Bus McAllen, TX to Winston-Salem, NC

Compare all timetables for the bus from McAllen, TX to Winston-Salem, NC

Here is a selection of the cheapest bus trips from the schedule from McAllen, TX to Winston-Salem, NC from various bus operators like Valley Transit, Greyhound Lines Mexico or FlixBus for the next days.

today

$131

tomorrow

Friday

$117

Saturday

$124

Sunday

$113

Monday

$125

Tuesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$131	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/15/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/17/2026 6:45:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 42h 25m
FlixBus	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$132	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 7/15/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/16/2026 2:45:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 31h 10m
FlixBus	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$145	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 7/15/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/17/2026 7:00:00 AM. 50 Economy ticket for $145 per person are available. Travel duration is 38h 10m
FlixBus	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$150	A Bus from FlixBus goes from Central Bus Station, McAllen, TX (USA) at 7/15/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/17/2026 2:45:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 38h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$117	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/17/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/19/2026 2:45:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 38h 45m
Greyhound US	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$119	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/17/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/19/2026 6:45:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 42h 25m
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$126	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/17/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/18/2026 2:45:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 31h 10m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$128	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/17/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/19/2026 7:00:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 38h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Valley Transit	31h 10m	6:35 AM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$124	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/18/2026 6:35:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/19/2026 2:45:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 31h 10m
Greyhound US	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$125	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/18/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/20/2026 6:45:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 42h 25m
Valley Transit	38h 10m	3:50 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station	Economy	$128	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/18/2026 3:50:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/20/2026 7:00:00 AM. 50 Economy ticket for $128 per person are available. Travel duration is 38h 10m
Valley Transit	38h 45m	11:00 PM	McAllen, TX	Central Bus Station	2:45 PM	Winston-Salem, NC	Greyhound Bus Station	Economy	$136	A Bus from Valley Transit goes from Central Bus Station, McAllen, TX (USA) at 7/18/2026 11:00:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/20/2026 2:45:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 38h 45m

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound Lines Mexico	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station		Economy	$113	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/19/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/21/2026 6:45:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 42h 25m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound Lines Mexico	42h 25m	11:20 AM	McAllen, TX	Central Bus Station	6:45 AM	Winston-Salem, NC	Greyhound Bus Station		Economy	$125	A Bus from Greyhound Lines Mexico goes from Central Bus Station, McAllen, TX (USA) at 7/20/2026 11:20:00 AM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/22/2026 6:45:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 42h 25m
	Greyhound US	39h 40m	2:20 PM	McAllen, TX	Central Bus Station	7:00 AM	Winston-Salem, NC	Greyhound Bus Station		Economy	$130	A Bus from Greyhound US goes from Central Bus Station, McAllen, TX (USA) at 7/20/2026 2:20:00 PM to Greyhound Bus Station, Winston-Salem, NC (USA) arriving at 7/22/2026 7:00:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 39h 40m

Best Price Offer: The price for the cheapest bus from McAllen, TX to Winston-Salem, NC is $111 on 7/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between McAllen, TX and Winston-Salem, NC

See here how frequent the connections between McAllen, TX and Winston-Salem, NC are, during different times and days of the week.

Friday is the busiest day, with more than 5 daily buses from McAllen, TX to Winston-Salem, NC. Sunday has instead the fewest connections, with only 1 daily coaches between McAllen, TX and Winston-Salem, NC.

The busiest time of the day is the Morning, with 9 buses from McAllen, TX to Winston-Salem, NC, while Evening sees the fewest connections between McAllen, TX and Winston-Salem, NC, with 3 offers.

Facts about the bus from McAllen, TX to Winston-Salem, NC

Compare all providers like Valley Transit, Greyhound Lines Mexico and FlixBus that travel 3 times every day by bus from McAllen, TX to Winston-Salem, NC in one click! Book your bus ticket from McAllen, TX to Winston-Salem, NC starting from $111!

Cheapest Bus	$111
Fastest Bus	32h 10m
Earliest Bus	6:35 AM
Latest Bus	2:20 PM
Daily Bus Routes	3 Ø
Distance	1,261.4 miles
Bus Companies	Valley Transit, Greyhound Lines Mexico, FlixBus and Greyhound US

Cheapest bus connections from McAllen, TX to Winston-Salem, NC

Every day, 3 buses from 4 bus companies leave McAllen, TX for Winston-Salem, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/15/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/12

Monday 07/13

Tuesday 07/14

Wednesday 07/15

$131

Thursday 07/16

Friday 07/17

$121

Saturday 07/18

$124

Sunday 07/19

$111

Monday 07/20

$122

Tuesday 07/21

Wednesday 07/22

$130

Thursday 07/23

$122

Friday 07/24

$120

Saturday 07/25

$124

Sunday 07/26

$122

Monday 07/27

$124

Tuesday 07/28

$126

Wednesday 07/29

Thursday 07/30

$130

Friday 07/31

Saturday 08/01

$135

Sunday 08/02

Monday 08/03

$116

Tuesday 08/04

$120

Wednesday 08/05

$119

Thursday 08/06

$118

Friday 08/07

$114

Saturday 08/08

The cheapest time to travel from McAllen, TX to Winston-Salem, NC

See here on which day and which time of the day you can find the cheapest bus ticket from McAllen, TX to Winston-Salem, NC, for the next 30 days.

With a price starting from $111, Sunday is the cheapest day for a bus from McAllen, TX to Winston-Salem, NC. Saturday instead is the most expensive day with prices starting from $124.

Morning is the cheapest day time for bus tickets from McAllen, TX to Winston-Salem, NC, with $113. Afternoon is the most expensive time of the day with prices starting from $128.

How to save money travelling from McAllen, TX to Winston-Salem, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from McAllen, TX to Winston-Salem, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from McAllen, TX to Winston-Salem, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from McAllen, TX to Winston-Salem, NC are also emptier.

All bus stations and stops in McAllen, TX and Winston-Salem, NC

In the map below, you can see where to find all bus stations in McAllen, TX and Winston-Salem, NC.

Central Bus Station

U.S. 83 Business 1501

Frontera México-USA

Forsyth Hospital

Silas Creek Pkwy 3333

Hong Kong King Buffet

Silas Creek Pkwy 1237

E Sprague St

E Sprague St 841

North Carolina Baptist Hospital

Queen St 2034-2020

Hicks St.

Service and Comfort on the bus from McAllen, TX to Winston-Salem, NC

Want to know which seat classes are available on the buses from McAllen, TX to Winston-Salem, NC? Or which bus companies serve the route McAllen, TX to Winston-Salem, NC? Below you will find answers to your questions.

FAQs about the McAllen, TX to Winston-Salem, NC bus

How much does a McAllen, TX Winston-Salem, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $111 and takes 43h 25m to reach Winston-Salem, NC. Compare offers to save money!

How much could I save by comparing buses from McAllen, TX to Winston-Salem, NC?

This route is offered by 4 companies with a range of ticket prices between $111 and $150. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Winston-Salem, NC.

On average, how many connections are available from McAllen, TX to Winston-Salem, NC each day?

Every day, the McAllen, TX to Winston-Salem, NC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from McAllen, TX to Winston-Salem, NC take?

The fastest bus from McAllen, TX to Winston-Salem, NC is offered by FlixBus and takes 32h 10m. Bus tickets for this connection cost $132. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from McAllen, TX to Winston-Salem, NC?

The earliest bus arriving in Winston-Salem, NC from McAllen, TX starts at 6:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from McAllen, TX to Winston-Salem, NC?

The latest bus trip departing from McAllen, TX for Winston-Salem, NC starts at 2:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the McAllen, TX Winston-Salem, NC route?

When traveling by bus from McAllen, TX to Winston-Salem, NC, passengers can travel with Valley Transit, Greyhound Lines Mexico and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between McAllen, TX and Winston-Salem, NC?

You can check all the direct connections between McAllen, TX and Winston-Salem, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Valley Transit, Greyhound Lines Mexico and FlixBus.

What can I take with me on the McAllen, TX to Winston-Salem, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the McAllen, TX Winston-Salem, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the McAllen, TX Winston-Salem, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from McAllen, TX to Winston-Salem, NC on your planned travel date.

How does CheckMyBus find the best bus deals from McAllen, TX to Winston-Salem, NC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between McAllen, TX and Winston-Salem, NC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from McAllen, TX to Winston-Salem, NC?

Prices and availability for 3 trips between McAllen, TX and Winston-Salem, NC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route McAllen, TX to Winston-Salem, NC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to McAllen, TX and to Winston-Salem, NC

Here’s an overview of the most popular bus routes to McAllen, TX and to Winston-Salem, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!