Compare all timetables for the bus from Knoxville, TN to Philadelphia
Cheapest bus trips today
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Greyhound US18h 45m010:50 PMKnoxville, TNGreyhound Bus Station5:35 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/17/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/18/2025 5:35:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 18h 45m
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Greyhound US16h 10m010:50 PMKnoxville, TNGreyhound Bus Station3:00 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/17/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/18/2025 3:00:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 16h 10m
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Greyhound US22h 20m010:50 PMKnoxville, TNGreyhound Bus Station9:10 PMPhiladelphiaIRS Building0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/17/2025 10:50:00 PM to IRS Building, Philadelphia (USA) arriving at 6/18/2025 9:10:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 20m
Cheapest bus trips tomorrow
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Greyhound US18h 45m010:50 PMKnoxville, TNGreyhound Bus Station5:35 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/18/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/19/2025 5:35:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 18h 45m
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Greyhound US20h 45m010:50 PMKnoxville, TNGreyhound Bus Station7:35 PMPhiladelphiaJFK & Broad0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/18/2025 10:50:00 PM to JFK & Broad, Philadelphia (USA) arriving at 6/19/2025 7:35:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 20h 45m
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Greyhound US16h 10m010:50 PMKnoxville, TNGreyhound Bus Station3:00 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/18/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/19/2025 3:00:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 16h 10m
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Greyhound US22h 20m010:50 PMKnoxville, TNGreyhound Bus Station9:10 PMPhiladelphiaIRS Building0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/18/2025 10:50:00 PM to IRS Building, Philadelphia (USA) arriving at 6/19/2025 9:10:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 22h 20m
Cheapest bus trips Friday
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Greyhound US22h 20m010:50 PMKnoxville, TNGreyhound Bus Station9:10 PMPhiladelphiaIRS Building0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/20/2025 10:50:00 PM to IRS Building, Philadelphia (USA) arriving at 6/21/2025 9:10:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 22h 20m
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Greyhound US16h 10m010:50 PMKnoxville, TNGreyhound Bus Station3:00 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/20/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/21/2025 3:00:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 16h 10m
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Greyhound US20h 45m010:50 PMKnoxville, TNGreyhound Bus Station7:35 PMPhiladelphiaJFK & Broad0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/20/2025 10:50:00 PM to JFK & Broad, Philadelphia (USA) arriving at 6/21/2025 7:35:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 20h 45m
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Greyhound US18h 45m010:50 PMKnoxville, TNGreyhound Bus Station5:35 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/20/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/21/2025 5:35:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 18h 45m
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FlixBus21h 15m010:50 PMKnoxville, TNGreyhound Bus Station3:45 PMSilver Spring, MDBus Stop0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/21/2025 10:50:00 PM to Bus Stop, Silver Spring, MD (USA) arriving at 6/22/2025 3:45:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 55m
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megabus US3h 25m04:40 PMSilver Spring, MDCentral Bus Station8:05 PMPhiladelphia520 N Christopher Columbus Blvd. Bus Stop0EconomyA Bus from megabus US goes from Central Bus Station, Silver Spring, MD (USA) at 6/22/2025 4:40:00 PM to 520 N Christopher Columbus Blvd. Bus Stop, Philadelphia (USA) arriving at 6/22/2025 8:05:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 3h 25m
Waiting Time 0h 55m -
Cheapest bus trips Monday
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Greyhound US16h 10m010:50 PMKnoxville, TNGreyhound Bus Station3:00 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/23/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/24/2025 3:00:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 16h 10m
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Greyhound US18h 45m010:50 PMKnoxville, TNGreyhound Bus Station5:35 PMPhiladelphiaSpring Garden St & 2nd St Bus Stop0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/23/2025 10:50:00 PM to Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) arriving at 6/24/2025 5:35:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 18h 45m
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Greyhound US22h 20m010:50 PMKnoxville, TNGreyhound Bus Station9:10 PMPhiladelphiaIRS Building0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/23/2025 10:50:00 PM to IRS Building, Philadelphia (USA) arriving at 6/24/2025 9:10:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 22h 20m
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FlixBus21h 15m010:50 PMKnoxville, TNGreyhound Bus Station3:45 PMSilver Spring, MDBus Stop0EconomyA Bus from FlixBus goes from Greyhound Bus Station, Knoxville, TN (USA) at 6/21/2025 10:50:00 PM to Bus Stop, Silver Spring, MD (USA) arriving at 6/22/2025 3:45:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 55m
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megabus US3h 25m04:40 PMSilver Spring, MDCentral Bus Station8:05 PMPhiladelphia520 N Christopher Columbus Blvd. Bus Stop0EconomyA Bus from megabus US goes from Central Bus Station, Silver Spring, MD (USA) at 6/22/2025 4:40:00 PM to 520 N Christopher Columbus Blvd. Bus Stop, Philadelphia (USA) arriving at 6/22/2025 8:05:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 3h 25m
Waiting Time 0h 55m -
Facts about the bus from Knoxville, TN to Philadelphia
Compare all providers like Greyhound US that travel 3 times every day by bus from Knoxville, TN to Philadelphia in one click! Book your bus ticket from Knoxville, TN to Philadelphia starting from $97!
Cheapest Bus | $97 |
Fastest Bus | 16h 10m |
Earliest Bus | 10:50 PM |
Latest Bus | 10:50 PM |
Daily Bus Routes | 3 Ø |
Distance | 549.6 miles |
Bus Companies | Greyhound US |
Cheapest bus connections from Knoxville, TN to Philadelphia
Every day, 3 buses from 1 bus companies leave Knoxville, TN for Philadelphia: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/17/2025 and for the following days.
How to save money travelling from Knoxville, TN to Philadelphia
Book the ticket from Knoxville, TN to Philadelphia in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Philadelphia, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Philadelphia are also emptier.All bus stations and stops in Knoxville, TN and Philadelphia
In the map below, you can see where to find all bus stations in Knoxville, TN and Philadelphia.
Service and Comfort on the bus from Knoxville, TN to Philadelphia
FAQs about the Knoxville, TN to Philadelphia bus
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Available seat classes which are offered on the bus route Knoxville, TN to Philadelphia
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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