bus from San Francisco to San Diego?
Which bus companies operate the San Francisco San Diego route?
Is there a direct bus between San Francisco and San Diego?
What can I take with me on the San Francisco to San Diego bus route?
What equipment is available for the San Francisco San Diego bus route?
How does CheckMyBus find the best bus deals from San Francisco to San Diego?
How does CheckMyBus technology work for trips from San Francisco to San Diego?
Available seat classes which are offered on the bus route San Francisco to San Diego
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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