Bus Rochester, NY to San Diego - Compare all Companies

Compare all timetables for the bus from Rochester, NY to San Diego

Here is a selection of the cheapest bus trips from the schedule from Rochester, NY to San Diego from various bus operators like Greyhound US or FlixBus for the next days.

today

$219

tomorrow

$223

Saturday

Sunday

Monday

Tuesday

Wednesday

$222

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	70h 55m	9:15 PM	Rochester, NY	Greyhound	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$219	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/3/2026 9:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 9/6/2026 5:10:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 70h 55m
Greyhound US	70h 10m	9:15 PM	Rochester, NY	Greyhound	4:25 PM	San Diego	Old Town Transit Center	Economy	$219	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/3/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/6/2026 4:25:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 70h 10m
Greyhound US	69h 40m	9:15 PM	Rochester, NY	Greyhound	3:55 PM	San Diego	La Jolla Village	Economy	$219	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/3/2026 9:15:00 PM to La Jolla Village, San Diego (USA) arriving at 9/6/2026 3:55:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 69h 40m
Greyhound US	76h 0m	9:15 PM	Rochester, NY	Greyhound	10:15 PM	San Diego	Seaport Village	Economy	$239	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/3/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 9/6/2026 10:15:00 PM. 50 Economy ticket for $239 per person are available. Travel duration is 76h 0m
Greyhound US	71h 30m	9:15 PM	Rochester, NY	Greyhound	5:45 PM	San Diego	Old Town Transit Center	Economy	$239	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/3/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/6/2026 5:45:00 PM. 50 Economy ticket for $239 per person are available. Travel duration is 71h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	69h 40m	9:15 PM	Rochester, NY	Greyhound	3:55 PM	San Diego	La Jolla Village	Economy	$223	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/4/2026 9:15:00 PM to La Jolla Village, San Diego (USA) arriving at 9/7/2026 3:55:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 69h 40m
Greyhound US	70h 55m	9:15 PM	Rochester, NY	Greyhound	5:10 PM	San Diego	San Ysidro Transit Center	Economy	$223	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/4/2026 9:15:00 PM to San Ysidro Transit Center, San Diego (USA) arriving at 9/7/2026 5:10:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 70h 55m
Greyhound US	70h 10m	9:15 PM	Rochester, NY	Greyhound	4:25 PM	San Diego	Old Town Transit Center	Economy	$225	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/4/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 4:25:00 PM. 50 Economy ticket for $225 per person are available. Travel duration is 70h 10m
Greyhound US	76h 0m	9:15 PM	Rochester, NY	Greyhound	10:15 PM	San Diego	Seaport Village	Economy	$246	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/4/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 9/7/2026 10:15:00 PM. 50 Economy ticket for $246 per person are available. Travel duration is 76h 0m
Greyhound US	71h 30m	9:15 PM	Rochester, NY	Greyhound	5:45 PM	San Diego	Old Town Transit Center	Economy	$252	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/4/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/7/2026 5:45:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 71h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	69h 40m	9:15 PM	Rochester, NY	Greyhound	3:55 PM	San Diego	La Jolla Village	Economy	$222	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/9/2026 9:15:00 PM to La Jolla Village, San Diego (USA) arriving at 9/12/2026 3:55:00 PM. 50 Economy ticket for $222 per person are available. Travel duration is 69h 40m
Greyhound US	70h 10m	9:15 PM	Rochester, NY	Greyhound	4:25 PM	San Diego	Old Town Transit Center	Economy	$224	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/9/2026 9:15:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/12/2026 4:25:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 70h 10m
FlixBus	85h 50m	11:35 PM	Rochester, NY	Greyhound	10:25 AM	San Diego	Seaport Village	Economy	$236	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 9/9/2026 11:35:00 PM to Seaport Village, San Diego (USA) arriving at 9/13/2026 10:25:00 AM. 50 Economy ticket for $236 per person are available. Travel duration is 85h 50m
FlixBus	85h 30m	11:35 PM	Rochester, NY	Greyhound	10:05 AM	San Diego	Old Town Transit Center	Economy	$236	A Bus from FlixBus goes from Greyhound, Rochester, NY (USA) at 9/9/2026 11:35:00 PM to Old Town Transit Center, San Diego (USA) arriving at 9/13/2026 10:05:00 AM. 50 Economy ticket for $236 per person are available. Travel duration is 85h 30m
Greyhound US	76h 0m	9:15 PM	Rochester, NY	Greyhound	10:15 PM	San Diego	Seaport Village	Economy	$267	A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/9/2026 9:15:00 PM to Seaport Village, San Diego (USA) arriving at 9/12/2026 10:15:00 PM. 50 Economy ticket for $267 per person are available. Travel duration is 76h 0m

Did you know that if you travel from Rochester, NY to San Diego via Milwaukee, you can save more than $24? You can find the corresponding connections below.
- Greyhound US
  
  94h 10m
  
  0
  
  9:15 PM
  
  Rochester, NY
  Greyhound
  
  5:00 PM
  
  Milwaukee
  Central Bus Station
  
  0
  
  Economy
  
  $85
  
  A Bus from Greyhound US goes from Greyhound, Rochester, NY (USA) at 9/7/2026 9:15:00 PM to Central Bus Station, Milwaukee (USA) arriving at 9/8/2026 5:00:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 20h 45m
- FlixBus
  
  57h 25m
  
  0
  
  9:00 AM
  
  Milwaukee
  Central Bus Station
  
  4:25 PM
  
  San Diego
  Old Town Transit Center
  
  0
  
  Economy
  
  $113
  
  A Bus from FlixBus goes from Central Bus Station, Milwaukee (USA) at 9/9/2026 9:00:00 AM to Old Town Transit Center, San Diego (USA) arriving at 9/11/2026 4:25:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 57h 25m
Travel time is 27h 30m longer, but you will save $24

Best Price Offer: The price for the cheapest bus from Rochester, NY to San Diego is $219 on 9/3/2026. Flexible travelers save on ticket prices.

Facts about the bus from Rochester, NY to San Diego

Compare all providers like Greyhound US and FlixBus that travel 5 times every day by bus from Rochester, NY to San Diego in one click! Book your bus ticket from Rochester, NY to San Diego starting from $219!

Cheapest Bus	$219
Fastest Bus	66h 40m
Earliest Bus	9:15 PM
Latest Bus	11:35 PM
Daily Bus Routes	5 Ø
Distance	2,249.4 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Rochester, NY to San Diego

Every day, 5 buses from 2 bus companies leave Rochester, NY for San Diego: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/03/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 08/30

Monday 08/31

Tuesday 09/01

Wednesday 09/02

Thursday 09/03

$219

Friday 09/04

$223

Saturday 09/05

Sunday 09/06

Monday 09/07

Tuesday 09/08

Wednesday 09/09

$222

Thursday 09/10

$221

Friday 09/11

$219

Saturday 09/12

$219

Sunday 09/13

Monday 09/14

$222

Tuesday 09/15

$222

Wednesday 09/16

$222

Thursday 09/17

Friday 09/18

$222

Saturday 09/19

$241

Sunday 09/20

$235

Monday 09/21

Tuesday 09/22

$237

Wednesday 09/23

$240

Thursday 09/24

Friday 09/25

$231

Saturday 09/26

How to save money travelling from Rochester, NY to San Diego

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rochester, NY to San Diego in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rochester, NY to San Diego, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rochester, NY to San Diego are also emptier.

Beloved bus companies from Rochester, NY to San Diego

These are the most booked bus companies between Rochester, NY to San Diego from our users.

Greyhound US from Rochester, NY to San Diego

Here you will find the key facts about the Greyhound US bus route Rochester, NY to San Diego:

Cheapest Price	$219
Fastest Bus	66h 40m
Earliest Bus	9:15 PM
Last Bus	9:15 PM
Daily Connections	4 Ø
Found on	8/9/2026

All bus stations and stops in Rochester, NY and San Diego

In the map below, you can see where to find all bus stations in Rochester, NY and San Diego.

Greyhound

Cumberland St 186

Rush Rhees Library

Library Rd 755

Trailways-LATS

Airport & Terminal Lower Leve

Raj Mahal Indian Restaurant

Jefferson Road 368

Old Town Transit Center

Congress Street 2727

San Ysidro Transit Center

E San Ysidro Blvd 723

Santa Fe Depot

Kettner Blvd 1050

Seaport Village

W Harbor Dr 789

Downtown

Service and Comfort on the bus from Rochester, NY to San Diego

Want to know which seat classes are available on the buses from Rochester, NY to San Diego? Or which bus companies serve the route Rochester, NY to San Diego? Below you will find answers to your questions.

FAQs about the Rochester, NY to San Diego bus

How much does a Rochester, NY San Diego bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $219 and takes 67h 55m to reach San Diego. Compare offers to save money!

How much could I save by comparing buses from Rochester, NY to San Diego?

This route is offered by 2 companies with a range of ticket prices between $219 and $269. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Diego.

On average, how many connections are available from Rochester, NY to San Diego each day?

Every day, the Rochester, NY to San Diego bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rochester, NY to San Diego take?

The fastest bus from Rochester, NY to San Diego is offered by Greyhound US and takes 66h 40m. Bus tickets for this connection cost $219. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rochester, NY to San Diego?

The earliest bus arriving in San Diego from Rochester, NY starts at 9:15 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rochester, NY to San Diego?

The latest bus trip departing from Rochester, NY for San Diego starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rochester, NY San Diego route?

When traveling by bus from Rochester, NY to San Diego, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rochester, NY and San Diego?

You can check all the direct connections between Rochester, NY and San Diego by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Rochester, NY to San Diego bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rochester, NY San Diego bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rochester, NY San Diego bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rochester, NY to San Diego on your planned travel date.

How does CheckMyBus find the best bus deals from Rochester, NY to San Diego?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Rochester, NY and San Diego. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rochester, NY to San Diego?

Prices and availability for 5 trips between Rochester, NY and San Diego change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rochester, NY to San Diego

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rochester, NY and to San Diego

Here’s an overview of the most popular bus routes to Rochester, NY and to San Diego. Simply click on the connection of your choice, and you will find all the details about your bus route!