Bus San Antonio, TX to San Diego - Compare all Companies

Compare all timetables for the bus from San Antonio, TX to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to San Diego from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today

$139

tomorrow

Tuesday

$197

Wednesday

$180

Thursday

Friday

$160

Saturday

$218

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$139	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/8/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/9/2026 5:45:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 37h 35m
FlixBus	46h 30m	9:15 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$139	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/8/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/10/2026 5:45:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 46h 30m
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$140	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/8/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 2/9/2026 10:15:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 42h 5m
Greyhound US	34h 0m	6:10 AM	San Antonio, TX	Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$140	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/8/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/9/2026 2:10:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 34h 0m
FlixBus	51h 0m	9:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$140	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/8/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 2/10/2026 10:15:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 51h 0m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	44h 0m	5:50 AM	San Antonio, TX	Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$197	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 2/10/2026 5:50:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/11/2026 11:50:00 PM. 50 Economy ticket for $197 per person are available. Travel duration is 44h 0m
Greyhound Lines Mexico	48h 20m	7:15 PM	San Antonio, TX	Bus Station	5:35 PM	San Diego	La Jolla Village	Economy	$199	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 2/10/2026 7:15:00 PM to La Jolla Village, San Diego (USA) arriving at 2/12/2026 5:35:00 PM. 50 Economy ticket for $199 per person are available. Travel duration is 48h 20m
FlixBus	45h 30m	6:10 PM	San Antonio, TX	Bus Station	1:40 PM	San Diego	La Jolla Village	Economy	$199	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/10/2026 6:10:00 PM to La Jolla Village, San Diego (USA) arriving at 2/12/2026 1:40:00 PM. 50 Economy ticket for $199 per person are available. Travel duration is 45h 30m
Greyhound Lines Mexico	53h 0m	7:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$200	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 2/10/2026 7:15:00 PM to Seaport Village, San Diego (USA) arriving at 2/12/2026 10:15:00 PM. 50 Economy ticket for $200 per person are available. Travel duration is 53h 0m
FlixBus	46h 0m	6:10 PM	San Antonio, TX	Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$201	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/10/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/12/2026 2:10:00 PM. 50 Economy ticket for $201 per person are available. Travel duration is 46h 0m

Did you know that if you travel from San Antonio, TX to San Diego via El Paso, TX, you can save more than $50? You can find the corresponding connections below.
- Busbud
  
  38h 10m
  
  0
  
  6:10 AM
  
  San Antonio, TX
  Bus Station
  
  3:35 PM
  
  El Paso, TX
  Bus Station
  
  0
  
  Economy
  
  $63
  
  A Bus from Busbud goes from Bus Station, San Antonio, TX (USA) at 2/9/2026 6:10:00 AM to Bus Station, El Paso, TX (USA) arriving at 2/9/2026 3:35:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 10h 25m
- FlixBus
  
  25h 30m
  
  0
  
  5:50 PM
  
  El Paso, TX
  Bus Station
  
  6:20 PM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $83
  
  A Bus from FlixBus goes from Bus Station, El Paso, TX (USA) at 2/9/2026 5:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/10/2026 6:20:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 25h 30m
Travel Time is 3h 50m shorter, and you will save $50

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	47h 5m	9:15 PM	San Antonio, TX	Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$180	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/11/2026 9:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/13/2026 6:20:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 47h 5m
FlixBus	42h 25m	6:10 PM	San Antonio, TX	Bus Station	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$181	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/11/2026 6:10:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/13/2026 10:35:00 AM. 50 Economy ticket for $181 per person are available. Travel duration is 42h 25m
Greyhound US	34h 30m	6:10 AM	San Antonio, TX	Bus Station	2:40 PM	San Diego	San Ysidro Transit Center	Economy	$182	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/11/2026 6:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 2/12/2026 2:40:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 34h 30m
Greyhound Lines Mexico	42h 25m	5:50 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$212	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 2/11/2026 5:50:00 AM to Seaport Village, San Diego (USA) arriving at 2/12/2026 10:15:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 42h 25m
Greyhound US	34h 0m	6:10 AM	San Antonio, TX	Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$212	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/11/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/12/2026 2:10:00 PM. 50 Economy ticket for $212 per person are available. Travel duration is 34h 0m

Did you know that if you travel from San Antonio, TX to San Diego via El Paso, TX, you can save more than $33? You can find the corresponding connections below.
- Busbud
  
  38h 10m
  
  0
  
  6:10 AM
  
  San Antonio, TX
  Bus Station
  
  3:35 PM
  
  El Paso, TX
  Bus Station
  
  0
  
  Economy
  
  $63
  
  A Bus from Busbud goes from Bus Station, San Antonio, TX (USA) at 2/9/2026 6:10:00 AM to Bus Station, El Paso, TX (USA) arriving at 2/9/2026 3:35:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 10h 25m
- FlixBus
  
  25h 30m
  
  0
  
  5:50 PM
  
  El Paso, TX
  Bus Station
  
  6:20 PM
  
  San Diego
  San Ysidro Transit Center
  
  0
  
  Economy
  
  $83
  
  A Bus from FlixBus goes from Bus Station, El Paso, TX (USA) at 2/9/2026 5:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 2/10/2026 6:20:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 25h 30m
Travel time is 6h 10m longer, but you will save $33

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	46h 30m	9:15 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$160	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/13/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/15/2026 5:45:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 46h 30m
FlixBus	51h 0m	9:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$161	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/13/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 2/15/2026 10:15:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 51h 0m
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$162	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/13/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 2/14/2026 10:15:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 42h 5m
FlixBus	46h 20m	9:15 PM	San Antonio, TX	Bus Station	5:35 PM	San Diego	La Jolla Village	Economy	$162	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/13/2026 9:15:00 PM to La Jolla Village, San Diego (USA) arriving at 2/15/2026 5:35:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 46h 20m
Greyhound US	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$164	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/13/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/14/2026 5:45:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 37h 35m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	46h 30m	9:15 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$218	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/14/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 2/16/2026 5:45:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 46h 30m
Greyhound US	33h 30m	6:10 AM	San Antonio, TX	Bus Station	1:40 PM	San Diego	La Jolla Village	Economy	$220	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/14/2026 6:10:00 AM to La Jolla Village, San Diego (USA) arriving at 2/15/2026 1:40:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 33h 30m
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$222	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/14/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 2/15/2026 10:15:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 42h 5m
Greyhound US	34h 0m	6:10 AM	San Antonio, TX	Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$222	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 2/14/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/15/2026 2:10:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 34h 0m
FlixBus	41h 55m	6:10 PM	San Antonio, TX	Bus Station	10:05 AM	San Diego	Seaport Village	Economy	$222	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 2/14/2026 6:10:00 PM to Seaport Village, San Diego (USA) arriving at 2/16/2026 10:05:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 41h 55m

Did you know that if you travel from San Antonio, TX to San Diego via El Paso, TX, you can save more than $72? You can find the corresponding connections below.
- Busbud
  
  37h 35m
  
  0
  
  6:10 AM
  
  San Antonio, TX
  Bus Station
  
  3:35 PM
  
  El Paso, TX
  Bus Station
  
  0
  
  Economy
  
  $63
  
  A Bus from Busbud goes from Bus Station, San Antonio, TX (USA) at 2/15/2026 6:10:00 AM to Bus Station, El Paso, TX (USA) arriving at 2/15/2026 3:35:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 10h 25m
- Busbud
  
  16h 45m
  
  0
  
  2:00 AM
  
  El Paso, TX
  Bus Station
  
  5:45 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $83
  
  A Bus from Busbud goes from Bus Station, El Paso, TX (USA) at 2/16/2026 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 2/16/2026 5:45:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 16h 45m
Travel time is 6h 5m longer, but you will save $72

Best Price Offer: The price for the cheapest bus from San Antonio, TX to San Diego is $134 on 2/16/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and San Diego

See here how frequent the connections between San Antonio, TX and San Diego are, during different times and days of the week.

Wednesday is the busiest day, with more than 15 daily buses from San Antonio, TX to San Diego. Sunday has instead the fewest connections, with only 9 daily coaches between San Antonio, TX and San Diego.

The busiest time of the day is the Evening, with 38 buses from San Antonio, TX to San Diego, while Night sees the fewest connections between San Antonio, TX and San Diego, with 8 offers.

Facts about the bus from San Antonio, TX to San Diego

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 12 times every day by bus from San Antonio, TX to San Diego in one click! Book your bus ticket from San Antonio, TX to San Diego starting from $134!

Cheapest Bus	$134
Fastest Bus	31h 30m
Earliest Bus	6:10 AM
Latest Bus	9:15 PM
Daily Bus Routes	12 Ø
Distance	1,126.5 miles
Bus Companies	FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from San Antonio, TX to San Diego

Every day, 12 buses from 3 bus companies leave San Antonio, TX for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/08/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 02/08

$139

Monday 02/09

Tuesday 02/10

$197

Wednesday 02/11

$212

Thursday 02/12

Friday 02/13

$160

Saturday 02/14

$218

Sunday 02/15

Monday 02/16

$134

Tuesday 02/17

Wednesday 02/18

Thursday 02/19

Friday 02/20

Saturday 02/21

Sunday 02/22

Monday 02/23

Tuesday 02/24

Wednesday 02/25

Thursday 02/26

Friday 02/27

Saturday 02/28

Sunday 03/01

Monday 03/02

Tuesday 03/03

Wednesday 03/04

Thursday 03/05

Friday 03/06

Saturday 03/07

The cheapest time to travel from San Antonio, TX to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to San Diego, for the next 30 days.

With a price starting from $139, Sunday is the cheapest day for a bus from San Antonio, TX to San Diego. Saturday instead is the most expensive day with prices starting from $218.

Night is the cheapest day time for bus tickets from San Antonio, TX to San Diego, with $134. Evening is the most expensive time of the day with prices starting from $139.

How to save money travelling from San Antonio, TX to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to San Diego are also emptier.

All bus stations and stops in San Antonio, TX and San Diego

In the map below, you can see where to find all bus stations in San Antonio, TX and San Diego.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from San Antonio, TX to San Diego

Want to know which seat classes are available on the buses from San Antonio, TX to San Diego? Or which bus companies serve the route San Antonio, TX to San Diego? Below you will find answers to your questions.

FAQs about the San Antonio, TX to San Diego bus

How much does a San Antonio, TX San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $134 and takes 35h 35m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to San Diego?

This route is offered by 3 companies with a range of ticket prices between $134 and $244. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Antonio, TX to San Diego each day?

Every day, the San Antonio, TX to San Diego bus route is served by approximately 12 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to San Diego take?

The fastest bus from San Antonio, TX to San Diego is offered by Greyhound US and takes 31h 30m. Bus tickets for this connection cost $141. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to San Diego?

The earliest bus arriving in San Diego from San Antonio, TX starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to San Diego?

The latest bus trip departing from San Antonio, TX for San Diego starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX San Diego route?

When traveling by bus from San Antonio, TX to San Diego, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and San Diego?

You can check all the direct connections between San Antonio, TX and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 12 daily trips between San Antonio, TX and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to San Diego?

Prices and availability for 12 trips between San Antonio, TX and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to San Diego

Here’s an overview of the most popular bus routes to San Antonio, TX and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!