Bus San Antonio, TX to San Diego - Compare all Companies

Compare all timetables for the bus from San Antonio, TX to San Diego

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to San Diego from various bus operators like Valley Transit, Greyhound US or Greyhound Lines Mexico for the next days.

today

tomorrow

$121

Saturday

$128

Sunday

$104

Monday

$115

Tuesday

$117

Wednesday

$112

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$121	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 5/9/2026 10:15:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 42h 5m
Greyhound US	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$121	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/9/2026 5:45:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 37h 35m
Valley Transit	51h 0m	9:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$121	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 5/10/2026 10:15:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 51h 0m
Valley Transit	46h 30m	9:15 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$121	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/10/2026 5:45:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 46h 30m
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$123	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/8/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/9/2026 4:25:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 36h 15m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$128	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/9/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 5/10/2026 10:15:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 42h 5m
Greyhound US	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$128	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/9/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/10/2026 5:45:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 37h 35m
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$129	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/9/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/10/2026 4:25:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 36h 15m
Valley Transit	51h 0m	9:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$129	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/9/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 5/11/2026 10:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 51h 0m
Valley Transit	46h 30m	9:15 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$129	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/9/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/11/2026 5:45:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 46h 30m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$104	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/10/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 5/11/2026 10:15:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 42h 5m
Greyhound US	34h 0m	6:10 AM	San Antonio, TX	Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$104	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/10/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/11/2026 2:10:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 34h 0m
Valley Transit	46h 30m	9:15 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$104	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/10/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/12/2026 5:45:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 46h 30m
Valley Transit	41h 55m	6:10 PM	San Antonio, TX	Bus Station	10:05 AM	San Diego	Seaport Village	Economy	$105	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/10/2026 6:10:00 PM to Seaport Village, San Diego (USA) arriving at 5/12/2026 10:05:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 41h 55m
FlixBus	47h 5m	9:15 PM	San Antonio, TX	Bus Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$105	A Bus from FlixBus goes from Bus Station, San Antonio, TX (USA) at 5/10/2026 9:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 5/12/2026 6:20:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 47h 5m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	42h 5m	6:10 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$115	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/11/2026 6:10:00 AM to Seaport Village, San Diego (USA) arriving at 5/12/2026 10:15:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 42h 5m
Greyhound US	37h 35m	6:10 AM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$115	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/11/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/12/2026 5:45:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 37h 35m
Greyhound Lines Mexico	48h 55m	7:15 PM	San Antonio, TX	Bus Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$115	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/11/2026 7:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/13/2026 6:10:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 48h 55m
Greyhound Lines Mexico	53h 0m	7:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$117	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/11/2026 7:15:00 PM to Seaport Village, San Diego (USA) arriving at 5/13/2026 10:15:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 53h 0m
Valley Transit	43h 35m	6:10 PM	San Antonio, TX	Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$117	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/11/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/13/2026 11:45:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 43h 35m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	48h 55m	7:15 PM	San Antonio, TX	Bus Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$117	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/12/2026 7:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/14/2026 6:10:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 48h 55m
Greyhound Lines Mexico	53h 0m	7:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$118	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/12/2026 7:15:00 PM to Seaport Village, San Diego (USA) arriving at 5/14/2026 10:15:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 53h 0m
Greyhound Lines Mexico	42h 40m	1:30 AM	San Antonio, TX	Bus Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$119	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/12/2026 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/13/2026 6:10:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 42h 40m
Valley Transit	43h 35m	6:10 PM	San Antonio, TX	Bus Station	11:45 AM	San Diego	Old Town Transit Center	Economy	$120	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/12/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/14/2026 11:45:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 43h 35m
Valley Transit	46h 0m	6:10 PM	San Antonio, TX	Bus Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$120	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/12/2026 6:10:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/14/2026 2:10:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 46h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	46h 30m	9:15 PM	San Antonio, TX	Bus Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$112	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/13/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 5/15/2026 5:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 46h 30m
Valley Transit	51h 0m	9:15 PM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$113	A Bus from Valley Transit goes from Bus Station, San Antonio, TX (USA) at 5/13/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 5/15/2026 10:15:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 51h 0m
Greyhound US	36h 15m	6:10 AM	San Antonio, TX	Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$115	A Bus from Greyhound US goes from Bus Station, San Antonio, TX (USA) at 5/13/2026 6:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/14/2026 4:25:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 36h 15m
Greyhound Lines Mexico	42h 25m	5:50 AM	San Antonio, TX	Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$117	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/13/2026 5:50:00 AM to Seaport Village, San Diego (USA) arriving at 5/14/2026 10:15:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 42h 25m
Greyhound Lines Mexico	44h 0m	5:50 AM	San Antonio, TX	Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$118	A Bus from Greyhound Lines Mexico goes from Bus Station, San Antonio, TX (USA) at 5/13/2026 5:50:00 AM to Old Town Transit Center, San Diego (USA) arriving at 5/14/2026 11:50:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 44h 0m

Best Price Offer: The price for the cheapest bus from San Antonio, TX to San Diego is $104 on 5/10/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between San Antonio, TX and San Diego

See here how frequent the connections between San Antonio, TX and San Diego are, during different times and days of the week.

Wednesday is the busiest day, with more than 15 daily buses from San Antonio, TX to San Diego. Tuesday has instead the fewest connections, with only 6 daily coaches between San Antonio, TX and San Diego.

The busiest time of the day is the Evening, with 35 buses from San Antonio, TX to San Diego, while Night sees the fewest connections between San Antonio, TX and San Diego, with 6 offers.

Facts about the bus from San Antonio, TX to San Diego

Compare all providers like Valley Transit, Greyhound US and Greyhound Lines Mexico that travel 10 times every day by bus from San Antonio, TX to San Diego in one click! Book your bus ticket from San Antonio, TX to San Diego starting from $104!

Cheapest Bus	$104
Fastest Bus	32h 0m
Earliest Bus	6:10 AM
Latest Bus	9:15 PM
Daily Bus Routes	10 Ø
Distance	1,126.5 miles
Bus Companies	Valley Transit, Greyhound US, Greyhound Lines Mexico and FlixBus

Cheapest bus connections from San Antonio, TX to San Diego

Every day, 10 buses from 4 bus companies leave San Antonio, TX for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$121

Saturday 05/09

$128

Sunday 05/10

$105

Monday 05/11

$115

Tuesday 05/12

$117

Wednesday 05/13

$112

Thursday 05/14

$106

Friday 05/15

$115

Saturday 05/16

$108

Sunday 05/17

$105

Monday 05/18

$111

Tuesday 05/19

$126

Wednesday 05/20

$128

Thursday 05/21

$132

Friday 05/22

$128

Saturday 05/23

$135

Sunday 05/24

$124

Monday 05/25

$120

Tuesday 05/26

$124

Wednesday 05/27

$128

Thursday 05/28

$130

Friday 05/29

$129

Saturday 05/30

The cheapest time to travel from San Antonio, TX to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to San Diego, for the next 30 days.

With a price starting from $104, Sunday is the cheapest day for a bus from San Antonio, TX to San Diego. Tuesday instead is the most expensive day with prices starting from $117.

Morning is the cheapest day time for bus tickets from San Antonio, TX to San Diego, with $104. Night is the most expensive time of the day with prices starting from $105.

How to save money travelling from San Antonio, TX to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to San Diego are also emptier.

Beloved bus companies from San Antonio, TX to San Diego

These are the most booked bus companies between San Antonio, TX to San Diego from our users.

Valley Transit from San Antonio, TX to San Diego

Here you will find the key facts about the Valley Transit bus route San Antonio, TX to San Diego:

Cheapest Price	$104
Fastest Bus	39h 55m
Earliest Bus	6:10 PM
Last Bus	9:15 PM
Daily Connections	4 Ø
Found on	5/1/2026

FlixBus from San Antonio, TX to San Diego

Here you will find the key facts about the FlixBus bus route San Antonio, TX to San Diego:

Cheapest Price	$105
Fastest Bus	42h 10m
Earliest Bus	6:10 PM
Last Bus	9:00 PM
Daily Connections	2 Ø
Found on	5/1/2026

All bus stations and stops in San Antonio, TX and San Diego

In the map below, you can see where to find all bus stations in San Antonio, TX and San Diego.

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from San Antonio, TX to San Diego

Want to know which seat classes are available on the buses from San Antonio, TX to San Diego? Or which bus companies serve the route San Antonio, TX to San Diego? Below you will find answers to your questions.

FAQs about the San Antonio, TX to San Diego bus

How much does a San Antonio, TX San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $104 and takes 40h 5m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to San Diego?

This route is offered by 4 companies with a range of ticket prices between $104 and $175. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from San Antonio, TX to San Diego each day?

Every day, the San Antonio, TX to San Diego bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to San Diego take?

The fastest bus from San Antonio, TX to San Diego is offered by Greyhound US and takes 32h 0m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to San Diego?

The earliest bus arriving in San Diego from San Antonio, TX starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to San Diego?

The latest bus trip departing from San Antonio, TX for San Diego starts at 9:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX San Diego route?

When traveling by bus from San Antonio, TX to San Diego, passengers can travel with Valley Transit, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and San Diego?

You can check all the direct connections between San Antonio, TX and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Valley Transit, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between San Antonio, TX and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to San Diego?

Prices and availability for 10 trips between San Antonio, TX and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to San Diego

Here’s an overview of the most popular bus routes to San Antonio, TX and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!