Bus Indianapolis to Winston-Salem, NC

Compare all timetables for the bus from Indianapolis to Winston-Salem, NC

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to Winston-Salem, NC from various bus operators like FlixBus or Greyhound US for the next days.

today

$82

tomorrow

$86

Saturday

Sunday

Monday

Tuesday

Wednesday

$84

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 25m	7:55 PM	Indianapolis	Central Bus Station	10:20 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$82	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 6/4/2026 7:55:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/5/2026 10:20:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 14h 25m
FlixBus	20h 20m	6:25 PM	Indianapolis	Washington / Delaware	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$82	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 6/4/2026 6:25:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/5/2026 2:45:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 20h 20m
FlixBus	18h 0m	4:20 PM	Indianapolis	Washington / Delaware	10:20 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$83	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 6/4/2026 4:20:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/5/2026 10:20:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 0m
Greyhound US	19h 45m	11:15 AM	Indianapolis	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$87	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 6/4/2026 11:15:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/5/2026 7:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 45m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 25m	7:55 PM	Indianapolis	Central Bus Station	10:20 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$86	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 6/5/2026 7:55:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/6/2026 10:20:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 14h 25m
FlixBus	18h 0m	4:20 PM	Indianapolis	Washington / Delaware	10:20 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$86	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 6/5/2026 4:20:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/6/2026 10:20:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 18h 0m
FlixBus	20h 20m	6:25 PM	Indianapolis	Washington / Delaware	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$86	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 6/5/2026 6:25:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/6/2026 2:45:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 20m
Greyhound US	19h 45m	11:15 AM	Indianapolis	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$88	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 6/5/2026 11:15:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/6/2026 7:00:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 45m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	14h 25m	7:55 PM	Indianapolis	Central Bus Station	10:20 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$84	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 6/10/2026 7:55:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/11/2026 10:20:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 14h 25m
FlixBus	18h 0m	4:20 PM	Indianapolis	Washington / Delaware	10:20 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$84	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 6/10/2026 4:20:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/11/2026 10:20:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 18h 0m
Greyhound US	19h 45m	11:15 AM	Indianapolis	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$86	A Bus from Greyhound US goes from Central Bus Station, Indianapolis (USA) at 6/10/2026 11:15:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/11/2026 7:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 45m
FlixBus	20h 20m	6:25 PM	Indianapolis	Washington / Delaware	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$93	A Bus from FlixBus goes from Washington / Delaware, Indianapolis (USA) at 6/10/2026 6:25:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 6/11/2026 2:45:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 20h 20m

Best Price Offer: The price for the cheapest bus from Indianapolis to Winston-Salem, NC is $82 on 6/4/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Indianapolis and Winston-Salem, NC

See here how frequent the connections between Indianapolis and Winston-Salem, NC are, during different times and days of the week.

Wednesday is the busiest day, with more than 4 daily buses from Indianapolis to Winston-Salem, NC. Wednesday has instead the fewest connections, with only 4 daily coaches between Indianapolis and Winston-Salem, NC.

The busiest time of the day is the Evening, with 6 buses from Indianapolis to Winston-Salem, NC, while Morning sees the fewest connections between Indianapolis and Winston-Salem, NC, with 3 offers.

Facts about the bus from Indianapolis to Winston-Salem, NC

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Indianapolis to Winston-Salem, NC in one click! Book your bus ticket from Indianapolis to Winston-Salem, NC starting from $82!

Cheapest Bus	$82
Fastest Bus	14h 25m
Earliest Bus	11:15 AM
Latest Bus	7:55 PM
Daily Bus Routes	4 Ø
Distance	409.7 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Indianapolis to Winston-Salem, NC

Every day, 4 buses from 2 bus companies leave Indianapolis for Winston-Salem, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/31

Monday 06/01

Tuesday 06/02

Wednesday 06/03

Thursday 06/04

$82

Friday 06/05

$86

Saturday 06/06

Sunday 06/07

Monday 06/08

Tuesday 06/09

Wednesday 06/10

$84

Thursday 06/11

$84

Friday 06/12

Saturday 06/13

$88

Sunday 06/14

$85

Monday 06/15

Tuesday 06/16

$84

Wednesday 06/17

$88

Thursday 06/18

$88

Friday 06/19

$87

Saturday 06/20

Sunday 06/21

$86

Monday 06/22

$87

Tuesday 06/23

$87

Wednesday 06/24

Thursday 06/25

$84

Friday 06/26

Saturday 06/27

The cheapest time to travel from Indianapolis to Winston-Salem, NC

See here on which day and which time of the day you can find the cheapest bus ticket from Indianapolis to Winston-Salem, NC, for the next 30 days.

With a price starting from $82, Thursday is the cheapest day for a bus from Indianapolis to Winston-Salem, NC. Friday instead is the most expensive day with prices starting from $86.

Evening is the cheapest day time for bus tickets from Indianapolis to Winston-Salem, NC, with $82. Morning is the most expensive time of the day with prices starting from $86.

How to save money travelling from Indianapolis to Winston-Salem, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to Winston-Salem, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to Winston-Salem, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to Winston-Salem, NC are also emptier.

Beloved bus companies from Indianapolis to Winston-Salem, NC

These are the most booked bus companies between Indianapolis to Winston-Salem, NC from our users.

Greyhound US from Indianapolis to Winston-Salem, NC

Here you will find the key facts about the Greyhound US bus route Indianapolis to Winston-Salem, NC:

Cheapest Price	$82
Fastest Bus	14h 25m
Earliest Bus	11:15 AM
Last Bus	7:55 PM
Daily Connections	2 Ø
Found on	5/10/2026

All bus stations and stops in Indianapolis and Winston-Salem, NC

In the map below, you can see where to find all bus stations in Indianapolis and Winston-Salem, NC.

Mile Square

Monument Circle 2250

Washington / Delaware

E Washington St between N Delaware St and N Alabama St

Central Bus Station

Greyhound Bus Station

S Illinois St 350

S Keystone Avenue

S Keystone Avenue 3649

Greyhound Bus Station

W 5th St 100

Forsyth Hospital

Silas Creek Pkwy 3333

Hong Kong King Buffet

Silas Creek Pkwy 1237

E Sprague St

E Sprague St 841

North Carolina Baptist Hospital

Queen St 2034-2020

Service and Comfort on the bus from Indianapolis to Winston-Salem, NC

Want to know which seat classes are available on the buses from Indianapolis to Winston-Salem, NC? Or which bus companies serve the route Indianapolis to Winston-Salem, NC? Below you will find answers to your questions.

FAQs about the Indianapolis to Winston-Salem, NC bus

How much does a Indianapolis Winston-Salem, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $82 and takes 20h 20m to reach Winston-Salem, NC. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to Winston-Salem, NC?

This route is offered by 2 companies with a range of ticket prices between $82 and $93. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Winston-Salem, NC.

On average, how many connections are available from Indianapolis to Winston-Salem, NC each day?

Every day, the Indianapolis to Winston-Salem, NC bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to Winston-Salem, NC take?

The fastest bus from Indianapolis to Winston-Salem, NC is offered by Greyhound US and takes 14h 25m. Bus tickets for this connection cost $82. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to Winston-Salem, NC?

The earliest bus arriving in Winston-Salem, NC from Indianapolis starts at 11:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to Winston-Salem, NC?

The latest bus trip departing from Indianapolis for Winston-Salem, NC starts at 7:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis Winston-Salem, NC route?

When traveling by bus from Indianapolis to Winston-Salem, NC, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and Winston-Salem, NC?

You can check all the direct connections between Indianapolis and Winston-Salem, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Indianapolis to Winston-Salem, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis Winston-Salem, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis Winston-Salem, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to Winston-Salem, NC on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to Winston-Salem, NC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Indianapolis and Winston-Salem, NC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to Winston-Salem, NC?

Prices and availability for 4 trips between Indianapolis and Winston-Salem, NC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to Winston-Salem, NC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to Winston-Salem, NC

Here’s an overview of the most popular bus routes to Indianapolis and to Winston-Salem, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!