Bus from St. Louis, MO to Philadelphia from $64

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Compare all timetables for the bus from St. Louis, MO to Philadelphia

Here is a selection of the cheapest bus trips from the schedule from St. Louis, MO to Philadelphia from various bus operators like Greyhound US or FlixBus for the next days.

today
$101
tomorrow
$94
Tuesday
Wednesday
$64
Thursday
$86
Friday
Saturday
$92

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 25m 8:45 AM St. Louis, MO Gateway Station 8:10 AM Philadelphia Spring Garden St Station  Economy $101
Greyhound US 22h 5m 1:55 PM St. Louis, MO Gateway Station 1:00 PM Philadelphia Spring Garden St Station  Economy $104
FlixBus 29h 15m 9:30 AM St. Louis, MO Gateway Station 3:45 PM Philadelphia Spring Garden St Station  Economy $107
FlixBus 32h 15m 11:30 PM St. Louis, MO Gateway Station 8:45 AM Philadelphia Spring Garden St Station  Economy $107
Greyhound US 33h 35m 1:45 PM St. Louis, MO Gateway Station 12:20 AM Philadelphia Spring Garden St Station  Economy $108

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 50m 2:00 AM St. Louis, MO Gateway Station 1:50 AM Philadelphia Convention Center  Economy $94
Greyhound US 22h 25m 8:45 AM St. Louis, MO Gateway Station 8:10 AM Philadelphia Convention Center  Economy $94
Greyhound US 22h 5m 1:55 PM St. Louis, MO Gateway Station 1:00 PM Philadelphia Convention Center  Economy $94
FlixBus 30h 15m 11:30 PM St. Louis, MO Gateway Station 6:45 AM Philadelphia Convention Center  Economy $108
FlixBus 32h 15m 11:30 PM St. Louis, MO Gateway Station 8:45 AM Philadelphia Spring Garden St Station  Economy $108

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 25m 8:45 AM St. Louis, MO Gateway Station 8:10 AM Philadelphia Spring Garden St Station  Economy $64
Greyhound US 22h 50m 2:00 AM St. Louis, MO Gateway Station 1:50 AM Philadelphia Spring Garden St Station  Economy $66
Greyhound US 22h 5m 1:55 PM St. Louis, MO Gateway Station 1:00 PM Philadelphia Spring Garden St Station  Economy $69
FlixBus 29h 15m 9:30 AM St. Louis, MO Gateway Station 3:45 PM Philadelphia Spring Garden St Station  Economy $101
FlixBus 30h 15m 11:30 PM St. Louis, MO Gateway Station 6:45 AM Philadelphia Spring Garden St Station  Economy $102

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 50m 2:00 AM St. Louis, MO Gateway Station 1:50 AM Philadelphia Convention Center  Economy $86
Greyhound US 22h 25m 8:45 AM St. Louis, MO Gateway Station 8:10 AM Philadelphia Convention Center  Economy $86
Greyhound US 22h 5m 1:55 PM St. Louis, MO Gateway Station 1:00 PM Philadelphia Convention Center  Economy $86
FlixBus 29h 15m 9:30 AM St. Louis, MO Gateway Station 3:45 PM Philadelphia Spring Garden St Station  Economy $100
FlixBus 30h 15m 11:30 PM St. Louis, MO Gateway Station 6:45 AM Philadelphia Convention Center  Economy $100

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 50m 2:00 AM St. Louis, MO Gateway Station 1:50 AM Philadelphia Convention Center  Economy $92
Greyhound US 22h 25m 8:45 AM St. Louis, MO Gateway Station 8:10 AM Philadelphia Convention Center  Economy $92
Greyhound US 22h 5m 1:55 PM St. Louis, MO Gateway Station 1:00 PM Philadelphia Convention Center  Economy $94
FlixBus 30h 0m 11:45 PM St. Louis, MO Gateway Station 6:45 AM Philadelphia Spring Garden St Station  Economy $152
FlixBus 32h 0m 11:45 PM St. Louis, MO Gateway Station 8:45 AM Philadelphia Spring Garden St Station  Economy $153

Best Price Offer: The price for the cheapest bus from St. Louis, MO to Philadelphia is $64 on 3/25/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between St. Louis, MO and Philadelphia

See here how frequent the connections between St. Louis, MO and Philadelphia are, during different times and days of the week.
Thursday is the busiest day, with more than 14 daily buses from St. Louis, MO to Philadelphia. Sunday has instead the fewest connections, with only 6 daily coaches between St. Louis, MO and Philadelphia.
The busiest time of the day is the Afternoon, with 16 buses from St. Louis, MO to Philadelphia, while Night sees the fewest connections between St. Louis, MO and Philadelphia, with 7 offers.

Facts about the bus from St. Louis, MO to Philadelphia

Compare all providers like Greyhound US and FlixBus that travel 10 times every day by bus from St. Louis, MO to Philadelphia in one click! Book your bus ticket from St. Louis, MO to Philadelphia starting from $64!

Cheapest Bus $64
Fastest Bus 23h 5m
Earliest Bus 8:45 AM
Latest Bus 11:45 PM
Daily Bus Routes 10 Ø
Distance 807.9 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from St. Louis, MO to Philadelphia

Every day, 10 buses from 2 bus companies leave St. Louis, MO for Philadelphia: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/22
$101
Monday 03/23
$94
Tuesday 03/24
Wednesday 03/25
$64
Thursday 03/26
$86
Friday 03/27
Saturday 03/28
$92
Sunday 03/29
Monday 03/30
Tuesday 03/31
Wednesday 04/01
$93
Thursday 04/02
$85
Friday 04/03
Saturday 04/04
$85
Sunday 04/05
Monday 04/06
$83
Tuesday 04/07
$79
Wednesday 04/08
$83
Thursday 04/09
$79
Friday 04/10
$83
Saturday 04/11
$85
Sunday 04/12
$87
Monday 04/13
$82
Tuesday 04/14
Wednesday 04/15
Thursday 04/16
$79
Friday 04/17
$83
Saturday 04/18

The cheapest time to travel from St. Louis, MO to Philadelphia

See here on which day and which time of the day you can find the cheapest bus ticket from St. Louis, MO to Philadelphia, for the next 30 days.
With a price starting from $64, Wednesday is the cheapest day for a bus from St. Louis, MO to Philadelphia. Sunday instead is the most expensive day with prices starting from $87.
Morning is the cheapest day time for bus tickets from St. Louis, MO to Philadelphia, with $64. Evening is the most expensive time of the day with prices starting from $100.

How to save money travelling from St. Louis, MO to Philadelphia

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from St. Louis, MO to Philadelphia in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from St. Louis, MO to Philadelphia, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from St. Louis, MO to Philadelphia are also emptier.

All bus stations and stops in St. Louis, MO and Philadelphia

In the map below, you can see where to find all bus stations in St. Louis, MO and Philadelphia.

Service and Comfort on the bus from St. Louis, MO to Philadelphia

Want to know which seat classes are available on the buses from St. Louis, MO to Philadelphia? Or which bus companies serve the route St. Louis, MO to Philadelphia? Below you will find answers to your questions.

FAQs about the St. Louis, MO to Philadelphia bus

How much does a St. Louis, MO Philadelphia bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $64 and takes 23h 25m to reach Philadelphia. Compare offers to save money!

How much could I save by comparing buses from St. Louis, MO to Philadelphia?

This route is offered by 2 companies with a range of ticket prices between $64 and $165. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Philadelphia.

On average, how many connections are available from St. Louis, MO to Philadelphia each day?

Every day, the St. Louis, MO to Philadelphia bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from St. Louis, MO to Philadelphia take?

The fastest bus from St. Louis, MO to Philadelphia is offered by Greyhound US and takes 23h 5m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from St. Louis, MO to Philadelphia?

The earliest bus arriving in Philadelphia from St. Louis, MO starts at 8:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from St. Louis, MO to Philadelphia?

The latest bus trip departing from St. Louis, MO for Philadelphia starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the St. Louis, MO Philadelphia route?

When traveling by bus from St. Louis, MO to Philadelphia, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between St. Louis, MO and Philadelphia?

You can check all the direct connections between St. Louis, MO and Philadelphia by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the St. Louis, MO to Philadelphia bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the St. Louis, MO Philadelphia bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the St. Louis, MO Philadelphia bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from St. Louis, MO to Philadelphia on your planned travel date.

How does CheckMyBus find the best bus deals from St. Louis, MO to Philadelphia?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between St. Louis, MO and Philadelphia. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from St. Louis, MO to Philadelphia?

Prices and availability for 10 trips between St. Louis, MO and Philadelphia change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route St. Louis, MO to Philadelphia

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to St. Louis, MO and to Philadelphia

Here’s an overview of the most popular bus routes to St. Louis, MO and to Philadelphia. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to St. Louis, MO and to Philadelphia
CheckMyBus › Buses in USA › Bus to St. Louis, MO › Bus to Philadelphia

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