Which bus from Portland, OR to San Diego is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $105
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Portland, OR to San Diego

Here is a selection of the cheapest bus trips from the schedule from Portland, OR to San Diego from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
$141
Monday
$112
Tuesday
$115
Wednesday
Thursday
Friday
$115

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 28h 25m 8:00 PM Portland, OR Union Bus Station 12:25 AM San Diego San Ysidro Transit Center  Economy $141
FlixBus 45h 50m 8:00 PM Portland, OR Union Bus Station 5:50 PM San Diego San Ysidro Transit Center  Economy $141
Greyhound US 38h 25m 2:00 AM Portland, OR Greyhound Bus Station 4:25 PM San Diego Old Town Transit Center  Economy $142
FlixBus 27h 50m 8:00 PM Portland, OR Greyhound Bus Station 11:50 PM San Diego Old Town Transit Center  Economy $142
Greyhound US 44h 15m 2:00 AM Portland, OR Greyhound Bus Station 10:15 PM San Diego Seaport Village  Economy $147

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 38h 25m 2:00 AM Portland, OR Greyhound Bus Station 4:25 PM San Diego Old Town Transit Center  Economy $112
FlixBus 44h 25m 8:00 PM Portland, OR Greyhound Bus Station 4:25 PM San Diego Old Town Transit Center  Economy $112
FlixBus 27h 50m 8:00 PM Portland, OR Greyhound Bus Station 11:50 PM San Diego Old Town Transit Center  Economy $113
FlixBus 50h 15m 8:00 PM Portland, OR Greyhound Bus Station 10:15 PM San Diego Seaport Village  Economy $114
Greyhound US 44h 15m 2:00 AM Portland, OR Greyhound Bus Station 10:15 PM San Diego Seaport Village  Economy $116

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 50m 8:00 PM Portland, OR Greyhound Bus Station 11:50 PM San Diego Old Town Transit Center  Economy $115
Greyhound US 38h 25m 2:00 AM Portland, OR Greyhound Bus Station 4:25 PM San Diego Old Town Transit Center  Economy $116
FlixBus 44h 25m 8:00 PM Portland, OR Greyhound Bus Station 4:25 PM San Diego Old Town Transit Center  Economy $116
Greyhound US 44h 15m 2:00 AM Portland, OR Greyhound Bus Station 10:15 PM San Diego Seaport Village  Economy $118
FlixBus 50h 15m 8:00 PM Portland, OR Greyhound Bus Station 10:15 PM San Diego Seaport Village  Economy $119

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 38h 25m 2:00 AM Portland, OR Greyhound Bus Station 4:25 PM San Diego Old Town Transit Center  Economy $115
FlixBus 27h 50m 8:00 PM Portland, OR Greyhound Bus Station 11:50 PM San Diego Old Town Transit Center  Economy $115
FlixBus 44h 25m 8:00 PM Portland, OR Greyhound Bus Station 4:25 PM San Diego Old Town Transit Center  Economy $115
Greyhound US 44h 15m 2:00 AM Portland, OR Greyhound Bus Station 10:15 PM San Diego Seaport Village  Economy $118
FlixBus 50h 15m 8:00 PM Portland, OR Greyhound Bus Station 10:15 PM San Diego Seaport Village  Economy $119

Best Price Offer: The price for the cheapest bus from Portland, OR to San Diego is $105 on 3/29/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Portland, OR and San Diego

See here how frequent the connections between Portland, OR and San Diego are, during different times and days of the week.
Sunday is the busiest day, with more than 14 daily buses from Portland, OR to San Diego. Monday has instead the fewest connections, with only 5 daily coaches between Portland, OR and San Diego.
The busiest time of the day is the Evening, with 18 buses from Portland, OR to San Diego, while Night sees the fewest connections between Portland, OR and San Diego, with 11 offers.

Facts about the bus from Portland, OR to San Diego

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from Portland, OR to San Diego in one click! Book your bus ticket from Portland, OR to San Diego starting from $105!

Cheapest Bus $105
Fastest Bus 27h 50m
Earliest Bus 2:00 AM
Latest Bus 8:00 PM
Daily Bus Routes 7 Ø
Distance 932.4 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Portland, OR to San Diego

Every day, 7 buses from 2 bus companies leave Portland, OR for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/15
Monday 03/16
Tuesday 03/17
Wednesday 03/18
Thursday 03/19
Friday 03/20
Saturday 03/21
$118
Sunday 03/22
$141
Monday 03/23
$112
Tuesday 03/24
$115
Wednesday 03/25
Thursday 03/26
Friday 03/27
$115
Saturday 03/28
$119
Sunday 03/29
$105
Monday 03/30
Tuesday 03/31
$119
Wednesday 04/01
Thursday 04/02
$105
Friday 04/03
Saturday 04/04
$109
Sunday 04/05
$106
Monday 04/06
$113
Tuesday 04/07
$139
Wednesday 04/08
$143
Thursday 04/09
$122
Friday 04/10
$124
Saturday 04/11

The cheapest time to travel from Portland, OR to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Portland, OR to San Diego, for the next 30 days.
With a price starting from $100, Monday is the cheapest day for a bus from Portland, OR to San Diego. Friday instead is the most expensive day with prices starting from $115.
Night is the cheapest day time for bus tickets from Portland, OR to San Diego, with $100. Evening is the most expensive time of the day with prices starting from $112.

How to save money travelling from Portland, OR to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Portland, OR to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Portland, OR to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Portland, OR to San Diego are also emptier.

Beloved bus companies from Portland, OR to San Diego

These are the most booked bus companies between Portland, OR to San Diego from our users.

FlixBus from Portland, OR to San Diego

FlixBus

Here you will find the key facts about the FlixBus bus route Portland, OR to San Diego:

Cheapest Price $112
Fastest Bus 27h 50m
Earliest Bus 8:00 PM
Last Bus 8:00 PM
Daily Connections 4 Ø
Found on 3/6/2026

All bus stations and stops in Portland, OR and San Diego

In the map below, you can see where to find all bus stations in Portland, OR and San Diego.

Service and Comfort on the bus from Portland, OR to San Diego

Want to know which seat classes are available on the buses from Portland, OR to San Diego? Or which bus companies serve the route Portland, OR to San Diego? Below you will find answers to your questions.

FAQs about the Portland, OR to San Diego bus

How much does a Portland, OR San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $105 and takes 38h 25m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Portland, OR to San Diego?

This route is offered by 2 companies with a range of ticket prices between $105 and $159. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Portland, OR to San Diego each day?

Every day, the Portland, OR to San Diego bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Portland, OR to San Diego take?

The fastest bus from Portland, OR to San Diego is offered by FlixBus and takes 27h 50m. Bus tickets for this connection cost $146. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Portland, OR to San Diego?

The earliest bus arriving in San Diego from Portland, OR starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Portland, OR to San Diego?

The latest bus trip departing from Portland, OR for San Diego starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Portland, OR San Diego route?

When traveling by bus from Portland, OR to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Portland, OR and San Diego?

You can check all the direct connections between Portland, OR and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Portland, OR to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Portland, OR San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Portland, OR San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Portland, OR to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Portland, OR to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Portland, OR and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Portland, OR to San Diego?

Prices and availability for 7 trips between Portland, OR and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Portland, OR to San Diego

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Portland, OR and to San Diego

Here’s an overview of the most popular bus routes to Portland, OR and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!
From Irvine, CA to Portland, OR bus From Irvine, CA to Portland, OR bus
Albany, NY to Portland, OR bus Albany, NY to Portland, OR bus
Bus Turlock, CA - Portland, OR Bus Turlock, CA - Portland, OR
Bus Modesto, CA - Portland, OR Bus Modesto, CA - Portland, OR
Buses from Raleigh, NC to San Diego Buses from Raleigh, NC to San Diego
Bus from Monterrey, NL to San Diego Bus from Monterrey, NL to San Diego
Buses Selma, CA - San Diego Buses Selma, CA - San Diego
Buses San Fernando, CA to San Diego Buses San Fernando, CA to San Diego
Popular Airport Shuttles to Portland, OR and to San Diego
CheckMyBus › Buses in USA › Bus to Portland, OR › Bus to San Diego

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.