Bus from St. Louis, MO to San Antonio, TX from $93

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Compare all timetables for the bus from St. Louis, MO to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to San Antonio, TX from various bus operators like Greyhound US or FlixBus for the next days.

today
$100
tomorrow
Tuesday
Wednesday
Thursday
$96
Friday
$114
Saturday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 55m 4:00 PM St. Louis, MO Gateway Station 12:55 PM San Antonio, TX Bus Station  Economy $100
Greyhound US 25h 5m 4:30 PM St. Louis, MO Gateway Station 5:35 PM San Antonio, TX Bus Station  Economy $100
Greyhound US 30h 55m 4:30 PM St. Louis, MO Gateway Station 11:25 PM San Antonio, TX Pearl District  Economy $100
  • Did you know that if you travel from St. Louis, MO to San Antonio, TX via Dallas, you can save more than $17? You can find the corresponding connections below.
    • Greyhound US
      22h 5m
      0
      1:20 AM
      St. Louis, MO
      Gateway Station
      5:15 PM
      Dallas
      Harry Hines @ Webb Chapel Ext - S - MB
      0
      Greyhound US
      Economy
      $60
      • Waiting Time 0h 40m
    • FlixBus
      5h 30m
      0
      5:55 PM
      Dallas
      Downtown
      11:25 PM
      San Antonio, TX
      Pearl District
      0
      FlixBus
      Economy
      $23
    Travel time is 1h 10m longer, but you will save $17

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 35m 1:20 AM St. Louis, MO Gateway Station 11:55 PM San Antonio, TX Bus Station  Economy $96
Greyhound US 25h 5m 4:30 PM St. Louis, MO Gateway Station 5:35 PM San Antonio, TX Bus Station  Economy $96
FlixBus 20h 55m 4:00 PM St. Louis, MO Gateway Station 12:55 PM San Antonio, TX Bus Station  Economy $96
Greyhound US 23h 45m 1:30 AM St. Louis, MO Gateway Station 1:15 AM San Antonio, TX Bus Station  Economy $97
  • Did you know that if you travel from St. Louis, MO to San Antonio, TX via Dallas, you can save more than $13? You can find the corresponding connections below.
    • Greyhound US
      22h 5m
      0
      1:20 AM
      St. Louis, MO
      Gateway Station
      5:15 PM
      Dallas
      Harry Hines @ Webb Chapel Ext - S - MB
      0
      Greyhound US
      Economy
      $60
      • Waiting Time 0h 40m
    • FlixBus
      5h 30m
      0
      5:55 PM
      Dallas
      Downtown
      11:25 PM
      San Antonio, TX
      Pearl District
      0
      FlixBus
      Economy
      $23
    Travel time is 1h 10m longer, but you will save $13

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 25h 5m 4:30 PM St. Louis, MO Gateway Station 5:35 PM San Antonio, TX Bus Station  Economy $114
Greyhound US 28h 40m 4:30 PM St. Louis, MO Gateway Station 9:10 PM San Antonio, TX Pearl District  Economy $114
Greyhound US 22h 35m 1:20 AM St. Louis, MO Gateway Station 11:55 PM San Antonio, TX Bus Station  Economy $115
FlixBus 20h 55m 4:00 PM St. Louis, MO Gateway Station 12:55 PM San Antonio, TX Bus Station  Economy $115
  • Did you know that if you travel from St. Louis, MO to San Antonio, TX via Dallas, you can save more than $31? You can find the corresponding connections below.
    • Greyhound US
      22h 5m
      0
      1:20 AM
      St. Louis, MO
      Gateway Station
      5:15 PM
      Dallas
      Harry Hines @ Webb Chapel Ext - S - MB
      0
      Greyhound US
      Economy
      $60
      • Waiting Time 0h 40m
    • FlixBus
      5h 30m
      0
      5:55 PM
      Dallas
      Downtown
      11:25 PM
      San Antonio, TX
      Pearl District
      0
      FlixBus
      Economy
      $23
    Travel time is 1h 10m longer, but you will save $31

Best Price Offer: The price for the cheapest bus from St. Louis, MO to San Antonio, TX is $93 on 4/6/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between St. Louis, MO and San Antonio, TX

See here how frequent the connections between St. Louis, MO and San Antonio, TX are, during different times and days of the week.
Thursday is the busiest day, with more than 10 daily buses from St. Louis, MO to San Antonio, TX. Sunday has instead the fewest connections, with only 3 daily coaches between St. Louis, MO and San Antonio, TX.
The busiest time of the day is the Afternoon, with 12 buses from St. Louis, MO to San Antonio, TX, while Night sees the fewest connections between St. Louis, MO and San Antonio, TX, with 6 offers.

Facts about the bus from St. Louis, MO to San Antonio, TX

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from St. Louis, MO to San Antonio, TX in one click! Book your bus ticket from St. Louis, MO to San Antonio, TX starting from $93!

Cheapest Bus $93
Fastest Bus 20h 55m
Earliest Bus 4:00 PM
Latest Bus 4:30 PM
Daily Bus Routes 6 Ø
Distance 792.3 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to San Antonio, TX

Every day, 6 buses from 2 bus companies leave St. Louis, MO for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/22
$99
Monday 03/23
Tuesday 03/24
Wednesday 03/25
Thursday 03/26
$96
Friday 03/27
$114
Saturday 03/28
Sunday 03/29
$115
Monday 03/30
$105
Tuesday 03/31
$117
Wednesday 04/01
Thursday 04/02
$99
Friday 04/03
Saturday 04/04
$107
Sunday 04/05
$107
Monday 04/06
$93
Tuesday 04/07
Wednesday 04/08
$123
Thursday 04/09
Friday 04/10
$101
Saturday 04/11
$126
Sunday 04/12
$103
Monday 04/13
$107
Tuesday 04/14
Wednesday 04/15
$119
Thursday 04/16
$111
Friday 04/17
$111
Saturday 04/18

The cheapest time to travel from St. Louis, MO to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to San Antonio, TX, for the next 30 days.
With a price starting from $96, Thursday is the cheapest day for a bus from St. Louis, MO to San Antonio, TX. Friday instead is the most expensive day with prices starting from $101.
Night is the cheapest day time for bus tickets from St. Louis, MO to San Antonio, TX, with $93. Afternoon is the most expensive time of the day with prices starting from $96.

How to save money travelling from St. Louis, MO to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to San Antonio, TX are also emptier.

Beloved bus companies from St. Louis, MO to San Antonio, TX

These are the most booked bus companies between St. Louis, MO to San Antonio, TX from our users.

FlixBus from St. Louis, MO to San Antonio, TX

FlixBus

Here you will find the key facts about the FlixBus bus route St. Louis, MO to San Antonio, TX:

Cheapest Price $96
Fastest Bus 20h 55m
Earliest Bus 4:00 PM
Last Bus 4:00 PM
Daily Connections 1 Ø
Found on 3/1/2026

All bus stations and stops in St. Louis, MO and San Antonio, TX

In the map below, you can see where to find all bus stations in St. Louis, MO and San Antonio, TX.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from St. Louis, MO to San Antonio, TX? Compare all modes of transports from St. Louis, MO to San Antonio, TX.

Service and Comfort on the bus from St. Louis, MO to San Antonio, TX

Want to know which seat classes are available on the buses from St. Louis, MO to San Antonio, TX? Or which bus companies serve the route St. Louis, MO to San Antonio, TX? Below you will find answers to your questions.

FAQs about the St. Louis, MO to San Antonio, TX bus

How much does a St. Louis, MO San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $93 and takes 22h 35m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $93 and $115. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from St. Louis, MO to San Antonio, TX each day?

Every day, the St. Louis, MO to San Antonio, TX bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to San Antonio, TX take?

The fastest bus from St. Louis, MO to San Antonio, TX is offered by FlixBus and takes 20h 55m. Bus tickets for this connection cost $100. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from St. Louis, MO starts at 4:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to San Antonio, TX?

The latest bus trip departing from St. Louis, MO for San Antonio, TX starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO San Antonio, TX route?

When traveling by bus from St. Louis, MO to San Antonio, TX, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and San Antonio, TX?

You can check all the direct connections between St. Louis, MO and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between St. Louis, MO and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to San Antonio, TX?

Prices and availability for 6 trips between St. Louis, MO and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to San Antonio, TX

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to San Antonio, TX

Here’s an overview of the most popular bus routes to St. Louis, MO and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!
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CheckMyBus › Buses in USA › Bus to St. Louis, MO › Bus to San Antonio, TX

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