What is the best way to travel from Frankfurt am Main to Lyon?
Looking for a trip? Compare all the available Buses, Trains, Flights and Carpool for the journey to Lyon from Frankfurt am Main. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 6 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Frankfurt am Main?
You can get to Lyon with just $59 by taking a Bus from BlaBlaCar Bus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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BlaBlaCar Bus10h 35m06:30 PMFrankfurt am MainCentral Bus Station5:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/18/2025 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/19/2025 5:05:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 10h 35m
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BlaBlaCar Bus14h 5m012:00 PMFrankfurt am MainCentral Bus Station2:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/18/2025 12:00:00 PM to Perrache Train Station, Lyon (France) arriving at 12/19/2025 2:05:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 14h 5m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/18/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 10:30:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 11h 45m
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Lufthansa1h 20m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport2:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 12:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 2:10:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 11:20:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 4:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 6:00:00 PM. 50 Economy ticket for $413 per person are available. Travel duration is 1h 20m
Cheapest Buses Thursday
Cheapest Flights Thursday
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BlaBlaCar Bus11h 45m08:55 AMFrankfurt am MainCentral Bus Station8:40 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/19/2025 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 12/19/2025 8:40:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 11h 45m
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/19/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 12:50:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 10m
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FlixBus12h 20m08:15 AMFrankfurt am MainCentral Station8:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/19/2025 8:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 8:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 12h 20m
Cheapest Buses Friday
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FlixBus12h 20m08:15 AMFrankfurt am MainCentral Station8:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/20/2025 8:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 8:35:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 12h 20m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/20/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 11h 45m
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FlixBus13h 5m03:30 PMFrankfurt am MainCentral Station4:35 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/20/2025 3:30:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 4:35:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 13h 5m
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Lufthansa1h 20m012:55 PMFrankfurt am Main AirportFrankfurt am Main Airport2:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/20/2025 12:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/20/2025 2:15:00 PM. 50 Economy ticket for $355 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/20/2025 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/20/2025 11:20:00 PM. 50 Economy ticket for $412 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport10:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/20/2025 8:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/20/2025 10:05:00 AM. 50 Economy ticket for $508 per person are available. Travel duration is 1h 20m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Sindbad10h 10m07:35 AMFrankfurt am MainCentral Bus Station5:45 PMLyonPerrache Bus Stop0BasicA Bus from Sindbad goes from Central Bus Station, Frankfurt am Main (Germany) at 12/21/2025 7:35:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 5:45:00 PM. 50 Basic ticket for $70 per person are available. Travel duration is 10h 10m
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BlaBlaCar Bus10h 35m06:30 PMFrankfurt am MainCentral Bus Station5:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/21/2025 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/22/2025 5:05:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 10h 35m
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FlixBus12h 20m08:15 AMFrankfurt am MainCentral Station8:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/21/2025 8:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 8:35:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 12h 20m
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TGV Lyria5h 56m02:02 PMFrankfurt am MainCentral Station7:58 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 12/21/2025 2:02:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/21/2025 7:58:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 5h 56m
Cheapest Buses Sunday
Cheapest Trains Sunday
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/22/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 12:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 10m
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FlixBus13h 5m03:30 PMFrankfurt am MainCentral Station4:35 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/22/2025 3:30:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 4:35:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 13h 5m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/22/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 10:30:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 11h 45m
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Lufthansa1h 20m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport10:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/22/2025 8:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/22/2025 10:05:00 AM. 50 Economy ticket for $308 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/22/2025 1:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/22/2025 2:20:00 PM. 50 Economy ticket for $308 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/22/2025 4:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/22/2025 6:00:00 PM. 50 Economy ticket for $308 per person are available. Travel duration is 1h 20m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/23/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 12:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 10m
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/23/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 4:45:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 9h 40m
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BlaBlaCar Bus10h 35m06:30 PMFrankfurt am MainCentral Bus Station5:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/23/2025 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/24/2025 5:05:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 10h 35m
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Lufthansa1h 20m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport2:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/23/2025 12:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/23/2025 2:10:00 PM. 50 Economy ticket for $287 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:45 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/23/2025 4:45:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport10:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/23/2025 8:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/23/2025 10:05:00 AM. 50 Economy ticket for $356 per person are available. Travel duration is 1h 20m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 4:45:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 9h 40m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 10:30:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 11h 45m
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FlixBus12h 20m08:15 AMFrankfurt am MainCentral Station8:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 8:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 8:35:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 20m
Cheapest Buses Wednesday
What are the fastest trips from Frankfurt am Main to Lyon?
You can get to Lyon from Frankfurt am Main in just 1h 20m with a Flight from Lufthansa. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Lufthansa1h 20m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport2:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 12:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 2:10:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 11:20:00 PM. 50 Economy ticket for $341 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 4:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 6:00:00 PM. 50 Economy ticket for $413 per person are available. Travel duration is 1h 20m
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/18/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 4:45:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 9h 40m
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BlaBlaCar Bus10h 35m06:30 PMFrankfurt am MainCentral Bus Station5:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/18/2025 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/19/2025 5:05:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 10h 35m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/18/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 10:30:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 11h 45m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/19/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 4:45:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 9h 40m
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BlaBlaCar Bus11h 45m08:55 AMFrankfurt am MainCentral Bus Station8:40 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/19/2025 8:55:00 AM to Perrache Train Station, Lyon (France) arriving at 12/19/2025 8:40:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 11h 45m
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/19/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 12:50:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 12h 10m
Fastest Buses Friday
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Lufthansa1h 20m012:55 PMFrankfurt am Main AirportFrankfurt am Main Airport2:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/20/2025 12:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/20/2025 2:15:00 PM. 50 Economy ticket for $355 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport11:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/20/2025 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/20/2025 11:20:00 PM. 50 Economy ticket for $412 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport10:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/20/2025 8:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/20/2025 10:05:00 AM. 50 Economy ticket for $508 per person are available. Travel duration is 1h 20m
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/20/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 4:45:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 9h 40m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/20/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 10:30:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 11h 45m
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/20/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 12:50:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 12h 10m
Fastest Flights Saturday
Fastest Buses Saturday
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TGV Lyria5h 56m02:02 PMFrankfurt am MainCentral Station7:58 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Frankfurt am Main (Germany) at 12/21/2025 2:02:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/21/2025 7:58:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 5h 56m
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/21/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 4:45:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 9h 40m
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Sindbad10h 10m07:35 AMFrankfurt am MainCentral Bus Station5:45 PMLyonPerrache Bus Stop0BasicA Bus from Sindbad goes from Central Bus Station, Frankfurt am Main (Germany) at 12/21/2025 7:35:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 5:45:00 PM. 50 Basic ticket for $70 per person are available. Travel duration is 10h 10m
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BlaBlaCar Bus10h 35m06:30 PMFrankfurt am MainCentral Bus Station5:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/21/2025 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/22/2025 5:05:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 10h 35m
Fastest Trains Sunday
Fastest Buses Sunday
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Lufthansa1h 20m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport10:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/22/2025 8:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/22/2025 10:05:00 AM. 50 Economy ticket for $308 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/22/2025 1:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/22/2025 2:20:00 PM. 50 Economy ticket for $308 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:40 PMFrankfurt am Main AirportFrankfurt am Main Airport6:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/22/2025 4:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/22/2025 6:00:00 PM. 50 Economy ticket for $308 per person are available. Travel duration is 1h 20m
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BlaBlaCar Bus10h 35m06:30 PMFrankfurt am MainCentral Bus Station5:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/22/2025 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/23/2025 5:05:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 10h 35m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/22/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 10:30:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 11h 45m
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/22/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 12:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 10m
Fastest Flights Monday
Fastest Buses Monday
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Lufthansa1h 20m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport2:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/23/2025 12:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/23/2025 2:10:00 PM. 50 Economy ticket for $287 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m04:45 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/23/2025 4:45:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 20m
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Lufthansa1h 20m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport10:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/23/2025 8:45:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/23/2025 10:05:00 AM. 50 Economy ticket for $356 per person are available. Travel duration is 1h 20m
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/23/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 4:45:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 9h 40m
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BlaBlaCar Bus10h 35m06:30 PMFrankfurt am MainCentral Bus Station5:05 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Bus Station, Frankfurt am Main (Germany) at 12/23/2025 6:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/24/2025 5:05:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 10h 35m
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/23/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 12:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 10m
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FlixBus9h 40m07:05 PMFrankfurt am MainCentral Station4:45 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 4:45:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 9h 40m
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FlixBus11h 45m010:45 PMFrankfurt am MainCentral Station10:30 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 10:30:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 11h 45m
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FlixBus12h 10m012:40 AMFrankfurt am MainCentral Station12:50 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 12:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 12:50:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 12h 10m
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Here you will find all operators and timetables for a
Bus from Frankfurt am Main to Lyon
What are the most popular stations in Frankfurt am Main and Lyon?
In Frankfurt am Main, you will usually depart from Central Station, Central Bus Station or West Train Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Frankfurt am Main? With 6 connections between 6 Bus, Train, Flight and Carpool operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Frankfurt am Main and Lyon, you can pay as low as $59 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa: you will get to Lyon in just 1h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Frankfurt am Main and Lyon are FlixBus, Lufthansa and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Frankfurt am Main and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Neu-Isenburg or to Caluire-et-Cuire, and look at flights from Frankfurt am Main Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Frankfurt am Main to Lyon?
The most popular companies between Frankfurt am Main and Lyon, are FlixBus, Lufthansa and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, BlaBlaCar Bus and Sindbad
Train companies: TGV Lyria
Airlines: Lufthansa
All you need to know when you travel from Frankfurt am Main to Lyon
Check all information on comfort and services on all modes of transports from Frankfurt am Main to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Frankfurt am Main to Lyon
How can I reach Lyon from Frankfurt am Main?
Every day, there are on average 6 connections between Bus, Train, Flight and Carpool, with which you can get to Lyon from Frankfurt am Main.
How far is Lyon from Frankfurt am Main?
The distance between Frankfurt am Main and Lyon is 349.5 miles.
What is the most ecofriendly mode of transport between Frankfurt am Main and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 20 kgs, a car 96 kgs, and a flight 138 kgs.
What is the cheapest mode of transport from Frankfurt am Main to Lyon?
You can get to Lyon with just $59 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Frankfurt am Main to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 20m with a Flight from Lufthansa.
More routes to Frankfurt am Main and to Lyon
Looking for more options? Here you can see the most popular routes to Frankfurt am Main and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Frankfurt am Main
- Amsterdam to Frankfurt am Main
- Belgrade to Frankfurt am Main
- Berlin to Frankfurt am Main
- Birmingham to Frankfurt am Main
- Budapest to Frankfurt am Main
- Cologne to Frankfurt am Main
- Dusseldorf to Frankfurt am Main
- Frankfurt Hahn Airport to Frankfurt am Main
- Graz to Frankfurt am Main
- Hamburg to Frankfurt am Main
- Hanover to Frankfurt am Main
- Heidelberg to Frankfurt am Main
- Innsbruck to Frankfurt am Main
- Linz to Frankfurt am Main
- London to Frankfurt am Main
- Munich to Frankfurt am Main
- Paris to Frankfurt am Main
- Priština to Frankfurt am Main
- Simmern (Hunsrück) to Frankfurt am Main
- Stuttgart to Frankfurt am Main
- Trier to Frankfurt am Main
- Vienna to Frankfurt am Main
- Wroclaw to Frankfurt am Main
- Zurich to Frankfurt am Main
- Trips to Lyon
- Alicante to Lyon
- Angers to Lyon
- Annecy to Lyon
- Bordeaux to Lyon
- Bourg-Saint-Maurice (Val d’Isère) to Lyon
- Caen to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- Kehl to Lyon
- Lille to Lyon
- Lisbon to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nice to Lyon
- Perpignan to Lyon
- Rome to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon

