Bus from San Francisco to San Diego from $74

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Compare all timetables for the bus from San Francisco to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Francisco to San Diego from various bus operators like Greyhound US or FlixBus for the next days.

today
$74
tomorrow
Tuesday
$77
Wednesday
$100
Thursday
Friday
$125
Saturday
$109

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 10m 4:00 PM San Francisco Bus Station Transbay 2:10 PM San Diego Old Town Transit Center  Economy $74
Greyhound US 21h 40m 4:00 PM San Francisco Bus Station Transbay 1:40 PM San Diego La Jolla Village  Economy $74
Greyhound US 17h 20m 6:30 AM San Francisco Bus Station Transbay 11:50 PM San Diego Old Town Transit Center  Economy $75
Greyhound US 17h 55m 6:30 AM San Francisco Bus Station Transbay 12:25 AM San Diego San Ysidro Transit Center  Economy $82
Greyhound US 13h 5m 10:40 PM San Francisco Bus Station Transbay 11:45 AM San Diego Old Town Transit Center  Economy $169
  • Did you know that if you travel from San Francisco to San Diego via Los Angeles, you can save more than $12? You can find the corresponding connections below.
    • Busbud
      18h 25m
      0
      10:00 PM
      San Francisco
      5th/Townsend
      5:05 AM
      Los Angeles
      University of California (curbside)
      0
      Busbud
      Economy
      $41
      • Waiting Time 7h 20m
    • Busbud
      4h 0m
      0
      12:25 PM
      Los Angeles
      Union Station
      4:25 PM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $21
    Travel time is 5h 20m longer, but you will save $12

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 13h 40m 10:40 PM San Francisco Bus Station Transbay 12:20 PM San Diego San Ysidro Transit Center  Economy $77
FlixBus 14h 25m 8:20 AM San Francisco 5th/Townsend 10:45 PM San Diego San Ysidro Transit Center  Economy $93
Greyhound US 17h 55m 6:30 AM San Francisco Bus Station Transbay 12:25 AM San Diego San Ysidro Transit Center  Economy $97
  • Did you know that if you travel from San Francisco to San Diego via Los Angeles, you can save more than $18? You can find the corresponding connections below.
    • Busbud
      19h 45m
      0
      4:00 PM
      San Francisco
      Salesforce Transit Center
      7:10 AM
      Los Angeles
      North Hollywood
      0
      Busbud
      Economy
      $36
      • Waiting Time 1h 10m
    • Busbud
      3h 25m
      0
      8:20 AM
      Los Angeles
      Union Station
      11:45 AM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $23
    Travel time is 6h 5m longer, but you will save $18

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 17h 55m 6:30 AM San Francisco Bus Station Transbay 12:25 AM San Diego San Ysidro Transit Center  Economy $100
FlixBus 14h 25m 8:20 AM San Francisco 5th/Townsend 10:45 PM San Diego San Ysidro Transit Center  Economy $118
Greyhound US 13h 40m 10:40 PM San Francisco Bus Station Transbay 12:20 PM San Diego San Ysidro Transit Center  Economy $122
  • Did you know that if you travel from San Francisco to San Diego via Los Angeles, you can save more than $41? You can find the corresponding connections below.
    • Busbud
      19h 45m
      0
      4:00 PM
      San Francisco
      Salesforce Transit Center
      7:10 AM
      Los Angeles
      North Hollywood
      0
      Busbud
      Economy
      $36
      • Waiting Time 1h 10m
    • Busbud
      3h 25m
      0
      8:20 AM
      Los Angeles
      Union Station
      11:45 AM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $23
    Travel time is 6h 5m longer, but you will save $41

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 17h 55m 6:30 AM San Francisco Bus Station Transbay 12:25 AM San Diego San Ysidro Transit Center  Economy $125
Greyhound US 13h 40m 10:40 PM San Francisco Bus Station Transbay 12:20 PM San Diego San Ysidro Transit Center  Economy $142
  • Did you know that if you travel from San Francisco to San Diego via Los Angeles, you can save more than $66? You can find the corresponding connections below.
    • Busbud
      19h 45m
      0
      4:00 PM
      San Francisco
      Salesforce Transit Center
      7:10 AM
      Los Angeles
      North Hollywood
      0
      Busbud
      Economy
      $36
      • Waiting Time 1h 10m
    • Busbud
      3h 25m
      0
      8:20 AM
      Los Angeles
      Union Station
      11:45 AM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $23
    Travel time is 6h 5m longer, but you will save $66

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 13h 40m 10:40 PM San Francisco Bus Station Transbay 12:20 PM San Diego San Ysidro Transit Center  Economy $109
Greyhound US 17h 55m 6:30 AM San Francisco Bus Station Transbay 12:25 AM San Diego San Ysidro Transit Center  Economy $113
Greyhound US 25h 50m 4:00 PM San Francisco Bus Station Transbay 5:50 PM San Diego San Ysidro Transit Center  Economy $113
  • Did you know that if you travel from San Francisco to San Diego via Los Angeles, you can save more than $50? You can find the corresponding connections below.
    • Busbud
      19h 45m
      0
      4:00 PM
      San Francisco
      Salesforce Transit Center
      7:10 AM
      Los Angeles
      North Hollywood
      0
      Busbud
      Economy
      $36
      • Waiting Time 1h 10m
    • Busbud
      3h 25m
      0
      8:20 AM
      Los Angeles
      Union Station
      11:45 AM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $23
    Travel time is 6h 5m longer, but you will save $50

Best Price Offer: The price for the cheapest bus from San Francisco to San Diego is $74 on 2/8/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between San Francisco and San Diego

See here how frequent the connections between San Francisco and San Diego are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from San Francisco to San Diego. Friday has instead the fewest connections, with only 2 daily coaches between San Francisco and San Diego.
The busiest time of the day is the Morning, with 8 buses from San Francisco to San Diego, while Afternoon sees the fewest connections between San Francisco and San Diego, with 3 offers.

Facts about the bus from San Francisco to San Diego

Compare all providers like Greyhound US and FlixBus that travel 3 times every day by bus from San Francisco to San Diego in one click! Book your bus ticket from San Francisco to San Diego starting from $74!

Cheapest Bus $74
Fastest Bus 13h 5m
Earliest Bus 6:30 AM
Latest Bus 10:40 PM
Daily Bus Routes 3 Ø
Distance 457.7 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from San Francisco to San Diego

Every day, 3 buses from 2 bus companies leave San Francisco for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/08/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/08
$82
Monday 02/09
Tuesday 02/10
$77
Wednesday 02/11
$100
Thursday 02/12
Friday 02/13
$125
Saturday 02/14
$109
Sunday 02/15
Monday 02/16
$87
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28
Sunday 03/01
Monday 03/02
Tuesday 03/03
Wednesday 03/04
Thursday 03/05
Friday 03/06
Saturday 03/07

The cheapest time to travel from San Francisco to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to San Diego, for the next 30 days.
With a price starting from $74, Sunday is the cheapest day for a bus from San Francisco to San Diego. Friday instead is the most expensive day with prices starting from $125.
Afternoon is the cheapest day time for bus tickets from San Francisco to San Diego, with $74. Evening is the most expensive time of the day with prices starting from $77.

How to save money travelling from San Francisco to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to San Diego are also emptier.

Beloved bus companies from San Francisco to San Diego

These are the most booked bus companies between San Francisco to San Diego from our users.

Greyhound US from San Francisco to San Diego

Greyhound US

Here you will find the key facts about the Greyhound US bus route San Francisco to San Diego:

Cheapest Price $74
Fastest Bus 13h 5m
Earliest Bus 6:30 AM
Last Bus 10:40 PM
Daily Connections 3 Ø
Found on 2/6/2026

FlixBus from San Francisco to San Diego

FlixBus

Here you will find the key facts about the FlixBus bus route San Francisco to San Diego:

Cheapest Price $93
Fastest Bus 14h 25m
Earliest Bus 8:20 AM
Last Bus 8:20 AM
Daily Connections 1 Ø
Found on 2/3/2026

All bus stations and stops in San Francisco and San Diego

In the map below, you can see where to find all bus stations in San Francisco and San Diego.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Francisco to San Diego? Compare all modes of transports from San Francisco to San Diego.

Service and Comfort on the bus from San Francisco to San Diego

Want to know which seat classes are available on the buses from San Francisco to San Diego? Or which bus companies serve the route San Francisco to San Diego? Below you will find answers to your questions.

FAQs about the San Francisco to San Diego bus

How much does a San Francisco San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 22h 10m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Francisco to San Diego?

This route is offered by 2 companies with a range of ticket prices between $74 and $169. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Francisco to San Diego each day?

Every day, the San Francisco to San Diego bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to San Diego take?

The fastest bus from San Francisco to San Diego is offered by Greyhound US and takes 13h 5m. Bus tickets for this connection cost $169. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to San Diego?

The earliest bus arriving in San Diego from San Francisco starts at 6:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to San Diego?

The latest bus trip departing from San Francisco for San Diego starts at 10:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco San Diego route?

When traveling by bus from San Francisco to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and San Diego?

You can check all the direct connections between San Francisco and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from San Francisco to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between San Francisco and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Francisco to San Diego?

Prices and availability for 3 trips between San Francisco and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Francisco to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to San Diego

Here’s an overview of the most popular bus routes to San Francisco and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Lodi, CA - San Francisco Bus Lodi, CA - San Francisco
From Redding, CA to San Francisco bus From Redding, CA to San Francisco bus
Bus from Cambridge, MA to San Francisco Bus from Cambridge, MA to San Francisco
From Glendale, CA to San Francisco bus From Glendale, CA to San Francisco bus
Bus Cedar City, UT to San Diego Bus Cedar City, UT to San Diego
Providence, RI to San Diego bus Providence, RI to San Diego bus
Buses Fontana, CA - San Diego Buses Fontana, CA - San Diego
Buses to San Diego from Downey, CA Buses to San Diego from Downey, CA
Popular Airport Shuttles to San Francisco and to San Diego
CheckMyBus › Buses in USA › Bus to San Francisco › Bus to San Diego

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