Bus from San Antonio, TX to San Diego from $109

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from San Antonio, TX to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to San Diego from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today
from $127
tomorrow
from $198
Tuesday
from $109
Wednesday
from $139
Thursday
from $140
Friday
Saturday
from $322

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    35h 35m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $127
  • FlixBus
    48h 30m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    9:30 PM
    San Diego
    Seaport Village
    0
    FlixBus
    Economy
    $134
  • FlixBus
    45h 10m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $136
  • FlixBus
    44h 45m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $137
  • Greyhound US
    39h 20m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $152

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    35h 35m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    5:45 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $198
  • FlixBus
    38h 55m
    0
    6:20 PM
    San Antonio, TX
    Bus Station
    9:15 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $202
  • FlixBus
    38h 25m
    0
    6:20 PM
    San Antonio, TX
    Bus Station
    8:45 AM
    San Diego
    La Jolla Village
    0
    FlixBus
    Economy
    $202
  • Greyhound Lines Mexico
    46h 20m
    0
    7:15 PM
    San Antonio, TX
    Bus Station
    5:35 PM
    San Diego
    La Jolla Village
    0
    Greyhound Lines Mexico
    Economy
    $204
  • Greyhound Lines Mexico
    46h 55m
    0
    7:15 PM
    San Antonio, TX
    Bus Station
    6:10 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $206

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    37h 15m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    7:25 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $109
  • Greyhound Lines Mexico
    41h 45m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $133
  • Greyhound US
    39h 20m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    9:30 PM
    San Diego
    Seaport Village
    0
    Greyhound US
    Economy
    $133
  • FlixBus
    39h 10m
    0
    6:20 PM
    San Antonio, TX
    Bus Station
    9:30 AM
    San Diego
    Old Town Transit Center
    0
    FlixBus
    Economy
    $136
  • FlixBus
    40h 20m
    0
    6:20 PM
    San Antonio, TX
    Bus Station
    10:40 AM
    San Diego
    Balboa Park
    0
    FlixBus
    Economy
    $136

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    39h 45m
    0
    6:20 PM
    San Antonio, TX
    Bus Station
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $139
  • FlixBus
    45h 20m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $139
  • Greyhound US
    34h 0m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    4:10 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $172
  • Greyhound US
    33h 10m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    3:20 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound US
    Economy
    $205
  • Greyhound Lines Mexico
    41h 45m
    0
    6:05 AM
    San Antonio, TX
    Bus Station
    11:50 PM
    San Diego
    Old Town Transit Center
    0
    Greyhound Lines Mexico
    Economy
    $223

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    45h 20m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $140
  • FlixBus
    39h 45m
    0
    6:20 PM
    San Antonio, TX
    Bus Station
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $152
  • Greyhound US
    34h 0m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    4:10 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $159

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    45h 20m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    6:20 PM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $322
  • Greyhound US
    34h 0m
    0
    6:10 AM
    San Antonio, TX
    Bus Station
    4:10 PM
    San Diego
    San Ysidro Transit Center
    0
    Greyhound US
    Economy
    $332
  • FlixBus
    39h 45m
    0
    6:20 PM
    San Antonio, TX
    Bus Station
    10:05 AM
    San Diego
    San Ysidro Transit Center
    0
    FlixBus
    Economy
    $351
  • Did you know that if you travel from San Antonio, TX to San Diego via Las Cruces, NM, you can save more than $175? You can find the corresponding connections below.
    • FlixBus
      50h 35m
      0
      6:10 AM
      San Antonio, TX
      Bus Station
      5:55 PM
      Las Cruces, NM
      Mesilla Valley Intermodal Transit Terminal
      0
      FlixBus
      Economy
      $79
      • Waiting Time 16h 55m
    • FlixBus
      21h 55m
      0
      10:50 AM
      Las Cruces, NM
      Mesilla Valley Intermodal Transit Terminal
      8:45 AM
      San Diego
      La Jolla Village
      0
      FlixBus
      Economy
      $68
    Travel time is 16h 35m longer, but you will save $175

Frequency of bus connections between San Antonio, TX and San Diego

See here how frequent the connections between San Antonio, TX and San Diego are, during different times and days of the week.
Tuesday is the busiest day, with more than 20 daily buses from San Antonio, TX to San Diego. Thursday has instead the fewest connections, with only 3 daily coaches between San Antonio, TX and San Diego.
The busiest time of the day is the Evening, with 41 buses from San Antonio, TX to San Diego, while Night sees the fewest connections between San Antonio, TX and San Diego, with 5 offers.

Facts about the bus from San Antonio, TX to San Diego

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 11 times every day by bus from San Antonio, TX to San Diego in one click! Book your bus ticket from San Antonio, TX to San Diego starting from $109!

Cheapest Bus $109
Fastest Bus 32h 40m
Earliest Bus 6:10 AM
Latest Bus 9:00 PM
Daily Bus Routes 11 Ø
Distance 1,126.5 miles
Bus Companies FlixBus, Greyhound US, Greyhound Lines Mexico and Valley Transit

Cheapest bus connections from San Antonio, TX to San Diego

Every day, 11 buses from 4 bus companies leave San Antonio, TX for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/29/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/29
$181
Monday 06/30
$247
Tuesday 07/01
$109
Wednesday 07/02
$172
Thursday 07/03
$140
Friday 07/04
Saturday 07/05
$322
Sunday 07/06
$186
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
$153
Saturday 07/12
Sunday 07/13
Monday 07/14
Tuesday 07/15
Wednesday 07/16
Thursday 07/17
Friday 07/18
Saturday 07/19
Sunday 07/20
Monday 07/21
Tuesday 07/22
Wednesday 07/23
Thursday 07/24
Friday 07/25
Saturday 07/26

The cheapest time to travel from San Antonio, TX to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to San Diego, for the next 30 days.
With a price starting from $109, Tuesday is the cheapest day for a bus from San Antonio, TX to San Diego. Saturday instead is the most expensive day with prices starting from $322.
Morning is the cheapest day time for bus tickets from San Antonio, TX to San Diego, with $109. Night is the most expensive time of the day with prices starting from $148.

How to save money travelling from San Antonio, TX to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to San Diego are also emptier.

All bus stations and stops in San Antonio, TX and San Diego

In the map below, you can see where to find all bus stations in San Antonio, TX and San Diego.

Service and Comfort on the bus from San Antonio, TX to San Diego

Want to know which seat classes are available on the buses from San Antonio, TX to San Diego? Or which bus companies serve the route San Antonio, TX to San Diego? Below you will find answers to your questions.

FAQs about the San Antonio, TX to San Diego bus

How much does a San Antonio, TX San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $109 and takes 37h 15m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to San Diego?

This route is offered by 4 companies with a range of ticket prices between $109 and $351. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Antonio, TX to San Diego each day?

Every day, the San Antonio, TX to San Diego bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to San Diego take?

The fastest bus from San Antonio, TX to San Diego is offered by Greyhound US and takes 32h 40m. Bus tickets for this connection cost $162. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to San Diego?

The earliest bus arriving in San Diego from San Antonio, TX starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to San Diego?

The latest bus trip departing from San Antonio, TX for San Diego starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX San Diego route?

When traveling by bus from San Antonio, TX to San Diego, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and San Diego?

You can check all the direct connections between San Antonio, TX and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to San Diego on your planned travel date.

Available seat classes which are offered on the bus route San Antonio, TX to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to San Diego

Here’s an overview of the most popular bus routes to San Antonio, TX and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to San Antonio, TX from Piedras Negras Buses to San Antonio, TX from Piedras Negras
Buses Plano, TX to San Antonio, TX Buses Plano, TX to San Antonio, TX
Buses from Temple, TX to San Antonio, TX Buses from Temple, TX to San Antonio, TX
Buses Las Vegas - San Antonio, TX Buses Las Vegas - San Antonio, TX
Buses Houston to San Diego Buses Houston to San Diego
Bus to San Diego from Santa Ana, CA Bus to San Diego from Santa Ana, CA
Bus from New York to San Diego Bus from New York to San Diego
Dallas to San Diego bus Dallas to San Diego bus
Popular Airport Shuttles to San Antonio, TX and to San Diego
CheckMyBus › Buses in USA › Bus to San Antonio, TX › Bus to San Diego

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus offers, we and our partners use technical, analytical, and marketing cookies to personalize the ads. We remember your anonymized details to provide a personalized experience.