What is the best way to travel from Frankfurt am Main to Lyon?
Looking for a trip? Compare all the available Flights, Carpool, Trains and Buses for the journey to Lyon from Frankfurt am Main. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 6 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Frankfurt am Main?
You can get to Lyon with just $52 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/15/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/16/2026 5:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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FlixBus12h 35m08:15 AMFrankfurt am MainCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/15/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/15/2026 8:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 35m
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FlixBus11h 55m011:20 AMFrankfurt am MainCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/15/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/15/2026 11:15:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 11h 55m
Cheapest Buses Saturday
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BlaBlaCar Bus11h 50m08:55 AMFrankfurt am MainCentral Bus Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/16/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 8/16/2026 8:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 50m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/16/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/17/2026 5:10:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 10h 40m
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FlixBus11h 55m011:20 AMFrankfurt am MainCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/16/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/16/2026 11:15:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 11h 55m
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Air Dolomiti1h 20m08:20 AMFrankfurt am Main AirportFrankfurt am Main Airport9:40 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/16/2026 8:20:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/16/2026 9:40:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m08:20 AMFrankfurt am Main AirportFrankfurt am Main Airport9:40 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/16/2026 8:20:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/16/2026 9:40:00 AM. 50 Economy ticket for $295 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m08:20 AMFrankfurt am Main AirportFrankfurt am Main Airport9:40 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/16/2026 8:20:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/16/2026 9:40:00 AM. 50 Economy ticket for $316 per person are available. Travel duration is 1h 20m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus11h 45m01:05 AMFrankfurt am Main AirportFrankfurt am Main Airport12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/17/2026 12:50:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 11h 45m
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FlixBus11h 25m011:05 PMFrankfurt am Main AirportFrankfurt am Main Airport10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 11:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/18/2026 10:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 25m
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FlixBus11h 55m011:20 AMFrankfurt am MainCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/17/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/17/2026 11:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 11h 55m
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Lufthansa1h 20m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport1:45 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 12:25:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/17/2026 1:45:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:50 PMFrankfurt am Main AirportFrankfurt am Main Airport6:10 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 4:50:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/17/2026 6:10:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m08:40 AMFrankfurt am Main AirportFrankfurt am Main Airport10:00 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 8:40:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/17/2026 10:00:00 AM. 50 Economy ticket for $360 per person are available. Travel duration is 1h 20m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus11h 55m011:20 AMFrankfurt am MainCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/18/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/18/2026 11:15:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 55m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/18/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/19/2026 5:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/18/2026 10:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/19/2026 10:30:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 45m
Cheapest Buses Tuesday
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BlaBlaCar Bus11h 50m08:55 AMFrankfurt am MainCentral Bus Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/19/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 8/19/2026 8:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 11h 50m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 10:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 10:30:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 11h 45m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/19/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/20/2026 5:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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TGV Lyria5h 56m02:02 PMFrankfurt am MainCentral Station7:58 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 2:02:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 8/19/2026 7:58:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 5h 56m
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TGV Lyria7h 42m02:02 PMFrankfurt am MainCentral Station9:44 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 2:02:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 8/19/2026 9:44:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 7h 42m
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TGV Lyria7h 57m02:02 PMFrankfurt am MainCentral Station9:59 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 2:02:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 8/19/2026 9:59:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 7h 57m
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/19/2026 4:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/19/2026 6:00:00 PM. 50 Economy ticket for $427 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/19/2026 4:40:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/19/2026 6:00:00 PM. 50 Economy ticket for $461 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/19/2026 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/19/2026 11:20:00 PM. 50 Economy ticket for $471 per person are available. Travel duration is 1h 20m
Cheapest Buses Wednesday
Cheapest Trains Wednesday
Cheapest Flights Wednesday
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FlixBus12h 35m08:15 AMFrankfurt am MainCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/20/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 8:50:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 12h 35m
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FlixBus11h 45m01:05 AMFrankfurt am Main AirportFrankfurt am Main Airport12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/20/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 12:50:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 11h 45m
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FlixBus12h 20m010:55 AMFrankfurt am Main AirportFrankfurt am Main Airport11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/20/2026 10:55:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 11:15:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 12h 20m
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BlaBlaCar7h 0m08:00 AMFrankfurt am Main3:00 PMLyon0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main (Germany) at 8/20/2026 8:00:00 AM to , Lyon (France) arriving at 8/20/2026 3:00:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 0m
Cheapest Buses Thursday
Cheapest Carpool Thursday
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BlaBlaCar Bus11h 50m08:55 AMFrankfurt am MainCentral Bus Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/21/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 8/21/2026 8:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 50m
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FlixBus11h 55m011:20 AMFrankfurt am MainCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/21/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/21/2026 11:15:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 11h 55m
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FlixBus12h 5m012:45 AMFrankfurt am MainCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/21/2026 12:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/21/2026 12:50:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 5m
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BlaBlaCar7h 0m08:00 AMFrankfurt am Main3:00 PMLyon0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main (Germany) at 8/21/2026 8:00:00 AM to , Lyon (France) arriving at 8/21/2026 3:00:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 0m
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Lufthansa1h 20m04:50 PMFrankfurt am Main AirportFrankfurt am Main Airport6:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/21/2026 4:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/21/2026 6:10:00 PM. 50 Economy ticket for $344 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:50 PMFrankfurt am Main AirportFrankfurt am Main Airport6:10 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/21/2026 4:50:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/21/2026 6:10:00 PM. 50 Economy ticket for $359 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:10 PMFrankfurt am Main AirportFrankfurt am Main Airport11:30 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/21/2026 10:10:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/21/2026 11:30:00 PM. 50 Economy ticket for $381 per person are available. Travel duration is 1h 20m
Cheapest Buses Friday
Cheapest Carpool Friday
Cheapest Flights Friday
What are the fastest trips from Frankfurt am Main to Lyon?
You can get to Lyon from Frankfurt am Main in just 1h 20m with a Flight from Air Dolomiti. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/15/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/16/2026 5:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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FlixBus11h 55m011:20 AMFrankfurt am MainCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/15/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/15/2026 11:15:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 11h 55m
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FlixBus12h 35m08:15 AMFrankfurt am MainCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/15/2026 8:15:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/15/2026 8:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 35m
Fastest Buses Saturday
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Air Dolomiti1h 20m08:20 AMFrankfurt am Main AirportFrankfurt am Main Airport9:40 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/16/2026 8:20:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/16/2026 9:40:00 AM. 50 Economy ticket for $292 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m08:20 AMFrankfurt am Main AirportFrankfurt am Main Airport9:40 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/16/2026 8:20:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/16/2026 9:40:00 AM. 50 Economy ticket for $295 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m08:20 AMFrankfurt am Main AirportFrankfurt am Main Airport9:40 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/16/2026 8:20:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/16/2026 9:40:00 AM. 50 Economy ticket for $316 per person are available. Travel duration is 1h 20m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/16/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/17/2026 5:10:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/16/2026 10:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/17/2026 10:30:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 11h 45m
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BlaBlaCar Bus11h 50m08:55 AMFrankfurt am MainCentral Bus Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/16/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 8/16/2026 8:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 50m
Fastest Flights Sunday
Fastest Buses Sunday
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Lufthansa1h 20m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport1:45 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 12:25:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/17/2026 1:45:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:50 PMFrankfurt am Main AirportFrankfurt am Main Airport6:10 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 4:50:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/17/2026 6:10:00 PM. 50 Economy ticket for $310 per person are available. Travel duration is 1h 20m
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Air Dolomiti1h 20m08:40 AMFrankfurt am Main AirportFrankfurt am Main Airport10:00 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 8:40:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/17/2026 10:00:00 AM. 50 Economy ticket for $360 per person are available. Travel duration is 1h 20m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/17/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/18/2026 5:10:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 10h 40m
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FlixBus11h 25m011:05 PMFrankfurt am Main AirportFrankfurt am Main Airport10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 11:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/18/2026 10:30:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 11h 25m
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FlixBus11h 45m01:05 AMFrankfurt am Main AirportFrankfurt am Main Airport12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/17/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/17/2026 12:50:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 11h 45m
Fastest Flights Monday
Fastest Buses Monday
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/18/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/19/2026 5:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/18/2026 10:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/19/2026 10:30:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 11h 45m
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FlixBus11h 55m011:20 AMFrankfurt am MainCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/18/2026 11:20:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/18/2026 11:15:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 55m
Fastest Buses Tuesday
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/19/2026 4:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/19/2026 6:00:00 PM. 50 Economy ticket for $427 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/19/2026 4:40:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/19/2026 6:00:00 PM. 50 Economy ticket for $461 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/19/2026 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/19/2026 11:20:00 PM. 50 Economy ticket for $471 per person are available. Travel duration is 1h 20m
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TGV Lyria5h 56m02:02 PMFrankfurt am MainCentral Station7:58 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 2:02:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 8/19/2026 7:58:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 5h 56m
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TGV Lyria7h 1m012:53 PMFrankfurt am MainCentral Station7:54 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 12:53:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 8/19/2026 7:54:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 7h 1m
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TGV Lyria7h 42m02:02 PMFrankfurt am MainCentral Station9:44 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 2:02:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 8/19/2026 9:44:00 PM. 50 Economy ticket for $122 per person are available. Travel duration is 7h 42m
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FlixBus10h 0m07:05 PMFrankfurt am MainCentral Station5:05 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 7:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 5:05:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 0m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/19/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/20/2026 5:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/19/2026 10:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 10:30:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 11h 45m
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BlaBlaCar7h 0m08:00 AMFrankfurt am Main3:00 PMLyon0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main (Germany) at 8/20/2026 8:00:00 AM to , Lyon (France) arriving at 8/20/2026 3:00:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 0m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/20/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/21/2026 5:10:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 10h 40m
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FlixBus11h 45m01:05 AMFrankfurt am Main AirportFrankfurt am Main Airport12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/20/2026 1:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 12:50:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 11h 45m
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FlixBus12h 20m010:55 AMFrankfurt am Main AirportFrankfurt am Main Airport11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/20/2026 10:55:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/20/2026 11:15:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 12h 20m
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Lufthansa1h 20m04:50 PMFrankfurt am Main AirportFrankfurt am Main Airport6:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/21/2026 4:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 8/21/2026 6:10:00 PM. 50 Economy ticket for $344 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:50 PMFrankfurt am Main AirportFrankfurt am Main Airport6:10 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/21/2026 4:50:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/21/2026 6:10:00 PM. 50 Economy ticket for $359 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:10 PMFrankfurt am Main AirportFrankfurt am Main Airport11:30 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 8/21/2026 10:10:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 8/21/2026 11:30:00 PM. 50 Economy ticket for $381 per person are available. Travel duration is 1h 20m
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BlaBlaCar7h 0m08:00 AMFrankfurt am Main3:00 PMLyon0EconomyA Car from BlaBlaCar goes from , Frankfurt am Main (Germany) at 8/21/2026 8:00:00 AM to , Lyon (France) arriving at 8/21/2026 3:00:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 7h 0m
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FlixBus10h 0m07:05 PMFrankfurt am MainCentral Station5:05 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 8/21/2026 7:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 8/22/2026 5:05:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 10h 0m
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BlaBlaCar Bus10h 40m06:30 PMFrankfurt am MainCentral Bus Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/21/2026 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 8/22/2026 5:10:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus11h 50m08:55 AMFrankfurt am MainCentral Bus Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 8/21/2026 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 8/21/2026 8:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 11h 50m
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Here you will find all operators and timetables for a
Bus from Frankfurt am Main to Lyon
What are the most popular stations in Frankfurt am Main and Lyon?
In Frankfurt am Main, you will usually depart from Central Station, Central Bus Station or West Train Station, while in Lyon you will be arriving at Perrache Train Station, Perrache Bus Stop or Part-Dieu Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Frankfurt am Main? With 8 connections between 6 Flight, Carpool, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Frankfurt am Main and Lyon, you can pay as low as $52 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Dolomiti: you will get to Lyon in just 1h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Frankfurt am Main and Lyon are FlixBus, Lufthansa and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Frankfurt am Main and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Neu-Isenburg or to Caluire-et-Cuire, and look at flights from Frankfurt am Main Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Frankfurt am Main to Lyon?
The most popular companies between Frankfurt am Main and Lyon, are FlixBus, Lufthansa and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Train companies: TGV Lyria
Airlines: Lufthansa and Air Dolomiti
All you need to know when you travel from Frankfurt am Main to Lyon
Check all information on comfort and services on all modes of transports from Frankfurt am Main to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Frankfurt am Main to Lyon
How can I reach Lyon from Frankfurt am Main?
Every day, there are on average 8 connections between Flight, Carpool, Train and Bus, with which you can get to Lyon from Frankfurt am Main.
How far is Lyon from Frankfurt am Main?
The distance between Frankfurt am Main and Lyon is 349.5 miles.
What is the most ecofriendly mode of transport between Frankfurt am Main and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 20 kgs, a car 96 kgs, and a flight 138 kgs.
What is the cheapest mode of transport from Frankfurt am Main to Lyon?
You can get to Lyon with just $52 by taking a Bus from FlixBus.
What is the fastest way to get from Frankfurt am Main to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 20m with a Flight from Air Dolomiti.
More routes to Frankfurt am Main and to Lyon
Looking for more options? Here you can see the most popular routes to Frankfurt am Main and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
