Bus Portland, OR to Santa Ana, CA - Compare all Companies

Compare all timetables for the bus from Portland, OR to Santa Ana, CA

Here is a selection of the cheapest bus trips from the schedule from Portland, OR to Santa Ana, CA from various bus operators like Greyhound US or FlixBus for the next days.

today

$121

tomorrow

$139

Sunday

$86

Monday

$127

Tuesday

$114

Wednesday

$120

Thursday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	26h 55m	7:05 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$121	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/16/2026 7:05:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 10/17/2026 10:00:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 26h 55m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	26h 55m	7:05 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$139	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/17/2026 7:05:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 10/18/2026 10:00:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 26h 55m

Did you know that if you travel from Portland, OR to Santa Ana, CA via Los Angeles, you can save more than $39? You can find the corresponding connections below.
- Greyhound US
  
  36h 55m
  
  0
  
  7:05 PM
  
  Portland, OR
  Greyhound Bus Station
  
  9:25 PM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $93
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/18/2026 7:05:00 PM to North Hollywood, Los Angeles (USA) arriving at 10/19/2026 9:25:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 26h 20m
- Greyhound US
  
  1h 35m
  
  0
  
  6:25 AM
  
  Los Angeles
  Union Station
  
  8:00 AM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 10/20/2026 6:25:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 10/20/2026 8:00:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 35m
Travel time is 10h 0m longer, but you will save $39

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	26h 0m	8:00 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$86	A Bus from FlixBus goes from Greyhound Bus Station, Portland, OR (USA) at 10/18/2026 8:00:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 10/19/2026 10:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 26h 0m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	26h 55m	7:05 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$127	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/19/2026 7:05:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 10/20/2026 10:00:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 26h 55m

Did you know that if you travel from Portland, OR to Santa Ana, CA via Los Angeles, you can save more than $30? You can find the corresponding connections below.
- Greyhound US
  
  31h 25m
  
  0
  
  12:35 AM
  
  Portland, OR
  Greyhound Bus Station
  
  12:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $90
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/20/2026 12:35:00 AM to North Hollywood, Los Angeles (USA) arriving at 10/21/2026 12:10:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 23h 35m
- Greyhound US
  
  1h 35m
  
  0
  
  6:25 AM
  
  Los Angeles
  Union Station
  
  8:00 AM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 10/21/2026 6:25:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 10/21/2026 8:00:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 35m
Travel time is 4h 30m longer, but you will save $30

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	26h 55m	7:05 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$114	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/20/2026 7:05:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 10/21/2026 10:00:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 26h 55m

Did you know that if you travel from Portland, OR to Santa Ana, CA via Los Angeles, you can save more than $17? You can find the corresponding connections below.
- Greyhound US
  
  31h 25m
  
  0
  
  12:35 AM
  
  Portland, OR
  Greyhound Bus Station
  
  12:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $90
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/20/2026 12:35:00 AM to North Hollywood, Los Angeles (USA) arriving at 10/21/2026 12:10:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 23h 35m
- Greyhound US
  
  1h 35m
  
  0
  
  6:25 AM
  
  Los Angeles
  Union Station
  
  8:00 AM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 10/21/2026 6:25:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 10/21/2026 8:00:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 35m
Travel time is 4h 30m longer, but you will save $17

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	26h 55m	7:05 PM	Portland, OR	Greyhound Bus Station	10:00 PM	Santa Ana, CA	Bus Stop		Economy	$120	A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/21/2026 7:05:00 PM to Bus Stop, Santa Ana, CA (USA) arriving at 10/22/2026 10:00:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 26h 55m

Did you know that if you travel from Portland, OR to Santa Ana, CA via Los Angeles, you can save more than $23? You can find the corresponding connections below.
- Greyhound US
  
  31h 25m
  
  0
  
  12:35 AM
  
  Portland, OR
  Greyhound Bus Station
  
  12:10 AM
  
  Los Angeles
  North Hollywood
  
  0
  
  Economy
  
  $90
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Portland, OR (USA) at 10/20/2026 12:35:00 AM to North Hollywood, Los Angeles (USA) arriving at 10/21/2026 12:10:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 23h 35m
- Greyhound US
  
  1h 35m
  
  0
  
  6:25 AM
  
  Los Angeles
  Union Station
  
  8:00 AM
  
  Santa Ana, CA
  Bus Stop
  
  0
  
  Economy
  
  $6
  
  A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 10/21/2026 6:25:00 AM to Bus Stop, Santa Ana, CA (USA) arriving at 10/21/2026 8:00:00 AM. 50 Economy ticket for $6 per person are available. Travel duration is 1h 35m
Travel time is 4h 30m longer, but you will save $23

Best Price Offer: The price for the cheapest bus from Portland, OR to Santa Ana, CA is $86 on 10/18/2026. Flexible travelers save on ticket prices.

Facts about the bus from Portland, OR to Santa Ana, CA

Compare all providers like Greyhound US and FlixBus that travel 1 times every day by bus from Portland, OR to Santa Ana, CA in one click! Book your bus ticket from Portland, OR to Santa Ana, CA starting from $86!

Cheapest Bus	$86
Fastest Bus	26h 0m
Earliest Bus	7:05 PM
Latest Bus	7:05 PM
Daily Bus Routes	1 Ø
Distance	852.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Portland, OR to Santa Ana, CA

Every day, 1 buses from 2 bus companies leave Portland, OR for Santa Ana, CA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/16/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/11

Monday 10/12

Tuesday 10/13

Wednesday 10/14

Thursday 10/15

Friday 10/16

$121

Saturday 10/17

$139

Sunday 10/18

$86

Monday 10/19

$127

Tuesday 10/20

$118

Wednesday 10/21

$120

Thursday 10/22

Friday 10/23

$150

Saturday 10/24

$156

Sunday 10/25

Monday 10/26

Tuesday 10/27

$137

Wednesday 10/28

Thursday 10/29

$157

Friday 10/30

Saturday 10/31

$100

Sunday 11/01

Monday 11/02

$140

Tuesday 11/03

$117

Wednesday 11/04

$123

Thursday 11/05

$133

Friday 11/06

$137

Saturday 11/07

How to save money travelling from Portland, OR to Santa Ana, CA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Portland, OR to Santa Ana, CA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Portland, OR to Santa Ana, CA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Portland, OR to Santa Ana, CA are also emptier.

Beloved bus companies from Portland, OR to Santa Ana, CA

These are the most booked bus companies between Portland, OR to Santa Ana, CA from our users.

Greyhound US from Portland, OR to Santa Ana, CA

Here you will find the key facts about the Greyhound US bus route Portland, OR to Santa Ana, CA:

Cheapest Price	$114
Fastest Bus	26h 55m
Earliest Bus	7:05 PM
Last Bus	7:05 PM
Daily Connections	1 Ø
Found on	9/20/2026

All bus stations and stops in Portland, OR and Santa Ana, CA

In the map below, you can see where to find all bus stations in Portland, OR and Santa Ana, CA.

Union Bus Station

NW 6th Ave 800

NW Station Way

NW Station Way 1090

Greyhound Bus Station

NW Station Way 1090

Portland Bolt Lloyd Center

NE 13th Ave 1060

SE 102nd & Washington Bus Stop

Bus Stop

1000 E Santa Ana Blvd 105

Train Station

W 1st St 101-155

Service and Comfort on the bus from Portland, OR to Santa Ana, CA

Want to know which seat classes are available on the buses from Portland, OR to Santa Ana, CA? Or which bus companies serve the route Portland, OR to Santa Ana, CA? Below you will find answers to your questions.

FAQs about the Portland, OR to Santa Ana, CA bus

How much does a Portland, OR Santa Ana, CA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $86 and takes 26h 0m to reach Santa Ana, CA. Compare offers to save money!

How much could I save by comparing buses from Portland, OR to Santa Ana, CA?

This route is offered by 2 companies with a range of ticket prices between $86 and $139. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Santa Ana, CA.

On average, how many connections are available from Portland, OR to Santa Ana, CA each day?

Every day, the Portland, OR to Santa Ana, CA bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Portland, OR to Santa Ana, CA take?

The fastest bus from Portland, OR to Santa Ana, CA is offered by FlixBus and takes 26h 0m. Bus tickets for this connection cost $86. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Portland, OR to Santa Ana, CA?

The earliest bus arriving in Santa Ana, CA from Portland, OR starts at 7:05 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Portland, OR to Santa Ana, CA?

The latest bus trip departing from Portland, OR for Santa Ana, CA starts at 7:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Portland, OR Santa Ana, CA route?

When traveling by bus from Portland, OR to Santa Ana, CA, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Portland, OR and Santa Ana, CA?

You can check all the direct connections between Portland, OR and Santa Ana, CA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Portland, OR to Santa Ana, CA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Portland, OR Santa Ana, CA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Portland, OR Santa Ana, CA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Portland, OR to Santa Ana, CA on your planned travel date.

How does CheckMyBus find the best bus deals from Portland, OR to Santa Ana, CA?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Portland, OR and Santa Ana, CA. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Portland, OR to Santa Ana, CA?

Prices and availability for 1 trips between Portland, OR and Santa Ana, CA change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Portland, OR to Santa Ana, CA

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Portland, OR and to Santa Ana, CA

Here’s an overview of the most popular bus routes to Portland, OR and to Santa Ana, CA. Simply click on the connection of your choice, and you will find all the details about your bus route!