Bus Denver to San Diego - Compare all Companies

Compare all timetables for the bus from Denver to San Diego

Here is a selection of the cheapest bus trips from the schedule from Denver to San Diego from various bus operators like Greyhound US or FlixBus for the next days.

today

$110

tomorrow

$110

Thursday

$111

Friday

$103

Saturday

$109

Sunday

$108

Monday

$119

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	47h 45m	7:35 PM	Denver	Union Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$110	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/3/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 11/5/2026 6:20:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 47h 45m
Greyhound US	25h 55m	11:05 AM	Denver	Union Station	12:00 PM	San Diego	San Ysidro Transit Center	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/3/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/4/2026 12:00:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 55m
Greyhound US	31h 5m	11:05 AM	Denver	Union Station	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/3/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/4/2026 5:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 31h 5m
Greyhound US	41h 25m	7:35 PM	Denver	Union Station	12:00 PM	San Diego	San Ysidro Transit Center	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/3/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 11/5/2026 12:00:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 41h 25m
Greyhound US	32h 45m	11:05 AM	Denver	Union Station	6:50 PM	San Diego	Old Town Transit Center	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/3/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/4/2026 6:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 32h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 15m	11:05 AM	Denver	Union Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$110	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/4/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/5/2026 6:20:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 32h 15m
Greyhound US	32h 45m	11:05 AM	Denver	Union Station	6:50 PM	San Diego	Old Town Transit Center	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/4/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/5/2026 6:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 32h 45m
Greyhound US	25h 55m	11:05 AM	Denver	Union Station	12:00 PM	San Diego	San Ysidro Transit Center	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/4/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/5/2026 12:00:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 55m
FlixBus	46h 20m	2:10 PM	Denver	Union Station	11:30 AM	San Diego	Old Town Transit Center	Economy	$112	A Bus from FlixBus goes from Union Station, Denver (USA) at 11/4/2026 2:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/6/2026 11:30:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 46h 20m
FlixBus	46h 50m	2:10 PM	Denver	Union Station	12:00 PM	San Diego	San Ysidro Transit Center	Economy	$112	A Bus from FlixBus goes from Union Station, Denver (USA) at 11/4/2026 2:10:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 11/6/2026 12:00:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 46h 50m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 55m	11:05 AM	Denver	Union Station	12:00 PM	San Diego	San Ysidro Transit Center	Economy	$111	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/5/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/6/2026 12:00:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 55m
Greyhound US	32h 15m	11:05 AM	Denver	Union Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$113	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/5/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/6/2026 6:20:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 32h 15m
Greyhound US	46h 0m	8:10 PM	Denver	Union Station	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$114	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/5/2026 8:10:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 11/7/2026 5:10:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 46h 0m
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	San Diego	Old Town Transit Center	Economy	$120	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/5/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/6/2026 11:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 25h 25m
Greyhound US	32h 45m	11:05 AM	Denver	Union Station	6:50 PM	San Diego	Old Town Transit Center	Economy	$122	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/5/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/6/2026 6:50:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 32h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 15m	11:05 AM	Denver	Union Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$103	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/6/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/7/2026 6:20:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 32h 15m
Greyhound US	46h 35m	7:35 PM	Denver	Union Station	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$107	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/6/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 11/8/2026 5:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 46h 35m
Greyhound US	25h 55m	11:05 AM	Denver	Union Station	12:00 PM	San Diego	San Ysidro Transit Center	Economy	$112	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/6/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/7/2026 12:00:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 25h 55m
Greyhound US	41h 25m	7:35 PM	Denver	Union Station	12:00 PM	San Diego	San Ysidro Transit Center	Economy	$112	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/6/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 11/8/2026 12:00:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 41h 25m
Greyhound US	36h 10m	11:05 AM	Denver	Union Station	10:15 PM	San Diego	Seaport Village	Economy	$117	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/6/2026 11:05:00 AM to Seaport Village, San Diego (USA) arriving at 11/7/2026 10:15:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 36h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 15m	11:05 AM	Denver	Union Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$109	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/7/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/8/2026 6:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 32h 15m
Greyhound US	36h 10m	11:05 AM	Denver	Union Station	10:15 PM	San Diego	Seaport Village	Economy	$117	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/7/2026 11:05:00 AM to Seaport Village, San Diego (USA) arriving at 11/8/2026 10:15:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 36h 10m
Greyhound US	32h 45m	11:05 AM	Denver	Union Station	6:50 PM	San Diego	Old Town Transit Center	Economy	$118	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/7/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/8/2026 6:50:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 32h 45m
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	San Diego	Old Town Transit Center	Economy	$119	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/7/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/8/2026 11:30:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 25h 25m
Greyhound US	45h 15m	8:10 PM	Denver	Union Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$120	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/7/2026 8:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/9/2026 4:25:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 45h 15m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	46h 35m	7:35 PM	Denver	Union Station	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$108	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/8/2026 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 11/10/2026 5:10:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 46h 35m
Greyhound US	32h 15m	11:05 AM	Denver	Union Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$109	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/8/2026 11:05:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 11/9/2026 6:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 32h 15m
Greyhound US	41h 10m	7:35 PM	Denver	Union Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$117	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/8/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/10/2026 11:45:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 41h 10m
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	San Diego	Old Town Transit Center	Economy	$118	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/8/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/9/2026 11:30:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 25h 25m
Greyhound US	36h 10m	11:05 AM	Denver	Union Station	10:15 PM	San Diego	Seaport Village	Economy	$118	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/8/2026 11:05:00 AM to Seaport Village, San Diego (USA) arriving at 11/9/2026 10:15:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 36h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	32h 45m	11:05 AM	Denver	Union Station	6:50 PM	San Diego	Old Town Transit Center	Economy	$119	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/9/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/10/2026 6:50:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 32h 45m
Greyhound US	25h 25m	11:05 AM	Denver	Union Station	11:30 AM	San Diego	Old Town Transit Center	Economy	$120	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/9/2026 11:05:00 AM to Old Town Transit Center, San Diego (USA) arriving at 11/10/2026 11:30:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 25h 25m
Greyhound US	36h 10m	11:05 AM	Denver	Union Station	10:15 PM	San Diego	Seaport Village	Economy	$120	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/9/2026 11:05:00 AM to Seaport Village, San Diego (USA) arriving at 11/10/2026 10:15:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 36h 10m
Greyhound US	41h 10m	7:35 PM	Denver	Union Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$122	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/9/2026 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/11/2026 11:45:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 41h 10m
Greyhound US	45h 15m	8:10 PM	Denver	Union Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$123	A Bus from Greyhound US goes from Union Station, Denver (USA) at 11/9/2026 8:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 11/11/2026 4:25:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 45h 15m

Best Price Offer: The price for the cheapest bus from Denver to San Diego is $103 on 11/6/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Denver and San Diego

See here how frequent the connections between Denver and San Diego are, during different times and days of the week.

Wednesday is the busiest day, with more than 21 daily buses from Denver to San Diego. Monday has instead the fewest connections, with only 6 daily coaches between Denver and San Diego.

The busiest time of the day is the Evening, with 45 buses from Denver to San Diego, while Afternoon sees the fewest connections between Denver and San Diego, with 6 offers.

Facts about the bus from Denver to San Diego

Compare all providers like Greyhound US and FlixBus that travel 13 times every day by bus from Denver to San Diego in one click! Book your bus ticket from Denver to San Diego starting from $103!

Cheapest Bus	$103
Fastest Bus	24h 5m
Earliest Bus	11:05 AM
Latest Bus	8:10 PM
Daily Bus Routes	13 Ø
Distance	832.5 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Denver to San Diego

Every day, 13 buses from 2 bus companies leave Denver for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/01

Monday 11/02

Tuesday 11/03

$111

Wednesday 11/04

$115

Thursday 11/05

$123

Friday 11/06

$109

Saturday 11/07

$109

Sunday 11/08

$117

Monday 11/09

$119

Tuesday 11/10

$111

Wednesday 11/11

$117

Thursday 11/12

$126

Friday 11/13

Saturday 11/14

$111

Sunday 11/15

$114

Monday 11/16

$127

Tuesday 11/17

$116

Wednesday 11/18

Thursday 11/19

$142

Friday 11/20

$157

Saturday 11/21

$165

Sunday 11/22

Monday 11/23

$193

Tuesday 11/24

$175

Wednesday 11/25

$176

Thursday 11/26

Friday 11/27

$150

Saturday 11/28

The cheapest time to travel from Denver to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Denver to San Diego, for the next 30 days.

With a price starting from $103, Friday is the cheapest day for a bus from Denver to San Diego. Monday instead is the most expensive day with prices starting from $119.

Morning is the cheapest day time for bus tickets from Denver to San Diego, with $103. Afternoon is the most expensive time of the day with prices starting from $112.

How to save money travelling from Denver to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Denver to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Denver to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Denver to San Diego are also emptier.

Beloved bus companies from Denver to San Diego

These are the most booked bus companies between Denver to San Diego from our users.

Greyhound US from Denver to San Diego

Here you will find the key facts about the Greyhound US bus route Denver to San Diego:

Cheapest Price	$103
Fastest Bus	24h 5m
Earliest Bus	11:05 AM
Last Bus	8:10 PM
Daily Connections	12 Ø
Found on	10/10/2026

All bus stations and stops in Denver and San Diego

In the map below, you can see where to find all bus stations in Denver and San Diego.

Federal Blvd & W 19th Ave Bus Stop

Federal Blvd & W 19th Ave Federal Blvd & W 19th Ave

Union Station

Wynkoop St 1701

Bus Stop

Colorado Station

E Evans Ave 4401

19th St. Bus Station

19th St 1055

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Seaport Village

W Harbor Dr 789

Santa Fe Depot

Kettner Blvd 1050

Downtown

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Denver to San Diego? Compare all modes of transports from Denver to San Diego.

Service and Comfort on the bus from Denver to San Diego

Want to know which seat classes are available on the buses from Denver to San Diego? Or which bus companies serve the route Denver to San Diego? Below you will find answers to your questions.

FAQs about the Denver to San Diego bus

How much does a Denver San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $103 and takes 31h 15m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Denver to San Diego?

This route is offered by 2 companies with a range of ticket prices between $103 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Denver to San Diego each day?

Every day, the Denver to San Diego bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Denver to San Diego take?

The fastest bus from Denver to San Diego is offered by Greyhound US and takes 24h 5m. Bus tickets for this connection cost $116. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Denver to San Diego?

The earliest bus arriving in San Diego from Denver starts at 11:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Denver to San Diego?

The latest bus trip departing from Denver for San Diego starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Denver San Diego route?

When traveling by bus from Denver to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Denver and San Diego?

You can check all the direct connections between Denver and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Denver to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Denver San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Denver San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Denver to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Denver to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 13 daily trips between Denver and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Denver to San Diego?

Prices and availability for 13 trips between Denver and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Denver to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Denver and to San Diego

Here’s an overview of the most popular bus routes to Denver and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!