Bus Portland, OR to Santa Ana, CA - Compare all Companies

Compare all timetables for the bus from Portland, OR to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from Portland, OR to Santa Ana, CA from various bus operators like Greyhound US or FlixBus for the next days.

today

$112

tomorrow

$102

Wednesday

$86

Thursday

Friday

$122

Saturday

$107

Sunday

$108

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 10m	6:50 PM	Portland, OR	Union Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$112	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 6/22/2026 6:50:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/23/2026 10:00:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 27h 10m

Did you know that if you travel from Portland, OR to Santa Ana, CA via Los Angeles, you can save more than $14? You can find the corresponding connections below.
- Greyhound US
  
  31h 25m
  
  0
  
  12:35 AM
  
  Portland, OR
  Greyhound Bus Station
  
  12:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $86
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 6/23/2026 12:35:00 AM to North Hollywood, Los Angeles (USA) arriving at 6/24/2026 12:10:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 23h 35m
- Greyhound US
  
  1h 35m
  
  0
  
  6:25 AM
  
  Los Angeles
  Union Station
  
  8:00 AM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/24/2026 6:25:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/24/2026 8:00:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 35m
Travel time is 4h 15m longer, but you will save $14

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 10m	6:50 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$102	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 6/23/2026 6:50:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/24/2026 10:00:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 27h 10m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 10m	6:50 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$86	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 6/24/2026 6:50:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/25/2026 10:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 27h 10m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 10m	6:50 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$122	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 6/26/2026 6:50:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/27/2026 10:00:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 27h 10m

Did you know that if you travel from Portland, OR to Santa Ana, CA via Los Angeles, you can save more than $24? You can find the corresponding connections below.
- Greyhound US
  
  31h 25m
  
  0
  
  12:35 AM
  
  Portland, OR
  Greyhound Bus Station
  
  12:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $86
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 6/23/2026 12:35:00 AM to North Hollywood, Los Angeles (USA) arriving at 6/24/2026 12:10:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 23h 35m
- Greyhound US
  
  1h 35m
  
  0
  
  6:25 AM
  
  Los Angeles
  Union Station
  
  8:00 AM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $12
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 6/24/2026 6:25:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 6/24/2026 8:00:00 AM. 50 Economy ticket for $12 per person are available. Travel duration is 1h 35m
Travel time is 4h 15m longer, but you will save $24

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	26h 0m	8:00 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$107	A Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 6/27/2026 8:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/28/2026 10:00:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 26h 0m
	Greyhound US	27h 10m	6:50 PM	Portland, OR	Union Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$122	A Bus from Greyhound US goes from Union Bus Station, Portland, OR (USA) at 6/27/2026 6:50:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/28/2026 10:00:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 27h 10m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	27h 10m	6:50 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$108	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 6/28/2026 6:50:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 6/29/2026 10:00:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 27h 10m

Best Price Offer: The price for the cheapest bus from Portland, OR to Santa Ana, CA is $86 on 6/24/2026. Flexible travelers save on ticket prices.

Facts about the bus from Portland, OR to Santa Ana, CA

Compare all providers like Greyhound US and FlixBus that travel 1 times every day by bus from Portland, OR to Santa Ana, CA in one click! Book your bus ticket from Portland, OR to Santa Ana, CA starting from $86!

Cheapest Bus	$86
Fastest Bus	26h 0m
Earliest Bus	6:50 PM
Latest Bus	6:50 PM
Daily Bus Routes	1 Ø
Distance	852.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Portland, OR to Santa Ana, CA

Every day, 1 buses from 2 bus companies leave Portland, OR for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

$112

Tuesday 06/23

$102

Wednesday 06/24

$86

Thursday 06/25

Friday 06/26

$122

Saturday 06/27

$107

Sunday 06/28

$108

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

$108

Saturday 07/11

$108

Sunday 07/12

$99

Monday 07/13

$115

Tuesday 07/14

Wednesday 07/15

$100

Thursday 07/16

$106

Friday 07/17

$106

Saturday 07/18

How to save money travelling from Portland, OR to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Portland, OR to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Portland, OR to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Portland, OR to Santa Ana, CA are also emptier.

All bus stations and stops in Portland, OR and Santa Ana, CA

In the map below, you can see where to find all bus stations in Portland, OR and Santa Ana, CA.

Union Bus Station

NW 6th Ave 800

NW Station Way

NW Station Way 1090

Portland Bolt Lloyd Center

NE 13th Ave 1060

SE 102nd & Washington Bus Stop

Greyhound Bus Station

NW Station Way 1090

Bus Stop

1000 E Santa Ana Blvd 105

Service and Comfort on the bus from Portland, OR to Santa Ana, CA

Want to know which seat classes are available on the buses from Portland, OR to Santa Ana, CA? Or which bus companies serve the route Portland, OR to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the Portland, OR to Santa Ana, CA bus

How much does a Portland, OR Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $86 and takes 27h 10m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from Portland, OR to Santa Ana, CA?

This route is offered by 2 companies with a range of ticket prices between $86 and $126. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from Portland, OR to Santa Ana, CA each day?

Every day, the Portland, OR to Santa Ana, CA bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Portland, OR to Santa Ana, CA take?

The fastest bus from Portland, OR to Santa Ana, CA is offered by FlixBus and takes 26h 0m. Bus tickets for this connection cost $107. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Portland, OR to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from Portland, OR starts at 6:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Portland, OR to Santa Ana, CA?

The latest bus trip departing from Portland, OR for Santa Ana, CA starts at 6:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Portland, OR Santa Ana, CA route?

When traveling by bus from Portland, OR to Santa Ana, CA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Portland, OR and Santa Ana, CA?

You can check all the direct connections between Portland, OR and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Portland, OR to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Portland, OR Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Portland, OR Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Portland, OR to Santa Ana, CA on your planned travel date.

How does CheckMyBus find the best bus deals from Portland, OR to Santa Ana, CA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Portland, OR and Santa Ana, CA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Portland, OR to Santa Ana, CA?

Prices and availability for 1 trips between Portland, OR and Santa Ana, CA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Portland, OR to Santa Ana, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Portland, OR and to Santa Ana, CA

Here’s an overview of the most popular bus routes to Portland, OR and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!