Bus Winston-Salem, NC to Greenville, SC: Compare prices and save money

Compare all timetables for the bus from Winston-Salem, NC to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Winston-Salem, NC to Greenville, SC from various bus operators like Greyhound US for the next days.

today

$33

tomorrow

$37

Tuesday

Wednesday

Thursday

$37

Friday

Saturday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	3h 55m	6:55 AM	Winston-Salem, NC	Greyhound Bus Station	10:50 AM	Greenville, SC	Woodruff Rd		Economy	$33	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 11/16/2025 6:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 11/16/2025 10:50:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 3h 55m
	Greyhound US	4h 10m	10:25 AM	Winston-Salem, NC	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$58	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 11/16/2025 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 11/16/2025 2:35:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 4h 10m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	3h 55m	6:55 AM	Winston-Salem, NC	Greyhound Bus Station	10:50 AM	Greenville, SC	Woodruff Rd		Economy	$37	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 11/17/2025 6:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 11/17/2025 10:50:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 3h 55m
	Greyhound US	4h 10m	10:25 AM	Winston-Salem, NC	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$53	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 11/17/2025 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 11/17/2025 2:35:00 PM. 50 Economy ticket for $53 per person are available. Travel duration is 4h 10m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	3h 55m	6:55 AM	Winston-Salem, NC	Greyhound Bus Station	10:50 AM	Greenville, SC	Woodruff Rd		Economy	$37	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 11/20/2025 6:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 11/20/2025 10:50:00 AM. 50 Economy ticket for $37 per person are available. Travel duration is 3h 55m
	Greyhound US	4h 10m	10:25 AM	Winston-Salem, NC	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$51	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 11/20/2025 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 11/20/2025 2:35:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 4h 10m

Best Price Offer: The price for the cheapest bus from Winston-Salem, NC to Greenville, SC is $33 on 11/16/2025. Flexible travelers save on ticket prices.

Facts about the bus from Winston-Salem, NC to Greenville, SC

Compare all providers like Greyhound US that travel 2 times every day by bus from Winston-Salem, NC to Greenville, SC in one click! Book your bus ticket from Winston-Salem, NC to Greenville, SC starting from $33!

Cheapest Bus	$33
Fastest Bus	3h 55m
Earliest Bus	6:55 AM
Latest Bus	10:25 AM
Daily Bus Routes	2 Ø
Distance	148.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Winston-Salem, NC to Greenville, SC

Every day, 2 buses from 1 bus companies leave Winston-Salem, NC for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/16/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/16

$33

Monday 11/17

$37

Tuesday 11/18

Wednesday 11/19

Thursday 11/20

$37

Friday 11/21

Saturday 11/22

Sunday 11/23

Monday 11/24

Tuesday 11/25

Wednesday 11/26

Thursday 11/27

Friday 11/28

Saturday 11/29

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

Sunday 12/07

Monday 12/08

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

Friday 12/12

Saturday 12/13

How to save money travelling from Winston-Salem, NC to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Winston-Salem, NC to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Winston-Salem, NC to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Winston-Salem, NC to Greenville, SC are also emptier.

Beloved bus companies from Winston-Salem, NC to Greenville, SC

These are the most booked bus companies between Winston-Salem, NC to Greenville, SC from our users.

Greyhound US from Winston-Salem, NC to Greenville, SC

Here you will find the key facts about the Greyhound US bus route Winston-Salem, NC to Greenville, SC:

Cheapest Price	$33
Fastest Bus	3h 55m
Earliest Bus	6:55 AM
Last Bus	10:25 AM
Daily Connections	2 Ø
Found on	11/11/2025

All bus stations and stops in Winston-Salem, NC and Greenville, SC

In the map below, you can see where to find all bus stations in Winston-Salem, NC and Greenville, SC.

Greyhound Bus Station

W 5th St 100

Hong Kong King Buffet

Silas Creek Pkwy 1237

Forsyth Hospital

Silas Creek Pkwy 3333

E Sprague St

E Sprague St 841

Hicks St.

McDonald's

Woodruff Rd 1111

Guadalajara Supermarket

White Horse Rd 2803

Greyhound Bus Station

Hendrix Dr 9

N Church St

Woodruff Rd

Woodruff Rd 1116

Service and Comfort on the bus from Winston-Salem, NC to Greenville, SC

Want to know which seat classes are available on the buses from Winston-Salem, NC to Greenville, SC? Or which bus companies serve the route Winston-Salem, NC to Greenville, SC? Below you will find answers to your questions.

FAQs about the Winston-Salem, NC to Greenville, SC bus

How much does a Winston-Salem, NC Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $33 and takes 3h 55m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Winston-Salem, NC to Greenville, SC?

This route is offered by 1 companies with a range of ticket prices between $33 and $58. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Winston-Salem, NC to Greenville, SC each day?

Every day, the Winston-Salem, NC to Greenville, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Winston-Salem, NC to Greenville, SC take?

The fastest bus from Winston-Salem, NC to Greenville, SC is offered by Greyhound US and takes 3h 55m. Bus tickets for this connection cost $33. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Winston-Salem, NC to Greenville, SC?

The earliest bus arriving in Greenville, SC from Winston-Salem, NC starts at 6:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Winston-Salem, NC to Greenville, SC?

The latest bus trip departing from Winston-Salem, NC for Greenville, SC starts at 10:25 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Winston-Salem, NC Greenville, SC route?

When traveling by bus from Winston-Salem, NC to Greenville, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Winston-Salem, NC and Greenville, SC?

You can check all the direct connections between Winston-Salem, NC and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Winston-Salem, NC to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Winston-Salem, NC Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Winston-Salem, NC Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Winston-Salem, NC to Greenville, SC on your planned travel date.

Available seat classes which are offered on the bus route Winston-Salem, NC to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Winston-Salem, NC and to Greenville, SC

Here’s an overview of the most popular bus routes to Winston-Salem, NC and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!