Bus from San Diego to Santa Ana, CA from $21

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Compare all timetables for the bus from San Diego to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from San Diego to Santa Ana, CA from various bus operators like Limousine Express, Greyhound US or FlixBus for the next days.

today
from $21
tomorrow
from $21
Sunday
from $21
Monday
from $21
Tuesday
from $23
Wednesday
Thursday
from $22

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    1h 55m
    0
    7:15 AM
    San Diego
    Old Town Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $21
  • FlixBus
    2h 35m
    0
    11:10 AM
    San Diego
    Seaport Village
    1:45 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $21
  • Greyhound US
    2h 0m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    4:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $22
  • FlixBus
    2h 40m
    0
    7:20 AM
    San Diego
    San Ysidro Transit Center
    10:00 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $32
  • Limousine Express
    3h 0m
    0
    1:15 AM
    San Diego
    San Ysidro Transit Center
    4:15 AM
    Santa Ana, CA
    Bus Stop
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    1h 55m
    0
    7:15 AM
    San Diego
    Old Town Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $21
  • Greyhound US
    2h 0m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    4:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $21
  • FlixBus
    2h 40m
    0
    7:20 AM
    San Diego
    San Ysidro Transit Center
    10:00 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $27
  • Limousine Express
    3h 0m
    0
    1:15 AM
    San Diego
    San Ysidro Transit Center
    4:15 AM
    Santa Ana, CA
    Bus Stop
    0
    Limousine Express
    Economy
    $38
  • Limousine Express
    7h 10m
    0
    2:00 AM
    San Diego
    San Ysidro Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    1h 55m
    0
    7:15 AM
    San Diego
    Old Town Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $21
  • FlixBus
    2h 35m
    0
    11:10 AM
    San Diego
    Seaport Village
    1:45 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $21
  • Greyhound US
    2h 0m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    4:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $22
  • FlixBus
    2h 40m
    0
    7:20 AM
    San Diego
    San Ysidro Transit Center
    10:00 AM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $27
  • Limousine Express
    3h 0m
    0
    1:15 AM
    San Diego
    San Ysidro Transit Center
    4:15 AM
    Santa Ana, CA
    Bus Stop
    0
    Limousine Express
    Economy
    $39

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    1h 55m
    0
    7:15 AM
    San Diego
    Old Town Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $21
  • FlixBus
    2h 35m
    0
    11:10 AM
    San Diego
    Seaport Village
    1:45 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $22
  • Greyhound US
    2h 0m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    4:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $23
  • Limousine Express
    3h 0m
    0
    1:15 AM
    San Diego
    San Ysidro Transit Center
    4:15 AM
    Santa Ana, CA
    Bus Stop
    0
    Limousine Express
    Economy
    $38
  • Limousine Express
    7h 10m
    0
    2:00 AM
    San Diego
    San Ysidro Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Limousine Express
    Economy
    $38

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    1h 55m
    0
    7:15 AM
    San Diego
    Old Town Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $23
  • Greyhound US
    2h 0m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    4:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $25
  • Greyhound US
    1h 45m
    0
    7:35 PM
    San Diego
    Old Town Transit Center
    9:20 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $25

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    1h 55m
    0
    7:15 AM
    San Diego
    Old Town Transit Center
    9:10 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $22
  • Greyhound US
    2h 0m
    0
    2:00 PM
    San Diego
    Old Town Transit Center
    4:00 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $24
  • Greyhound US
    1h 45m
    0
    7:35 PM
    San Diego
    Old Town Transit Center
    9:20 PM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $24

Frequency of bus connections between San Diego and Santa Ana, CA

See here how frequent the connections between San Diego and Santa Ana, CA are, during different times and days of the week.
Sunday is the busiest day, with more than 44 daily buses from San Diego to Santa Ana, CA. Tuesday has instead the fewest connections, with only 3 daily coaches between San Diego and Santa Ana, CA.
The busiest time of the day is the Morning, with 64 buses from San Diego to Santa Ana, CA, while Evening sees the fewest connections between San Diego and Santa Ana, CA, with 23 offers.

Facts about the bus from San Diego to Santa Ana, CA

Compare all providers like Limousine Express, Greyhound US and FlixBus that travel 26 times every day by bus from San Diego to Santa Ana, CA in one click! Book your bus ticket from San Diego to Santa Ana, CA starting from $21!

Cheapest Bus $21
Fastest Bus 1h 45m
Earliest Bus 1:15 AM
Latest Bus 7:35 PM
Daily Bus Routes 26 Ø
Distance 82.0 miles
Bus Companies Limousine Express, Greyhound US and FlixBus

Cheapest bus connections from San Diego to Santa Ana, CA

Every day, 26 buses from 3 bus companies leave San Diego for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/28/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
Thursday 06/26
Friday 06/27
$29
Saturday 06/28
$39
Sunday 06/29
$21
Monday 06/30
$21
Tuesday 07/01
$23
Wednesday 07/02
Thursday 07/03
$22
Friday 07/04
$22
Saturday 07/05
$21
Sunday 07/06
$21
Monday 07/07
$27
Tuesday 07/08
Wednesday 07/09
$24
Thursday 07/10
$20
Friday 07/11
Saturday 07/12
$21
Sunday 07/13
Monday 07/14
Tuesday 07/15
$26
Wednesday 07/16
$20
Thursday 07/17
Friday 07/18
$21
Saturday 07/19

The cheapest time to travel from San Diego to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from San Diego to Santa Ana, CA, for the next 30 days.
With a price starting from $21, Sunday is the cheapest day for a bus from San Diego to Santa Ana, CA. Tuesday instead is the most expensive day with prices starting from $23.
Morning is the cheapest day time for bus tickets from San Diego to Santa Ana, CA, with $21. Night is the most expensive time of the day with prices starting from $38.

How to save money travelling from San Diego to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Diego to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Diego to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Diego to Santa Ana, CA are also emptier.

Beloved bus companies from San Diego to Santa Ana, CA

These are the most booked bus companies between San Diego to Santa Ana, CA from our users.

Limousine Express from San Diego to Santa Ana, CA

Limousine Express

Here you will find the key facts about the Limousine Express bus route San Diego to Santa Ana, CA:

Cheapest Price $38
Fastest Bus 2h 15m
Earliest Bus 1:15 AM
Last Bus 10:00 PM
Daily Connections 31 Ø
Found on 6/26/2025

Greyhound US from San Diego to Santa Ana, CA

Greyhound US

Here you will find the key facts about the Greyhound US bus route San Diego to Santa Ana, CA:

Cheapest Price $21
Fastest Bus 1h 45m
Earliest Bus 6:30 AM
Last Bus 7:35 PM
Daily Connections 4 Ø
Found on 6/26/2025

All bus stations and stops in San Diego and Santa Ana, CA

In the map below, you can see where to find all bus stations in San Diego and Santa Ana, CA.

Service and Comfort on the bus from San Diego to Santa Ana, CA

Want to know which seat classes are available on the buses from San Diego to Santa Ana, CA? Or which bus companies serve the route San Diego to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the San Diego to Santa Ana, CA bus

How much does a San Diego Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $21 and takes 1h 55m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from San Diego to Santa Ana, CA?

This route is offered by 3 companies with a range of ticket prices between $21 and $39. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from San Diego to Santa Ana, CA each day?

Every day, the San Diego to Santa Ana, CA bus route is served by approximately 26 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Diego to Santa Ana, CA take?

The fastest bus from San Diego to Santa Ana, CA is offered by Greyhound US and takes 1h 45m. Bus tickets for this connection cost $23. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Diego to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from San Diego starts at 1:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Diego to Santa Ana, CA?

The latest bus trip departing from San Diego for Santa Ana, CA starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Diego Santa Ana, CA route?

When traveling by bus from San Diego to Santa Ana, CA, passengers can travel with Limousine Express, Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Diego and Santa Ana, CA?

You can check all the direct connections between San Diego and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Limousine Express, Greyhound US and FlixBus.

What can I take with me on the San Diego to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Diego Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Diego Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Diego to Santa Ana, CA on your planned travel date.

Available seat classes which are offered on the bus route San Diego to Santa Ana, CA

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Diego and to Santa Ana, CA

Here’s an overview of the most popular bus routes to San Diego and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!
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