Bus San Francisco to San Diego: Compare prices and save money

Compare all timetables for the bus from San Francisco to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Francisco to San Diego from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

$67

Sunday

Monday

$53

Tuesday

Wednesday

$66

Thursday

$111

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 10m	4:00 PM	San Francisco	Bus Station Transbay	2:10 PM	San Diego	Old Town Transit Center	Economy	$67	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/6/2025 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/7/2025 2:10:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 22h 10m
Greyhound US	21h 40m	4:00 PM	San Francisco	Bus Station Transbay	1:40 PM	San Diego	La Jolla Village	Economy	$68	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/6/2025 4:00:00 PM to La Jolla Village, San Diego (USA) arriving at 12/7/2025 1:40:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 21h 40m
Greyhound US	17h 20m	6:30 AM	San Francisco	Bus Station Transbay	11:50 PM	San Diego	Old Town Transit Center	Economy	$87	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/6/2025 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/6/2025 11:50:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 20m
Greyhound US	17h 55m	6:30 AM	San Francisco	Bus Station Transbay	12:25 AM	San Diego	San Ysidro Transit Center	Economy	$92	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/6/2025 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/7/2025 12:25:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 17h 55m
Greyhound US	13h 40m	10:40 PM	San Francisco	Bus Station Transbay	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$146	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/6/2025 10:40:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/7/2025 12:20:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 13h 40m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	15h 20m	8:30 AM	San Francisco	5th/Townsend	11:50 PM	San Diego	Old Town Transit Center	Economy	$53	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/8/2025 8:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 11:50:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 15h 20m
FlixBus	17h 0m	11:25 PM	San Francisco	5th/Townsend	4:25 PM	San Diego	Old Town Transit Center	Economy	$53	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/8/2025 11:25:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/9/2025 4:25:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 17h 0m
FlixBus	12h 20m	11:25 PM	San Francisco	5th/Townsend	11:45 AM	San Diego	Old Town Transit Center	Economy	$54	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/8/2025 11:25:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/9/2025 11:45:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 12h 20m
Greyhound US	17h 20m	6:30 AM	San Francisco	Salesforce Transit Center	11:50 PM	San Diego	Old Town Transit Center	Economy	$56	A Bus from Greyhound US goes from Salesforce Transit Center, San Francisco (USA) at 12/8/2025 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 11:50:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 17h 20m
Greyhound US	17h 55m	6:30 AM	San Francisco	Bus Station Transbay	12:25 AM	San Diego	San Ysidro Transit Center	Economy	$70	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/8/2025 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/9/2025 12:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 55m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 10m	4:00 PM	San Francisco	Bus Station Transbay	2:10 PM	San Diego	Old Town Transit Center	Economy	$66	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/10/2025 4:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 22h 10m
Greyhound US	21h 40m	4:00 PM	San Francisco	Bus Station Transbay	1:40 PM	San Diego	La Jolla Village	Economy	$66	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/10/2025 4:00:00 PM to La Jolla Village, San Diego (USA) arriving at 12/11/2025 1:40:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 21h 40m
Greyhound US	17h 20m	6:30 AM	San Francisco	Bus Station Transbay	11:50 PM	San Diego	Old Town Transit Center	Economy	$67	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/10/2025 6:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/10/2025 11:50:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 17h 20m
FlixBus	13h 55m	8:20 AM	San Francisco	5th/Townsend	10:15 PM	San Diego	Seaport Village	Economy	$83	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/10/2025 8:20:00 AM to Seaport Village, San Diego (USA) arriving at 12/10/2025 10:15:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 13h 55m
FlixBus	15h 30m	8:20 AM	San Francisco	5th/Townsend	11:50 PM	San Diego	Old Town Transit Center	Economy	$83	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/10/2025 8:20:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/10/2025 11:50:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 30m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	17h 55m	6:30 AM	San Francisco	Bus Station Transbay	12:25 AM	San Diego	San Ysidro Transit Center	Economy	$111	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/11/2025 6:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/12/2025 12:25:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 17h 55m
FlixBus	14h 25m	8:20 AM	San Francisco	5th/Townsend	10:45 PM	San Diego	San Ysidro Transit Center	Economy	$112	A Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 12/11/2025 8:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/11/2025 10:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 14h 25m
Greyhound US	13h 40m	10:40 PM	San Francisco	Bus Station Transbay	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$133	A Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 12/11/2025 10:40:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/12/2025 12:20:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 13h 40m

Did you know that if you travel from San Francisco to San Diego via Oakland, you can save more than $1? You will find the corresponding connections below.
- FlixBus
  
  Save more than 1%
  
  15h 5m
  
  San Francisco
  
  7 mi
  
  7:40 AM
  
  Oakland
  W Oakland BART Station
  
  10:45 PM
  
  San Diego
  San Ysidro Transit Center
  
  0 mi
  
  Economy
  
  $110
  
  A Bus from FlixBus goes from W Oakland BART Station, Oakland (USA) at 12/11/2025 7:40:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/11/2025 10:45:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 15h 5m
Did you know that if you travel from San Francisco to San Diego via Los Angeles, you can save more than $46? You can find the corresponding connections below.
- Busbud
  
  15h 30m
  
  0
  
  10:40 PM
  
  San Francisco
  Salesforce Transit Center
  
  7:55 AM
  
  Los Angeles
  Union Station
  
  0
  
  Economy
  
  $44
  
  A Bus from Busbud goes from Salesforce Transit Center, San Francisco (USA) at 12/7/2025 10:40:00 PM to Union Station, Los Angeles (USA) arriving at 12/8/2025 7:55:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 9h 15m
- Busbud
  
  3h 15m
  
  0
  
  10:55 AM
  
  Los Angeles
  Union Station
  
  2:10 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $21
  
  A Bus from Busbud goes from Union Station, Los Angeles (USA) at 12/8/2025 10:55:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 2:10:00 PM. 50 Economy ticket for $21 per person are available. Travel duration is 3h 15m
Travel time is 1h 50m longer, but you will save $46

Best Price Offer: The price for the cheapest bus from San Francisco to San Diego is $53 on 12/8/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between San Francisco and San Diego

See here how frequent the connections between San Francisco and San Diego are, during different times and days of the week.

Monday is the busiest day, with more than 15 daily buses from San Francisco to San Diego. Thursday has instead the fewest connections, with only 3 daily coaches between San Francisco and San Diego.

The busiest time of the day is the Morning, with 19 buses from San Francisco to San Diego, while Afternoon sees the fewest connections between San Francisco and San Diego, with 4 offers.

Facts about the bus from San Francisco to San Diego

Compare all providers like Greyhound US and FlixBus that travel 8 times every day by bus from San Francisco to San Diego in one click! Book your bus ticket from San Francisco to San Diego starting from $53!

Cheapest Bus	$53
Fastest Bus	12h 20m
Earliest Bus	6:30 AM
Latest Bus	10:40 PM
Daily Bus Routes	8 Ø
Distance	457.7 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from San Francisco to San Diego

Every day, 8 buses from 2 bus companies leave San Francisco for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

$67

Sunday 12/07

Monday 12/08

$65

Tuesday 12/09

Wednesday 12/10

$66

Thursday 12/11

$111

Friday 12/12

Saturday 12/13

$99

Sunday 12/14

$74

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

$59

Saturday 12/20

$84

Sunday 12/21

Monday 12/22

$66

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

$70

Saturday 12/27

The cheapest time to travel from San Francisco to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to San Diego, for the next 30 days.

With a price starting from $53, Monday is the cheapest day for a bus from San Francisco to San Diego. Thursday instead is the most expensive day with prices starting from $111.

Evening is the cheapest day time for bus tickets from San Francisco to San Diego, with $53. Afternoon is the most expensive time of the day with prices starting from $66.

How to save money travelling from San Francisco to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to San Diego are also emptier.

Beloved bus companies from San Francisco to San Diego

These are the most booked bus companies between San Francisco to San Diego from our users.

Greyhound US from San Francisco to San Diego

Here you will find the key facts about the Greyhound US bus route San Francisco to San Diego:

Cheapest Price	$56
Fastest Bus	13h 5m
Earliest Bus	6:30 AM
Last Bus	10:40 PM
Daily Connections	5 Ø
Found on	12/3/2025

FlixBus from San Francisco to San Diego

Here you will find the key facts about the FlixBus bus route San Francisco to San Diego:

Cheapest Price	$53
Fastest Bus	12h 20m
Earliest Bus	8:20 AM
Last Bus	8:20 AM
Daily Connections	4 Ø
Found on	12/3/2025

All bus stations and stops in San Francisco and San Diego

In the map below, you can see where to find all bus stations in San Francisco and San Diego.

5th/Townsend

Townsend St 400

Bus Station Transbay

Folsom Street 200

South Van Ness Ave & Market St

Beach St & Hyde St

Union Square

Post St 470

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Francisco to San Diego? Compare all modes of transports from San Francisco to San Diego.

Service and Comfort on the bus from San Francisco to San Diego

Want to know which seat classes are available on the buses from San Francisco to San Diego? Or which bus companies serve the route San Francisco to San Diego? Below you will find answers to your questions.

FAQs about the San Francisco to San Diego bus

How much does a San Francisco San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $53 and takes 17h 0m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Francisco to San Diego?

This route is offered by 2 companies with a range of ticket prices between $53 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Francisco to San Diego each day?

Every day, the San Francisco to San Diego bus route is served by approximately 8 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to San Diego take?

The fastest bus from San Francisco to San Diego is offered by FlixBus and takes 12h 20m. Bus tickets for this connection cost $54. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to San Diego?

The earliest bus arriving in San Diego from San Francisco starts at 6:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to San Diego?

The latest bus trip departing from San Francisco for San Diego starts at 10:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco San Diego route?

When traveling by bus from San Francisco to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and San Diego?

You can check all the direct connections between San Francisco and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to San Diego on your planned travel date.

Available seat classes which are offered on the bus route San Francisco to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to San Diego

Here’s an overview of the most popular bus routes to San Francisco and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!