Bus from Houston to San Diego from $133

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Compare all timetables for the bus from Houston to San Diego

Here is a selection of the cheapest bus trips from the schedule from Houston to San Diego from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.
today
from $348
tomorrow
from $221
Thursday
Friday
from $174
Saturday
from $133
Sunday
Monday
from $221

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    39h 20m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    5:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $348
  • Greyhound US
    43h 30m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $363
  • FlixBus
    50h 15m
    0
    3:05 PM
    Houston
    SW Agencia Autobuses
    5:20 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $384
  • FlixBus
    40h 5m
    0
    6:00 PM
    Houston
    Downtown Houston
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $390
  • Greyhound Lines Mexico
    48h 0m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $396
  • Did you know that if you travel from Houston to San Diego via El Paso, TX, you can save more than $180? You can find the corresponding connections below.
    • Busbud
      45h 50m
      0
      2:00 AM
      Houston
      Harrisburg Blvd Station
      3:35 PM
      El Paso, TX
      Bus Station
      0
      Busbud
      Economy
      $92
      • Waiting Time 10h 45m
    • Busbud
      21h 30m
      0
      2:20 AM
      El Paso, TX
      Bus Station
      11:50 PM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $75
    Travel time is 6h 30m longer, but you will save $180

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound Lines Mexico
    48h 0m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $221
  • FlixBus
    46h 55m
    0
    11:10 AM
    Houston
    Downtown Houston
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $221
  • FlixBus
    46h 40m
    0
    11:25 AM
    Houston
    Uptown/Upper Kirby
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $221
  • Greyhound US
    39h 5m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $222
  • Greyhound US
    40h 5m
    0
    8:20 AM
    Houston
    Harrisburg Blvd Station
    12:25 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $229
  • Did you know that if you travel from Houston to San Diego via El Paso, TX, you can save more than $64? You can find the corresponding connections below.
    • Busbud
      39h 45m
      0
      2:00 AM
      Houston
      Harrisburg Blvd Station
      3:35 PM
      El Paso, TX
      Bus Station
      0
      Busbud
      Economy
      $81
      • Waiting Time 10h 45m
    • Busbud
      15h 25m
      0
      2:20 AM
      El Paso, TX
      Bus Station
      5:45 PM
      San Diego
      Old Town Transit Center
      0
      Busbud
      Economy
      $76
    Travel time is 0h 40m longer, but you will save $64

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    37h 45m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    8:45 AM
    San Diego
    La Jolla Village
    0
    Greyhound US
    Economy
    $174
  • Greyhound Lines Mexico
    47h 25m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $174
  • FlixBus
    41h 5m
    0
    5:35 PM
    Houston
    Uptown/Upper Kirby
    10:40 AM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $174
  • Greyhound Lines Mexico
    47h 10m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $175
  • FlixBus
    39h 10m
    0
    5:35 PM
    Houston
    Uptown/Upper Kirby
    8:45 AM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $175
  • Did you know that if you travel from Houston to San Diego via El Paso, TX, you can save more than $21? You can find the corresponding connections below.
    • Busbud
      48h 15m
      0
      2:00 AM
      Houston
      Harrisburg Blvd Station
      3:35 PM
      El Paso, TX
      Bus Station
      0
      Busbud
      Economy
      $80
      • Waiting Time 15h 25m
    • FlixBus
      19h 15m
      0
      7:00 AM
      El Paso, TX
      Bus Station
      2:15 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $73
    Travel time is 10h 30m longer, but you will save $21

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    38h 10m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    4:10 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $133
  • Greyhound US
    37h 20m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    3:20 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $140
  • FlixBus
    40h 5m
    0
    6:00 PM
    Houston
    Downtown Houston
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $145
  • Greyhound Lines Mexico
    48h 0m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $146
  • FlixBus
    40h 30m
    0
    5:35 PM
    Houston
    Uptown/Upper Kirby
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $146

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    34h 0m
    0
    8:20 AM
    Houston
    Harrisburg Blvd Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $221
  • FlixBus
    46h 55m
    0
    7:50 PM
    Houston
    Uptown/Upper Kirby
    6:45 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $226
  • FlixBus
    47h 10m
    0
    7:35 PM
    Houston
    Downtown Houston
    6:45 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $226
  • Greyhound US
    39h 5m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $230
  • Greyhound Lines Mexico
    48h 0m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $232
  • Did you know that if you travel from Houston to San Diego via El Paso, TX, you can save more than $68? You can find the corresponding connections below.
    • Busbud
      48h 15m
      0
      2:00 AM
      Houston
      Harrisburg Blvd Station
      3:35 PM
      El Paso, TX
      Bus Station
      0
      Busbud
      Economy
      $80
      • Waiting Time 15h 25m
    • FlixBus
      19h 15m
      0
      7:00 AM
      El Paso, TX
      Bus Station
      2:15 AM
      San Diego
      San Ysidro Transit Center
      0
      FlixBus
      Economy
      $73
    Travel time is 14h 15m longer, but you will save $68

Frequency of bus connections between Houston and San Diego

See here how frequent the connections between Houston and San Diego are, during different times and days of the week.
Tuesday is the busiest day, with more than 66 daily buses from Houston to San Diego. Wednesday has instead the fewest connections, with only 30 daily coaches between Houston and San Diego.
The busiest time of the day is the Evening, with 100 buses from Houston to San Diego, while Night sees the fewest connections between Houston and San Diego, with 23 offers.

Facts about the bus from Houston to San Diego

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 41 times every day by bus from Houston to San Diego in one click! Book your bus ticket from Houston to San Diego starting from $133!

Cheapest Bus $133
Fastest Bus 33h 25m
Earliest Bus 2:00 AM
Latest Bus 7:50 PM
Daily Bus Routes 41 Ø
Distance 1,301.0 miles
Bus Companies FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from Houston to San Diego

Every day, 41 buses from 3 bus companies leave Houston for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/17/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
$348
Wednesday 06/18
$250
Thursday 06/19
Friday 06/20
$379
Saturday 06/21
$140
Sunday 06/22
Monday 06/23
$221
Tuesday 06/24
$221
Wednesday 06/25
Thursday 06/26
$286
Friday 06/27
Saturday 06/28
Sunday 06/29
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
Friday 07/04
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12

The cheapest time to travel from Houston to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to San Diego, for the next 30 days.
With a price starting from $133, Saturday is the cheapest day for a bus from Houston to San Diego. Tuesday instead is the most expensive day with prices starting from $348.
Night is the cheapest day time for bus tickets from Houston to San Diego, with $133. Afternoon is the most expensive time of the day with prices starting from $146.

How to save money travelling from Houston to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to San Diego are also emptier.

Beloved bus companies from Houston to San Diego

These are the most booked bus companies between Houston to San Diego from our users.

Greyhound US from Houston to San Diego

Greyhound US

Here you will find the key facts about the Greyhound US bus route Houston to San Diego:

Cheapest Price $133
Fastest Bus 33h 25m
Earliest Bus 2:00 AM
Last Bus 7:00 PM
Daily Connections 13 Ø
Found on 6/14/2025

All bus stations and stops in Houston and San Diego

In the map below, you can see where to find all bus stations in Houston and San Diego.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Houston to San Diego? Compare all modes of transports from Houston to San Diego.

Service and Comfort on the bus from Houston to San Diego

Want to know which seat classes are available on the buses from Houston to San Diego? Or which bus companies serve the route Houston to San Diego? Below you will find answers to your questions.

FAQs about the Houston to San Diego bus

How much does a Houston San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $133 and takes 38h 10m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Houston to San Diego?

This route is offered by 3 companies with a range of ticket prices between $133 and $438. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Houston to San Diego each day?

Every day, the Houston to San Diego bus route is served by approximately 41 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to San Diego take?

The fastest bus from Houston to San Diego is offered by Greyhound US and takes 33h 25m. Bus tickets for this connection cost $180. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to San Diego?

The earliest bus arriving in San Diego from Houston starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to San Diego?

The latest bus trip departing from Houston for San Diego starts at 7:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston San Diego route?

When traveling by bus from Houston to San Diego, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and San Diego?

You can check all the direct connections between Houston and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Houston to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to San Diego

Here’s an overview of the most popular bus routes to Houston and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Houston and to San Diego
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