Compare all timetables for the bus from Houston to San Diego
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 48h 10m | 7:35 PM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $152 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/3/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/5/2026 5:45:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 48h 10m
|
||
| FlixBus | 52h 40m | 7:35 PM | Houston | Downtown Houston | 10:15 PM | San Diego | Seaport Village | Economy | $152 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/3/2026 7:35:00 PM to Seaport Village, San Diego (USA) arriving at 11/5/2026 10:15:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 52h 40m
|
||
| FlixBus | 54h 40m | 5:35 PM | Houston | SW Agencia Autobuses | 10:15 PM | San Diego | Seaport Village | Economy | $160 |
A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 11/3/2026 5:35:00 PM to Seaport Village, San Diego (USA) arriving at 11/5/2026 10:15:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 54h 40m
|
||
| Greyhound US | 53h 20m | 6:55 PM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $162 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/3/2026 6:55:00 PM to Seaport Village, San Diego (USA) arriving at 11/5/2026 10:15:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 53h 20m
|
||
| Greyhound US | 42h 35m | 6:55 PM | Houston | Harrisburg Blvd Station | 11:30 AM | San Diego | Old Town Transit Center | Economy | $166 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/3/2026 6:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/5/2026 11:30:00 AM. 50 Economy ticket for $166 per person are available. Travel duration is 42h 35m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 35h 30m | 8:15 AM | Houston | Harrisburg Blvd Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $147 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/4/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/5/2026 5:45:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 35h 30m
|
||
| Greyhound US | 40h 0m | 8:15 AM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $148 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/4/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 11/5/2026 10:15:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 40h 0m
|
||
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $150 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/4/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/5/2026 4:25:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 40h 25m
|
||
| FlixBus | 50h 30m | 5:15 PM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $154 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/4/2026 5:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/6/2026 5:45:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 50h 30m
|
||
| FlixBus | 50h 10m | 5:35 PM | Houston | SW Agencia Autobuses | 5:45 PM | San Diego | Old Town Transit Center | Economy | $155 |
A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 11/4/2026 5:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/6/2026 5:45:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 50h 10m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 0m | 8:15 AM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $152 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/5/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 11/6/2026 10:15:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 40h 0m
|
||
| FlixBus | 42h 55m | 5:20 AM | Houston | Downtown Houston | 10:15 PM | San Diego | Seaport Village | Economy | $152 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/5/2026 5:20:00 AM to Seaport Village, San Diego (USA) arriving at 11/6/2026 10:15:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 42h 55m
|
||
| Greyhound US | 35h 30m | 8:15 AM | Houston | Harrisburg Blvd Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $154 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/5/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/6/2026 5:45:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 35h 30m
|
||
| FlixBus | 38h 25m | 5:20 AM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $154 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/5/2026 5:20:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/6/2026 5:45:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 38h 25m
|
||
| FlixBus | 50h 30m | 5:15 PM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $154 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/5/2026 5:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/7/2026 5:45:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 50h 30m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 0m | 8:15 AM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $130 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/6/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 11/7/2026 10:15:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 40h 0m
|
||
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $131 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/6/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/7/2026 4:25:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 40h 25m
|
||
| FlixBus | 48h 10m | 7:35 PM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $131 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/6/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/8/2026 5:45:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 48h 10m
|
||
| FlixBus | 52h 40m | 7:35 PM | Houston | Downtown Houston | 10:15 PM | San Diego | Seaport Village | Economy | $132 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/6/2026 7:35:00 PM to Seaport Village, San Diego (USA) arriving at 11/8/2026 10:15:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 52h 40m
|
||
| Valley Transit | 55h 10m | 6:35 AM | Houston | SW Agencia Autobuses | 11:45 AM | San Diego | Old Town Transit Center | Economy | $140 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 11/6/2026 6:35:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/8/2026 11:45:00 AM. 50 Economy ticket for $140 per person are available. Travel duration is 55h 10m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 52h 40m | 7:35 PM | Houston | Downtown Houston | 10:15 PM | San Diego | Seaport Village | Economy | $120 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/7/2026 7:35:00 PM to Seaport Village, San Diego (USA) arriving at 11/9/2026 10:15:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 52h 40m
|
||
| FlixBus | 48h 10m | 7:35 PM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $120 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/7/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/9/2026 5:45:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 48h 10m
|
||
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $122 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/7/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/8/2026 4:25:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 40h 25m
|
||
| Greyhound US | 42h 20m | 2:00 AM | Houston | Harrisburg Blvd Station | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $123 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/7/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/8/2026 6:20:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 42h 20m
|
||
| Greyhound US | 35h 30m | 8:15 AM | Houston | Harrisburg Blvd Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $123 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/7/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/8/2026 5:45:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 35h 30m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 40h 0m | 8:15 AM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $116 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/8/2026 8:15:00 AM to Seaport Village, San Diego (USA) arriving at 11/9/2026 10:15:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 40h 0m
|
||
| FlixBus | 42h 55m | 5:20 AM | Houston | Downtown Houston | 10:15 PM | San Diego | Seaport Village | Economy | $116 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/8/2026 5:20:00 AM to Seaport Village, San Diego (USA) arriving at 11/9/2026 10:15:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 42h 55m
|
||
| Greyhound US | 53h 20m | 6:55 PM | Houston | Harrisburg Blvd Station | 10:15 PM | San Diego | Seaport Village | Economy | $117 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/8/2026 6:55:00 PM to Seaport Village, San Diego (USA) arriving at 11/10/2026 10:15:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 53h 20m
|
||
| Greyhound US | 35h 30m | 8:15 AM | Houston | Harrisburg Blvd Station | 5:45 PM | San Diego | Old Town Transit Center | Economy | $118 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/8/2026 8:15:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/9/2026 5:45:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 35h 30m
|
||
| FlixBus | 38h 25m | 5:20 AM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $118 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/8/2026 5:20:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/9/2026 5:45:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 38h 25m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 52h 40m | 7:35 PM | Houston | Downtown Houston | 10:15 PM | San Diego | Seaport Village | Economy | $152 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/9/2026 7:35:00 PM to Seaport Village, San Diego (USA) arriving at 11/11/2026 10:15:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 52h 40m
|
||
| FlixBus | 48h 10m | 7:35 PM | Houston | Downtown Houston | 5:45 PM | San Diego | Old Town Transit Center | Economy | $152 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 11/9/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/11/2026 5:45:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 48h 10m
|
||
| Greyhound US | 40h 25m | 2:00 AM | Houston | Harrisburg Blvd Station | 4:25 PM | San Diego | Old Town Transit Center | Economy | $153 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/9/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/10/2026 4:25:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 40h 25m
|
||
| Greyhound US | 42h 20m | 2:00 AM | Houston | Harrisburg Blvd Station | 6:20 PM | San Diego | San Ysidro Transit Center | Economy | $153 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/9/2026 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/10/2026 6:20:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 42h 20m
|
||
| FlixBus | 54h 40m | 5:35 PM | Houston | SW Agencia Autobuses | 10:15 PM | San Diego | Seaport Village | Economy | $156 |
A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 11/9/2026 5:35:00 PM to Seaport Village, San Diego (USA) arriving at 11/11/2026 10:15:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 54h 40m
|
-
-
Greyhound US35h 30m08:15 AMHoustonHarrisburg Blvd Station2:05 PMYuma, AZBus Stop0EconomyA Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 11/8/2026 8:15:00 AM to Bus Stop, Yuma, AZ (USA) arriving at 11/9/2026 2:05:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 30h 50m
-
Greyhound US4h 25m02:20 PMYuma, AZBus Stop5:45 PMSan DiegoOld Town Transit Center0EconomyA Bus from Greyhound US goes from Bus Stop, Yuma, AZ (USA) at 11/9/2026 2:20:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/9/2026 5:45:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 4h 25m
Waiting Time 0h 15m -
Best Price Offer: The price for the cheapest bus from Houston to San Diego is $116 on 11/8/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Houston and San Diego
Facts about the bus from Houston to San Diego
Compare all providers like FlixBus, Greyhound US and Valley Transit that travel 24 times every day by bus from Houston to San Diego in one click! Book your bus ticket from Houston to San Diego starting from $116!
| Cheapest Bus | $116 |
| Fastest Bus | 33h 30m |
| Earliest Bus | 11:30 AM |
| Latest Bus | 7:35 PM |
| Daily Bus Routes | 24 Ø |
| Distance | 1,301.0 miles |
| Bus Companies | FlixBus, Greyhound US and Valley Transit |
Cheapest bus connections from Houston to San Diego
Every day, 24 buses from 3 bus companies leave Houston for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/03/2026 and for the following days.
The cheapest time to travel from Houston to San Diego
How to save money travelling from Houston to San Diego
Book the ticket from Houston to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to San Diego, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to San Diego are also emptier.All bus stations and stops in Houston and San Diego
In the map below, you can see where to find all bus stations in Houston and San Diego.
Service and Comfort on the bus from Houston to San Diego
FAQs about the Houston to San Diego bus
How much does a Houston San Diego bus trip cost?
How much could I save by comparing buses from Houston to San Diego?
On average, how many connections are available from Houston to San Diego each day?
How long does a bus journey from Houston to San Diego take?
What time is the first bus from Houston to San Diego?
What time is the last bus from Houston to San Diego?
Which bus companies operate the Houston San Diego route?
Is there a direct bus between Houston and San Diego?
What can I take with me on the Houston to San Diego bus route?
What equipment is available for the Houston San Diego bus route?
How does CheckMyBus find the best bus deals from Houston to San Diego?
How does CheckMyBus technology work for trips from Houston to San Diego?
Available seat classes which are offered on the bus route Houston to San Diego
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Houston and to San Diego
- Bus Routes to Houston
- Bus Amarillo, TX - Houston
- Buses Arlington, TX to Houston
- From Austin to Houston bus
- Bus Baton Rouge to Houston
- Buses Corpus Christi to Houston
- Dallas to Houston bus
- Buses El Paso, TX - Houston
- Bus to Houston from Kansas City
- Buses Lake Charles, LA - Houston
- Bus Laredo, TX to Houston
- Bus Los Angeles - Houston
- From Miami to Houston bus
- Buses to Houston from Montgomery, AL
- Bus from New Orleans, LA to Houston
- Bus Phoenix, AZ - Houston
- Bus Raleigh, NC to Houston
- Bus from San Antonio, TX to Houston
- Bus to Houston from Tampa
- From Tucson, AZ to Houston bus
- Victoria, TX to Houston bus
- Bus Routes to San Diego
- Anaheim, CA to San Diego bus
- Bus Boise - San Diego
- Buses to San Diego from Calexico, CA
- Bus Dayton, OH - San Diego
- Denver to San Diego bus
- Buses Downey, CA to San Diego
- Buses El Centro, CA to San Diego
- Buses from Mexico City to San Diego
- Buses Modesto, CA - San Diego
- From Perris, CA to San Diego bus
- Bus from Phoenix, AZ to San Diego
- Bus Riverside, CA to San Diego
- Buses to San Diego from Rochester, NY
- Sacramento to San Diego bus
- Buses from Salt Lake City, UT to San Diego
- San Bernardino, CA to San Diego bus
- Bus from San Francisco to San Diego
- Bus from San Jose, CA to San Diego
- Buses to San Diego from Stockton, CA
- Buses Tucson, AZ to San Diego
