Bus from Syracuse, NY to Indianapolis from $89

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Syracuse, NY to Indianapolis

Here is a selection of the cheapest bus trips from the schedule from Syracuse, NY to Indianapolis from various bus operators like Greyhound US for the next days.

today
$101
tomorrow
$110
Saturday
Sunday
$103
Monday
Tuesday
$96
Wednesday
$102

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 21h 10m 7:35 PM Syracuse, NY Regional Transit Center 4:45 PM Indianapolis Central Bus Station  Economy $101
Greyhound US 17h 40m 7:35 PM Syracuse, NY Regional Transit Center 1:15 PM Indianapolis Downtown Transit Center  Economy $102
Greyhound US 22h 30m 4:30 AM Syracuse, NY Regional Transit Center 3:00 AM Indianapolis Downtown Transit Center  Economy $110
Greyhound US 14h 50m 4:30 AM Syracuse, NY Regional Transit Center 7:20 PM Indianapolis Central Bus Station  Economy $110

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 30m 4:30 AM Syracuse, NY Regional Transit Center 3:00 AM Indianapolis Washington / Delaware  Economy $110
Greyhound US 17h 40m 7:35 PM Syracuse, NY Regional Transit Center 1:15 PM Indianapolis Washington / Delaware  Economy $110
Greyhound US 14h 50m 4:30 AM Syracuse, NY Regional Transit Center 7:20 PM Indianapolis Central Bus Station  Economy $111
Greyhound US 21h 10m 7:35 PM Syracuse, NY Regional Transit Center 4:45 PM Indianapolis Central Bus Station  Economy $111
  • Did you know that if you travel from Syracuse, NY to Indianapolis via Cleveland, you can save more than $13? You can find the corresponding connections below.
    • Greyhound US
      14h 50m
      0
      4:30 AM
      Syracuse, NY
      Regional Transit Center
      11:45 AM
      Cleveland
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $47
      • Waiting Time 0h 35m
    • Greyhound US
      7h 0m
      0
      12:20 PM
      Cleveland
      Greyhound Bus Station
      7:20 PM
      Indianapolis
      Central Bus Station
      0
      Greyhound US
      Economy
      $50
    Travel time is the same as the direct connection, but you will save $13

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 50m 4:30 AM Syracuse, NY Regional Transit Center 7:20 PM Indianapolis Central Bus Station  Economy $103
Greyhound US 22h 30m 4:30 AM Syracuse, NY Regional Transit Center 3:00 AM Indianapolis Downtown Transit Center  Economy $104
Greyhound US 17h 40m 7:35 PM Syracuse, NY Regional Transit Center 1:15 PM Indianapolis Downtown Transit Center  Economy $104
Greyhound US 21h 10m 7:35 PM Syracuse, NY Regional Transit Center 4:45 PM Indianapolis Central Bus Station  Economy $104

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 21h 10m 7:35 PM Syracuse, NY Regional Transit Center 4:45 PM Indianapolis Central Bus Station  Economy $96
Greyhound US 14h 50m 4:30 AM Syracuse, NY Regional Transit Center 7:20 PM Indianapolis Central Bus Station  Economy $97
Greyhound US 17h 40m 7:35 PM Syracuse, NY Regional Transit Center 1:15 PM Indianapolis Washington / Delaware  Economy $100

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 30m 4:30 AM Syracuse, NY Regional Transit Center 3:00 AM Indianapolis Washington / Delaware  Economy $102
Greyhound US 17h 40m 7:35 PM Syracuse, NY Regional Transit Center 1:15 PM Indianapolis Washington / Delaware  Economy $103
Greyhound US 14h 50m 4:30 AM Syracuse, NY Regional Transit Center 7:20 PM Indianapolis Central Bus Station  Economy $103
Greyhound US 21h 10m 7:35 PM Syracuse, NY Regional Transit Center 4:45 PM Indianapolis Central Bus Station  Economy $105

Best Price Offer: The price for the cheapest bus from Syracuse, NY to Indianapolis is $89 on 8/25/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Syracuse, NY and Indianapolis

See here how frequent the connections between Syracuse, NY and Indianapolis are, during different times and days of the week.
Sunday is the busiest day, with more than 8 daily buses from Syracuse, NY to Indianapolis. Wednesday has instead the fewest connections, with only 4 daily coaches between Syracuse, NY and Indianapolis.
The busiest time of the day is the Evening, with 15 buses from Syracuse, NY to Indianapolis, while Night sees the fewest connections between Syracuse, NY and Indianapolis, with 14 offers.

Facts about the bus from Syracuse, NY to Indianapolis

Compare all providers like Greyhound US that travel 5 times every day by bus from Syracuse, NY to Indianapolis in one click! Book your bus ticket from Syracuse, NY to Indianapolis starting from $89!

Cheapest Bus $89
Fastest Bus 14h 50m
Earliest Bus 4:30 AM
Latest Bus 7:35 PM
Daily Bus Routes 5 Ø
Distance 565.9 miles
Bus Companies Greyhound US

Cheapest bus connections from Syracuse, NY to Indianapolis

Every day, 5 buses from 1 bus companies leave Syracuse, NY for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/02
Monday 08/03
Tuesday 08/04
Wednesday 08/05
Thursday 08/06
$105
Friday 08/07
$110
Saturday 08/08
Sunday 08/09
$108
Monday 08/10
Tuesday 08/11
$96
Wednesday 08/12
$102
Thursday 08/13
Friday 08/14
$100
Saturday 08/15
$104
Sunday 08/16
$106
Monday 08/17
$108
Tuesday 08/18
$100
Wednesday 08/19
Thursday 08/20
$110
Friday 08/21
$109
Saturday 08/22
$106
Sunday 08/23
Monday 08/24
$110
Tuesday 08/25
$89
Wednesday 08/26
$91
Thursday 08/27
Friday 08/28
Saturday 08/29

The cheapest time to travel from Syracuse, NY to Indianapolis

See here on which day and which time of the day you can find the cheapest bus ticket from Syracuse, NY to Indianapolis, for the next 30 days.
With a price starting from $89, Tuesday is the cheapest day for a bus from Syracuse, NY to Indianapolis. Thursday instead is the most expensive day with prices starting from $101.
Night is the cheapest day time for bus tickets from Syracuse, NY to Indianapolis, with $89. Evening is the most expensive time of the day with prices starting from $96.

How to save money travelling from Syracuse, NY to Indianapolis

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Syracuse, NY to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Syracuse, NY to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Syracuse, NY to Indianapolis are also emptier.

Beloved bus companies from Syracuse, NY to Indianapolis

These are the most booked bus companies between Syracuse, NY to Indianapolis from our users.

Greyhound US from Syracuse, NY to Indianapolis

Greyhound US

Here you will find the key facts about the Greyhound US bus route Syracuse, NY to Indianapolis:

Cheapest Price $96
Fastest Bus 14h 50m
Earliest Bus 4:30 AM
Last Bus 7:35 PM
Daily Connections 5 Ø
Found on 7/12/2026

All bus stations and stops in Syracuse, NY and Indianapolis

In the map below, you can see where to find all bus stations in Syracuse, NY and Indianapolis.

Service and Comfort on the bus from Syracuse, NY to Indianapolis

Want to know which seat classes are available on the buses from Syracuse, NY to Indianapolis? Or which bus companies serve the route Syracuse, NY to Indianapolis? Below you will find answers to your questions.

FAQs about the Syracuse, NY to Indianapolis bus

How much does a Syracuse, NY Indianapolis bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $89 and takes 21h 10m to reach Indianapolis. Compare offers to save money!

How much could I save by comparing buses from Syracuse, NY to Indianapolis?

This route is offered by 1 companies with a range of ticket prices between $89 and $114. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.

On average, how many connections are available from Syracuse, NY to Indianapolis each day?

Every day, the Syracuse, NY to Indianapolis bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Syracuse, NY to Indianapolis take?

The fastest bus from Syracuse, NY to Indianapolis is offered by Greyhound US and takes 14h 50m. Bus tickets for this connection cost $110. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Syracuse, NY to Indianapolis?

The earliest bus arriving in Indianapolis from Syracuse, NY starts at 4:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Syracuse, NY to Indianapolis?

The latest bus trip departing from Syracuse, NY for Indianapolis starts at 7:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Syracuse, NY Indianapolis route?

When traveling by bus from Syracuse, NY to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Syracuse, NY and Indianapolis?

You can check all the direct connections between Syracuse, NY and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Syracuse, NY to Indianapolis bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Syracuse, NY Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Syracuse, NY Indianapolis bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Syracuse, NY to Indianapolis on your planned travel date.

How does CheckMyBus find the best bus deals from Syracuse, NY to Indianapolis?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Syracuse, NY and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Syracuse, NY to Indianapolis?

Prices and availability for 5 trips between Syracuse, NY and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Syracuse, NY to Indianapolis

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Syracuse, NY and to Indianapolis

Here’s an overview of the most popular bus routes to Syracuse, NY and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Wilmington, DE - Syracuse, NY Bus Wilmington, DE - Syracuse, NY
Bus Wichita Falls, TX to Syracuse, NY Bus Wichita Falls, TX to Syracuse, NY
Bus The Woodlands, TX - Syracuse, NY Bus The Woodlands, TX - Syracuse, NY
Bus from Silver Spring, MD to Syracuse, NY Bus from Silver Spring, MD to Syracuse, NY
Bus Ashland, KY to Indianapolis Bus Ashland, KY to Indianapolis
Bus from Cedar City, UT to Indianapolis Bus from Cedar City, UT to Indianapolis
Bus Jackson, MI to Indianapolis Bus Jackson, MI to Indianapolis
Buses New Britain, CT to Indianapolis Buses New Britain, CT to Indianapolis
Popular Airport Shuttles to Syracuse, NY and to Indianapolis
CheckMyBus › Buses in USA › Bus to Syracuse, NY › Bus to Indianapolis

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.