Bus Boston, MA to San Diego - Compare all Companies

Compare all timetables for the bus from Boston, MA to San Diego

Here is a selection of the cheapest bus trips from the schedule from Boston, MA to San Diego from various bus operators like Greyhound US or FlixBus for the next days.

today

$247

tomorrow

$263

Sunday

Monday

$236

Tuesday

Wednesday

$219

Thursday

$247

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	80h 40m	8:30 AM	Boston, MA	South Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$247	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/5/2025 8:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 2:10:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 80h 40m
Greyhound US	80h 10m	8:30 AM	Boston, MA	South Station	1:40 PM	San Diego	La Jolla Village	Economy	$247	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/5/2025 8:30:00 AM to La Jolla Village, San Diego (USA) arriving at 12/8/2025 1:40:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 80h 10m
FlixBus	89h 50m	8:55 PM	Boston, MA	Allston	11:45 AM	San Diego	Old Town Transit Center	Economy	$248	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/5/2025 8:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/9/2025 11:45:00 AM. 50 Economy ticket for $248 per person are available. Travel duration is 89h 50m
Greyhound US	73h 10m	7:35 PM	Boston, MA	South Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$254	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/5/2025 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 5:45:00 PM. 50 Economy ticket for $254 per person are available. Travel duration is 73h 10m
FlixBus	87h 40m	1:30 AM	Boston, MA	Allston	2:10 PM	San Diego	Old Town Transit Center	Economy	$277	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/5/2025 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/8/2025 2:10:00 PM. 50 Economy ticket for $277 per person are available. Travel duration is 87h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	85h 15m	1:30 AM	Boston, MA	Allston	11:45 AM	San Diego	Old Town Transit Center	Economy	$263	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/6/2025 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/9/2025 11:45:00 AM. 50 Economy ticket for $263 per person are available. Travel duration is 85h 15m
FlixBus	89h 50m	8:55 PM	Boston, MA	Allston	11:45 AM	San Diego	Old Town Transit Center	Economy	$289	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/6/2025 8:55:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/10/2025 11:45:00 AM. 50 Economy ticket for $289 per person are available. Travel duration is 89h 50m
Greyhound US	73h 10m	7:35 PM	Boston, MA	South Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$335	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/6/2025 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/9/2025 5:45:00 PM. 50 Economy ticket for $335 per person are available. Travel duration is 73h 10m
Greyhound US	73h 0m	7:35 PM	Boston, MA	South Station	5:35 PM	San Diego	La Jolla Village	Economy	$339	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/6/2025 7:35:00 PM to La Jolla Village, San Diego (USA) arriving at 12/9/2025 5:35:00 PM. 50 Economy ticket for $339 per person are available. Travel duration is 73h 0m
Greyhound US	73h 35m	7:35 PM	Boston, MA	South Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$341	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/6/2025 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/9/2025 6:10:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 73h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	85h 50m	1:30 AM	Boston, MA	Allston	12:20 PM	San Diego	San Ysidro Transit Center	Economy	$236	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/8/2025 1:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/11/2025 12:20:00 PM. 50 Economy ticket for $236 per person are available. Travel duration is 85h 50m
Greyhound US	74h 10m	7:35 PM	Boston, MA	South Station	6:45 PM	San Diego	San Ysidro Transit Center	Economy	$246	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/8/2025 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/11/2025 6:45:00 PM. 50 Economy ticket for $246 per person are available. Travel duration is 74h 10m
FlixBus	88h 40m	8:55 PM	Boston, MA	Allston	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$248	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/8/2025 8:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/12/2025 10:35:00 AM. 50 Economy ticket for $248 per person are available. Travel duration is 88h 40m
Greyhound US	81h 0m	8:10 AM	Boston, MA	South Station	2:10 PM	San Diego	Old Town Transit Center	Economy	$285	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/8/2025 8:10:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/11/2025 2:10:00 PM. 50 Economy ticket for $285 per person are available. Travel duration is 81h 0m
Greyhound US	80h 30m	8:10 AM	Boston, MA	South Station	1:40 PM	San Diego	La Jolla Village	Economy	$285	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/8/2025 8:10:00 AM to La Jolla Village, San Diego (USA) arriving at 12/11/2025 1:40:00 PM. 50 Economy ticket for $285 per person are available. Travel duration is 80h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	73h 45m	7:35 PM	Boston, MA	South Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$219	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/10/2025 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/13/2025 6:20:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 73h 45m
FlixBus	88h 40m	8:55 PM	Boston, MA	Allston	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$248	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/10/2025 8:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/14/2025 10:35:00 AM. 50 Economy ticket for $248 per person are available. Travel duration is 88h 40m
Greyhound US	73h 35m	7:35 PM	Boston, MA	South Station	6:10 PM	San Diego	Old Town Transit Center	Economy	$376	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/10/2025 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 6:10:00 PM. 50 Economy ticket for $376 per person are available. Travel duration is 73h 35m
Greyhound US	73h 10m	7:35 PM	Boston, MA	South Station	5:45 PM	San Diego	Old Town Transit Center	Economy	$376	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/10/2025 7:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 5:45:00 PM. 50 Economy ticket for $376 per person are available. Travel duration is 73h 10m
FlixBus	87h 40m	1:30 AM	Boston, MA	Allston	2:10 PM	San Diego	Old Town Transit Center	Economy	$380	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/10/2025 1:30:00 AM to Old Town Transit Center, San Diego (USA) arriving at 12/13/2025 2:10:00 PM. 50 Economy ticket for $380 per person are available. Travel duration is 87h 40m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	88h 40m	8:55 PM	Boston, MA	Allston	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$247	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/11/2025 8:55:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/15/2025 10:35:00 AM. 50 Economy ticket for $247 per person are available. Travel duration is 88h 40m
FlixBus	84h 5m	1:30 AM	Boston, MA	Allston	10:35 AM	San Diego	San Ysidro Transit Center	Economy	$254	A Bus from FlixBus goes from Allston, Boston, MA (USA) at 12/11/2025 1:30:00 AM to San Ysidro Transit Center, San Diego (USA) arriving at 12/14/2025 10:35:00 AM. 50 Economy ticket for $254 per person are available. Travel duration is 84h 5m
Greyhound US	73h 45m	7:35 PM	Boston, MA	South Station	6:20 PM	San Diego	San Ysidro Transit Center	Economy	$264	A Bus from Greyhound US goes from South Station, Boston, MA (USA) at 12/11/2025 7:35:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 12/14/2025 6:20:00 PM. 50 Economy ticket for $264 per person are available. Travel duration is 73h 45m

Best Price Offer: The price for the cheapest bus from Boston, MA to San Diego is $219 on 12/10/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Boston, MA and San Diego

See here how frequent the connections between Boston, MA and San Diego are, during different times and days of the week.

Monday is the busiest day, with more than 15 daily buses from Boston, MA to San Diego. Thursday has instead the fewest connections, with only 3 daily coaches between Boston, MA and San Diego.

The busiest time of the day is the Evening, with 31 buses from Boston, MA to San Diego, while Morning sees the fewest connections between Boston, MA and San Diego, with 6 offers.

Facts about the bus from Boston, MA to San Diego

Compare all providers like Greyhound US and FlixBus that travel 9 times every day by bus from Boston, MA to San Diego in one click! Book your bus ticket from Boston, MA to San Diego starting from $219!

Cheapest Bus	$219
Fastest Bus	70h 0m
Earliest Bus	1:30 AM
Latest Bus	8:55 PM
Daily Bus Routes	9 Ø
Distance	2,579.0 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Boston, MA to San Diego

Every day, 9 buses from 2 bus companies leave Boston, MA for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$247

Saturday 12/06

$263

Sunday 12/07

Monday 12/08

$236

Tuesday 12/09

Wednesday 12/10

$376

Thursday 12/11

$247

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Boston, MA to San Diego

See here on which day and which time of the day you can find the cheapest bus ticket from Boston, MA to San Diego, for the next 30 days.

With a price starting from $219, Wednesday is the cheapest day for a bus from Boston, MA to San Diego. Saturday instead is the most expensive day with prices starting from $263.

Evening is the cheapest day time for bus tickets from Boston, MA to San Diego, with $219. Morning is the most expensive time of the day with prices starting from $247.

How to save money travelling from Boston, MA to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Boston, MA to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Boston, MA to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Boston, MA to San Diego are also emptier.

Beloved bus companies from Boston, MA to San Diego

These are the most booked bus companies between Boston, MA to San Diego from our users.

Greyhound US from Boston, MA to San Diego

Here you will find the key facts about the Greyhound US bus route Boston, MA to San Diego:

Cheapest Price	$219
Fastest Bus	70h 0m
Earliest Bus	1:30 AM
Last Bus	7:35 PM
Daily Connections	5 Ø
Found on	12/3/2025

All bus stations and stops in Boston, MA and San Diego

In the map below, you can see where to find all bus stations in Boston, MA and San Diego.

South Station

Atlantic Ave 700

Prudential Center T Transit Station

Huntington Ave 220

Sheraton Hotel

Dalton St 39

South Station Gate 12

Atlantic Ave 700

Copley Square

Boylston Street

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

La Jolla Village

Hyatt Regency

Service and Comfort on the bus from Boston, MA to San Diego

Want to know which seat classes are available on the buses from Boston, MA to San Diego? Or which bus companies serve the route Boston, MA to San Diego? Below you will find answers to your questions.

FAQs about the Boston, MA to San Diego bus

How much does a Boston, MA San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $219 and takes 70h 45m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Boston, MA to San Diego?

This route is offered by 2 companies with a range of ticket prices between $219 and $407. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Boston, MA to San Diego each day?

Every day, the Boston, MA to San Diego bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Boston, MA to San Diego take?

The fastest bus from Boston, MA to San Diego is offered by Greyhound US and takes 70h 0m. Bus tickets for this connection cost $256. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Boston, MA to San Diego?

The earliest bus arriving in San Diego from Boston, MA starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Boston, MA to San Diego?

The latest bus trip departing from Boston, MA for San Diego starts at 8:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Boston, MA San Diego route?

When traveling by bus from Boston, MA to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Boston, MA and San Diego?

You can check all the direct connections between Boston, MA and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Boston, MA to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Boston, MA San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Boston, MA San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Boston, MA to San Diego on your planned travel date.

Available seat classes which are offered on the bus route Boston, MA to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Boston, MA and to San Diego

Here’s an overview of the most popular bus routes to Boston, MA and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!