Bus San Antonio, TX to San Diego - Compare all Companies

Compare all timetables for the bus from San Antonio, TX to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to San Diego from various bus operators like Greyhound US, Valley Transit or FlixBus for the next days.

today

$152

tomorrow

$141

Wednesday

$140

Thursday

$136

Friday

$133

Saturday

$136

Sunday

$140

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$152	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/21/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/22/2026 4:25:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 36h 15m
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$161	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/21/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 9/22/2026 10:15:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 42h 5m
Valley Transit	43h 35m	6:10 PM	San Antonio, TX	Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$167	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/21/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/23/2026 11:45:00 AM. 50 Economy ticket for $167 per person are available. Travel duration is 43h 35m
Valley Transit	43h 25m	6:10 PM	San Antonio, TX	Bus Station	11:35 AM	San Diego	Old Town Transit Center	Economy	$169	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/21/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/23/2026 11:35:00 AM. 50 Economy ticket for $169 per person are available. Travel duration is 43h 25m
FlixBus	45h 50m	9:55 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$183	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 9/21/2026 9:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/23/2026 5:45:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 45h 50m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$141	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/22/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/23/2026 4:25:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 36h 15m
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$148	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/22/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 9/23/2026 10:15:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 42h 5m
FlixBus	45h 50m	9:55 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$156	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 9/22/2026 9:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/24/2026 5:45:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 45h 50m
Valley Transit	43h 35m	6:10 PM	San Antonio, TX	Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$160	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/22/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/24/2026 11:45:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 43h 35m
Valley Transit	43h 25m	6:10 PM	San Antonio, TX	Bus Station	11:35 AM	San Diego	Old Town Transit Center	Economy	$169	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/22/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/24/2026 11:35:00 AM. 50 Economy ticket for $169 per person are available. Travel duration is 43h 25m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$140	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/23/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/24/2026 4:25:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 36h 15m
Greyhound US	35h 45m	6:10 AM	San Antonio, TX	Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$140	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/23/2026 6:10:00 AM to La Jolla Village, San Diego (USA) arriving at 9/24/2026 3:55:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 35h 45m
Greyhound Lines Mexico	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$143	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 9/23/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/24/2026 5:45:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 37h 35m
Greyhound Lines Mexico	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$144	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 9/23/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 9/24/2026 10:15:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 42h 5m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	37h 0m	6:10 AM	San Antonio, TX	Bus Station	5:10 PM	San Diego	San Ysidro Transit Center		Economy	$136	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/24/2026 6:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/25/2026 5:10:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 37h 0m
	Greyhound US	38h 10m	6:10 AM	San Antonio, TX	Bus Station	6:20 PM	San Diego	San Ysidro Transit Center		Economy	$138	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/24/2026 6:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/25/2026 6:20:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 38h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$133	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/25/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/26/2026 4:25:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 36h 15m
Greyhound US	38h 10m	6:10 AM	San Antonio, TX	Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$136	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/25/2026 6:10:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 9/26/2026 6:20:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 38h 10m
FlixBus	45h 50m	9:55 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$153	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 9/25/2026 9:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/27/2026 5:45:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 45h 50m
Valley Transit	42h 15m	6:10 PM	San Antonio, TX	Bus Station	10:25 AM	San Diego	Seaport Village	Economy	$159	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/25/2026 6:10:00 PM to Seaport Village, San Diego (USA) arriving at 9/27/2026 10:25:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 42h 15m
Valley Transit	41h 55m	6:10 PM	San Antonio, TX	Bus Station	10:05 AM	San Diego	Old Town Transit Center	Economy	$159	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/25/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/27/2026 10:05:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 41h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$136	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/26/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/27/2026 5:45:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 37h 35m
Valley Transit	43h 35m	6:10 PM	San Antonio, TX	Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$141	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/26/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/28/2026 11:45:00 AM. 50 Economy ticket for $141 per person are available. Travel duration is 43h 35m
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$143	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/26/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 9/27/2026 10:15:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 42h 5m
Valley Transit	43h 25m	6:10 PM	San Antonio, TX	Bus Station	11:35 AM	San Diego	Old Town Transit Center	Economy	$148	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 9/26/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/28/2026 11:35:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 43h 25m
FlixBus	45h 50m	9:55 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$159	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 9/26/2026 9:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/28/2026 5:45:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 45h 50m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$140	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/27/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/28/2026 4:25:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 36h 15m
Greyhound US	35h 45m	6:10 AM	San Antonio, TX	Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$140	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 9/27/2026 6:10:00 AM to La Jolla Village, San Diego (USA) arriving at 9/28/2026 3:55:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 35h 45m
Greyhound Lines Mexico	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$147	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 9/27/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 9/28/2026 10:15:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 42h 5m
Greyhound Lines Mexico	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$148	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 9/27/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/28/2026 5:45:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 37h 35m
FlixBus	43h 35m	6:10 PM	San Antonio, TX	Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$152	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 9/27/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/29/2026 11:45:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 43h 35m

Best Price Offer: The price for the cheapest bus from San Antonio, TX to San Diego is $132 on 10/16/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and San Diego

See here how frequent the connections between San Antonio, TX and San Diego are, during different times and days of the week.

Sunday is the busiest day, with more than 9 daily buses from San Antonio, TX to San Diego. Thursday has instead the fewest connections, with only 2 daily coaches between San Antonio, TX and San Diego.

The busiest time of the day is the Morning, with 23 buses from San Antonio, TX to San Diego, while Evening sees the fewest connections between San Antonio, TX and San Diego, with 21 offers.

Facts about the bus from San Antonio, TX to San Diego

Compare all providers like Greyhound US, Valley Transit and FlixBus that travel 6 times every day by bus from San Antonio, TX to San Diego in one click! Book your bus ticket from San Antonio, TX to San Diego starting from $132!

Cheapest Bus	$132
Fastest Bus	33h 45m
Earliest Bus	6:10 AM
Latest Bus	9:55 PM
Daily Bus Routes	6 Ø
Distance	1,126.5 miles
Bus Companies	Greyhound US, Valley Transit, FlixBus and Greyhound Lines Mexico

Cheapest bus connections from San Antonio, TX to San Diego

Every day, 6 buses from 4 bus companies leave San Antonio, TX for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/21/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 09/20

Monday 09/21

$152

Tuesday 09/22

$141

Wednesday 09/23

$140

Thursday 09/24

$136

Friday 09/25

$133

Saturday 09/26

$136

Sunday 09/27

$140

Monday 09/28

Tuesday 09/29

$145

Wednesday 09/30

$161

Thursday 10/01

$141

Friday 10/02

$149

Saturday 10/03

$150

Sunday 10/04

$141

Monday 10/05

$140

Tuesday 10/06

$152

Wednesday 10/07

$150

Thursday 10/08

$165

Friday 10/09

$136

Saturday 10/10

$153

Sunday 10/11

$150

Monday 10/12

$137

Tuesday 10/13

$134

Wednesday 10/14

$135

Thursday 10/15

Friday 10/16

$132

Saturday 10/17

The cheapest time to travel from San Antonio, TX to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to San Diego, for the next 30 days.

With a price starting from $128, Saturday is the cheapest day for a bus from San Antonio, TX to San Diego. Sunday instead is the most expensive day with prices starting from $140.

Morning is the cheapest day time for bus tickets from San Antonio, TX to San Diego, with $133. Evening is the most expensive time of the day with prices starting from $141.

How to save money travelling from San Antonio, TX to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to San Diego are also emptier.

Beloved bus companies from San Antonio, TX to San Diego

These are the most booked bus companies between San Antonio, TX to San Diego from our users.

Greyhound US from San Antonio, TX to San Diego

Here you will find the key facts about the Greyhound US bus route San Antonio, TX to San Diego:

Cheapest Price	$133
Fastest Bus	33h 45m
Earliest Bus	6:10 AM
Last Bus	6:10 AM
Daily Connections	2 Ø
Found on	8/27/2026

Valley Transit from San Antonio, TX to San Diego

Here you will find the key facts about the Valley Transit bus route San Antonio, TX to San Diego:

Cheapest Price	$141
Fastest Bus	39h 55m
Earliest Bus	6:10 PM
Last Bus	6:10 PM
Daily Connections	3 Ø
Found on	8/26/2026

FlixBus from San Antonio, TX to San Diego

Here you will find the key facts about the FlixBus bus route San Antonio, TX to San Diego:

Cheapest Price	$152
Fastest Bus	41h 5m
Earliest Bus	9:55 PM
Last Bus	9:55 PM
Daily Connections	1 Ø
Found on	8/27/2026

All bus stations and stops in San Antonio, TX and San Diego

In the map below, you can see where to find all bus stations in San Antonio, TX and San Diego.

Bus Station

N St Mary's St 500

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

La Cantera

La Cantera Pkwy 15900

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

Downtown

Service and Comfort on the bus from San Antonio, TX to San Diego

Want to know which seat classes are available on the buses from San Antonio, TX to San Diego? Or which bus companies serve the route San Antonio, TX to San Diego? Below you will find answers to your questions.

FAQs about the San Antonio, TX to San Diego bus

How much does a San Antonio, TX San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $132 and takes 34h 15m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to San Diego?

This route is offered by 4 companies with a range of ticket prices between $132 and $183. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Antonio, TX to San Diego each day?

Every day, the San Antonio, TX to San Diego bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to San Diego take?

The fastest bus from San Antonio, TX to San Diego is offered by Greyhound US and takes 33h 45m. Bus tickets for this connection cost $140. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to San Diego?

The earliest bus arriving in San Diego from San Antonio, TX starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to San Diego?

The latest bus trip departing from San Antonio, TX for San Diego starts at 9:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX San Diego route?

When traveling by bus from San Antonio, TX to San Diego, passengers can travel with Greyhound US, Valley Transit and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and San Diego?

You can check all the direct connections between San Antonio, TX and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, Valley Transit and FlixBus.

What can I take with me on the San Antonio, TX to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between San Antonio, TX and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to San Diego?

Prices and availability for 6 trips between San Antonio, TX and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to San Diego

Here’s an overview of the most popular bus routes to San Antonio, TX and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!