Bus Knoxville, TN to Philadelphia - Compare all Companies

Compare all timetables for the bus from Knoxville, TN to Philadelphia

Here is a selection of the cheapest bus trips from the schedule from Knoxville, TN to Philadelphia from various bus operators like Greyhound US for the next days.

today

tomorrow

Saturday

$136

Sunday

$145

Monday

$139

Tuesday

Wednesday

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	20h 45m	10:50 PM	Knoxville, TN	Greyhound Bus Station	7:35 PM	Philadelphia	JFK & Broad	Economy	$136	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/27/2025 10:50:00 PM to JFK & Broad, Philadelphia (USA) arriving at 12/28/2025 7:35:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 20h 45m
Greyhound US	16h 10m	10:50 PM	Knoxville, TN	Greyhound Bus Station	3:00 PM	Philadelphia	Spring Garden St Station	Economy	$137	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/27/2025 10:50:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 12/28/2025 3:00:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 16h 10m
Greyhound US	16h 55m	10:50 PM	Knoxville, TN	Greyhound Bus Station	3:45 PM	Philadelphia	Spring Garden St Station	Economy	$137	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/27/2025 10:50:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 12/28/2025 3:45:00 PM. 50 Economy ticket for $137 per person are available. Travel duration is 16h 55m
Greyhound US	22h 5m	10:50 PM	Knoxville, TN	Greyhound Bus Station	8:55 PM	Philadelphia	IRS Building	Economy	$138	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/27/2025 10:50:00 PM to IRS Building, Philadelphia (USA) arriving at 12/28/2025 8:55:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 22h 5m

Did you know that if you travel from Knoxville, TN to Philadelphia via Washington, DC, you can save more than $40? You can find the corresponding connections below.
- Busbud
  
  21h 15m
  
  0
  
  10:50 PM
  
  Knoxville, TN
  Knoxville Area Transit Bus Stop
  
  10:20 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $82
  
  A Bus from Busbud goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 12/28/2025 10:50:00 PM to Union Station, Washington, DC (USA) arriving at 12/29/2025 10:20:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 11h 30m
- Distribusion
  
  4h 10m
  
  0
  
  3:55 PM
  
  Washington, DC
  Union Station
  
  8:05 PM
  
  Philadelphia
  520 N Christopher Columbus Blvd. Bus Stop
  
  0
  
  Economy
  
  $14
  
  A Bus from Distribusion goes from Union Station, Washington, DC (USA) at 12/29/2025 3:55:00 PM to 520 N Christopher Columbus Blvd. Bus Stop, Philadelphia (USA) arriving at 12/29/2025 8:05:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 10m
Travel time is 5h 5m longer, but you will save $40

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 55m	10:50 PM	Knoxville, TN	Greyhound Bus Station	3:45 PM	Philadelphia	Spring Garden St Station	Economy	$145	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/28/2025 10:50:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 12/29/2025 3:45:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 16h 55m
Greyhound US	20h 45m	10:50 PM	Knoxville, TN	Greyhound Bus Station	7:35 PM	Philadelphia	JFK & Broad	Economy	$147	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/28/2025 10:50:00 PM to JFK & Broad, Philadelphia (USA) arriving at 12/29/2025 7:35:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 20h 45m
Greyhound US	20h 55m	10:50 PM	Knoxville, TN	Greyhound Bus Station	7:45 PM	Philadelphia	IRS Building	Economy	$147	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/28/2025 10:50:00 PM to IRS Building, Philadelphia (USA) arriving at 12/29/2025 7:45:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 20h 55m
Greyhound US	16h 15m	10:50 PM	Knoxville, TN	Greyhound Bus Station	3:05 PM	Philadelphia	Spring Garden St Station	Economy	$148	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/28/2025 10:50:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 12/29/2025 3:05:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 16h 15m

Did you know that if you travel from Knoxville, TN to Philadelphia via Washington, DC, you can save more than $49? You can find the corresponding connections below.
- Busbud
  
  21h 15m
  
  0
  
  10:50 PM
  
  Knoxville, TN
  Knoxville Area Transit Bus Stop
  
  10:20 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $82
  
  A Bus from Busbud goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 12/28/2025 10:50:00 PM to Union Station, Washington, DC (USA) arriving at 12/29/2025 10:20:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 11h 30m
- Distribusion
  
  4h 10m
  
  0
  
  3:55 PM
  
  Washington, DC
  Union Station
  
  8:05 PM
  
  Philadelphia
  520 N Christopher Columbus Blvd. Bus Stop
  
  0
  
  Economy
  
  $14
  
  A Bus from Distribusion goes from Union Station, Washington, DC (USA) at 12/29/2025 3:55:00 PM to 520 N Christopher Columbus Blvd. Bus Stop, Philadelphia (USA) arriving at 12/29/2025 8:05:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 10m
Travel time is 5h 0m longer, but you will save $49

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 15m	10:50 PM	Knoxville, TN	Greyhound Bus Station	3:05 PM	Philadelphia	Spring Garden St Station	Economy	$139	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/29/2025 10:50:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 12/30/2025 3:05:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 16h 15m
Greyhound US	16h 55m	10:50 PM	Knoxville, TN	Greyhound Bus Station	3:45 PM	Philadelphia	Spring Garden St Station	Economy	$139	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/29/2025 10:50:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 12/30/2025 3:45:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 16h 55m
Greyhound US	22h 5m	10:50 PM	Knoxville, TN	Greyhound Bus Station	8:55 PM	Philadelphia	IRS Building	Economy	$141	A Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 12/29/2025 10:50:00 PM to IRS Building, Philadelphia (USA) arriving at 12/30/2025 8:55:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 22h 5m

Did you know that if you travel from Knoxville, TN to Philadelphia via Washington, DC, you can save more than $43? You can find the corresponding connections below.
- Busbud
  
  21h 15m
  
  0
  
  10:50 PM
  
  Knoxville, TN
  Knoxville Area Transit Bus Stop
  
  10:20 AM
  
  Washington, DC
  Union Station
  
  0
  
  Economy
  
  $82
  
  A Bus from Busbud goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 12/28/2025 10:50:00 PM to Union Station, Washington, DC (USA) arriving at 12/29/2025 10:20:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 11h 30m
- Distribusion
  
  4h 10m
  
  0
  
  3:55 PM
  
  Washington, DC
  Union Station
  
  8:05 PM
  
  Philadelphia
  520 N Christopher Columbus Blvd. Bus Stop
  
  0
  
  Economy
  
  $14
  
  A Bus from Distribusion goes from Union Station, Washington, DC (USA) at 12/29/2025 3:55:00 PM to 520 N Christopher Columbus Blvd. Bus Stop, Philadelphia (USA) arriving at 12/29/2025 8:05:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 4h 10m
Travel time is 5h 0m longer, but you will save $43

Best Price Offer: The price for the cheapest bus from Knoxville, TN to Philadelphia is $86 on 1/10/2026. Flexible travelers save on ticket prices.

Facts about the bus from Knoxville, TN to Philadelphia

Compare all providers like Greyhound US that travel 3 times every day by bus from Knoxville, TN to Philadelphia in one click! Book your bus ticket from Knoxville, TN to Philadelphia starting from $86!

Cheapest Bus	$86
Fastest Bus	16h 10m
Earliest Bus	10:50 PM
Latest Bus	10:50 PM
Daily Bus Routes	3 Ø
Distance	549.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Knoxville, TN to Philadelphia

Every day, 3 buses from 1 bus companies leave Knoxville, TN for Philadelphia: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/25/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

$136

Sunday 12/28

$145

Monday 12/29

$139

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

$134

Saturday 01/03

Sunday 01/04

$141

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

$86

Sunday 01/11

Monday 01/12

Tuesday 01/13

Wednesday 01/14

Thursday 01/15

Friday 01/16

Saturday 01/17

How to save money travelling from Knoxville, TN to Philadelphia

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Knoxville, TN to Philadelphia in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Knoxville, TN to Philadelphia, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Knoxville, TN to Philadelphia are also emptier.

All bus stations and stops in Knoxville, TN and Philadelphia

In the map below, you can see where to find all bus stations in Knoxville, TN and Philadelphia.

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Central Bus Station

Filbert St 1001

Market St

Spring Garden St Station

Spring Garden St & 2nd St

JFK & Broad

John F Kennedy Blvd 1401

30th Street Station

Market St 2955

Service and Comfort on the bus from Knoxville, TN to Philadelphia

Want to know which seat classes are available on the buses from Knoxville, TN to Philadelphia? Or which bus companies serve the route Knoxville, TN to Philadelphia? Below you will find answers to your questions.

FAQs about the Knoxville, TN to Philadelphia bus

How much does a Knoxville, TN Philadelphia bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $86 and takes 20h 45m to reach Philadelphia. Compare offers to save money!

How much could I save by comparing buses from Knoxville, TN to Philadelphia?

This route is offered by 1 companies with a range of ticket prices between $86 and $148. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Philadelphia.

On average, how many connections are available from Knoxville, TN to Philadelphia each day?

Every day, the Knoxville, TN to Philadelphia bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Knoxville, TN to Philadelphia take?

The fastest bus from Knoxville, TN to Philadelphia is offered by Greyhound US and takes 16h 10m. Bus tickets for this connection cost $137. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Knoxville, TN to Philadelphia?

The earliest bus arriving in Philadelphia from Knoxville, TN starts at 10:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Knoxville, TN to Philadelphia?

The latest bus trip departing from Knoxville, TN for Philadelphia starts at 10:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Knoxville, TN Philadelphia route?

When traveling by bus from Knoxville, TN to Philadelphia, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Knoxville, TN and Philadelphia?

You can check all the direct connections between Knoxville, TN and Philadelphia by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Knoxville, TN to Philadelphia bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Knoxville, TN Philadelphia bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Knoxville, TN Philadelphia bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Knoxville, TN to Philadelphia on your planned travel date.

How does CheckMyBus find the best bus deals from Knoxville, TN to Philadelphia?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Knoxville, TN and Philadelphia. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Knoxville, TN to Philadelphia?

Prices and availability for 3 trips between Knoxville, TN and Philadelphia change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Knoxville, TN to Philadelphia

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Knoxville, TN and to Philadelphia

Here’s an overview of the most popular bus routes to Knoxville, TN and to Philadelphia. Simply click on the connection of your choice, and you will find all the details about your bus route!