Bus Portland, OR to San Diego - Compare all Companies

Compare all timetables for the bus from Portland, OR to San Diego

Here is a selection of the cheapest bus trips from the schedule from Portland, OR to San Diego from various bus operators like FlixBus or Greyhound US for the next days.

today

$162

tomorrow

$210

Friday

Saturday

$373

Sunday

$259

Monday

Tuesday

$207

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	28h 35m	7:50 PM	Portland, OR	Union Bus Station	12:25 AM	San Diego	San Ysidro Transit Center		Economy	$162	A Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/17/2025 7:50:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/19/2025 12:25:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 28h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	44h 15m	2:00 AM	Portland, OR	Union Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$210	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/18/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/19/2025 10:15:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 44h 15m
Greyhound US	38h 25m	2:00 AM	Portland, OR	Union Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$211	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/18/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/19/2025 4:25:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 38h 25m
Greyhound US	37h 55m	2:00 AM	Portland, OR	Union Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$211	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/18/2025 2:00:00 AM to La Jolla Village, San Diego (USA) arriving at 12/19/2025 3:55:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 37h 55m
FlixBus	50h 15m	8:00 PM	Portland, OR	Union Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$231	A Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/18/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/20/2025 10:15:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 50h 15m
FlixBus	44h 25m	8:00 PM	Portland, OR	Union Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$234	A Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/18/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/20/2025 4:25:00 PM. 50 Economy ticket for $234 per person are available. Travel duration is 44h 25m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	38h 25m	2:00 AM	Portland, OR	Greyhound Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$373	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/21/2025 4:25:00 PM. 50 Economy ticket for $373 per person are available. Travel duration is 38h 25m
Greyhound US	44h 15m	2:00 AM	Portland, OR	Greyhound Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$374	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/21/2025 10:15:00 PM. 50 Economy ticket for $374 per person are available. Travel duration is 44h 15m
FlixBus	27h 50m	8:00 PM	Portland, OR	Greyhound Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$418	A Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/21/2025 11:50:00 PM. 50 Economy ticket for $418 per person are available. Travel duration is 27h 50m
FlixBus	44h 25m	8:00 PM	Portland, OR	Greyhound Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$418	A Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 4:25:00 PM. 50 Economy ticket for $418 per person are available. Travel duration is 44h 25m
FlixBus	50h 15m	8:00 PM	Portland, OR	Greyhound Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$420	A Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/20/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $420 per person are available. Travel duration is 50h 15m

Did you know that if you travel from Portland, OR to San Diego via Santa Ana, CA, you can save more than $74? You can find the corresponding connections below.
- FlixBus
  
  27h 50m
  
  0
  
  8:00 PM
  
  Portland, OR
  Union Bus Station
  
  10:00 PM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $267
  
  A Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/18/2025 8:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 12/19/2025 10:00:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 26h 0m
- Busbud
  
  1h 45m
  
  0
  
  10:05 PM
  
  Santa Ana, CA
  Bus Stop
  
  11:50 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $32
  
  A Bus from Busbud goes from Bus Stop, Santa Ana, CA (USA) at 12/19/2025 10:05:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/19/2025 11:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 1h 45m
Travel time is the same as the direct connection, but you will save $74

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	27h 50m	8:00 PM	Portland, OR	Greyhound Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$259	A Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 11:50:00 PM. 50 Economy ticket for $259 per person are available. Travel duration is 27h 50m
Greyhound US	44h 15m	2:00 AM	Portland, OR	Greyhound Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$260	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/22/2025 10:15:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 44h 15m
Greyhound US	38h 25m	2:00 AM	Portland, OR	Greyhound Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$260	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/22/2025 4:25:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 38h 25m
FlixBus	50h 15m	8:00 PM	Portland, OR	Greyhound Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$261	A Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 12/21/2025 8:00:00 PM to Seaport Village, San Diego (USA) arriving at 12/23/2025 10:15:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 50h 15m
Greyhound US	37h 55m	2:00 AM	Portland, OR	Union Bus Station	3:55 PM	San Diego	La Jolla Village	Economy	$262	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/21/2025 2:00:00 AM to La Jolla Village, San Diego (USA) arriving at 12/22/2025 3:55:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 37h 55m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 25m	8:00 PM	Portland, OR	Union Bus Station	12:25 AM	San Diego	San Ysidro Transit Center	Economy	$207	A Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 8:00:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/25/2025 12:25:00 AM. 50 Economy ticket for $207 per person are available. Travel duration is 28h 25m
Greyhound US	34h 20m	2:00 AM	Portland, OR	Union Bus Station	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$262	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/24/2025 12:20:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 34h 20m
Greyhound US	44h 15m	2:00 AM	Portland, OR	Union Bus Station	10:15 PM	San Diego	Seaport Village	Economy	$363	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to Seaport Village, San Diego (USA) arriving at 12/24/2025 10:15:00 PM. 50 Economy ticket for $363 per person are available. Travel duration is 44h 15m
FlixBus	27h 50m	8:00 PM	Portland, OR	Union Bus Station	11:50 PM	San Diego	Old Town Transit Center	Economy	$372	A Bus from FlixBus goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 8:00:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/24/2025 11:50:00 PM. 50 Economy ticket for $372 per person are available. Travel duration is 27h 50m
Greyhound US	38h 25m	2:00 AM	Portland, OR	Union Bus Station	4:25 PM	San Diego	Old Town Transit Center	Economy	$373	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 12/23/2025 2:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/24/2025 4:25:00 PM. 50 Economy ticket for $373 per person are available. Travel duration is 38h 25m

Best Price Offer: The price for the cheapest bus from Portland, OR to San Diego is $153 on 12/25/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Portland, OR and San Diego

See here how frequent the connections between Portland, OR and San Diego are, during different times and days of the week.

Sunday is the busiest day, with more than 13 daily buses from Portland, OR to San Diego. Wednesday has instead the fewest connections, with only 1 daily coaches between Portland, OR and San Diego.

The busiest time of the day is the Evening, with 20 buses from Portland, OR to San Diego, while Night sees the fewest connections between Portland, OR and San Diego, with 15 offers.

Facts about the bus from Portland, OR to San Diego

Compare all providers like FlixBus and Greyhound US that travel 7 times every day by bus from Portland, OR to San Diego in one click! Book your bus ticket from Portland, OR to San Diego starting from $153!

Cheapest Bus	$153
Fastest Bus	27h 50m
Earliest Bus	7:50 PM
Latest Bus	8:00 PM
Daily Bus Routes	7 Ø
Distance	932.4 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Portland, OR to San Diego

Every day, 7 buses from 2 bus companies leave Portland, OR for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

$161

Thursday 12/18

$210

Friday 12/19

Saturday 12/20

$373

Sunday 12/21

$262

Monday 12/22

Tuesday 12/23

$363

Wednesday 12/24

$157

Thursday 12/25

$153

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

$183

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

The cheapest time to travel from Portland, OR to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Portland, OR to San Diego, for the next 30 days.

With a price starting from $153, Thursday is the cheapest day for a bus from Portland, OR to San Diego. Sunday instead is the most expensive day with prices starting from $259.

Night is the cheapest day time for bus tickets from Portland, OR to San Diego, with $153. Evening is the most expensive time of the day with prices starting from $162.

How to save money travelling from Portland, OR to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Portland, OR to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Portland, OR to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Portland, OR to San Diego are also emptier.

All bus stations and stops in Portland, OR and San Diego

In the map below, you can see where to find all bus stations in Portland, OR and San Diego.

Union Bus Station

NW 6th Ave 800

Greyhound Bus Station

NW Station Way 1090

NW Station Way

NW Station Way 1090

Portland Bolt Lloyd Center

NE 13th Ave 1060

Union Train Station

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Portland, OR to San Diego

Want to know which seat classes are available on the buses from Portland, OR to San Diego? Or which bus companies serve the route Portland, OR to San Diego? Below you will find answers to your questions.

FAQs about the Portland, OR to San Diego bus

How much does a Portland, OR San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $153 and takes 28h 35m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Portland, OR to San Diego?

This route is offered by 2 companies with a range of ticket prices between $153 and $420. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Portland, OR to San Diego each day?

Every day, the Portland, OR to San Diego bus route is served by approximately 7 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Portland, OR to San Diego take?

The fastest bus from Portland, OR to San Diego is offered by FlixBus and takes 27h 50m. Bus tickets for this connection cost $234. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Portland, OR to San Diego?

The earliest bus arriving in San Diego from Portland, OR starts at 7:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Portland, OR to San Diego?

The latest bus trip departing from Portland, OR for San Diego starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Portland, OR San Diego route?

When traveling by bus from Portland, OR to San Diego, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Portland, OR and San Diego?

You can check all the direct connections between Portland, OR and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Portland, OR to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Portland, OR San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Portland, OR San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Portland, OR to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Portland, OR to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Portland, OR and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Portland, OR to San Diego?

Prices and availability for 7 trips between Portland, OR and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Portland, OR to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Portland, OR and to San Diego

Here’s an overview of the most popular bus routes to Portland, OR and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!