How to get from Greenville, SC to Fort Myers, FL

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What is the best way to travel from Greenville, SC to Fort Myers, FL?

Looking for a trip? Compare all the available Flights and Buses for the journey to Fort Myers, FL from Greenville, SC. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
21h 0m
$99
$102
6
Flight
1h 47m
$119
$198
7

What is the cheapest way to reach Fort Myers, FL from Greenville, SC?

You can get to Fort Myers, FL with just $99 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Tuesday
Wednesday
from $99
Thursday
from $101
Friday
from $183
Saturday
Sunday
from $119
Monday
from $155

    Cheapest Buses Wednesday

  • Greyhound US
    23h 5m
    0
    11:15 AM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    Greyhound US
    Economy
    $99
  • Greyhound US
    21h 55m
    0
    2:45 PM
    Greenville, SC
    Woodruff Rd
    12:40 PM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    Greyhound US
    Economy
    $99
  • FlixBus
    36h 20m
    0
    10:00 PM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    FlixBus
    Economy
    $99

    Cheapest Buses Thursday

  • Greyhound US
    21h 55m
    0
    2:45 PM
    Greenville, SC
    Woodruff Rd
    12:40 PM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    Greyhound US
    Economy
    $101
  • FlixBus
    36h 20m
    0
    10:00 PM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    FlixBus
    Economy
    $103
  • FlixBus
    21h 0m
    0
    1:20 PM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    FlixBus
    Economy
    $110
  • Cheapest Flights Thursday

  • Breeze Airways
    1h 47m
    0
    7:51 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:38 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $142
  • Allegiant Air
    22h 21m
    0
    3:48 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    2:09 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $182
  • Allegiant Air
    23h 36m
    0
    3:17 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    2:53 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $201
  • Breeze Airways
    13h 4m
    0
    8:19 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:23 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $220

    Cheapest Flights Friday

  • Breeze Airways
    13h 10m
    0
    9:20 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    10:30 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $183
  • Allegiant Air
    32h 18m
    0
    3:21 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    11:39 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $214
  • Allegiant Air
    12h 22m
    0
    8:29 AM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    8:51 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $216
  • Allegiant Air
    29h 48m
    0
    3:21 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:09 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $222

    Cheapest Flights Sunday

  • Breeze Airways
    1h 47m
    0
    7:51 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:38 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $119
  • Allegiant Air
    23h 6m
    0
    8:44 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    7:50 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $209
  • Breeze Airways
    13h 4m
    0
    8:19 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:23 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $279
  • Allegiant Air
    17h 56m
    0
    8:44 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    2:40 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $298

    Cheapest Flights Monday

  • Allegiant Air
    47h 10m
    0
    8:29 AM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    7:39 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Allegiant Air
    Economy
    from $155
  • Allegiant Air
    32h 36m
    0
    1:22 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:58 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Allegiant Air
    Economy
    from $158
  • Breeze Airways
    35h 11m
    0
    8:28 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    7:39 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $174
  • Breeze Airways
    14h 0m
    0
    9:20 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    11:20 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $177
  • Breeze Airways
    15h 50m
    0
    9:20 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    1:10 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $224

What are the fastest trips from Greenville, SC to Fort Myers, FL?

You can get to Fort Myers, FL from Greenville, SC in just 1h 47m with a Flight from Breeze Airways. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Tuesday
Wednesday
from 21h 55m
Thursday
from 1h 47m
Friday
from 12h 22m
Saturday
Sunday
from 1h 47m
Monday
from 14h 0m

    Fastest Buses Wednesday

  • Greyhound US
    21h 55m
    0
    2:45 PM
    Greenville, SC
    Woodruff Rd
    12:40 PM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    Greyhound US
    Economy
    $99
  • Greyhound US
    23h 5m
    0
    11:15 AM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    Greyhound US
    Economy
    $99
  • FlixBus
    36h 20m
    0
    10:00 PM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    FlixBus
    Economy
    $99

    Fastest Flights Thursday

  • Breeze Airways
    1h 47m
    0
    7:51 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:38 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $142
  • Breeze Airways
    13h 4m
    0
    8:19 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:23 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $220
  • Allegiant Air
    22h 21m
    0
    3:48 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    2:09 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $182
  • Allegiant Air
    23h 36m
    0
    3:17 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    2:53 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $201
  • Fastest Buses Thursday

  • FlixBus
    21h 0m
    0
    1:20 PM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    FlixBus
    Economy
    $110
  • Greyhound US
    21h 55m
    0
    2:45 PM
    Greenville, SC
    Woodruff Rd
    12:40 PM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    Greyhound US
    Economy
    $101
  • FlixBus
    36h 20m
    0
    10:00 PM
    Greenville, SC
    Woodruff Rd
    10:20 AM
    Fort Myers, FL
    Rosa Parks Transit Center
    0
    FlixBus
    Economy
    $103

    Fastest Flights Friday

  • Allegiant Air
    12h 22m
    0
    8:29 AM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    8:51 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $216
  • Breeze Airways
    13h 10m
    0
    9:20 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    10:30 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $183
  • Allegiant Air
    29h 48m
    0
    3:21 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:09 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $222
  • Allegiant Air
    32h 18m
    0
    3:21 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    11:39 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $214

    Fastest Flights Sunday

  • Breeze Airways
    1h 47m
    0
    7:51 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:38 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $119
  • Breeze Airways
    13h 4m
    0
    8:19 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:23 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $279
  • Allegiant Air
    17h 56m
    0
    8:44 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    2:40 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $298
  • Allegiant Air
    23h 6m
    0
    8:44 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    7:50 PM
    Punta Gorda Airport
    Punta Gorda Airport
    0
    Allegiant Air
    Economy
    from $209

    Fastest Flights Monday

  • Breeze Airways
    14h 0m
    0
    9:20 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    11:20 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $177
  • Breeze Airways
    15h 50m
    0
    9:20 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    1:10 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $224
  • Allegiant Air
    32h 36m
    0
    1:22 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    9:58 PM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Allegiant Air
    Economy
    from $158
  • Breeze Airways
    35h 11m
    0
    8:28 PM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    7:39 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Breeze Airways
    Economy
    from $174
  • Allegiant Air
    47h 10m
    0
    8:29 AM
    Greenville–Spartanburg Airport
    Greenville–Spartanburg Airport
    7:39 AM
    Southwest Florida - Fort Myers Airport
    Southwest Florida - Fort Myers Airport
    0
    Allegiant Air
    Economy
    from $155
Here you will find all operators and timetables for a Bus from Greenville, SC to Fort Myers, FL

What are the most popular stations in Greenville, SC and Fort Myers, FL?

In Greenville, SC, you will usually depart from Woodruff Rd, McDonald's or Greyhound Bus Station, while in Fort Myers, FL you will be arriving at Daniels Pkwy, Rosa Parks Transit Center or Cleveland Ave, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Fort Myers, FL from Greenville, SC? With 5 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Greenville, SC and Fort Myers, FL, you can pay as low as $99 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Breeze Airways: you will get to Fort Myers, FL in just 1h 47m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Greenville, SC and Fort Myers, FL are Allegiant Air, Breeze Airways and Greyhound US, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Greenville, SC and Fort Myers, FL is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Welcome, SC or to Palmona Park, FL, and look at flights from Greenville–Spartanburg Airport, and landing at Punta Gorda Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Greenville, SC to Fort Myers, FL?

The most popular companies between Greenville, SC and Fort Myers, FL, are Allegiant Air, Breeze Airways and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US and FlixBus

Airlines: Allegiant Air and Breeze Airways

All you need to know when you travel from Greenville, SC to Fort Myers, FL

Check all information on comfort and services on all modes of transports from Greenville, SC to Fort Myers, FL. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Greenville, SC to Fort Myers, FL

How can I reach Fort Myers, FL from Greenville, SC?

Every day, there are on average 5 connections between Flight and Bus, with which you can get to Fort Myers, FL from Greenville, SC.

How far is Fort Myers, FL from Greenville, SC?

The distance between Greenville, SC and Fort Myers, FL is 568.4 miles.

What is the most ecofriendly mode of transport between Greenville, SC and Fort Myers, FL?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 156 kgs, and a flight 225 kgs.

What is the cheapest mode of transport from Greenville, SC to Fort Myers, FL?

You can get to Fort Myers, FL with just $99 by taking a Bus from Greyhound US.

What is the fastest way to get from Greenville, SC to Fort Myers, FL?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Fort Myers, FL in just 1h 47m with a Flight from Breeze Airways.

More routes to Greenville, SC and to Fort Myers, FL

Looking for more options? Here you can see the most popular routes to Greenville, SC and to Fort Myers, FL. Simply click on a connection, and you’ll find all the details about the route!

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