Compare all timetables for the bus from Houston to San Diego
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $156 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/6/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/7/2026 4:25:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 40h 25m
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| Greyhound US | 35h 30m | 8:15 AM | Houston | Harrisburg Blvd Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $158 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/6/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/7/2026 5:45:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 35h 30m
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| FlixBus | 52h 0m | 2:25 PM | Houston | Downtown Houston | 4:25 PM | San Diego | Old Town Transit Center | Economy | $165 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/6/2026 2:25:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/8/2026 4:25:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 52h 0m
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| Valley Transit | 55h 10m | 6:35 AM | Houston | SW Agencia Autobuses | 11:45 AM | San Diego | Old Town Transit Center | Economy | $166 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/6/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/8/2026 11:45:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 55h 10m
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| FlixBus | 45h 40m | 2:25 PM | Houston | Downtown Houston | 10:05 AM | San Diego | Seaport Village | Economy | $166 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/6/2026 2:25:00 PM to Seaport Village, San Diego (USA) arriving at 8/8/2026 10:05:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 45h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $145 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/7/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/8/2026 4:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 40h 25m
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| Greyhound US | 40h 0m | 8:15 AM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $154 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/7/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 8/8/2026 10:15:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 40h 0m
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| FlixBus | 43h 45m | 6:00 PM | Houston | Downtown Houston | 11:45 AM | San Diego | Old Town Transit Center | Economy | $163 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/7/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/9/2026 11:45:00 AM. 50 Economy ticket for $163 per person are available. Travel duration is 43h 45m
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| Valley Transit | 55h 10m | 6:35 AM | Houston | SW Agencia Autobuses | 11:45 AM | San Diego | Old Town Transit Center | Economy | $164 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/7/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/9/2026 11:45:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 55h 10m
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| Valley Transit | 53h 30m | 6:35 AM | Houston | SW Agencia Autobuses | 10:05 AM | San Diego | Seaport Village | Economy | $164 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/7/2026 6:35:00 AM to Seaport Village, San Diego (USA) arriving at 8/9/2026 10:05:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 53h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $153 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/8/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/9/2026 4:25:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 40h 25m
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| Greyhound US | 42h 20m | 2:00 AM | Houston | Harrisburg Blvd Station | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $156 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/8/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 8/9/2026 6:20:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 42h 20m
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| Valley Transit | 55h 10m | 6:35 AM | Houston | SW Agencia Autobuses | 11:45 AM | San Diego | Old Town Transit Center | Economy | $161 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/8/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/10/2026 11:45:00 AM. 50 Economy ticket for $161 per person are available. Travel duration is 55h 10m
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| Valley Transit | 59h 50m | 6:35 AM | Houston | SW Agencia Autobuses | 4:25 PM | San Diego | Old Town Transit Center | Economy | $164 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/8/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/10/2026 4:25:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 59h 50m
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| FlixBus | 48h 25m | 6:00 PM | Houston | Downtown Houston | 4:25 PM | San Diego | Old Town Transit Center | Economy | $165 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/8/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/10/2026 4:25:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 48h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $145 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/9/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/10/2026 4:25:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 40h 25m
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| Greyhound US | 39h 55m | 2:00 AM | Houston | Harrisburg Blvd Station | 3:55 PM | San Diego | La Jolla Village | Economy | $145 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/9/2026 2:00:00 AM to La Jolla Village, San Diego (USA) arriving at 8/10/2026 3:55:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 39h 55m
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| Valley Transit | 61h 45m | 6:35 AM | Houston | SW Agencia Autobuses | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $164 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/9/2026 6:35:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 8/11/2026 6:20:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 61h 45m
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| FlixBus | 50h 20m | 6:00 PM | Houston | Downtown Houston | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $165 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/9/2026 6:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 8/11/2026 6:20:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 50h 20m
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| FlixBus | 47h 55m | 6:00 PM | Houston | Downtown Houston | 3:55 PM | San Diego | La Jolla Village | Economy | $165 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/9/2026 6:00:00 PM to La Jolla Village, San Diego (USA) arriving at 8/11/2026 3:55:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 47h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $160 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/10/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/11/2026 4:25:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 40h 25m
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| Greyhound US | 42h 20m | 2:00 AM | Houston | Harrisburg Blvd Station | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $163 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/10/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 8/11/2026 6:20:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 42h 20m
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| FlixBus | 52h 40m | 7:35 PM | Houston | Downtown Houston | 10:15 PM | San Diego | Seaport Village | Economy | $173 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/10/2026 7:35:00 PM to Seaport Village, San Diego (USA) arriving at 8/12/2026 10:15:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 52h 40m
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| FlixBus | 43h 45m | 6:00 PM | Houston | Downtown Houston | 11:45 AM | San Diego | Old Town Transit Center | Economy | $174 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/10/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/12/2026 11:45:00 AM. 50 Economy ticket for $174 per person are available. Travel duration is 43h 45m
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| Valley Transit | 55h 10m | 6:35 AM | Houston | SW Agencia Autobuses | 11:45 AM | San Diego | Old Town Transit Center | Economy | $175 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/10/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/12/2026 11:45:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 55h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 0m | 8:15 AM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $160 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/11/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 8/12/2026 10:15:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 40h 0m
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| Greyhound US | 35h 30m | 8:15 AM | Houston | Harrisburg Blvd Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $162 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/11/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/12/2026 5:45:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 35h 30m
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| FlixBus | 48h 35m | 7:35 PM | Houston | Downtown Houston | 6:10 PM | San Diego | Old Town Transit Center | Economy | $173 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/11/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/13/2026 6:10:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 48h 35m
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| FlixBus | 48h 25m | 6:00 PM | Houston | Downtown Houston | 4:25 PM | San Diego | Old Town Transit Center | Economy | $174 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/11/2026 6:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/13/2026 4:25:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 48h 25m
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| Valley Transit | 59h 50m | 6:35 AM | Houston | SW Agencia Autobuses | 4:25 PM | San Diego | Old Town Transit Center | Economy | $175 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/11/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/13/2026 4:25:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 59h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $167 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/12/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/13/2026 4:25:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 40h 25m
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| Greyhound US | 35h 30m | 8:15 AM | Houston | Harrisburg Blvd Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $169 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/12/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/13/2026 5:45:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 35h 30m
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| FlixBus | 50h 55m | 5:15 PM | Houston | Downtown Houston | 6:10 PM | San Diego | Old Town Transit Center | Economy | $173 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/12/2026 5:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/14/2026 6:10:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 50h 55m
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| FlixBus | 50h 30m | 5:15 PM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $174 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 8/12/2026 5:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/14/2026 5:45:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 50h 30m
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| Valley Transit | 55h 10m | 6:35 AM | Houston | SW Agencia Autobuses | 11:45 AM | San Diego | Old Town Transit Center | Economy | $175 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 8/12/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 8/14/2026 11:45:00 AM. 50 Economy ticket for $175 per person are available. Travel duration is 55h 10m
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Greyhound US35h 30m08:15 AMHoustonHarrisburg Blvd Station3:05 PMEl Centro, CABus Stop0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 8/13/2026 8:15:00 AM to Bus Stop, El Centro, CA (USA) arriving at 8/14/2026 3:05:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 32h 50m
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Greyhound US2h 30m03:15 PMEl Centro, CABus Stop5:45 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Bus Stop, El Centro, CA (USA) at 8/14/2026 3:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 8/14/2026 5:45:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 30m
Waiting Time 0h 10m -
Best Price Offer: The price for the cheapest bus from Houston to San Diego is $140 on 8/24/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Houston and San Diego
Facts about the bus from Houston to San Diego
Compare all providers like Greyhound US, FlixBus and Valley Transit that travel 25 times every day by bus from Houston to San Diego in one click! Book your bus ticket from Houston to San Diego starting from $140!
| Cheapest Bus | $140 |
| Fastest Bus | 33h 30m |
| Earliest Bus | 2:00 AM |
| Latest Bus | 6:55 PM |
| Daily Bus Routes | 25 Ø |
| Distance | 1,301.0 miles |
| Bus Companies | Greyhound US, FlixBus and Valley Transit |
Cheapest bus connections from Houston to San Diego
Every day, 25 buses from 3 bus companies leave Houston for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/06/2026 and for the following days.
The cheapest time to travel from Houston to San Diego
How to save money travelling from Houston to San Diego
Book the ticket from Houston to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to San Diego are also emptier.All bus stations and stops in Houston and San Diego
In the map below, you can see where to find all bus stations in Houston and San Diego.
Service and Comfort on the bus from Houston to San Diego
FAQs about the Houston to San Diego bus
How much does a Houston San Diego bus trip cost?
How much could I save by comparing buses from Houston to San Diego?
On average, how many connections are available from Houston to San Diego each day?
How long does a bus journey from Houston to San Diego take?
What time is the first bus from Houston to San Diego?
What time is the last bus from Houston to San Diego?
Which bus companies operate the Houston San Diego route?
Is there a direct bus between Houston and San Diego?
What can I take with me on the Houston to San Diego bus route?
What equipment is available for the Houston San Diego bus route?
How does CheckMyBus find the best bus deals from Houston to San Diego?
How does CheckMyBus technology work for trips from Houston to San Diego?
Available seat classes which are offered on the bus route Houston to San Diego
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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