Compare all timetables for the bus from San Francisco to Santa Ana, CA
Cheapest bus trips today
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Greyhound US10h 50m010:40 PMSan FranciscoBus Station Transbay9:30 AMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/27/2025 10:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/28/2025 9:30:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 10h 50m
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FlixBus10h 5m011:25 PMSan Francisco5th/Townsend9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/27/2025 11:25:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/28/2025 9:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 10h 5m
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Greyhound US15h 30m06:30 AMSan FranciscoBus Station Transbay10:00 PMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/27/2025 6:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/27/2025 10:00:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 15h 30m
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FlixBus13h 30m08:30 AMSan Francisco5th/Townsend10:00 PMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/27/2025 8:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/27/2025 10:00:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 13h 30m
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Greyhound US15h 35m04:00 PMSan FranciscoBus Station Transbay7:35 AMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/27/2025 4:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/28/2025 7:35:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 15h 35m
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Busbud10h 5m011:25 PMSan Francisco5th/Townsend7:40 AMLos AngelesUnion Station0EconomyA Bus from Busbud goes from 5th/Townsend, San Francisco (USA) at 6/28/2025 11:25:00 PM to Union Station, Los Angeles (USA) arriving at 6/29/2025 7:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 15m
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FlixBus1h 10m08:20 AMLos AngelesUnion Station9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/29/2025 8:20:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 9:30:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 10m
Waiting Time 0h 40m -
Cheapest bus trips tomorrow
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Greyhound US15h 35m04:00 PMSan FranciscoBus Station Transbay7:35 AMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/28/2025 4:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 7:35:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 15h 35m
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Greyhound US10h 50m010:40 PMSan FranciscoBus Station Transbay9:30 AMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/28/2025 10:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 9:30:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 10h 50m
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FlixBus11h 25m08:10 PMSan Francisco5th/Townsend7:35 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/28/2025 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 7:35:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 11h 25m
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FlixBus10h 5m011:25 PMSan Francisco5th/Townsend9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/28/2025 11:25:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 9:30:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 10h 5m
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Greyhound US15h 30m06:30 AMSan FranciscoBus Station Transbay10:00 PMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/28/2025 6:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/28/2025 10:00:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 15h 30m
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Busbud10h 5m011:25 PMSan Francisco5th/Townsend7:40 AMLos AngelesUnion Station0EconomyA Bus from Busbud goes from 5th/Townsend, San Francisco (USA) at 6/28/2025 11:25:00 PM to Union Station, Los Angeles (USA) arriving at 6/29/2025 7:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 15m
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FlixBus1h 10m08:20 AMLos AngelesUnion Station9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/29/2025 8:20:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 9:30:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 10m
Waiting Time 0h 40m -
Cheapest bus trips Sunday
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FlixBus10h 5m011:25 PMSan Francisco5th/Townsend9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/29/2025 11:25:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/30/2025 9:30:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 10h 5m
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FlixBus13h 30m08:30 AMSan Francisco5th/Townsend10:00 PMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/29/2025 8:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 10:00:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 13h 30m
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Greyhound US10h 50m010:40 PMSan FranciscoBus Station Transbay9:30 AMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/29/2025 10:40:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/30/2025 9:30:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 10h 50m
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Greyhound US15h 35m04:00 PMSan FranciscoBus Station Transbay7:35 AMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 6/29/2025 4:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/30/2025 7:35:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 15h 35m
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FlixBus11h 25m08:10 PMSan Francisco5th/Townsend7:35 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 6/29/2025 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/30/2025 7:35:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 11h 25m
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Busbud10h 5m011:25 PMSan Francisco5th/Townsend7:40 AMLos AngelesUnion Station0EconomyA Bus from Busbud goes from 5th/Townsend, San Francisco (USA) at 6/28/2025 11:25:00 PM to Union Station, Los Angeles (USA) arriving at 6/29/2025 7:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 15m
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FlixBus1h 10m08:20 AMLos AngelesUnion Station9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/29/2025 8:20:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 9:30:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 10m
Waiting Time 0h 40m -
Cheapest bus trips Thursday
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FlixBus13h 5m08:55 AMSan Francisco5th/Townsend10:00 PMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 7/3/2025 8:55:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/3/2025 10:00:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 13h 5m
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FlixBus10h 5m011:25 PMSan Francisco5th/Townsend9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 7/3/2025 11:25:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/4/2025 9:30:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 10h 5m
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Greyhound US15h 30m06:30 AMSan FranciscoBus Station Transbay10:00 PMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 7/3/2025 6:30:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 7/3/2025 10:00:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 15h 30m
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Greyhound US15h 35m04:00 PMSan FranciscoBus Station Transbay7:35 AMSanta Ana, CABus Stop0EconomyA Bus from Greyhound US goes from Bus Station Transbay, San Francisco (USA) at 7/3/2025 4:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/4/2025 7:35:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 15h 35m
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FlixBus11h 25m08:10 PMSan Francisco5th/Townsend7:35 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from 5th/Townsend, San Francisco (USA) at 7/3/2025 8:10:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 7/4/2025 7:35:00 AM. 50 Economy ticket for $97 per person are available. Travel duration is 11h 25m
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Busbud10h 5m011:25 PMSan Francisco5th/Townsend7:40 AMLos AngelesUnion Station0EconomyA Bus from Busbud goes from 5th/Townsend, San Francisco (USA) at 6/28/2025 11:25:00 PM to Union Station, Los Angeles (USA) arriving at 6/29/2025 7:40:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 15m
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FlixBus1h 10m08:20 AMLos AngelesUnion Station9:30 AMSanta Ana, CABus Stop0EconomyA Bus from FlixBus goes from Union Station, Los Angeles (USA) at 6/29/2025 8:20:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2025 9:30:00 AM. 50 Economy ticket for $10 per person are available. Travel duration is 1h 10m
Waiting Time 0h 40m -
Frequency of bus connections between San Francisco and Santa Ana, CA
Facts about the bus from San Francisco to Santa Ana, CA
Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from San Francisco to Santa Ana, CA in one click! Book your bus ticket from San Francisco to Santa Ana, CA starting from $62!
Cheapest Bus | $62 |
Fastest Bus | 10h 5m |
Earliest Bus | 6:30 AM |
Latest Bus | 11:25 PM |
Daily Bus Routes | 6 Ø |
Distance | 376.9 miles |
Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from San Francisco to Santa Ana, CA
Every day, 6 buses from 2 bus companies leave San Francisco for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/27/2025 and for the following days.
The cheapest time to travel from San Francisco to Santa Ana, CA
How to save money travelling from San Francisco to Santa Ana, CA
Book the ticket from San Francisco to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Francisco to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Francisco to Santa Ana, CA are also emptier.All bus stations and stops in San Francisco and Santa Ana, CA
In the map below, you can see where to find all bus stations in San Francisco and Santa Ana, CA.
Service and Comfort on the bus from San Francisco to Santa Ana, CA
FAQs about the San Francisco to Santa Ana, CA bus
How much does a San Francisco Santa Ana, CA bus trip cost?
How much could I save by comparing buses from San Francisco to Santa Ana, CA?
On average, how many connections are available from San Francisco to Santa Ana, CA each day?
How long does a bus journey from San Francisco to Santa Ana, CA take?
What time is the first bus from San Francisco to Santa Ana, CA?
What time is the last bus from San Francisco to Santa Ana, CA?
Which bus companies operate the San Francisco Santa Ana, CA route?
Is there a direct bus between San Francisco and Santa Ana, CA?
What can I take with me on the San Francisco to Santa Ana, CA bus route?
What equipment is available for the San Francisco Santa Ana, CA bus route?
Available seat classes which are offered on the bus route San Francisco to Santa Ana, CA
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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