Bus Houston to San Diego - Compare all Companies

Compare all timetables for the bus from Houston to San Diego

Here is a selection of the cheapest bus trips from the schedule from Houston to San Diego from various bus operators like FlixBus or Greyhound US for the next days.

today

$160

tomorrow

Sunday

Monday

$181

Tuesday

Wednesday

$160

Thursday

$186

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	38h 40m	2:00 AM	Houston	Harrisburg Blvd Station	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$160	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/5/2025 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/6/2025 2:40:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 38h 40m
Greyhound US	38h 10m	2:00 AM	Houston	Harrisburg Blvd Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$163	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/5/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/6/2025 2:10:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 38h 10m
Greyhound US	37h 40m	2:00 AM	Houston	Harrisburg Blvd Station	1:40 PM	San Diego	La Jolla Village	Economy	$163	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/5/2025 2:00:00 AM to La Jolla Village, San Diego (USA) arriving at 12/6/2025 1:40:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 37h 40m
FlixBus	48h 30m	7:50 PM	Houston	Uptown/Upper Kirby	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$177	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/5/2025 7:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/7/2025 6:20:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 48h 30m
FlixBus	48h 45m	7:35 PM	Houston	Downtown Houston	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$178	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/5/2025 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/7/2025 6:20:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 48h 45m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	48h 55m	7:50 PM	Houston	Uptown/Upper Kirby	6:45 PM	San Diego	San Ysidro Transit Center	Economy	$181	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 7:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/10/2025 6:45:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 48h 55m
FlixBus	49h 10m	7:35 PM	Houston	Downtown Houston	6:45 PM	San Diego	San Ysidro Transit Center	Economy	$181	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/8/2025 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/10/2025 6:45:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 49h 10m
FlixBus	44h 45m	5:35 PM	Houston	Uptown/Upper Kirby	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$182	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 5:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/10/2025 12:20:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 44h 45m
Greyhound US	43h 20m	7:00 PM	Houston	Harrisburg Blvd Station	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$182	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 7:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/10/2025 12:20:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 43h 20m
Greyhound US	36h 0m	8:20 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$188	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 8:20:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/9/2025 6:20:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 36h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	38h 10m	2:00 AM	Houston	Harrisburg Blvd Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$160	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/10/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 38h 10m
Greyhound US	37h 40m	2:00 AM	Houston	Harrisburg Blvd Station	1:40 PM	San Diego	La Jolla Village	Economy	$161	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/10/2025 2:00:00 AM to La Jolla Village, San Diego (USA) arriving at 12/11/2025 1:40:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 37h 40m
Greyhound US	39h 30m	8:15 AM	Houston	Harrisburg Blvd Station	9:45 PM	San Diego	La Jolla Village	Economy	$168	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/10/2025 8:15:00 AM to La Jolla Village, San Diego (USA) arriving at 12/11/2025 9:45:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 39h 30m
FlixBus	53h 0m	11:10 AM	Houston	Downtown Houston	2:10 PM	San Diego	Old Town Transit Center	Economy	$171	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/10/2025 11:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/12/2025 2:10:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 53h 0m
FlixBus	50h 35m	11:10 AM	Houston	Downtown Houston	11:45 AM	San Diego	Old Town Transit Center	Economy	$171	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/10/2025 11:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/12/2025 11:45:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 50h 35m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	35h 30m	8:15 AM	Houston	Harrisburg Blvd Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$186	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/11/2025 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/12/2025 5:45:00 PM. 50 Economy ticket for $186 per person are available. Travel duration is 35h 30m
Greyhound US	40h 0m	8:15 AM	Houston	Harrisburg Blvd Station	10:15 PM	San Diego	Seaport Village	Economy	$186	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/11/2025 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 12/12/2025 10:15:00 PM. 50 Economy ticket for $186 per person are available. Travel duration is 40h 0m
Greyhound US	45h 15m	6:55 PM	Houston	Harrisburg Blvd Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$188	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/11/2025 6:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 2:10:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 45h 15m
FlixBus	57h 35m	6:35 AM	Houston	SW Agencia Autobuses	2:10 PM	San Diego	Old Town Transit Center	Economy	$188	A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/11/2025 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 2:10:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 57h 35m
FlixBus	55h 10m	6:35 AM	Houston	SW Agencia Autobuses	11:45 AM	San Diego	Old Town Transit Center	Economy	$188	A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/11/2025 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 11:45:00 AM. 50 Economy ticket for $188 per person are available. Travel duration is 55h 10m

Best Price Offer: The price for the cheapest bus from Houston to San Diego is $152 on 12/3/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and San Diego

See here how frequent the connections between Houston and San Diego are, during different times and days of the week.

Friday is the busiest day, with more than 37 daily buses from Houston to San Diego. Monday has instead the fewest connections, with only 7 daily coaches between Houston and San Diego.

The busiest time of the day is the Morning, with 35 buses from Houston to San Diego, while Night sees the fewest connections between Houston and San Diego, with 8 offers.

Facts about the bus from Houston to San Diego

Compare all providers like FlixBus and Greyhound US that travel 23 times every day by bus from Houston to San Diego in one click! Book your bus ticket from Houston to San Diego starting from $152!

Cheapest Bus	$152
Fastest Bus	33h 25m
Earliest Bus	2:00 AM
Latest Bus	6:55 PM
Daily Bus Routes	23 Ø
Distance	1,301.0 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Houston to San Diego

Every day, 23 buses from 2 bus companies leave Houston for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$160

Saturday 12/06

Sunday 12/07

Monday 12/08

$181

Tuesday 12/09

Wednesday 12/10

$160

Thursday 12/11

$189

Friday 12/12

Saturday 12/13

$181

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Houston to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to San Diego, for the next 30 days.

With a price starting from $160, Friday is the cheapest day for a bus from Houston to San Diego. Thursday instead is the most expensive day with prices starting from $186.

Night is the cheapest day time for bus tickets from Houston to San Diego, with $160. Afternoon is the most expensive time of the day with prices starting from $182.

How to save money travelling from Houston to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to San Diego are also emptier.

Beloved bus companies from Houston to San Diego

These are the most booked bus companies between Houston to San Diego from our users.

Greyhound US from Houston to San Diego

Here you will find the key facts about the Greyhound US bus route Houston to San Diego:

Cheapest Price	$160
Fastest Bus	33h 25m
Earliest Bus	2:00 AM
Last Bus	6:55 PM
Daily Connections	8 Ø
Found on	12/3/2025

All bus stations and stops in Houston and San Diego

In the map below, you can see where to find all bus stations in Houston and San Diego.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Uptown/Upper Kirby

Southwest Fwy 2525

Chase Bank

Milam Street 212

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Houston to San Diego? Compare all modes of transports from Houston to San Diego.

Service and Comfort on the bus from Houston to San Diego

Want to know which seat classes are available on the buses from Houston to San Diego? Or which bus companies serve the route Houston to San Diego? Below you will find answers to your questions.

FAQs about the Houston to San Diego bus

How much does a Houston San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $152 and takes 36h 40m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Houston to San Diego?

This route is offered by 2 companies with a range of ticket prices between $152 and $234. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Houston to San Diego each day?

Every day, the Houston to San Diego bus route is served by approximately 23 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to San Diego take?

The fastest bus from Houston to San Diego is offered by Greyhound US and takes 33h 25m. Bus tickets for this connection cost $173. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to San Diego?

The earliest bus arriving in San Diego from Houston starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to San Diego?

The latest bus trip departing from Houston for San Diego starts at 6:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston San Diego route?

When traveling by bus from Houston to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and San Diego?

You can check all the direct connections between Houston and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Houston to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Houston to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to San Diego

Here’s an overview of the most popular bus routes to Houston and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!