Bus Houston to San Diego - Compare all Companies

Compare all timetables for the bus from Houston to San Diego

Here is a selection of the cheapest bus trips from the schedule from Houston to San Diego from various bus operators like FlixBus, Greyhound US or Valley Transit for the next days.

today

tomorrow

$129

Saturday

$123

Sunday

$110

Monday

$112

Tuesday

$123

Wednesday

$129

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 20m	2:00 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$129	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/8/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/9/2026 6:20:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 42h 20m
Greyhound US	49h 25m	6:55 PM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$129	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/8/2026 6:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/10/2026 6:20:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 49h 25m
Valley Transit	61h 45m	6:35 AM	Houston	SW Agencia Autobuses	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$130	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/8/2026 6:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/10/2026 6:20:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 61h 45m
FlixBus	48h 45m	7:35 PM	Houston	Downtown Houston	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$130	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/8/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/10/2026 6:20:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 48h 45m
FlixBus	50h 45m	5:35 PM	Houston	Uptown/Upper Kirby	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$131	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/8/2026 5:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/10/2026 6:20:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 50h 45m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 20m	2:00 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$123	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/9/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/10/2026 6:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 42h 20m
Greyhound US	36h 5m	8:15 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$123	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/9/2026 8:15:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/10/2026 6:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 36h 5m
FlixBus	48h 30m	7:50 PM	Houston	Uptown/Upper Kirby	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$125	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/9/2026 7:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/11/2026 6:20:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 48h 30m
Valley Transit	61h 45m	6:35 AM	Houston	SW Agencia Autobuses	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$126	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/9/2026 6:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/11/2026 6:20:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 61h 45m
FlixBus	50h 45m	5:35 PM	Houston	Uptown/Upper Kirby	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$126	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/9/2026 5:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/11/2026 6:20:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 50h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	36h 5m	8:15 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$110	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/10/2026 8:15:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/11/2026 6:20:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 36h 5m
Greyhound US	42h 20m	2:00 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$112	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/10/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/11/2026 6:20:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 42h 20m
FlixBus	48h 45m	7:35 PM	Houston	Downtown Houston	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$112	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/10/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/12/2026 6:20:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 48h 45m
FlixBus	48h 30m	7:50 PM	Houston	Uptown/Upper Kirby	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$114	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/10/2026 7:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/12/2026 6:20:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 48h 30m
Valley Transit	61h 45m	6:35 AM	Houston	SW Agencia Autobuses	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$121	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/10/2026 6:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/12/2026 6:20:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 61h 45m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 20m	2:00 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$112	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/11/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/12/2026 6:20:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 42h 20m
Greyhound US	41h 10m	2:00 AM	Houston	Harrisburg Blvd Station	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$115	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/11/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/12/2026 5:10:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 41h 10m
FlixBus	48h 55m	7:50 PM	Houston	Uptown/Upper Kirby	6:45 PM	San Diego	San Ysidro Transit Center	Economy	$116	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/11/2026 7:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/13/2026 6:45:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 48h 55m
FlixBus	49h 10m	7:35 PM	Houston	Downtown Houston	6:45 PM	San Diego	San Ysidro Transit Center	Economy	$116	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/11/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/13/2026 6:45:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 49h 10m
Valley Transit	55h 10m	6:35 AM	Houston	SW Agencia Autobuses	11:45 AM	San Diego	Old Town Transit Center	Economy	$145	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/11/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/13/2026 11:45:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 55h 10m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	61h 45m	6:35 AM	Houston	SW Agencia Autobuses	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$123	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/12/2026 6:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/14/2026 6:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 61h 45m
Greyhound US	40h 30m	8:15 AM	Houston	Harrisburg Blvd Station	10:45 PM	San Diego	San Ysidro Transit Center	Economy	$123	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/12/2026 8:15:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/13/2026 10:45:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 40h 30m
Greyhound US	43h 25m	6:55 PM	Houston	Harrisburg Blvd Station	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$123	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/12/2026 6:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/14/2026 12:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 43h 25m
FlixBus	50h 45m	5:35 PM	Houston	Uptown/Upper Kirby	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$123	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/12/2026 5:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/14/2026 6:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 50h 45m
FlixBus	50h 20m	6:00 PM	Houston	Downtown Houston	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$123	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/12/2026 6:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/14/2026 6:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 50h 20m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 20m	2:00 AM	Houston	Harrisburg Blvd Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$129	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/13/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/14/2026 6:20:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 42h 20m
Greyhound US	41h 10m	2:00 AM	Houston	Harrisburg Blvd Station	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$131	A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 5/13/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/14/2026 5:10:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 41h 10m
Valley Transit	61h 45m	6:35 AM	Houston	SW Agencia Autobuses	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$137	A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 5/13/2026 6:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/15/2026 6:20:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 61h 45m
FlixBus	57h 10m	11:10 AM	Houston	Downtown Houston	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$137	A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 5/13/2026 11:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/15/2026 6:20:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 57h 10m
FlixBus	56h 55m	11:25 AM	Houston	Uptown/Upper Kirby	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$137	A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 5/13/2026 11:25:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 5/15/2026 6:20:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 56h 55m

Best Price Offer: The price for the cheapest bus from Houston to San Diego is $110 on 5/10/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Houston and San Diego

See here how frequent the connections between Houston and San Diego are, during different times and days of the week.

Saturday is the busiest day, with more than 62 daily buses from Houston to San Diego. Sunday has instead the fewest connections, with only 36 daily coaches between Houston and San Diego.

The busiest time of the day is the Evening, with 138 buses from Houston to San Diego, while Afternoon sees the fewest connections between Houston and San Diego, with 32 offers.

Facts about the bus from Houston to San Diego

Compare all providers like FlixBus, Greyhound US and Valley Transit that travel 47 times every day by bus from Houston to San Diego in one click! Book your bus ticket from Houston to San Diego starting from $110!

Cheapest Bus	$110
Fastest Bus	33h 30m
Earliest Bus	2:00 AM
Latest Bus	6:55 PM
Daily Bus Routes	47 Ø
Distance	1,301.0 miles
Bus Companies	FlixBus, Greyhound US and Valley Transit

Cheapest bus connections from Houston to San Diego

Every day, 47 buses from 3 bus companies leave Houston for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$175

Saturday 05/09

$176

Sunday 05/10

$162

Monday 05/11

$140

Tuesday 05/12

$123

Wednesday 05/13

$165

Thursday 05/14

$123

Friday 05/15

$165

Saturday 05/16

$162

Sunday 05/17

$131

Monday 05/18

$118

Tuesday 05/19

$162

Wednesday 05/20

$171

Thursday 05/21

$160

Friday 05/22

$160

Saturday 05/23

$168

Sunday 05/24

$150

Monday 05/25

$123

Tuesday 05/26

$166

Wednesday 05/27

$163

Thursday 05/28

$148

Friday 05/29

$125

Saturday 05/30

The cheapest time to travel from Houston to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to San Diego, for the next 30 days.

With a price starting from $110, Sunday is the cheapest day for a bus from Houston to San Diego. Wednesday instead is the most expensive day with prices starting from $129.

Morning is the cheapest day time for bus tickets from Houston to San Diego, with $110. Afternoon is the most expensive time of the day with prices starting from $118.

How to save money travelling from Houston to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to San Diego are also emptier.

All bus stations and stops in Houston and San Diego

In the map below, you can see where to find all bus stations in Houston and San Diego.

Downtown Houston

Gray St 605

Harrisburg Blvd Station

Harrisburg Blvd 7000

Main Street

Main St 2121

Chase Bank

Milam Street 212

Uptown/Upper Kirby

Southwest Fwy 2525

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Houston to San Diego

Want to know which seat classes are available on the buses from Houston to San Diego? Or which bus companies serve the route Houston to San Diego? Below you will find answers to your questions.

FAQs about the Houston to San Diego bus

How much does a Houston San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 34h 5m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Houston to San Diego?

This route is offered by 3 companies with a range of ticket prices between $110 and $185. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Houston to San Diego each day?

Every day, the Houston to San Diego bus route is served by approximately 47 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to San Diego take?

The fastest bus from Houston to San Diego is offered by Greyhound US and takes 33h 30m. Bus tickets for this connection cost $176. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to San Diego?

The earliest bus arriving in San Diego from Houston starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to San Diego?

The latest bus trip departing from Houston for San Diego starts at 6:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston San Diego route?

When traveling by bus from Houston to San Diego, passengers can travel with FlixBus, Greyhound US and Valley Transit. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and San Diego?

You can check all the direct connections between Houston and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Valley Transit.

What can I take with me on the Houston to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 47 daily trips between Houston and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to San Diego?

Prices and availability for 47 trips between Houston and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to San Diego

Here’s an overview of the most popular bus routes to Houston and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!