Bus from San Francisco to Santa Ana, CA from $45

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Compare all timetables for the bus from San Francisco to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from San Francisco to Santa Ana, CA from various bus operators like Greyhound US or FlixBus for the next days.
today
from $69
tomorrow
Sunday
from $60
Monday
Tuesday
from $45
Wednesday
from $59
Thursday

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    15h 30m
    0
    6:30 AM
    San Francisco
    Bus Station Transbay
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $69
  • FlixBus
    13h 55m
    0
    8:05 AM
    San Francisco
    5th/Townsend
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $92
  • Greyhound US
    10h 50m
    0
    10:40 PM
    San Francisco
    Bus Station Transbay
    9:30 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $104
  • FlixBus
    11h 0m
    0
    8:35 PM
    San Francisco
    5th/Townsend
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $105
  • Greyhound US
    15h 35m
    0
    4:00 PM
    San Francisco
    Bus Station Transbay
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $106
  • Did you know that if you travel from San Francisco to Santa Ana, CA via San Jose, CA, you can save more than $16? You can find the corresponding connections below.
    • Busbud
      16h 0m
      0
      6:00 AM
      San Francisco
      Salesforce Transit Center
      7:50 AM
      San Jose, CA
      Bus Stop
      0
      Busbud
      Economy
      $12
      • Waiting Time 0h 15m
    • FlixBus
      13h 55m
      0
      8:05 AM
      San Jose, CA
      Bus Stop
      10:00 PM
      Santa Ana, CA
      Bus Stop
      0
      FlixBus
      Economy
      $41
    Travel time is 5h 10m longer, but you will save $16

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    10h 5m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    9:30 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $60
  • Greyhound US
    15h 35m
    0
    4:00 PM
    San Francisco
    Bus Station Transbay
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $61
  • FlixBus
    11h 0m
    0
    8:35 PM
    San Francisco
    5th/Townsend
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $61
  • Greyhound US
    10h 50m
    0
    10:40 PM
    San Francisco
    Bus Station Transbay
    9:30 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $64
  • FlixBus
    13h 55m
    0
    8:05 AM
    San Francisco
    5th/Townsend
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $69

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    15h 30m
    0
    6:30 AM
    San Francisco
    Bus Station Transbay
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $45
  • FlixBus
    10h 5m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    9:30 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $47
  • Greyhound US
    15h 35m
    0
    4:00 PM
    San Francisco
    Bus Station Transbay
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $48
  • Greyhound US
    10h 50m
    0
    10:40 PM
    San Francisco
    Bus Station Transbay
    9:30 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $66

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Greyhound US
    15h 30m
    0
    6:30 AM
    San Francisco
    Bus Station Transbay
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $59
  • Greyhound US
    10h 50m
    0
    10:40 PM
    San Francisco
    Bus Station Transbay
    9:30 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $62
  • FlixBus
    10h 5m
    0
    11:25 PM
    San Francisco
    5th/Townsend
    9:30 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $69
  • Greyhound US
    15h 35m
    0
    4:00 PM
    San Francisco
    Bus Station Transbay
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $80
  • FlixBus
    12h 50m
    0
    6:45 PM
    San Francisco
    5th/Townsend
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $80

Frequency of bus connections between San Francisco and Santa Ana, CA

See here how frequent the connections between San Francisco and Santa Ana, CA are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from San Francisco to Santa Ana, CA. Tuesday has instead the fewest connections, with only 4 daily coaches between San Francisco and Santa Ana, CA.
The busiest time of the day is the Evening, with 11 buses from San Francisco to Santa Ana, CA, while Afternoon sees the fewest connections between San Francisco and Santa Ana, CA, with 4 offers.

Facts about the bus from San Francisco to Santa Ana, CA

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from San Francisco to Santa Ana, CA in one click! Book your bus ticket from San Francisco to Santa Ana, CA starting from $45!

Cheapest Bus $45
Fastest Bus 10h 5m
Earliest Bus 6:30 AM
Latest Bus 11:25 PM
Daily Bus Routes 5 Ø
Distance 376.9 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from San Francisco to Santa Ana, CA

Every day, 5 buses from 2 bus companies leave San Francisco for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/16
Monday 03/17
Tuesday 03/18
Wednesday 03/19
Thursday 03/20
Friday 03/21
$69
Saturday 03/22
Sunday 03/23
$60
Monday 03/24
Tuesday 03/25
$45
Wednesday 03/26
$59
Thursday 03/27
Friday 03/28
Saturday 03/29
$67
Sunday 03/30
Monday 03/31
Tuesday 04/01
Wednesday 04/02
Thursday 04/03
Friday 04/04
Saturday 04/05
Sunday 04/06
Monday 04/07
Tuesday 04/08
Wednesday 04/09
Thursday 04/10
Friday 04/11
Saturday 04/12

The cheapest time to travel from San Francisco to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from San Francisco to Santa Ana, CA, for the next 30 days.
With a price starting from $45, Tuesday is the cheapest day for a bus from San Francisco to Santa Ana, CA. Friday instead is the most expensive day with prices starting from $69.
Morning is the cheapest day time for bus tickets from San Francisco to Santa Ana, CA, with $45. Afternoon is the most expensive time of the day with prices starting from $48.

How to save money travelling from San Francisco to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Francisco to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Santa Ana, CA are also emptier.

All bus stations and stops in San Francisco and Santa Ana, CA

In the map below, you can see where to find all bus stations in San Francisco and Santa Ana, CA.

Service and Comfort on the bus from San Francisco to Santa Ana, CA

Want to know which seat classes are available on the buses from San Francisco to Santa Ana, CA? Or which bus companies serve the route San Francisco to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the San Francisco to Santa Ana, CA bus

How much does a San Francisco Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $45 and takes 15h 30m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from San Francisco to Santa Ana, CA?

This route is offered by 2 companies with a range of ticket prices between $45 and $115. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from San Francisco to Santa Ana, CA each day?

Every day, the San Francisco to Santa Ana, CA bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Francisco to Santa Ana, CA take?

The fastest bus from San Francisco to Santa Ana, CA is offered by FlixBus and takes 10h 5m. Bus tickets for this connection cost $115. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Francisco to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from San Francisco starts at 6:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Francisco to Santa Ana, CA?

The latest bus trip departing from San Francisco for Santa Ana, CA starts at 11:25 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Francisco Santa Ana, CA route?

When traveling by bus from San Francisco to Santa Ana, CA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Francisco and Santa Ana, CA?

You can check all the direct connections between San Francisco and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the San Francisco to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Francisco Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Francisco Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Francisco to Santa Ana, CA on your planned travel date.

Available seat classes which are offered on the bus route San Francisco to Santa Ana, CA

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Francisco and to Santa Ana, CA

Here’s an overview of the most popular bus routes to San Francisco and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!
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