Compare all timetables for the bus from Knoxville, TN to Indianapolis
Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Indianapolis from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 17h 0m | 7:05 PM | Knoxville, TN | Greyhound Bus Station | 12:05 PM | Indianapolis | Central Bus Station | Economy | $124 |
A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/21/2025 7:05:00 PM to Central Bus Station, Indianapolis (USA) arriving at 12/22/2025 12:05:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 17h 0m
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| Greyhound US | 10h 35m | 6:10 PM | Knoxville, TN | Greyhound Bus Station | 4:45 AM | Indianapolis | Central Bus Station | Economy | $125 |
A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/21/2025 6:10:00 PM to Central Bus Station, Indianapolis (USA) arriving at 12/22/2025 4:45:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 10h 35m
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| Greyhound US | 14h 15m | 6:10 PM | Knoxville, TN | Greyhound Bus Station | 8:25 AM | Indianapolis | Washington / Delaware | Economy | $129 |
A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/21/2025 6:10:00 PM to Washington / Delaware, Indianapolis (USA) arriving at 12/22/2025 8:25:00 AM. 50 Economy ticket for $129 per person are available. Travel duration is 14h 15m
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Best Price Offer: The price for the cheapest bus from Knoxville, TN to Indianapolis is $89 on 12/15/2025. Flexible travelers save on ticket prices.
Facts about the bus from Knoxville, TN to Indianapolis
Compare all providers like Greyhound US that travel 3 times every day by bus from Knoxville, TN to Indianapolis in one click! Book your bus ticket from Knoxville, TN to Indianapolis starting from $89!
| Cheapest Bus | $89 |
| Fastest Bus | 10h 35m |
| Earliest Bus | 6:10 PM |
| Latest Bus | 7:05 PM |
| Daily Bus Routes | 3 Ø |
| Distance | 289.8 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Knoxville, TN to Indianapolis
Every day, 3 buses from 1 bus companies leave Knoxville, TN for Indianapolis: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
$124
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
Sunday
12/28
Monday
12/29
Tuesday
12/30
Wednesday
12/31
Thursday
01/01
Friday
01/02
Saturday
01/03
Sunday
01/04
$110
Monday
01/05
Tuesday
01/06
Wednesday
01/07
Thursday
01/08
Friday
01/09
Saturday
01/10
How to save money travelling from Knoxville, TN to Indianapolis
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Knoxville, TN to Indianapolis in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Indianapolis, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Indianapolis are also emptier.Beloved bus companies from Knoxville, TN to Indianapolis
These are the most booked bus companies between Knoxville, TN to Indianapolis from our users.
Greyhound US from Knoxville, TN to Indianapolis
Here you will find the key facts about the Greyhound US bus route Knoxville, TN to Indianapolis:
| Cheapest Price | $124 |
| Fastest Bus | 10h 35m |
| Earliest Bus | 6:10 PM |
| Last Bus | 7:05 PM |
| Daily Connections | 3 Ø |
| Found on | 12/13/2025 |
All bus stations and stops in Knoxville, TN and Indianapolis
In the map below, you can see where to find all bus stations in Knoxville, TN and Indianapolis.
Service and Comfort on the bus from Knoxville, TN to Indianapolis
Want to know which seat classes are available on the buses from Knoxville, TN to Indianapolis? Or which bus companies serve the route Knoxville, TN to Indianapolis? Below you will find answers to your questions.
FAQs about the Knoxville, TN to Indianapolis bus
How much does a Knoxville, TN Indianapolis bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $89 and takes 17h 0m to reach Indianapolis. Compare offers to save money!
How much could I save by comparing buses from Knoxville, TN to Indianapolis?
This route is offered by 1 companies with a range of ticket prices between $89 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Indianapolis.
On average, how many connections are available from Knoxville, TN to Indianapolis each day?
Every day, the Knoxville, TN to Indianapolis bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Knoxville, TN to Indianapolis take?
The fastest bus from Knoxville, TN to Indianapolis is offered by Greyhound US and takes 10h 35m. Bus tickets for this connection cost $125. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Knoxville, TN to Indianapolis?
The earliest bus arriving in Indianapolis from Knoxville, TN starts at 6:10 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Knoxville, TN to Indianapolis?
The latest bus trip departing from Knoxville, TN for Indianapolis starts at 7:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Knoxville, TN Indianapolis route?
When traveling by bus from Knoxville, TN to Indianapolis, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Knoxville, TN and Indianapolis?
You can check all the direct connections between Knoxville, TN and Indianapolis by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Knoxville, TN to Indianapolis bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Indianapolis bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Knoxville, TN Indianapolis bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Indianapolis on your planned travel date.
How does CheckMyBus find the best bus deals from Knoxville, TN to Indianapolis?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Knoxville, TN and Indianapolis. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Knoxville, TN to Indianapolis?
Prices and availability for 3 trips between Knoxville, TN and Indianapolis change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Knoxville, TN to Indianapolis
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Knoxville, TN and to Indianapolis
Here’s an overview of the most popular bus routes to Knoxville, TN and to Indianapolis. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Knoxville, TN
- Bus Atlanta, GA to Knoxville, TN
- Bus from Baton Rouge to Knoxville, TN
- Bus from Beaumont, TX to Knoxville, TN
- Bus Birmingham, AL - Knoxville, TN
- Buses Gainesville, FL - Knoxville, TN
- Buses to Knoxville, TN from Huntsville, AL
- Buses Jacksonville, FL to Knoxville, TN
- Bus from Lexington, KY to Knoxville, TN
- Buses from Louisville, KY to Knoxville, TN
- Bus Memphis - Knoxville, TN
- From Miami to Knoxville, TN bus
- Buses Nashville - Knoxville, TN
- Bus from New York to Knoxville, TN
- Buses Norcross, GA - Knoxville, TN
- Buses Richmond, VA - Knoxville, TN
- Buses Roanoke, VA - Knoxville, TN
- Buses to Knoxville, TN from San Bernardino, CA
- Bus Schenectady, NY - Knoxville, TN
- Buses Warner Robins, GA to Knoxville, TN
- Buses Washington, DC - Knoxville, TN
- Bus Routes to Indianapolis
- Bus from Appleton, WI to Indianapolis
- From Birmingham, AL to Indianapolis bus
- Bus Bloomington, IN - Indianapolis
- Buses to Indianapolis from Boston, MA
- Buses from Dallas to Indianapolis
- Buses from Dayton, OH to Indianapolis
- Detroit to Indianapolis bus
- Buses from Gary, IN to Indianapolis
- Bus to Indianapolis from Gastonia, NC
- Bus Houston to Indianapolis
- Buses Madison, WI to Indianapolis
- Buses Memphis to Indianapolis
- Buses Myrtle Beach, SC - Indianapolis
- New Orleans, LA to Indianapolis bus
- Ottawa, ON to Indianapolis bus
- Bus from Palm Coast, FL to Indianapolis
- Bus to Indianapolis from Philadelphia
- From Richmond, VA to Indianapolis bus
- From South Bend, IN to Indianapolis bus
- Bus Toronto, ON to Indianapolis
Popular Airport Shuttles to Knoxville, TN and to Indianapolis
