What is the best way to travel from Florence to Lyon?
Looking for a trip? Compare all the available Trains, Flights and Buses for the journey to Lyon from Florence. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Florence?
You can get to Lyon with just $34 by taking a Bus from Itabus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/12/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/12/2026 12:55:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 50m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/12/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/12/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/12/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 6/13/2026 1:20:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 11h 5m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/12/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/12/2026 10:40:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 10h 40m
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Volotea1h 20m010:35 AMFlorence AirportFlorence Airport11:55 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 10:35:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 11:55:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 1h 20m
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Vueling Airlines12h 55m09:00 AMFlorence AirportFlorence Airport9:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 9:00:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 9:55:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 12h 55m
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ITA Airways4h 20m07:00 PMFlorence AirportFlorence Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 7:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 11:20:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 4h 20m
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Brussels Airlines10h 35m011:45 AMFlorence AirportFlorence Airport10:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 11:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 10:20:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 10h 35m
Cheapest Buses Friday
Cheapest Flights Friday
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Itabus12h 30m011:55 AMFlorenceVilla Costanza Bus Station12:25 AMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/13/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/14/2026 12:25:00 AM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 12h 30m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/13/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/13/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/13/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 6/14/2026 1:20:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 11h 5m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/13/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/13/2026 10:40:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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Vueling Airlines11h 5m010:00 PMFlorence AirportFlorence Airport9:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 9:05:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 11h 5m
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Brussels Airlines24h 10m012:15 PMFlorence AirportFlorence Airport12:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 12:15:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 12:25:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 24h 10m
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ITA Airways4h 5m03:30 PMFlorence AirportFlorence Airport7:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 3:30:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/13/2026 7:35:00 PM. 50 Economy ticket for $202 per person are available. Travel duration is 4h 5m
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Air France16h 20m06:10 PMFlorence AirportFlorence Airport10:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 6:10:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 10:30:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 16h 20m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/14/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/14/2026 12:55:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/14/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/14/2026 12:55:00 PM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 11h 50m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/14/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 6/15/2026 1:20:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 11h 5m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/14/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/14/2026 10:40:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 40m
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Volotea6h 40m09:15 AMFlorence AirportFlorence Airport3:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 9:15:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 3:55:00 PM. 50 Economy ticket for $204 per person are available. Travel duration is 6h 40m
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Air Dolomiti5h 10m07:00 AMFlorence AirportFlorence Airport12:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 7:00:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 12:10:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 5h 10m
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Air France8h 20m01:05 PMFlorence AirportFlorence Airport9:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 1:05:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 9:25:00 PM. 50 Economy ticket for $292 per person are available. Travel duration is 8h 20m
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Iberia27h 25m08:20 PMFlorence AirportFlorence Airport11:45 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Iberia goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 8:20:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/15/2026 11:45:00 PM. 50 Economy ticket for $326 per person are available. Travel duration is 27h 25m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/15/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
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Itabus12h 30m011:55 AMFlorenceVilla Costanza Bus Station12:25 AMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/16/2026 12:25:00 AM. 50 Premium Economy ticket for $43 per person are available. Travel duration is 12h 30m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/15/2026 9:30:00 PM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 11h 10m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/16/2026 6:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 45m
Cheapest Buses Monday
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/16/2026 9:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/16/2026 9:30:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 11h 10m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/16/2026 12:55:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 50m
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FlixBus11h 40m09:05 PMFlorenceVilla Costanza Bus Station8:45 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 9:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/17/2026 8:45:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 40m
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Vueling Airlines24h 5m09:00 AMFlorence AirportFlorence Airport9:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 9:00:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 9:05:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 24h 5m
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Air Dolomiti7h 20m06:30 AMFlorence AirportFlorence Airport1:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 6:30:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/16/2026 1:50:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 7h 20m
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Brussels Airlines10h 35m011:45 AMFlorence AirportFlorence Airport10:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 11:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/16/2026 10:20:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 10h 35m
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SAS Scandinavian Airlines23h 25m07:55 PMFlorence AirportFlorence Airport7:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from SAS Scandinavian Airlines goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 7:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 7:20:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 23h 25m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/17/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/17/2026 9:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/17/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/17/2026 9:30:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 11h 10m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/17/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 6/18/2026 6:05:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 55m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/17/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/18/2026 6:30:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 11h 45m
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Vueling Airlines20h 10m01:10 PMFlorence AirportFlorence Airport9:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 1:10:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 9:20:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 20h 10m
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Brussels Airlines10h 35m011:45 AMFlorence AirportFlorence Airport10:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 11:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 10:20:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 10h 35m
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SAS Scandinavian Airlines7h 0m012:20 PMFlorence AirportFlorence Airport7:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from SAS Scandinavian Airlines goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 12:20:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 7:20:00 PM. 50 Economy ticket for $254 per person are available. Travel duration is 7h 0m
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Air Dolomiti21h 20m02:50 PMFlorence AirportFlorence Airport12:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 2:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 12:10:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 21h 20m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/18/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/18/2026 12:55:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 50m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/18/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/18/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/18/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/18/2026 10:40:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/18/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/19/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 11h 45m
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Volotea9h 25m09:15 AMFlorence AirportFlorence Airport6:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 9:15:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 6:40:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 9h 25m
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Vueling Airlines4h 20m09:00 AMFlorence AirportFlorence Airport1:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 9:00:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 1:20:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 4h 20m
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Brussels Airlines10h 35m011:45 AMFlorence AirportFlorence Airport10:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 11:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 10:20:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 10h 35m
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ITA Airways4h 5m07:00 PMFlorence AirportFlorence Airport11:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 7:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 11:05:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 4h 5m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Florence to Lyon?
You can get to Lyon from Florence in just 1h 20m with a Flight from Volotea. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Volotea1h 20m010:35 AMFlorence AirportFlorence Airport11:55 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 10:35:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 11:55:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 1h 20m
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ITA Airways4h 20m07:00 PMFlorence AirportFlorence Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 7:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 11:20:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 4h 20m
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SAS Scandinavian Airlines7h 0m012:20 PMFlorence AirportFlorence Airport7:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from SAS Scandinavian Airlines goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 12:20:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 7:20:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 7h 0m
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Brussels Airlines10h 35m011:45 AMFlorence AirportFlorence Airport10:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/12/2026 11:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/12/2026 10:20:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 10h 35m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/12/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/12/2026 10:40:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/12/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 6/13/2026 1:20:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 11h 5m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/12/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/12/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/12/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/13/2026 6:30:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 45m
Fastest Flights Friday
Fastest Buses Friday
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ITA Airways4h 5m03:30 PMFlorence AirportFlorence Airport7:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 3:30:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/13/2026 7:35:00 PM. 50 Economy ticket for $202 per person are available. Travel duration is 4h 5m
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Vueling Airlines11h 5m010:00 PMFlorence AirportFlorence Airport9:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 9:05:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 11h 5m
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Air France16h 20m06:10 PMFlorence AirportFlorence Airport10:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 6:10:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 10:30:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 16h 20m
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Aegean Airlines22h 50m06:15 PMFlorence AirportFlorence Airport5:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Aegean Airlines goes from Florence Airport, Florence Airport (Italy) at 6/13/2026 6:15:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 5:05:00 PM. 50 Economy ticket for $347 per person are available. Travel duration is 22h 50m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/13/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/13/2026 10:40:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/13/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 6/14/2026 6:05:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 55m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/13/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 6/14/2026 1:20:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 11h 5m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/13/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/13/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
Fastest Flights Saturday
Fastest Buses Saturday
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ITA Airways4h 25m07:00 PMFlorence AirportFlorence Airport11:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 7:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 11:25:00 PM. 50 Economy ticket for $333 per person are available. Travel duration is 4h 25m
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Air Dolomiti5h 10m07:00 AMFlorence AirportFlorence Airport12:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 7:00:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 12:10:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 5h 10m
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Volotea6h 40m09:15 AMFlorence AirportFlorence Airport3:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 9:15:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 3:55:00 PM. 50 Economy ticket for $204 per person are available. Travel duration is 6h 40m
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Air France8h 20m01:05 PMFlorence AirportFlorence Airport9:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 6/14/2026 1:05:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/14/2026 9:25:00 PM. 50 Economy ticket for $292 per person are available. Travel duration is 8h 20m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/14/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/14/2026 10:40:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 40m
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FlixBus10h 40m07:30 AMFlorenceVilla Costanza Bus Station6:10 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/14/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/14/2026 6:10:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/14/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 6/15/2026 1:20:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 11h 5m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/14/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/14/2026 12:55:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 50m
Fastest Flights Sunday
Fastest Buses Sunday
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/15/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/15/2026 9:30:00 PM. 50 Premium Economy ticket for $47 per person are available. Travel duration is 11h 10m
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FlixBus11h 40m09:05 PMFlorenceVilla Costanza Bus Station8:45 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 9:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/16/2026 8:45:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 40m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/15/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/16/2026 6:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 45m
Fastest Buses Monday
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Air Dolomiti7h 20m06:30 AMFlorence AirportFlorence Airport1:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 6:30:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/16/2026 1:50:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 7h 20m
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Brussels Airlines10h 35m011:45 AMFlorence AirportFlorence Airport10:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 11:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/16/2026 10:20:00 PM. 50 Economy ticket for $198 per person are available. Travel duration is 10h 35m
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SAS Scandinavian Airlines23h 25m07:55 PMFlorence AirportFlorence Airport7:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from SAS Scandinavian Airlines goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 7:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 7:20:00 PM. 50 Economy ticket for $261 per person are available. Travel duration is 23h 25m
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Vueling Airlines24h 5m09:00 AMFlorence AirportFlorence Airport9:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/16/2026 9:00:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 9:05:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 24h 5m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/16/2026 9:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/16/2026 9:30:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 11h 10m
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FlixBus11h 40m09:05 PMFlorenceVilla Costanza Bus Station8:45 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 9:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/17/2026 8:45:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 11h 40m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/16/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/16/2026 12:55:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 50m
Fastest Flights Tuesday
Fastest Buses Tuesday
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SAS Scandinavian Airlines7h 0m012:20 PMFlorence AirportFlorence Airport7:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from SAS Scandinavian Airlines goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 12:20:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 7:20:00 PM. 50 Economy ticket for $254 per person are available. Travel duration is 7h 0m
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Brussels Airlines10h 35m011:45 AMFlorence AirportFlorence Airport10:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 11:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 10:20:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 10h 35m
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KLM Cityhopper16h 20m06:30 AMFlorence AirportFlorence Airport10:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from KLM Cityhopper goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 6:30:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/17/2026 10:50:00 PM. 50 Economy ticket for $317 per person are available. Travel duration is 16h 20m
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Vueling Airlines20h 10m01:10 PMFlorence AirportFlorence Airport9:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/17/2026 1:10:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 9:20:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 20h 10m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/17/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 6/18/2026 6:05:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 55m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/17/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/17/2026 9:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/17/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/17/2026 9:30:00 PM. 50 Premium Economy ticket for $40 per person are available. Travel duration is 11h 10m
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FlixBus11h 40m09:05 PMFlorenceVilla Costanza Bus Station8:45 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/17/2026 9:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/18/2026 8:45:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 11h 40m
Fastest Flights Wednesday
Fastest Buses Wednesday
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ITA Airways4h 5m07:00 PMFlorence AirportFlorence Airport11:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 7:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 11:05:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 4h 5m
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Vueling Airlines4h 20m09:00 AMFlorence AirportFlorence Airport1:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 9:00:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 1:20:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 4h 20m
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SAS Scandinavian Airlines7h 0m012:20 PMFlorence AirportFlorence Airport7:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from SAS Scandinavian Airlines goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 12:20:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 7:20:00 PM. 50 Economy ticket for $251 per person are available. Travel duration is 7h 0m
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Volotea9h 25m09:15 AMFlorence AirportFlorence Airport6:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Volotea goes from Florence Airport, Florence Airport (Italy) at 6/18/2026 9:15:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 6/18/2026 6:40:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 9h 25m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/18/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/18/2026 10:40:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 6/18/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 6/19/2026 1:20:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 11h 5m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 6/18/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 6/18/2026 9:30:00 PM. 50 Premium Economy ticket for $41 per person are available. Travel duration is 11h 10m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 6/18/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 6/19/2026 6:30:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 11h 45m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Florence to Lyon
What are the most popular stations in Florence and Lyon?
In Florence, you will usually depart from Santa Maria Novella Central Station, Villa Costanza Bus Station or Piazzale Montelungo Bus Stop, while in Lyon you will be arriving at Part-Dieu Train Station, Perrache Train Station or Perrache Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Florence? With 9 connections between 4 Train, Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Florence and Lyon, you can pay as low as $34 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Volotea: you will get to Lyon in just 1h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Florence and Lyon are Itabus, FlixBus and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Florence and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Scandicci or to Caluire-et-Cuire, and look at flights from Florence Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Florence to Lyon?
The most popular companies between Florence and Lyon, are Itabus, FlixBus and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, FlixBus and BlaBlaCar Bus
Airlines: Vueling Airlines, Brussels Airlines, ITA Airways and 8 more.
All you need to know when you travel from Florence to Lyon
Check all information on comfort and services on all modes of transports from Florence to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Florence to Lyon
How can I reach Lyon from Florence?
Every day, there are on average 9 connections between Train, Flight and Bus, with which you can get to Lyon from Florence.
How far is Lyon from Florence?
The distance between Florence and Lyon is 343.2 miles.
What is the most ecofriendly mode of transport between Florence and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 19 kgs, a car 94 kgs, and a flight 136 kgs.
What is the cheapest mode of transport from Florence to Lyon?
You can get to Lyon with just $34 by taking a Bus from Itabus.
What is the fastest way to get from Florence to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 20m with a Flight from Volotea.
More routes to Florence and to Lyon
Looking for more options? Here you can see the most popular routes to Florence and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
