Bus from San Francisco to San Diego from $46

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Compare all timetables for the bus from San Francisco to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Francisco to San Diego from various bus operators like FlixBus or Greyhound US for the next days.
today
from $60
tomorrow
from $54
Wednesday
from $46
Thursday
from $64
Friday
from $74
Saturday
from $63
Sunday

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    17h 20m
    0
    6:30 AM
    San Francisco
    Bus Station Transbay
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $60
  • FlixBus
    14h 20m
    0
    9:30 AM
    San Francisco
    5th/Townsend
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $60
  • Greyhound US
    19h 0m
    0
    4:00 PM
    San Francisco
    Bus Station Transbay
    11:00 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $61
  • FlixBus
    16h 15m
    0
    6:45 PM
    San Francisco
    5th/Townsend
    11:00 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $61
  • FlixBus
    14h 55m
    0
    9:30 AM
    San Francisco
    5th/Townsend
    12:25 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $61

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    17h 20m
    0
    6:30 AM
    San Francisco
    Bus Station Transbay
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $54
  • FlixBus
    11h 50m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    11:15 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $54
  • FlixBus
    16h 35m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    4:00 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $54
  • FlixBus
    17h 0m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $55
  • Greyhound US
    17h 30m
    0
    4:00 PM
    San Francisco
    Bus Station Transbay
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $56

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Greyhound US
    15h 30m
    0
    6:00 AM
    San Francisco
    Salesforce Transit Center
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $46
  • Greyhound US
    17h 20m
    0
    6:30 AM
    San Francisco
    Salesforce Transit Center
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $46
  • FlixBus
    13h 50m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    1:15 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $46
  • FlixBus
    14h 10m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    1:35 PM
    San Diego
    SDSU Transit Center
    0
    FlixBus
    Economy
    $46
  • Greyhound US
    17h 30m
    0
    4:00 PM
    San Francisco
    Salesforce Transit Center
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $47

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    11h 50m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    11:15 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $64
  • FlixBus
    13h 50m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    1:15 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $64
  • Greyhound US
    14h 15m
    0
    11:35 AM
    San Francisco
    Salesforce Transit Center
    1:50 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $65
  • FlixBus
    18h 20m
    0
    7:30 AM
    San Francisco
    5th/Townsend
    1:50 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $65
  • Greyhound US
    12h 35m
    0
    10:40 PM
    San Francisco
    Salesforce Transit Center
    11:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $72

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    12h 35m
    0
    10:40 PM
    San Francisco
    Bus Station Transbay
    11:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $74
  • FlixBus
    10h 45m
    0
    10:00 PM
    San Francisco
    5th/Townsend
    8:45 AM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $74
  • FlixBus
    11h 15m
    0
    10:00 PM
    San Francisco
    5th/Townsend
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $74
  • Greyhound US
    12h 55m
    0
    6:00 AM
    San Francisco
    Bus Station Transbay
    6:55 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $76
  • Greyhound US
    14h 35m
    0
    6:30 AM
    San Francisco
    Bus Station Transbay
    9:05 PM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $76
  • Did you know that if you travel from San Francisco to San Diego via San Jose, CA, you can save more than $13? You can find the corresponding connections below.
    • Busbud
      13h 50m
      0
      11:25 PM
      San Francisco
      5th/Townsend
      12:35 AM
      San Jose, CA
      Bus Stop
      0
      Busbud
      Economy
      $10
      • Waiting Time 0h 5m
    • Busbud
      12h 35m
      0
      12:40 AM
      San Jose, CA
      Bus Stop
      1:15 PM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $51
    Travel time is 3h 5m longer, but you will save $13

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    14h 15m
    0
    11:35 AM
    San Francisco
    Salesforce Transit Center
    1:50 AM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $63
  • FlixBus
    14h 10m
    0
    11:40 AM
    San Francisco
    5th/Townsend
    1:50 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $63
  • FlixBus
    13h 50m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    1:15 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $63
  • FlixBus
    11h 50m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    11:15 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $63
  • Greyhound US
    17h 20m
    0
    6:30 AM
    San Francisco
    Salesforce Transit Center
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $64

Frequency of bus connections between San Francisco and San Diego

See here how frequent the connections between San Francisco and San Diego are, during different times and days of the week.
Saturday is the busiest day, with more than 44 daily buses from San Francisco to San Diego. Tuesday has instead the fewest connections, with only 13 daily coaches between San Francisco and San Diego.
The busiest time of the day is the Evening, with 93 buses from San Francisco to San Diego, while Afternoon sees the fewest connections between San Francisco and San Diego, with 30 offers.

Facts about the bus from San Francisco to San Diego

Compare all providers like FlixBus and Greyhound US that travel 31 times every day by bus from San Francisco to San Diego in one click! Book your bus ticket from San Francisco to San Diego starting from $46!

Cheapest Bus $46
Fastest Bus 10h 45m
Earliest Bus 6:30 AM
Latest Bus 11:25 PM
Daily Bus Routes 31 Ø
Distance 457.7 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from San Francisco to San Diego

Every day, 31 buses from 2 bus companies leave San Francisco for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/18
Monday 05/19
$78
Tuesday 05/20
$64
Wednesday 05/21
$46
Thursday 05/22
$64
Friday 05/23
$74
Saturday 05/24
$63
Sunday 05/25
Monday 05/26
$66
Tuesday 05/27
$71
Wednesday 05/28
Thursday 05/29
$55
Friday 05/30
Saturday 05/31
Sunday 06/01
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07
Sunday 06/08
$58
Monday 06/09
$53
Tuesday 06/10
$43
Wednesday 06/11
Thursday 06/12
Friday 06/13
$46
Saturday 06/14

The cheapest time to travel from San Francisco to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to San Diego, for the next 30 days.
With a price starting from $46, Wednesday is the cheapest day for a bus from San Francisco to San Diego. Friday instead is the most expensive day with prices starting from $74.
Evening is the cheapest day time for bus tickets from San Francisco to San Diego, with $46. Afternoon is the most expensive time of the day with prices starting from $47.

How to save money travelling from San Francisco to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to San Diego are also emptier.

Beloved bus companies from San Francisco to San Diego

These are the most booked bus companies between San Francisco to San Diego from our users.

Greyhound US from San Francisco to San Diego

Greyhound US

Here you will find the key facts about the Greyhound US bus route San Francisco to San Diego:

Cheapest Price $46
Fastest Bus 12h 35m
Earliest Bus 6:30 AM
Last Bus 10:40 PM
Daily Connections 13 Ø
Found on 5/18/2025

All bus stations and stops in San Francisco and San Diego

In the map below, you can see where to find all bus stations in San Francisco and San Diego.

Service and Comfort on the bus from San Francisco to San Diego

Want to know which seat classes are available on the buses from San Francisco to San Diego? Or which bus companies serve the route San Francisco to San Diego? Below you will find answers to your questions.

FAQs about the San Francisco to San Diego bus

How much does a San Francisco San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $46 and takes 14h 10m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Francisco to San Diego?

This route is offered by 2 companies with a range of ticket prices between $46 and $118. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Francisco to San Diego each day?

Every day, the San Francisco to San Diego bus route is served by approximately 31 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to San Diego take?

The fastest bus from San Francisco to San Diego is offered by FlixBus and takes 10h 45m. Bus tickets for this connection cost $70. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to San Diego?

The earliest bus arriving in San Diego from San Francisco starts at 6:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to San Diego?

The latest bus trip departing from San Francisco for San Diego starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco San Diego route?

When traveling by bus from San Francisco to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and San Diego?

You can check all the direct connections between San Francisco and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the San Francisco to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to San Diego on your planned travel date.

Available seat classes which are offered on the bus route San Francisco to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to San Diego

Here’s an overview of the most popular bus routes to San Francisco and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
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From Salt Lake City, UT to San Francisco bus From Salt Lake City, UT to San Francisco bus
El Centro, CA to San Diego bus El Centro, CA to San Diego bus
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From San Jose, CA to San Diego bus From San Jose, CA to San Diego bus
Riverside, CA to San Diego bus Riverside, CA to San Diego bus
Popular Airport Shuttles to San Francisco and to San Diego
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