Bus from Santa Ana, CA to San Diego from $20

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Compare all timetables for the bus from Santa Ana, CA to San Diego

Here is a selection of the cheapest bus trips from the schedule from Santa Ana, CA to San Diego from various bus operators like Limousine Express, FlixBus or Greyhound US for the next days.

today
from $21
tomorrow
from $20
Tuesday
from $21
Wednesday
from $22
Thursday
from $23
Friday
from $21
Saturday
from $20

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    1h 50m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $21
  • FlixBus
    1h 50m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $21
  • FlixBus
    1h 25m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:00 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $21
  • Greyhound US
    2h 25m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $27
  • Limousine Express
    3h 5m
    0
    5:55 AM
    Santa Ana, CA
    Bus Stop
    9:00 AM
    San Diego
    San Ysidro Transit Center
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    1h 50m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $20
  • FlixBus
    1h 25m
    0
    7:40 PM
    Santa Ana, CA
    Bus Stop
    9:05 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $20
  • FlixBus
    1h 50m
    0
    7:40 PM
    Santa Ana, CA
    Bus Stop
    9:30 PM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $20
  • Greyhound US
    2h 25m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $27
  • Limousine Express
    3h 5m
    0
    5:55 AM
    Santa Ana, CA
    Bus Stop
    9:00 AM
    San Diego
    San Ysidro Transit Center
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    1h 50m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $21
  • FlixBus
    1h 25m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:00 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $21
  • Greyhound US
    1h 50m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $27
  • Greyhound US
    2h 25m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $29
  • Limousine Express
    3h 5m
    0
    5:55 AM
    Santa Ana, CA
    Bus Stop
    9:00 AM
    San Diego
    San Ysidro Transit Center
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    1h 50m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $22
  • FlixBus
    1h 25m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:00 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $22
  • Greyhound US
    1h 50m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $27
  • Greyhound US
    1h 45m
    0
    10:05 PM
    Santa Ana, CA
    Bus Stop
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $28
  • Limousine Express
    3h 5m
    0
    5:55 AM
    Santa Ana, CA
    Bus Stop
    9:00 AM
    San Diego
    San Ysidro Transit Center
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    1h 50m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $23
  • FlixBus
    1h 25m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:00 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $23
  • Greyhound US
    1h 50m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $27
  • Greyhound US
    1h 45m
    0
    10:05 PM
    Santa Ana, CA
    Bus Stop
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $29
  • Limousine Express
    3h 5m
    0
    5:55 AM
    Santa Ana, CA
    Bus Stop
    9:00 AM
    San Diego
    San Ysidro Transit Center
    0
    Limousine Express
    Economy
    $39
  • Did you know that if you travel from Santa Ana, CA to San Diego via Anaheim, CA, you can save more than $5? You will find the corresponding connections below.
    • Save more than 22%
      2h 5m
      Santa Ana, CA
      7 mi
      7:10 AM
      Anaheim, CA
      Anaheim Regional Transportation Intermodal Center
      9:15 AM
      San Diego
      Old Town Transit Center
      0 mi
      Economy
      $18

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    1h 25m
    0
    7:40 PM
    Santa Ana, CA
    Bus Stop
    9:05 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $21
  • FlixBus
    1h 50m
    0
    7:40 PM
    Santa Ana, CA
    Bus Stop
    9:30 PM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $21
  • Greyhound US
    1h 50m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $29
  • Greyhound US
    2h 25m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $30
  • Limousine Express
    3h 5m
    0
    5:55 AM
    Santa Ana, CA
    Bus Stop
    9:00 AM
    San Diego
    San Ysidro Transit Center
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    1h 50m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:25 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $20
  • FlixBus
    1h 25m
    0
    2:35 PM
    Santa Ana, CA
    Bus Stop
    4:00 PM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $20
  • Greyhound US
    1h 45m
    0
    10:05 PM
    Santa Ana, CA
    Bus Stop
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $27
  • Greyhound US
    1h 50m
    0
    7:40 AM
    Santa Ana, CA
    Bus Stop
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $28
  • Limousine Express
    3h 5m
    0
    5:55 AM
    Santa Ana, CA
    Bus Stop
    9:00 AM
    San Diego
    San Ysidro Transit Center
    0
    Limousine Express
    Economy
    $38

Frequency of bus connections between Santa Ana, CA and San Diego

See here how frequent the connections between Santa Ana, CA and San Diego are, during different times and days of the week.
Sunday is the busiest day, with more than 36 daily buses from Santa Ana, CA to San Diego. Wednesday has instead the fewest connections, with only 19 daily coaches between Santa Ana, CA and San Diego.
The busiest time of the day is the Evening, with 93 buses from Santa Ana, CA to San Diego, while Night sees the fewest connections between Santa Ana, CA and San Diego, with 10 offers.

Facts about the bus from Santa Ana, CA to San Diego

Compare all providers like Limousine Express, FlixBus and Greyhound US that travel 28 times every day by bus from Santa Ana, CA to San Diego in one click! Book your bus ticket from Santa Ana, CA to San Diego starting from $20!

Cheapest Bus $20
Fastest Bus 1h 25m
Earliest Bus 5:55 AM
Latest Bus 10:15 PM
Daily Bus Routes 28 Ø
Distance 82.0 miles
Bus Companies Limousine Express, FlixBus and Greyhound US

Cheapest bus connections from Santa Ana, CA to San Diego

Every day, 28 buses from 3 bus companies leave Santa Ana, CA for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/29/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/29
$27
Monday 06/30
$27
Tuesday 07/01
$38
Wednesday 07/02
$38
Thursday 07/03
$39
Friday 07/04
$21
Saturday 07/05
$38
Sunday 07/06
$33
Monday 07/07
$27
Tuesday 07/08
$27
Wednesday 07/09
$38
Thursday 07/10
$27
Friday 07/11
$33
Saturday 07/12
$38
Sunday 07/13
$39
Monday 07/14
$38
Tuesday 07/15
$39
Wednesday 07/16
$33
Thursday 07/17
Friday 07/18
$39
Saturday 07/19
$33
Sunday 07/20
Monday 07/21
$38
Tuesday 07/22
$39
Wednesday 07/23
Thursday 07/24
$39
Friday 07/25
$33
Saturday 07/26

The cheapest time to travel from Santa Ana, CA to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Santa Ana, CA to San Diego, for the next 30 days.
With a price starting from $20, Monday is the cheapest day for a bus from Santa Ana, CA to San Diego. Thursday instead is the most expensive day with prices starting from $23.
Morning is the cheapest day time for bus tickets from Santa Ana, CA to San Diego, with $20. Night is the most expensive time of the day with prices starting from $38.

How to save money travelling from Santa Ana, CA to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santa Ana, CA to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santa Ana, CA to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Santa Ana, CA to San Diego are also emptier.

Beloved bus companies from Santa Ana, CA to San Diego

These are the most booked bus companies between Santa Ana, CA to San Diego from our users.

Limousine Express from Santa Ana, CA to San Diego

Limousine Express

Here you will find the key facts about the Limousine Express bus route Santa Ana, CA to San Diego:

Cheapest Price $38
Fastest Bus 2h 15m
Earliest Bus 5:55 AM
Last Bus 10:15 PM
Daily Connections 17 Ø
Found on 6/28/2025

FlixBus from Santa Ana, CA to San Diego

FlixBus

Here you will find the key facts about the FlixBus bus route Santa Ana, CA to San Diego:

Cheapest Price $20
Fastest Bus 1h 25m
Earliest Bus 2:35 PM
Last Bus 7:40 PM
Daily Connections 5 Ø
Found on 6/28/2025

All bus stations and stops in Santa Ana, CA and San Diego

In the map below, you can see where to find all bus stations in Santa Ana, CA and San Diego.

Service and Comfort on the bus from Santa Ana, CA to San Diego

Want to know which seat classes are available on the buses from Santa Ana, CA to San Diego? Or which bus companies serve the route Santa Ana, CA to San Diego? Below you will find answers to your questions.

FAQs about the Santa Ana, CA to San Diego bus

How much does a Santa Ana, CA San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $20 and takes 1h 50m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Santa Ana, CA to San Diego?

This route is offered by 3 companies with a range of ticket prices between $20 and $42. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Santa Ana, CA to San Diego each day?

Every day, the Santa Ana, CA to San Diego bus route is served by approximately 28 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Santa Ana, CA to San Diego take?

The fastest bus from Santa Ana, CA to San Diego is offered by FlixBus and takes 1h 25m. Bus tickets for this connection cost $21. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Santa Ana, CA to San Diego?

The earliest bus arriving in San Diego from Santa Ana, CA starts at 5:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Santa Ana, CA to San Diego?

The latest bus trip departing from Santa Ana, CA for San Diego starts at 10:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Santa Ana, CA San Diego route?

When traveling by bus from Santa Ana, CA to San Diego, passengers can travel with Limousine Express, FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Santa Ana, CA and San Diego?

You can check all the direct connections between Santa Ana, CA and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Limousine Express, FlixBus and Greyhound US.

What can I take with me on the Santa Ana, CA to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Santa Ana, CA San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Ana, CA San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Ana, CA to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Santa Ana, CA to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santa Ana, CA and to San Diego

Here’s an overview of the most popular bus routes to Santa Ana, CA and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
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