Bus St. Louis, MO to San Antonio, TX: Compare prices and save money

Compare all timetables for the bus from St. Louis, MO to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to San Antonio, TX from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

from $99

Wednesday

from $100

Thursday

Friday

Saturday

Sunday

from $115

Cheapest bus trips tomorrow

Prices are for one way and one person

Greyhound US

22h 15m

0

1:35 AM

St. Louis, MO
Gateway Station

11:50 PM

San Antonio, TX
Bus Station

0

Economy

$99

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/15/2025 1:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/15/2025 11:50:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 22h 15m
FlixBus

29h 30m

0

11:30 PM

St. Louis, MO
Gateway Station

5:00 AM

San Antonio, TX
Bus Station

0

Economy

$100

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/15/2025 11:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/17/2025 5:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 29h 30m
FlixBus

20h 55m

0

4:00 PM

St. Louis, MO
Gateway Station

12:55 PM

San Antonio, TX
Bus Station

0

Economy

$102

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/15/2025 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/16/2025 12:55:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 20h 55m
Greyhound US

21h 25m

0

7:35 AM

St. Louis, MO
Gateway Station

5:00 AM

San Antonio, TX
Bus Station

0

Economy

$106

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/15/2025 7:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/16/2025 5:00:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 21h 25m
Greyhound US

25h 5m

0

4:30 PM

St. Louis, MO
Gateway Station

5:35 PM

San Antonio, TX
Bus Station

0

Economy

$120

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/15/2025 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/16/2025 5:35:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 25h 5m

Cheapest bus trips Wednesday

Prices are for one way and one person

Greyhound US

22h 15m

0

1:35 AM

St. Louis, MO
Gateway Station

11:50 PM

San Antonio, TX
Bus Station

0

Economy

$100

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/16/2025 1:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/16/2025 11:50:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 22h 15m
Greyhound US

25h 5m

0

4:30 PM

St. Louis, MO
Gateway Station

5:35 PM

San Antonio, TX
Bus Station

0

Economy

$100

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/16/2025 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/17/2025 5:35:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 25h 5m
FlixBus

29h 30m

0

11:30 PM

St. Louis, MO
Gateway Station

5:00 AM

San Antonio, TX
Bus Station

0

Economy

$100

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/16/2025 11:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/18/2025 5:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 29h 30m
FlixBus

20h 55m

0

4:00 PM

St. Louis, MO
Gateway Station

12:55 PM

San Antonio, TX
Bus Station

0

Economy

$137

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/16/2025 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/17/2025 12:55:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 20h 55m

Cheapest bus trips Sunday

Prices are for one way and one person

FlixBus

29h 30m

0

11:30 PM

St. Louis, MO
Gateway Station

5:00 AM

San Antonio, TX
Bus Station

0

Economy

$115

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/20/2025 11:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/22/2025 5:00:00 AM. 50 Economy ticket for $115 per person are available. Travel duration is 29h 30m
Greyhound US

22h 15m

0

1:35 AM

St. Louis, MO
Gateway Station

11:50 PM

San Antonio, TX
Bus Station

0

Economy

$120

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/20/2025 1:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/20/2025 11:50:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 22h 15m
Greyhound US

25h 5m

0

4:30 PM

St. Louis, MO
Gateway Station

5:35 PM

San Antonio, TX
Bus Station

0

Economy

$122

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/20/2025 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/21/2025 5:35:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 25h 5m
FlixBus

20h 55m

0

4:00 PM

St. Louis, MO
Gateway Station

12:55 PM

San Antonio, TX
Bus Station

0

Economy

$123

A Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 7/20/2025 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 7/21/2025 12:55:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 20h 55m
Greyhound US

21h 25m

0

7:35 AM

St. Louis, MO
Gateway Station

5:00 AM

San Antonio, TX
Bus Station

0

Economy

$125

A Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 7/20/2025 7:35:00 AM to Bus Station, San Antonio, TX (USA) arriving at 7/21/2025 5:00:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 21h 25m
Did you know that if you travel from St. Louis, MO to San Antonio, TX via Austin, you can save more than $11? You can find the corresponding connections below.
- Busbud
  
  23h 55m
  
  0
  
  4:00 PM
  
  St. Louis, MO
  Gateway Station
  
  11:00 AM
  
  Austin
  5119 Eastside Bus Plaza
  
  0
  
  Economy
  
  $87
  
  A Bus from Busbud goes from Gateway Station, St. Louis, MO (USA) at 7/19/2025 4:00:00 PM to 5119 Eastside Bus Plaza, Austin (USA) arriving at 7/20/2025 11:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 0m
- FlixBus
  
  2h 15m
  
  0
  
  1:40 PM
  
  Austin
  North Austin/The Domain
  
  3:55 PM
  
  San Antonio, TX
  Pearl District
  
  0
  
  Economy
  
  $17
  
  A Bus from FlixBus goes from North Austin/The Domain, Austin (USA) at 7/20/2025 1:40:00 PM to Pearl District, San Antonio, TX (USA) arriving at 7/20/2025 3:55:00 PM. 50 Economy ticket for $17 per person are available. Travel duration is 2h 15m
Travel time is 3h 0m longer, but you will save $11

Frequency of bus connections between St. Louis, MO and San Antonio, TX

See here how frequent the connections between St. Louis, MO and San Antonio, TX are, during different times and days of the week.

Sunday is the busiest day, with more than 5 daily buses from St. Louis, MO to San Antonio, TX. Wednesday has instead the fewest connections, with only 4 daily coaches between St. Louis, MO and San Antonio, TX.

The busiest time of the day is the Afternoon, with 6 buses from St. Louis, MO to San Antonio, TX, while Morning sees the fewest connections between St. Louis, MO and San Antonio, TX, with 2 offers.

Facts about the bus from St. Louis, MO to San Antonio, TX

Compare all providers like Greyhound US and FlixBus that travel 4 times every day by bus from St. Louis, MO to San Antonio, TX in one click! Book your bus ticket from St. Louis, MO to San Antonio, TX starting from $99!

Cheapest Bus	$99
Fastest Bus	20h 55m
Earliest Bus	1:35 AM
Latest Bus	11:30 PM
Daily Bus Routes	4 Ø
Distance	792.3 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to San Antonio, TX

Every day, 4 buses from 2 bus companies leave St. Louis, MO for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/14/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/13

Monday 07/14

Tuesday 07/15

$99

Wednesday 07/16

$100

Thursday 07/17

Friday 07/18

Saturday 07/19

Sunday 07/20

$115

Monday 07/21

Tuesday 07/22

Wednesday 07/23

Thursday 07/24

Friday 07/25

$93

Saturday 07/26

Sunday 07/27

Monday 07/28

$107

Tuesday 07/29

Wednesday 07/30

Thursday 07/31

Friday 08/01

Saturday 08/02

Sunday 08/03

Monday 08/04

Tuesday 08/05

Wednesday 08/06

Thursday 08/07

$96

Friday 08/08

Saturday 08/09

The cheapest time to travel from St. Louis, MO to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to San Antonio, TX, for the next 30 days.

With a price starting from $99, Tuesday is the cheapest day for a bus from St. Louis, MO to San Antonio, TX. Sunday instead is the most expensive day with prices starting from $115.

Night is the cheapest day time for bus tickets from St. Louis, MO to San Antonio, TX, with $99. Morning is the most expensive time of the day with prices starting from $106.

How to save money travelling from St. Louis, MO to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to San Antonio, TX are also emptier.

Beloved bus companies from St. Louis, MO to San Antonio, TX

These are the most booked bus companies between St. Louis, MO to San Antonio, TX from our users.

Greyhound US from St. Louis, MO to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route St. Louis, MO to San Antonio, TX:

Cheapest Price	$99
Fastest Bus	21h 25m
Earliest Bus	1:35 AM
Last Bus	4:30 PM
Daily Connections	2 Ø
Found on	7/11/2025

FlixBus from St. Louis, MO to San Antonio, TX

Here you will find the key facts about the FlixBus bus route St. Louis, MO to San Antonio, TX:

Cheapest Price	$100
Fastest Bus	20h 55m
Earliest Bus	4:00 PM
Last Bus	11:30 PM
Daily Connections	2 Ø
Found on	7/11/2025

All bus stations and stops in St. Louis, MO and San Antonio, TX

In the map below, you can see where to find all bus stations in St. Louis, MO and San Antonio, TX.

Lindbergh @ Hackberry NB Bus Stop

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Gateway Station

S 15th St 430

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Urban Loop

W. Southcross & Buffalo Bus Stop

Service and Comfort on the bus from St. Louis, MO to San Antonio, TX

Want to know which seat classes are available on the buses from St. Louis, MO to San Antonio, TX? Or which bus companies serve the route St. Louis, MO to San Antonio, TX? Below you will find answers to your questions.

FAQs about the St. Louis, MO to San Antonio, TX bus

How much does a St. Louis, MO San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $99 and takes 22h 15m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $99 and $137. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from St. Louis, MO to San Antonio, TX each day?

Every day, the St. Louis, MO to San Antonio, TX bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to San Antonio, TX take?

The fastest bus from St. Louis, MO to San Antonio, TX is offered by FlixBus and takes 20h 55m. Bus tickets for this connection cost $102. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from St. Louis, MO starts at 1:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to San Antonio, TX?

The latest bus trip departing from St. Louis, MO for San Antonio, TX starts at 11:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO San Antonio, TX route?

When traveling by bus from St. Louis, MO to San Antonio, TX, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and San Antonio, TX?

You can check all the direct connections between St. Louis, MO and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to San Antonio, TX on your planned travel date.

Available seat classes which are offered on the bus route St. Louis, MO to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to San Antonio, TX

Here’s an overview of the most popular bus routes to St. Louis, MO and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!