Bus McAllen, TX to Winston-Salem, NC

Compare all timetables for the bus from McAllen, TX to Winston-Salem, NC

Here is a selection of the cheapest bus trips from the schedule from McAllen, TX to Winston-Salem, NC from various bus operators like Valley Transit, Greyhound US or FlixBus for the next days.

today

$114

tomorrow

$115

Sunday

$107

Monday

$98

Tuesday

$107

Wednesday

$107

Thursday

$110

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$114	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/16/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/17/2026 2:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 31h 10m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$114	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/16/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/18/2026 2:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 38h 45m
Greyhound US	42h 10m	11:35 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$116	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/16/2026 11:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/18/2026 6:45:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 42h 10m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$118	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/16/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/18/2026 7:00:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 38h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$115	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/17/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/18/2026 2:45:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 31h 10m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$116	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/17/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/19/2026 2:45:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 38h 45m
Greyhound US	42h 10m	11:35 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$116	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/17/2026 11:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/19/2026 6:45:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 42h 10m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$128	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/17/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/19/2026 7:00:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 38h 10m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$107	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/18/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/19/2026 2:45:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 31h 10m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$107	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/18/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/20/2026 2:45:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 38h 45m
Greyhound US	42h 10m	11:35 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$110	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/18/2026 11:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/20/2026 6:45:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 42h 10m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$111	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/18/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/20/2026 7:00:00 AM. 50 Economy ticket for $111 per person are available. Travel duration is 38h 10m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 0m	6:35 AM	McAllen, TX	Central Bus Station	2:35 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$98	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/19/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/20/2026 2:35:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 31h 0m
Valley Transit	38h 35m	11:00 PM	McAllen, TX	Central Bus Station	2:35 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$98	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/19/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/21/2026 2:35:00 PM. 50 Economy ticket for $98 per person are available. Travel duration is 38h 35m
Greyhound US	42h 10m	11:35 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$99	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/19/2026 11:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/21/2026 6:45:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 42h 10m
Greyhound US	39h 30m	2:20 PM	McAllen, TX	Central Bus Station	6:50 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$103	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/19/2026 2:20:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/21/2026 6:50:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 39h 30m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 0m	6:35 AM	McAllen, TX	Central Bus Station	2:35 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$107	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/20/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/21/2026 2:35:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 31h 0m
Valley Transit	38h 35m	11:00 PM	McAllen, TX	Central Bus Station	2:35 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$107	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/20/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/22/2026 2:35:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 38h 35m
Greyhound US	42h 10m	11:35 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$109	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/20/2026 11:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/22/2026 6:45:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 42h 10m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 0m	6:35 AM	McAllen, TX	Central Bus Station	2:35 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$107	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/21/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/22/2026 2:35:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 31h 0m
Greyhound US	42h 10m	11:35 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$109	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/21/2026 11:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/23/2026 6:45:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 42h 10m
Valley Transit	38h 35m	11:00 PM	McAllen, TX	Central Bus Station	2:35 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$112	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/21/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/23/2026 2:35:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 38h 35m
Valley Transit	38h 0m	3:50 PM	McAllen, TX	Central Bus Station	6:50 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$125	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/21/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/23/2026 6:50:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 38h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$110	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/22/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/23/2026 2:45:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 31h 10m
Greyhound US	42h 10m	11:35 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$112	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 10/22/2026 11:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/24/2026 6:45:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 42h 10m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$112	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/22/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/24/2026 7:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 38h 10m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$112	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 10/22/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 10/24/2026 2:45:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 38h 45m

Best Price Offer: The price for the cheapest bus from McAllen, TX to Winston-Salem, NC is $98 on 10/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between McAllen, TX and Winston-Salem, NC

See here how frequent the connections between McAllen, TX and Winston-Salem, NC are, during different times and days of the week.

Wednesday is the busiest day, with more than 8 daily buses from McAllen, TX to Winston-Salem, NC. Sunday has instead the fewest connections, with only 4 daily coaches between McAllen, TX and Winston-Salem, NC.

The busiest time of the day is the Morning, with 20 buses from McAllen, TX to Winston-Salem, NC, while Afternoon sees the fewest connections between McAllen, TX and Winston-Salem, NC, with 7 offers.

Facts about the bus from McAllen, TX to Winston-Salem, NC

Compare all providers like Valley Transit, Greyhound US and FlixBus that travel 5 times every day by bus from McAllen, TX to Winston-Salem, NC in one click! Book your bus ticket from McAllen, TX to Winston-Salem, NC starting from $98!

Cheapest Bus	$98
Fastest Bus	32h 0m
Earliest Bus	6:35 AM
Latest Bus	11:00 PM
Daily Bus Routes	5 Ø
Distance	1,261.4 miles
Bus Companies	Valley Transit, Greyhound US, FlixBus and Greyhound Lines Mexico

Cheapest bus connections from McAllen, TX to Winston-Salem, NC

Every day, 5 buses from 4 bus companies leave McAllen, TX for Winston-Salem, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/16/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 10/11

Monday 10/12

Tuesday 10/13

Wednesday 10/14

Thursday 10/15

Friday 10/16

$114

Saturday 10/17

$115

Sunday 10/18

$107

Monday 10/19

$98

Tuesday 10/20

$107

Wednesday 10/21

$111

Thursday 10/22

$110

Friday 10/23

$107

Saturday 10/24

$113

Sunday 10/25

$102

Monday 10/26

$107

Tuesday 10/27

$115

Wednesday 10/28

Thursday 10/29

Friday 10/30

Saturday 10/31

Sunday 11/01

Monday 11/02

Tuesday 11/03

Wednesday 11/04

$118

Thursday 11/05

Friday 11/06

$118

Saturday 11/07

The cheapest time to travel from McAllen, TX to Winston-Salem, NC

See here on which day and which time of the day you can find the cheapest bus ticket from McAllen, TX to Winston-Salem, NC, for the next 30 days.

With a price starting from $98, Monday is the cheapest day for a bus from McAllen, TX to Winston-Salem, NC. Saturday instead is the most expensive day with prices starting from $113.

Evening is the cheapest day time for bus tickets from McAllen, TX to Winston-Salem, NC, with $98. Afternoon is the most expensive time of the day with prices starting from $103.

How to save money travelling from McAllen, TX to Winston-Salem, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from McAllen, TX to Winston-Salem, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from McAllen, TX to Winston-Salem, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from McAllen, TX to Winston-Salem, NC are also emptier.

Beloved bus companies from McAllen, TX to Winston-Salem, NC

These are the most booked bus companies between McAllen, TX to Winston-Salem, NC from our users.

Valley Transit from McAllen, TX to Winston-Salem, NC

Here you will find the key facts about the Valley Transit bus route McAllen, TX to Winston-Salem, NC:

Cheapest Price	$98
Fastest Bus	32h 0m
Earliest Bus	6:35 AM
Last Bus	11:00 PM
Daily Connections	2 Ø
Found on	9/20/2026

All bus stations and stops in McAllen, TX and Winston-Salem, NC

In the map below, you can see where to find all bus stations in McAllen, TX and Winston-Salem, NC.

Central Bus Station

U.S. 83 Business 1501

Frontera México-USA

Greyhound Bus Station

W 5th St 100

Forsyth Hospital

Silas Creek Pkwy 3333

E Sprague St

E Sprague St 841

North Carolina Baptist Hospital

Queen St 2034-2020

Hicks St.

Service and Comfort on the bus from McAllen, TX to Winston-Salem, NC

Want to know which seat classes are available on the buses from McAllen, TX to Winston-Salem, NC? Or which bus companies serve the route McAllen, TX to Winston-Salem, NC? Below you will find answers to your questions.

FAQs about the McAllen, TX to Winston-Salem, NC bus

How much does a McAllen, TX Winston-Salem, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $98 and takes 39h 35m to reach Winston-Salem, NC. Compare offers to save money!

How much could I save by comparing buses from McAllen, TX to Winston-Salem, NC?

This route is offered by 4 companies with a range of ticket prices between $98 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Winston-Salem, NC.

On average, how many connections are available from McAllen, TX to Winston-Salem, NC each day?

Every day, the McAllen, TX to Winston-Salem, NC bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from McAllen, TX to Winston-Salem, NC take?

The fastest bus from McAllen, TX to Winston-Salem, NC is offered by Valley Transit and takes 32h 0m. Bus tickets for this connection cost $98. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from McAllen, TX to Winston-Salem, NC?

The earliest bus arriving in Winston-Salem, NC from McAllen, TX starts at 6:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from McAllen, TX to Winston-Salem, NC?

The latest bus trip departing from McAllen, TX for Winston-Salem, NC starts at 11:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the McAllen, TX Winston-Salem, NC route?

When traveling by bus from McAllen, TX to Winston-Salem, NC, passengers can travel with Valley Transit, Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between McAllen, TX and Winston-Salem, NC?

You can check all the direct connections between McAllen, TX and Winston-Salem, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Valley Transit, Greyhound US and FlixBus.

What can I take with me on the McAllen, TX to Winston-Salem, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the McAllen, TX Winston-Salem, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the McAllen, TX Winston-Salem, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from McAllen, TX to Winston-Salem, NC on your planned travel date.

How does CheckMyBus find the best bus deals from McAllen, TX to Winston-Salem, NC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between McAllen, TX and Winston-Salem, NC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from McAllen, TX to Winston-Salem, NC?

Prices and availability for 5 trips between McAllen, TX and Winston-Salem, NC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route McAllen, TX to Winston-Salem, NC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to McAllen, TX and to Winston-Salem, NC

Here’s an overview of the most popular bus routes to McAllen, TX and to Winston-Salem, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!