Compare all timetables for the bus from San Francisco to San Diego
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 24h 25m | 4:00 PM | San Francisco | Salesforce Transit Center | 4:25 PM | San Diego | Old Town Transit Center | Economy | $60 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/23/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/24/2026 4:25:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 24h 25m
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| Greyhound US | 13h 50m | 10:30 PM | San Francisco | Bus Station Transbay | 12:20 PM | San Diego | San Ysidro Transit Center | Economy | $174 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/23/2026 10:30:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/24/2026 12:20:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 13h 50m
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| Greyhound US | 13h 15m | 10:30 PM | San Francisco | Salesforce Transit Center | 11:45 AM | San Diego | Old Town Transit Center | Economy | $175 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/23/2026 10:30:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/24/2026 11:45:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 13h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Salesforce Transit Center | 11:50 PM | San Diego | Old Town Transit Center | Economy | $57 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/24/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/24/2026 11:50:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 20m
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| FlixBus | 16h 20m | 7:30 AM | San Francisco | 5th/Townsend | 11:50 PM | San Diego | Old Town Transit Center | Economy | $57 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/24/2026 7:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/24/2026 11:50:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 16h 20m
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| Greyhound US | 24h 25m | 4:00 PM | San Francisco | Salesforce Transit Center | 4:25 PM | San Diego | Old Town Transit Center | Economy | $58 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/24/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/25/2026 4:25:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 24h 25m
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| FlixBus | 14h 45m | 11:25 PM | San Francisco | 5th/Townsend | 2:10 PM | San Diego | Old Town Transit Center | Economy | $58 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/24/2026 11:25:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/25/2026 2:10:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 45m
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| FlixBus | 14h 45m | 7:30 AM | San Francisco | 5th/Townsend | 10:15 PM | San Diego | Seaport Village | Economy | $58 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/24/2026 7:30:00 AM to Seaport Village, San Diego (USA) arriving at 6/24/2026 10:15:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 14h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 26h 20m | 4:00 PM | San Francisco | Salesforce Transit Center | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $78 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/25/2026 4:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/26/2026 6:20:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 26h 20m
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| Greyhound US | 23h 55m | 4:00 PM | San Francisco | Bus Station Transbay | 3:55 PM | San Diego | La Jolla Village | Economy | $78 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/25/2026 4:00:00 PM to La Jolla Village, San Diego (USA) arriving at 6/26/2026 3:55:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 23h 55m
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| FlixBus | 14h 15m | 7:30 AM | San Francisco | 5th/Townsend | 9:45 PM | San Diego | La Jolla Village | Economy | $78 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/25/2026 7:30:00 AM to La Jolla Village, San Diego (USA) arriving at 6/25/2026 9:45:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 14h 15m
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| FlixBus | 14h 15m | 11:25 PM | San Francisco | 5th/Townsend | 1:40 PM | San Diego | La Jolla Village | Economy | $78 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/25/2026 11:25:00 PM to La Jolla Village, San Diego (USA) arriving at 6/26/2026 1:40:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 14h 15m
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| FlixBus | 17h 45m | 11:25 PM | San Francisco | 5th/Townsend | 5:10 PM | San Diego | San Ysidro Transit Center | Economy | $78 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/25/2026 11:25:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/26/2026 5:10:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 17h 45m
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FlixBus14h 45m011:25 PMSan Francisco5th/Townsend12:05 PMIrvine, CAUC Irvine0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/24/2026 11:25:00 PM to UC Irvine, Irvine, CA (USA) arriving at 6/25/2026 12:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 12h 40m
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FlixBus2h 0m012:10 PMIrvine, CAUC Irvine2:10 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from UC Irvine, Irvine, CA (USA) at 6/25/2026 12:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/25/2026 2:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 0m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Salesforce Transit Center | 11:50 PM | San Diego | Old Town Transit Center | Economy | $93 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/26/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/26/2026 11:50:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 17h 20m
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| Greyhound US | 24h 25m | 4:00 PM | San Francisco | Salesforce Transit Center | 4:25 PM | San Diego | Old Town Transit Center | Economy | $95 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/26/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/27/2026 4:25:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 24h 25m
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| Greyhound US | 17h 55m | 6:30 AM | San Francisco | Salesforce Transit Center | 12:25 AM | San Diego | San Ysidro Transit Center | Economy | $96 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/26/2026 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/27/2026 12:25:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 17h 55m
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| FlixBus | 14h 45m | 11:25 PM | San Francisco | 5th/Townsend | 2:10 PM | San Diego | Old Town Transit Center | Economy | $114 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/26/2026 11:25:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/27/2026 2:10:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 14h 45m
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| FlixBus | 14h 15m | 11:25 PM | San Francisco | 5th/Townsend | 1:40 PM | San Diego | La Jolla Village | Economy | $119 |
A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/26/2026 11:25:00 PM to La Jolla Village, San Diego (USA) arriving at 6/27/2026 1:40:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 14h 15m
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Save more than 20%12h 10mSan Francisco7 mi11:35 PMOaklandGreyhound Bus Station11:45 AMSan DiegoOld Town Transit Center0 miEconomyA Bus from goes from Greyhound Bus Station, Oakland (USA) at 6/26/2026 11:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/27/2026 11:45:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 12h 10m
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FlixBus14h 45m011:25 PMSan Francisco5th/Townsend12:05 PMIrvine, CAUC Irvine0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/24/2026 11:25:00 PM to UC Irvine, Irvine, CA (USA) arriving at 6/25/2026 12:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 12h 40m
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FlixBus2h 0m012:10 PMIrvine, CAUC Irvine2:10 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from UC Irvine, Irvine, CA (USA) at 6/25/2026 12:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/25/2026 2:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 0m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Salesforce Transit Center | 11:50 PM | San Diego | Old Town Transit Center | Economy | $66 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/27/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/27/2026 11:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 17h 20m
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| Greyhound US | 24h 25m | 4:00 PM | San Francisco | Salesforce Transit Center | 4:25 PM | San Diego | Old Town Transit Center | Economy | $66 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/27/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/28/2026 4:25:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 24h 25m
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| Greyhound US | 26h 20m | 4:00 PM | San Francisco | Salesforce Transit Center | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $68 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/27/2026 4:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/28/2026 6:20:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 26h 20m
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| Greyhound US | 17h 55m | 6:30 AM | San Francisco | Bus Station Transbay | 12:25 AM | San Diego | San Ysidro Transit Center | Economy | $70 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/27/2026 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/28/2026 12:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 55m
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| Greyhound US | 13h 15m | 10:30 PM | San Francisco | Salesforce Transit Center | 11:45 AM | San Diego | Old Town Transit Center | Economy | $125 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/27/2026 10:30:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/28/2026 11:45:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 13h 15m
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FlixBus14h 45m011:25 PMSan Francisco5th/Townsend12:05 PMIrvine, CAUC Irvine0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/24/2026 11:25:00 PM to UC Irvine, Irvine, CA (USA) arriving at 6/25/2026 12:05:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 12h 40m
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FlixBus2h 0m012:10 PMIrvine, CAUC Irvine2:10 PMSan DiegoOld Town Transit Center0EconomyA Bus from FlixBus goes from UC Irvine, Irvine, CA (USA) at 6/25/2026 12:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/25/2026 2:10:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 0m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 20m | 6:30 AM | San Francisco | Salesforce Transit Center | 11:50 PM | San Diego | Old Town Transit Center | Economy | $50 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/28/2026 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 6/28/2026 11:50:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 17h 20m
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| Greyhound US | 24h 25m | 4:00 PM | San Francisco | Salesforce Transit Center | 4:25 PM | San Diego | Old Town Transit Center | Economy | $50 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/28/2026 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 6/29/2026 4:25:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 24h 25m
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| Greyhound US | 26h 20m | 4:00 PM | San Francisco | Salesforce Transit Center | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $76 |
A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 6/28/2026 4:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 6/29/2026 6:20:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 26h 20m
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| Greyhound US | 23h 55m | 4:00 PM | San Francisco | Bus Station Transbay | 3:55 PM | San Diego | La Jolla Village | Economy | $77 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/28/2026 4:00:00 PM to La Jolla Village, San Diego (USA) arriving at 6/29/2026 3:55:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 23h 55m
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| Greyhound US | 17h 55m | 6:30 AM | San Francisco | Bus Station Transbay | 12:25 AM | San Diego | San Ysidro Transit Center | Economy | $79 |
A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/28/2026 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 6/29/2026 12:25:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
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Best Price Offer: The price for the cheapest bus from San Francisco to San Diego is $50 on 6/28/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between San Francisco and San Diego
Facts about the bus from San Francisco to San Diego
Compare all providers like Greyhound US and FlixBus that travel 11 times every day by bus from San Francisco to San Diego in one click! Book your bus ticket from San Francisco to San Diego starting from $50!
| Cheapest Bus | $50 |
| Fastest Bus | 12h 40m |
| Earliest Bus | 4:00 PM |
| Latest Bus | 10:30 PM |
| Daily Bus Routes | 11 Ø |
| Distance | 457.7 miles |
| Bus Companies | Greyhound US and FlixBus |
Cheapest bus connections from San Francisco to San Diego
Every day, 11 buses from 2 bus companies leave San Francisco for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/23/2026 and for the following days.
The cheapest time to travel from San Francisco to San Diego
How to save money travelling from San Francisco to San Diego
Book the ticket from San Francisco to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to San Diego are also emptier.Beloved bus companies from San Francisco to San Diego
Greyhound US from San Francisco to San Diego
Here you will find the key facts about the Greyhound US bus route San Francisco to San Diego:
| Cheapest Price | $50 |
| Fastest Bus | 12h 40m |
| Earliest Bus | 4:00 PM |
| Last Bus | 10:30 PM |
| Daily Connections | 8 Ø |
| Found on | 6/23/2026 |
All bus stations and stops in San Francisco and San Diego
In the map below, you can see where to find all bus stations in San Francisco and San Diego.
Service and Comfort on the bus from San Francisco to San Diego
FAQs about the San Francisco to San Diego bus
How much does a San Francisco San Diego bus trip cost?
How much could I save by comparing buses from San Francisco to San Diego?
On average, how many connections are available from San Francisco to San Diego each day?
How long does a bus journey from San Francisco to San Diego take?
What time is the first bus from San Francisco to San Diego?
What time is the last bus from San Francisco to San Diego?
Which bus companies operate the San Francisco San Diego route?
Is there a direct bus between San Francisco and San Diego?
What can I take with me on the San Francisco to San Diego bus route?
What equipment is available for the San Francisco San Diego bus route?
How does CheckMyBus find the best bus deals from San Francisco to San Diego?
How does CheckMyBus technology work for trips from San Francisco to San Diego?
Available seat classes which are offered on the bus route San Francisco to San Diego
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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