Bus from San Antonio, TX to Winston-Salem, NC from $126

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Compare all timetables for the bus from San Antonio, TX to Winston-Salem, NC

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Winston-Salem, NC from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today
from $155
tomorrow
Friday
from $149
Saturday
from $143
Sunday
from $149
Monday
Tuesday
from $126

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    31h 10m
    0
    7:35 AM
    San Antonio, TX
    Bus Station
    2:45 PM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $155
  • FlixBus
    47h 15m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $162
  • FlixBus
    34h 0m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $171

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    28h 45m
    0
    10:00 AM
    San Antonio, TX
    Bus Station
    2:45 PM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $149
  • FlixBus
    34h 0m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $157
  • FlixBus
    47h 15m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $157
  • Greyhound US
    29h 55m
    0
    1:05 AM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $169

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    28h 45m
    0
    10:00 AM
    San Antonio, TX
    Bus Station
    2:45 PM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $143
  • Greyhound US
    29h 55m
    0
    1:05 AM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $167
  • FlixBus
    47h 15m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $180
  • FlixBus
    34h 0m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $181

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    28h 45m
    0
    10:00 AM
    San Antonio, TX
    Bus Station
    2:45 PM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $149
  • FlixBus
    34h 0m
    0
    9:00 PM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $187
  • FlixBus
    47h 15m
    0
    7:45 AM
    San Antonio, TX
    Pearl District
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $187
  • Greyhound US
    29h 55m
    0
    1:05 AM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $214

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    31h 10m
    0
    7:35 AM
    San Antonio, TX
    Bus Station
    2:45 PM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $126
  • Greyhound Lines Mexico
    35h 45m
    0
    7:15 PM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    Greyhound Lines Mexico
    Economy
    $126
  • Greyhound US
    29h 55m
    0
    1:05 AM
    San Antonio, TX
    Bus Station
    7:00 AM
    Winston-Salem, NC
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $131

Frequency of bus connections between San Antonio, TX and Winston-Salem, NC

See here how frequent the connections between San Antonio, TX and Winston-Salem, NC are, during different times and days of the week.
Sunday is the busiest day, with more than 4 daily buses from San Antonio, TX to Winston-Salem, NC. Tuesday has instead the fewest connections, with only 3 daily coaches between San Antonio, TX and Winston-Salem, NC.
The busiest time of the day is the Morning, with 9 buses from San Antonio, TX to Winston-Salem, NC, while Night sees the fewest connections between San Antonio, TX and Winston-Salem, NC, with 4 offers.

Facts about the bus from San Antonio, TX to Winston-Salem, NC

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 3 times every day by bus from San Antonio, TX to Winston-Salem, NC in one click! Book your bus ticket from San Antonio, TX to Winston-Salem, NC starting from $126!

Cheapest Bus $126
Fastest Bus 28h 45m
Earliest Bus 7:35 AM
Latest Bus 7:15 PM
Daily Bus Routes 3 Ø
Distance 1,153.7 miles
Bus Companies FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from San Antonio, TX to Winston-Salem, NC

Every day, 3 buses from 3 bus companies leave San Antonio, TX for Winston-Salem, NC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/09/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
$155
Thursday 07/10
Friday 07/11
$149
Saturday 07/12
$143
Sunday 07/13
$149
Monday 07/14
Tuesday 07/15
$126
Wednesday 07/16
$137
Thursday 07/17
Friday 07/18
Saturday 07/19
Sunday 07/20
Monday 07/21
Tuesday 07/22
Wednesday 07/23
Thursday 07/24
Friday 07/25
Saturday 07/26
Sunday 07/27
Monday 07/28
Tuesday 07/29
Wednesday 07/30
Thursday 07/31
Friday 08/01
Saturday 08/02

The cheapest time to travel from San Antonio, TX to Winston-Salem, NC

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Winston-Salem, NC, for the next 30 days.
With a price starting from $126, Tuesday is the cheapest day for a bus from San Antonio, TX to Winston-Salem, NC. Wednesday instead is the most expensive day with prices starting from $155.
Morning is the cheapest day time for bus tickets from San Antonio, TX to Winston-Salem, NC, with $126. Night is the most expensive time of the day with prices starting from $131.

How to save money travelling from San Antonio, TX to Winston-Salem, NC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Winston-Salem, NC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Winston-Salem, NC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Winston-Salem, NC are also emptier.

Beloved bus companies from San Antonio, TX to Winston-Salem, NC

These are the most booked bus companies between San Antonio, TX to Winston-Salem, NC from our users.

Greyhound Lines Mexico from San Antonio, TX to Winston-Salem, NC

Greyhound Lines Mexico

Here you will find the key facts about the Greyhound Lines Mexico bus route San Antonio, TX to Winston-Salem, NC:

Cheapest Price $126
Fastest Bus 35h 45m
Earliest Bus 7:15 PM
Last Bus 7:15 PM
Daily Connections 1 Ø
Found on 7/6/2025

All bus stations and stops in San Antonio, TX and Winston-Salem, NC

In the map below, you can see where to find all bus stations in San Antonio, TX and Winston-Salem, NC.

Service and Comfort on the bus from San Antonio, TX to Winston-Salem, NC

Want to know which seat classes are available on the buses from San Antonio, TX to Winston-Salem, NC? Or which bus companies serve the route San Antonio, TX to Winston-Salem, NC? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Winston-Salem, NC bus

How much does a San Antonio, TX Winston-Salem, NC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $126 and takes 31h 10m to reach Winston-Salem, NC. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Winston-Salem, NC?

This route is offered by 3 companies with a range of ticket prices between $126 and $214. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Winston-Salem, NC.

On average, how many connections are available from San Antonio, TX to Winston-Salem, NC each day?

Every day, the San Antonio, TX to Winston-Salem, NC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Winston-Salem, NC take?

The fastest bus from San Antonio, TX to Winston-Salem, NC is offered by FlixBus and takes 28h 45m. Bus tickets for this connection cost $149. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Winston-Salem, NC?

The earliest bus arriving in Winston-Salem, NC from San Antonio, TX starts at 7:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Winston-Salem, NC?

The latest bus trip departing from San Antonio, TX for Winston-Salem, NC starts at 7:15 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Winston-Salem, NC route?

When traveling by bus from San Antonio, TX to Winston-Salem, NC, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Winston-Salem, NC?

You can check all the direct connections between San Antonio, TX and Winston-Salem, NC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the San Antonio, TX to Winston-Salem, NC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Winston-Salem, NC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Winston-Salem, NC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Winston-Salem, NC on your planned travel date.

Available seat classes which are offered on the bus route San Antonio, TX to Winston-Salem, NC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Winston-Salem, NC

Here’s an overview of the most popular bus routes to San Antonio, TX and to Winston-Salem, NC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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