Bus from Portland, OR to Santa Ana, CA from $109

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Portland, OR to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from Portland, OR to Santa Ana, CA from various bus operators like FlixBus or Greyhound US for the next days.

today
from $140
tomorrow
Thursday
Friday
from $114
Saturday
Sunday
from $109
Monday

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    26h 0m
    0
    8:00 PM
    Portland, OR
    Union Bus Station
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $140
  • Greyhound US
    29h 15m
    0
    2:20 AM
    Portland, OR
    Union Bus Station
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $153

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    29h 15m
    0
    2:20 AM
    Portland, OR
    Union Bus Station
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $114
  • FlixBus
    26h 0m
    0
    8:00 PM
    Portland, OR
    Union Bus Station
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $144

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    29h 15m
    0
    2:20 AM
    Portland, OR
    Union Bus Station
    7:35 AM
    Santa Ana, CA
    Bus Stop
    0
    Greyhound US
    Economy
    $109
  • FlixBus
    26h 0m
    0
    8:00 PM
    Portland, OR
    Union Bus Station
    10:00 PM
    Santa Ana, CA
    Bus Stop
    0
    FlixBus
    Economy
    $112

Frequency of bus connections between Portland, OR and Santa Ana, CA

See here how frequent the connections between Portland, OR and Santa Ana, CA are, during different times and days of the week.
Sunday is the busiest day, with more than 2 daily buses from Portland, OR to Santa Ana, CA. Sunday has instead the fewest connections, with only 2 daily coaches between Portland, OR and Santa Ana, CA.
The busiest time of the day is the Evening, with 3 buses from Portland, OR to Santa Ana, CA, while Evening sees the fewest connections between Portland, OR and Santa Ana, CA, with 3 offers.

Facts about the bus from Portland, OR to Santa Ana, CA

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Portland, OR to Santa Ana, CA in one click! Book your bus ticket from Portland, OR to Santa Ana, CA starting from $109!

Cheapest Bus $109
Fastest Bus 26h 0m
Earliest Bus 2:20 AM
Latest Bus 8:00 PM
Daily Bus Routes 2 Ø
Distance 852.9 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Portland, OR to Santa Ana, CA

Every day, 2 buses from 2 bus companies leave Portland, OR for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/08/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/06
Monday 07/07
Tuesday 07/08
$140
Wednesday 07/09
Thursday 07/10
Friday 07/11
$114
Saturday 07/12
Sunday 07/13
$109
Monday 07/14
Tuesday 07/15
Wednesday 07/16
Thursday 07/17
Friday 07/18
Saturday 07/19
Sunday 07/20
Monday 07/21
Tuesday 07/22
Wednesday 07/23
Thursday 07/24
Friday 07/25
Saturday 07/26
Sunday 07/27
Monday 07/28
Tuesday 07/29
Wednesday 07/30
Thursday 07/31
Friday 08/01
Saturday 08/02

The cheapest time to travel from Portland, OR to Santa Ana, CA

See here on which day and which time of the day you can find the cheapest bus ticket from Portland, OR to Santa Ana, CA, for the next 30 days.
With a price starting from $109, Sunday is the cheapest day for a bus from Portland, OR to Santa Ana, CA. Tuesday instead is the most expensive day with prices starting from $140.
Night is the cheapest day time for bus tickets from Portland, OR to Santa Ana, CA, with $109. Evening is the most expensive time of the day with prices starting from $112.

How to save money travelling from Portland, OR to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Portland, OR to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Portland, OR to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Portland, OR to Santa Ana, CA are also emptier.

Beloved bus companies from Portland, OR to Santa Ana, CA

These are the most booked bus companies between Portland, OR to Santa Ana, CA from our users.

FlixBus from Portland, OR to Santa Ana, CA

FlixBus

Here you will find the key facts about the FlixBus bus route Portland, OR to Santa Ana, CA:

Cheapest Price $112
Fastest Bus 26h 0m
Earliest Bus 8:00 PM
Last Bus 8:00 PM
Daily Connections 1 Ø
Found on 7/5/2025

All bus stations and stops in Portland, OR and Santa Ana, CA

In the map below, you can see where to find all bus stations in Portland, OR and Santa Ana, CA.

Service and Comfort on the bus from Portland, OR to Santa Ana, CA

Want to know which seat classes are available on the buses from Portland, OR to Santa Ana, CA? Or which bus companies serve the route Portland, OR to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the Portland, OR to Santa Ana, CA bus

How much does a Portland, OR Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $109 and takes 29h 15m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from Portland, OR to Santa Ana, CA?

This route is offered by 2 companies with a range of ticket prices between $109 and $153. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from Portland, OR to Santa Ana, CA each day?

Every day, the Portland, OR to Santa Ana, CA bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Portland, OR to Santa Ana, CA take?

The fastest bus from Portland, OR to Santa Ana, CA is offered by FlixBus and takes 26h 0m. Bus tickets for this connection cost $140. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Portland, OR to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from Portland, OR starts at 2:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Portland, OR to Santa Ana, CA?

The latest bus trip departing from Portland, OR for Santa Ana, CA starts at 8:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Portland, OR Santa Ana, CA route?

When traveling by bus from Portland, OR to Santa Ana, CA, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Portland, OR and Santa Ana, CA?

You can check all the direct connections between Portland, OR and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Portland, OR to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Portland, OR Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Portland, OR Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Portland, OR to Santa Ana, CA on your planned travel date.

Available seat classes which are offered on the bus route Portland, OR to Santa Ana, CA

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Portland, OR and to Santa Ana, CA

Here’s an overview of the most popular bus routes to Portland, OR and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Seattle, WA to Portland, OR Buses Seattle, WA to Portland, OR
Buses Bend, OR to Portland, OR Buses Bend, OR to Portland, OR
Bus Corvallis, OR to Portland, OR Bus Corvallis, OR to Portland, OR
Bus to Portland, OR from Vancouver, BC Bus to Portland, OR from Vancouver, BC
Bus from Las Vegas to Santa Ana, CA Bus from Las Vegas to Santa Ana, CA
Buses Tijuana, BC - Santa Ana, CA Buses Tijuana, BC - Santa Ana, CA
San Diego to Santa Ana, CA bus San Diego to Santa Ana, CA bus
Bus to Santa Ana, CA from Sacramento Bus to Santa Ana, CA from Sacramento
Popular Airport Shuttles to Portland, OR and to Santa Ana, CA
CheckMyBus › Buses in USA › Bus to Portland, OR › Bus to Santa Ana, CA

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.