Bus from Greenville, SC to Fort Myers, FL from $90

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Compare all timetables for the bus from Greenville, SC to Fort Myers, FL

Here is a selection of the cheapest bus trips from the schedule from Greenville, SC to Fort Myers, FL from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
$143
Sunday
$101
Monday
Tuesday
Wednesday
Thursday

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 0m 1:20 PM Greenville, SC Woodruff Rd 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $143
FlixBus 36h 20m 10:00 PM Greenville, SC Woodruff Rd 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $143
FlixBus 20h 40m 7:40 PM Greenville, SC Woodruff Rd 4:20 PM Fort Myers, FL Rosa Parks Transit Center  Economy $144
Greyhound US 22h 0m 2:45 PM Greenville, SC Woodruff Rd 12:45 PM Fort Myers, FL Rosa Parks Transit Center  Economy $144
  • Did you know that if you travel from Greenville, SC to Fort Myers, FL via Orlando, FL, you can save more than $42? You can find the corresponding connections below.
    • Busbud
      23h 5m
      0
      11:15 AM
      Greenville, SC
      Woodruff Rd
      11:59 PM
      Orlando, FL
      Florida Mall
      0
      Busbud
      Economy
      $71
      • Waiting Time 4h 36m
    • Busbud
      5h 45m
      0
      4:35 AM
      Orlando, FL
      Florida Mall
      10:20 AM
      Fort Myers, FL
      Rosa Parks Transit Center
      0
      Busbud
      Economy
      $30
    Travel time is 2h 25m longer, but you will save $42

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 0m 1:20 PM Greenville, SC Woodruff Rd 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $101
FlixBus 20h 40m 7:40 PM Greenville, SC Woodruff Rd 4:20 PM Fort Myers, FL Rosa Parks Transit Center  Economy $101
FlixBus 36h 20m 10:00 PM Greenville, SC Woodruff Rd 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $103
Greyhound US 22h 0m 2:45 PM Greenville, SC Woodruff Rd 12:45 PM Fort Myers, FL Rosa Parks Transit Center  Economy $104

Best Price Offer: The price for the cheapest bus from Greenville, SC to Fort Myers, FL is $90 on 2/5/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Greenville, SC and Fort Myers, FL

See here how frequent the connections between Greenville, SC and Fort Myers, FL are, during different times and days of the week.
Sunday is the busiest day, with more than 8 daily buses from Greenville, SC to Fort Myers, FL. Saturday has instead the fewest connections, with only 4 daily coaches between Greenville, SC and Fort Myers, FL.
The busiest time of the day is the Afternoon, with 6 buses from Greenville, SC to Fort Myers, FL, while Afternoon sees the fewest connections between Greenville, SC and Fort Myers, FL, with 6 offers.

Facts about the bus from Greenville, SC to Fort Myers, FL

Compare all providers like FlixBus and Greyhound US that travel 6 times every day by bus from Greenville, SC to Fort Myers, FL in one click! Book your bus ticket from Greenville, SC to Fort Myers, FL starting from $90!

Cheapest Bus $90
Fastest Bus 20h 40m
Earliest Bus 1:20 PM
Latest Bus 10:00 PM
Daily Bus Routes 6 Ø
Distance 568.4 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Greenville, SC to Fort Myers, FL

Every day, 6 buses from 2 bus companies leave Greenville, SC for Fort Myers, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/01
Monday 02/02
Tuesday 02/03
Wednesday 02/04
Thursday 02/05
Friday 02/06
Saturday 02/07
$143
Sunday 02/08
$107
Monday 02/09
Tuesday 02/10
Wednesday 02/11
Thursday 02/12
Friday 02/13
Saturday 02/14
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28

The cheapest time to travel from Greenville, SC to Fort Myers, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Greenville, SC to Fort Myers, FL, for the next 30 days.
With a price starting from $101, Sunday is the cheapest day for a bus from Greenville, SC to Fort Myers, FL. Saturday instead is the most expensive day with prices starting from $143.
Afternoon is the cheapest day time for bus tickets from Greenville, SC to Fort Myers, FL, with $101. Afternoon is the most expensive time of the day with prices starting from $101.

How to save money travelling from Greenville, SC to Fort Myers, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Greenville, SC to Fort Myers, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Greenville, SC to Fort Myers, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Greenville, SC to Fort Myers, FL are also emptier.

All bus stations and stops in Greenville, SC and Fort Myers, FL

In the map below, you can see where to find all bus stations in Greenville, SC and Fort Myers, FL.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Greenville, SC to Fort Myers, FL? Compare all modes of transports from Greenville, SC to Fort Myers, FL.

Service and Comfort on the bus from Greenville, SC to Fort Myers, FL

Want to know which seat classes are available on the buses from Greenville, SC to Fort Myers, FL? Or which bus companies serve the route Greenville, SC to Fort Myers, FL? Below you will find answers to your questions.

FAQs about the Greenville, SC to Fort Myers, FL bus

How much does a Greenville, SC Fort Myers, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $90 and takes 21h 0m to reach Fort Myers, FL. Compare offers to save money!

How much could I save by comparing buses from Greenville, SC to Fort Myers, FL?

This route is offered by 2 companies with a range of ticket prices between $90 and $144. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Fort Myers, FL.

On average, how many connections are available from Greenville, SC to Fort Myers, FL each day?

Every day, the Greenville, SC to Fort Myers, FL bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Greenville, SC to Fort Myers, FL take?

The fastest bus from Greenville, SC to Fort Myers, FL is offered by FlixBus and takes 20h 40m. Bus tickets for this connection cost $144. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Greenville, SC to Fort Myers, FL?

The earliest bus arriving in Fort Myers, FL from Greenville, SC starts at 1:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Greenville, SC to Fort Myers, FL?

The latest bus trip departing from Greenville, SC for Fort Myers, FL starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Greenville, SC Fort Myers, FL route?

When traveling by bus from Greenville, SC to Fort Myers, FL, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Greenville, SC and Fort Myers, FL?

You can check all the direct connections between Greenville, SC and Fort Myers, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Greenville, SC to Fort Myers, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Greenville, SC Fort Myers, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Greenville, SC Fort Myers, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Greenville, SC to Fort Myers, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Greenville, SC to Fort Myers, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Greenville, SC and Fort Myers, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Greenville, SC to Fort Myers, FL?

Prices and availability for 6 trips between Greenville, SC and Fort Myers, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Greenville, SC to Fort Myers, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Greenville, SC and to Fort Myers, FL

Here’s an overview of the most popular bus routes to Greenville, SC and to Fort Myers, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Greenville, SC from Charleston, SC Bus to Greenville, SC from Charleston, SC
Bus to Greenville, SC from Port Saint Lucie, FL Bus to Greenville, SC from Port Saint Lucie, FL
Bus to Greenville, SC from Lexington, KY Bus to Greenville, SC from Lexington, KY
Buses to Greenville, SC from San Luis Potosí Buses to Greenville, SC from San Luis Potosí
Palm Coast, FL to Fort Myers, FL bus Palm Coast, FL to Fort Myers, FL bus
Bus from Cambridge, MA to Fort Myers, FL Bus from Cambridge, MA to Fort Myers, FL
Bus Toledo, OH to Fort Myers, FL Bus Toledo, OH to Fort Myers, FL
Bus Dothan, AL to Fort Myers, FL Bus Dothan, AL to Fort Myers, FL
Popular Airport Shuttles to Greenville, SC and to Fort Myers, FL
CheckMyBus › Buses in USA › Bus to Greenville, SC › Bus to Fort Myers, FL

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