What is the best way to travel from Florence to Lyon?
Looking for a trip? Compare all the available Flights and Buses for the journey to Lyon from Florence. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Florence?
You can get to Lyon with just $21 by taking a Bus from Itabus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/5/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/5/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/5/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/5/2026 12:55:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 50m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/5/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 3/6/2026 1:20:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 5m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/5/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/5/2026 10:40:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/5/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 3/6/2026 6:05:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 10h 55m
Cheapest Buses Thursday
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/6/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/6/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/6/2026 10:40:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 10h 40m
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Itabus12h 30m011:55 AMFlorenceVilla Costanza Bus Station12:25 AMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/7/2026 12:25:00 AM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 12h 30m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/7/2026 6:30:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 11h 45m
Cheapest Buses Friday
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/7/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/7/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/7/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/7/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/7/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 3/8/2026 1:20:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 5m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/7/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/7/2026 10:40:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/7/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 3/8/2026 6:05:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 55m
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Vueling Airlines6h 5m012:55 PMFlorence AirportFlorence Airport7:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 12:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 7:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 6h 5m
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ITA Airways5h 40m06:30 AMFlorence AirportFlorence Airport12:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 6:30:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 12:10:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 5h 40m
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Air Dolomiti9h 5m02:15 PMFlorence AirportFlorence Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 2:15:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 11:20:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 9h 5m
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Air France13h 5m08:45 PMFlorence AirportFlorence Airport9:50 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 8:45:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/8/2026 9:50:00 AM. 50 Economy ticket for $181 per person are available. Travel duration is 13h 5m
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Skyscanner11h 35m012:20 PMFlorence AirportFlorence Airport11:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 12:20:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 11:55:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 11h 35m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/8/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/8/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/8/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/8/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/8/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/8/2026 10:40:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/8/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 3/9/2026 1:20:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 5m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/8/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 3/9/2026 6:05:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 55m
Cheapest Buses Sunday
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/9/2026 9:30:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 11h 10m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/9/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/9/2026 10:40:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 10h 40m
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FlixBus10h 40m07:30 AMFlorenceVilla Costanza Bus Station6:10 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/9/2026 6:10:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 6:30:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 11h 45m
Cheapest Buses Monday
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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FlixBus11h 15m012:30 PMFlorenceVilla Costanza Bus Station11:45 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 12:30:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 11:45:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 15m
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FlixBus10h 40m07:30 AMFlorenceVilla Costanza Bus Station6:10 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 6:10:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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FlixBus11h 55m012:05 AMFlorenceVilla Costanza Bus Station12:00 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 12:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 12:00:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 55m
Cheapest Buses Tuesday
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/11/2026 12:55:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 50m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/11/2026 9:30:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/11/2026 9:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
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FlixBus10h 40m07:30 AMFlorenceVilla Costanza Bus Station6:10 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/11/2026 6:10:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 40m
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FlixBus11h 15m012:30 PMFlorenceVilla Costanza Bus Station11:45 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 12:30:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/11/2026 11:45:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 15m
Cheapest Buses Wednesday
What are the fastest trips from Florence to Lyon?
You can get to Lyon from Florence in just 5h 40m with a Flight from ITA Airways. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/5/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/5/2026 10:40:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/5/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 3/6/2026 6:05:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 10h 55m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/5/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 3/6/2026 1:20:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 5m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/5/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/5/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/5/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/5/2026 12:55:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 50m
Fastest Buses Thursday
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/6/2026 10:40:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/7/2026 6:30:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 11h 45m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/6/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/6/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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Itabus12h 30m011:55 AMFlorenceVilla Costanza Bus Station12:25 AMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/6/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/7/2026 12:25:00 AM. 50 Premium Economy ticket for $39 per person are available. Travel duration is 12h 30m
Fastest Buses Friday
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ITA Airways5h 40m06:30 AMFlorence AirportFlorence Airport12:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from ITA Airways goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 6:30:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 12:10:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 5h 40m
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Vueling Airlines6h 5m012:55 PMFlorence AirportFlorence Airport7:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Vueling Airlines goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 12:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 7:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 6h 5m
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Air Dolomiti9h 5m02:15 PMFlorence AirportFlorence Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 2:15:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 11:20:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 9h 5m
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Skyscanner11h 35m012:20 PMFlorence AirportFlorence Airport11:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 12:20:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/7/2026 11:55:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 11h 35m
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Air France13h 5m08:45 PMFlorence AirportFlorence Airport9:50 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air France goes from Florence Airport, Florence Airport (Italy) at 3/7/2026 8:45:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/8/2026 9:50:00 AM. 50 Economy ticket for $181 per person are available. Travel duration is 13h 5m
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/7/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/7/2026 10:40:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/7/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 3/8/2026 6:05:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 55m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/7/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 3/8/2026 1:20:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 5m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/7/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/7/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/7/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/7/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/8/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/8/2026 10:40:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus10h 55m07:10 PMFlorencePiazza della Stazione Bus Station6:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/8/2026 7:10:00 PM to Perrache Train Station, Lyon (France) arriving at 3/9/2026 6:05:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 55m
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BlaBlaCar Bus11h 5m02:15 PMFlorencePiazza della Stazione Bus Station1:20 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Piazza della Stazione Bus Station, Florence (Italy) at 3/8/2026 2:15:00 PM to Perrache Train Station, Lyon (France) arriving at 3/9/2026 1:20:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 5m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/8/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/8/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/8/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/8/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
Fastest Buses Sunday
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FlixBus10h 40m012:00 PMFlorenceVilla Costanza Bus Station10:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 12:00:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/9/2026 10:40:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 10h 40m
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FlixBus10h 40m07:30 AMFlorenceVilla Costanza Bus Station6:10 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/9/2026 6:10:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/9/2026 9:30:00 PM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 11h 10m
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FlixBus11h 45m06:45 PMFlorenceVilla Costanza Bus Station6:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 6:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 6:30:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 11h 45m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/9/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/9/2026 12:55:00 PM. 50 Premium Economy ticket for $23 per person are available. Travel duration is 11h 50m
Fastest Buses Monday
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FlixBus10h 40m07:30 AMFlorenceVilla Costanza Bus Station6:10 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 6:10:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 10h 40m
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FlixBus11h 15m012:30 PMFlorenceVilla Costanza Bus Station11:45 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 12:30:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 11:45:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 15m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 12:55:00 PM. 50 Premium Economy ticket for $30 per person are available. Travel duration is 11h 50m
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FlixBus11h 55m012:05 AMFlorenceVilla Costanza Bus Station12:00 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/10/2026 12:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/10/2026 12:00:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 55m
Fastest Buses Tuesday
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FlixBus10h 40m07:30 AMFlorenceVilla Costanza Bus Station6:10 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/11/2026 6:10:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 10h 40m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 10:20:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/11/2026 9:30:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 10m
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Itabus11h 10m010:20 AMFlorenceVilla Costanza Bus Station9:30 PMLyonLyon Avenue Tony Garnier Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 10:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/11/2026 9:30:00 PM. 50 Premium Economy ticket for $34 per person are available. Travel duration is 11h 10m
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FlixBus11h 15m012:30 PMFlorenceVilla Costanza Bus Station11:45 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 12:30:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/11/2026 11:45:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 11h 15m
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Itabus11h 50m01:05 AMFlorenceVilla Costanza Bus Station12:55 PMLyonPerrache Bus Stop0Premium EconomyA Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 3/11/2026 1:05:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/11/2026 12:55:00 PM. 50 Premium Economy ticket for $31 per person are available. Travel duration is 11h 50m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Florence to Lyon
What are the most popular stations in Florence and Lyon?
In Florence, you will usually depart from Santa Maria Novella Central Station, Villa Costanza Bus Station or Piazzale Montelungo Bus Stop, while in Lyon you will be arriving at Perrache Bus Stop, Perrache Train Station or Part-Dieu Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Florence? With 5 connections between 3 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Florence and Lyon, you can pay as low as $21 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from ITA Airways: you will get to Lyon in just 5h 40m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Florence and Lyon are Itabus, FlixBus and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Florence and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Scandicci or to Caluire-et-Cuire, and look at flights from Florence Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Florence to Lyon?
The most popular companies between Florence and Lyon, are Itabus, FlixBus and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, FlixBus and BlaBlaCar Bus
Airlines: Vueling Airlines, ITA Airways, Air Dolomiti and 2 more.
All you need to know when you travel from Florence to Lyon
Check all information on comfort and services on all modes of transports from Florence to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Florence to Lyon
How can I reach Lyon from Florence?
Every day, there are on average 5 connections between Flight and Bus, with which you can get to Lyon from Florence.
How far is Lyon from Florence?
The distance between Florence and Lyon is 343.2 miles.
What is the most ecofriendly mode of transport between Florence and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 19 kgs, a car 94 kgs, and a flight 136 kgs.
What is the cheapest mode of transport from Florence to Lyon?
You can get to Lyon with just $21 by taking a Bus from Itabus.
What is the fastest way to get from Florence to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 5h 40m with a Flight from ITA Airways.
More routes to Florence and to Lyon
Looking for more options? Here you can see the most popular routes to Florence and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Florence
- Bari to Florence
- Bergamo Airport to Florence
- Bologna Airport to Florence
- Bologna to Florence
- Caserta to Florence
- Catanzaro to Florence
- Genoa to Florence
- Marseille to Florence
- Messina to Florence
- Milan Malpensa Airport to Florence
- Milan to Florence
- Naples to Florence
- Padua to Florence
- Pisa Airport to Florence
- Pisa to Florence
- Rimini to Florence
- Rome Fiumicino Airport to Florence
- Rome to Florence
- Sala Consilina to Florence
- Salerno to Florence
- Siena to Florence
- Venice to Florence
- Verona to Florence
- Zurich to Florence
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Bordeaux to Lyon
- Clermont-Ferrand to Lyon
- Dusseldorf to Lyon
- Geneva Airport to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Lisbon to Lyon
- London to Lyon
- Marseille to Lyon
- Milan to Lyon
- Mulhouse to Lyon
- Naples to Lyon
- Nice to Lyon
- Paris to Lyon
- Porto to Lyon
- Prague to Lyon
- Rouen to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valence to Lyon
- Valencia to Lyon
- Zurich to Lyon
