Bus Winston-Salem, NC to Greenville, SC: Compare prices and save money

Compare all timetables for the bus from Winston-Salem, NC to Greenville, SC

Here is a selection of the cheapest bus trips from the schedule from Winston-Salem, NC to Greenville, SC from various bus operators like Greyhound US for the next days.

today

$31

tomorrow

$19

Tuesday

Wednesday

$22

Thursday

Friday

$31

Saturday

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	3h 55m	6:55 AM	Winston-Salem, NC	Greyhound Bus Station	10:50 AM	Greenville, SC	Woodruff Rd		Economy	$31	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/22/2026 6:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/22/2026 10:50:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 3h 55m
	Greyhound US	4h 10m	10:25 AM	Winston-Salem, NC	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$37	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/22/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/22/2026 2:35:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 4h 10m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	3h 55m	6:55 AM	Winston-Salem, NC	Greyhound Bus Station	10:50 AM	Greenville, SC	Woodruff Rd		Economy	$19	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/23/2026 6:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/23/2026 10:50:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 3h 55m
	Greyhound US	4h 10m	10:25 AM	Winston-Salem, NC	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$30	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/23/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/23/2026 2:35:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 4h 10m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	3h 55m	6:55 AM	Winston-Salem, NC	Greyhound Bus Station	10:50 AM	Greenville, SC	Woodruff Rd		Economy	$22	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/25/2026 6:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/25/2026 10:50:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 3h 55m
	Greyhound US	4h 10m	10:25 AM	Winston-Salem, NC	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$35	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/25/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/25/2026 2:35:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 4h 10m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	3h 55m	6:55 AM	Winston-Salem, NC	Greyhound Bus Station	10:50 AM	Greenville, SC	Woodruff Rd		Economy	$31	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/27/2026 6:55:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/27/2026 10:50:00 AM. 50 Economy ticket for $31 per person are available. Travel duration is 3h 55m
	Greyhound US	4h 10m	10:25 AM	Winston-Salem, NC	Greyhound Bus Station	2:35 PM	Greenville, SC	Woodruff Rd		Economy	$43	A Bus from Greyhound US goes from Greyhound Bus Station, Winston-Salem, NC (USA) at 3/27/2026 10:25:00 AM to Woodruff Rd, Greenville, SC (USA) arriving at 3/27/2026 2:35:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 4h 10m

Best Price Offer: The price for the cheapest bus from Winston-Salem, NC to Greenville, SC is $19 on 3/23/2026. Flexible travelers save on ticket prices.

Facts about the bus from Winston-Salem, NC to Greenville, SC

Compare all providers like Greyhound US that travel 2 times every day by bus from Winston-Salem, NC to Greenville, SC in one click! Book your bus ticket from Winston-Salem, NC to Greenville, SC starting from $19!

Cheapest Bus	$19
Fastest Bus	3h 55m
Earliest Bus	6:55 AM
Latest Bus	10:25 AM
Daily Bus Routes	2 Ø
Distance	148.6 miles
Bus Companies	Greyhound US

Cheapest bus connections from Winston-Salem, NC to Greenville, SC

Every day, 2 buses from 1 bus companies leave Winston-Salem, NC for Greenville, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

$31

Monday 03/23

$23

Tuesday 03/24

Wednesday 03/25

$22

Thursday 03/26

Friday 03/27

$31

Saturday 03/28

Sunday 03/29

$33

Monday 03/30

Tuesday 03/31

$27

Wednesday 04/01

$31

Thursday 04/02

Friday 04/03

Saturday 04/04

$27

Sunday 04/05

$31

Monday 04/06

$31

Tuesday 04/07

$25

Wednesday 04/08

$28

Thursday 04/09

$24

Friday 04/10

$31

Saturday 04/11

$116

Sunday 04/12

$31

Monday 04/13

$25

Tuesday 04/14

$24

Wednesday 04/15

$115

Thursday 04/16

$115

Friday 04/17

$116

Saturday 04/18

How to save money travelling from Winston-Salem, NC to Greenville, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Winston-Salem, NC to Greenville, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Winston-Salem, NC to Greenville, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Winston-Salem, NC to Greenville, SC are also emptier.

All bus stations and stops in Winston-Salem, NC and Greenville, SC

In the map below, you can see where to find all bus stations in Winston-Salem, NC and Greenville, SC.

Greyhound Bus Station

W 5th St 100

Forsyth Hospital

Silas Creek Pkwy 3333

Hong Kong King Buffet

Silas Creek Pkwy 1237

E Sprague St

E Sprague St 841

North Carolina Baptist Hospital

Queen St 2034-2020

McDonald's

Woodruff Rd 1111

Woodruff Rd

Woodruff Rd 1116

Greyhound Bus Station

Hendrix Dr 9

N Church St

Guadalajara Supermarket

White Horse Rd 2803

Service and Comfort on the bus from Winston-Salem, NC to Greenville, SC

Want to know which seat classes are available on the buses from Winston-Salem, NC to Greenville, SC? Or which bus companies serve the route Winston-Salem, NC to Greenville, SC? Below you will find answers to your questions.

FAQs about the Winston-Salem, NC to Greenville, SC bus

How much does a Winston-Salem, NC Greenville, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $19 and takes 3h 55m to reach Greenville, SC. Compare offers to save money!

How much could I save by comparing buses from Winston-Salem, NC to Greenville, SC?

This route is offered by 1 companies with a range of ticket prices between $19 and $43. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Greenville, SC.

On average, how many connections are available from Winston-Salem, NC to Greenville, SC each day?

Every day, the Winston-Salem, NC to Greenville, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Winston-Salem, NC to Greenville, SC take?

The fastest bus from Winston-Salem, NC to Greenville, SC is offered by Greyhound US and takes 3h 55m. Bus tickets for this connection cost $31. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Winston-Salem, NC to Greenville, SC?

The earliest bus arriving in Greenville, SC from Winston-Salem, NC starts at 6:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Winston-Salem, NC to Greenville, SC?

The latest bus trip departing from Winston-Salem, NC for Greenville, SC starts at 10:25 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Winston-Salem, NC Greenville, SC route?

When traveling by bus from Winston-Salem, NC to Greenville, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Winston-Salem, NC and Greenville, SC?

You can check all the direct connections between Winston-Salem, NC and Greenville, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Winston-Salem, NC to Greenville, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Winston-Salem, NC Greenville, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Winston-Salem, NC Greenville, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Winston-Salem, NC to Greenville, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Winston-Salem, NC to Greenville, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Winston-Salem, NC and Greenville, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Winston-Salem, NC to Greenville, SC?

Prices and availability for 2 trips between Winston-Salem, NC and Greenville, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Winston-Salem, NC to Greenville, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Winston-Salem, NC and to Greenville, SC

Here’s an overview of the most popular bus routes to Winston-Salem, NC and to Greenville, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!