Bus from Lake City, FL to Fort Myers, FL from $107

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Compare all timetables for the bus from Lake City, FL to Fort Myers, FL

Here is a selection of the cheapest bus trips from the schedule from Lake City, FL to Fort Myers, FL from various bus operators like Greyhound US for the next days.

today
tomorrow
Wednesday
$179
Thursday
$140
Friday
Saturday
$107
Sunday
$140

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 50m 7:30 PM Lake City, FL Bus Stop 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $179
  • Did you know that if you travel from Lake City, FL to Fort Myers, FL via Orlando, FL, you can save more than $96? You can find the corresponding connections below.
    • Greyhound US
      14h 50m
      0
      7:30 PM
      Lake City, FL
      Bus Stop
      12:55 AM
      Orlando, FL
      Bus Station
      0
      Greyhound US
      Economy
      $53
      • Waiting Time 3h 40m
    • FlixBus
      5h 45m
      0
      4:35 AM
      Orlando, FL
      Florida Mall
      10:20 AM
      Fort Myers, FL
      Rosa Parks Transit Center
      0
      FlixBus
      Economy
      $30
    Travel time is the same as the direct connection, but you will save $96

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 50m 7:30 PM Lake City, FL Bus Stop 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $140
  • Did you know that if you travel from Lake City, FL to Fort Myers, FL via Orlando, FL, you can save more than $73? You can find the corresponding connections below.
    • Greyhound US
      14h 50m
      0
      7:30 PM
      Lake City, FL
      Bus Stop
      11:59 PM
      Orlando, FL
      Bus Station
      0
      Greyhound US
      Economy
      $37
      • Waiting Time 4h 36m
    • FlixBus
      5h 45m
      0
      4:35 AM
      Orlando, FL
      Florida Mall
      10:20 AM
      Fort Myers, FL
      Rosa Parks Transit Center
      0
      FlixBus
      Economy
      $30
    Travel time is the same as the direct connection, but you will save $73

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 50m 7:30 PM Lake City, FL Bus Stop 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $107
  • Did you know that if you travel from Lake City, FL to Fort Myers, FL via Orlando, FL, you can save more than $40? You can find the corresponding connections below.
    • Greyhound US
      14h 50m
      0
      7:30 PM
      Lake City, FL
      Bus Stop
      11:59 PM
      Orlando, FL
      Bus Station
      0
      Greyhound US
      Economy
      $37
      • Waiting Time 4h 36m
    • FlixBus
      5h 45m
      0
      4:35 AM
      Orlando, FL
      Florida Mall
      10:20 AM
      Fort Myers, FL
      Rosa Parks Transit Center
      0
      FlixBus
      Economy
      $30
    Travel time is the same as the direct connection, but you will save $40

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 50m 7:30 PM Lake City, FL Bus Stop 10:20 AM Fort Myers, FL Rosa Parks Transit Center  Economy $140
  • Did you know that if you travel from Lake City, FL to Fort Myers, FL via Orlando, FL, you can save more than $73? You can find the corresponding connections below.
    • Greyhound US
      14h 50m
      0
      7:30 PM
      Lake City, FL
      Bus Stop
      11:59 PM
      Orlando, FL
      Bus Station
      0
      Greyhound US
      Economy
      $37
      • Waiting Time 4h 36m
    • FlixBus
      5h 45m
      0
      4:35 AM
      Orlando, FL
      Florida Mall
      10:20 AM
      Fort Myers, FL
      Rosa Parks Transit Center
      0
      FlixBus
      Economy
      $30
    Travel time is the same as the direct connection, but you will save $73

Best Price Offer: The price for the cheapest bus from Lake City, FL to Fort Myers, FL is $107 on 5/2/2026. Flexible travelers save on ticket prices.


Facts about the bus from Lake City, FL to Fort Myers, FL

Compare all providers like Greyhound US that travel 1 times every day by bus from Lake City, FL to Fort Myers, FL in one click! Book your bus ticket from Lake City, FL to Fort Myers, FL starting from $107!

Cheapest Bus $107
Fastest Bus 14h 50m
Earliest Bus 7:30 PM
Latest Bus 7:30 PM
Daily Bus Routes 1 Ø
Distance 249.7 miles
Bus Companies Greyhound US

Cheapest bus connections from Lake City, FL to Fort Myers, FL

Every day, 1 buses from 1 bus companies leave Lake City, FL for Fort Myers, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/26
Monday 04/27
Tuesday 04/28
Wednesday 04/29
$179
Thursday 04/30
$140
Friday 05/01
Saturday 05/02
$107
Sunday 05/03
$140
Monday 05/04
$121
Tuesday 05/05
Wednesday 05/06
Thursday 05/07
Friday 05/08
Saturday 05/09
Sunday 05/10
Monday 05/11
$167
Tuesday 05/12
Wednesday 05/13
Thursday 05/14
$157
Friday 05/15
$157
Saturday 05/16
$125
Sunday 05/17
$146
Monday 05/18
$161
Tuesday 05/19
$167
Wednesday 05/20
$176
Thursday 05/21
$190
Friday 05/22
$181
Saturday 05/23

How to save money travelling from Lake City, FL to Fort Myers, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lake City, FL to Fort Myers, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lake City, FL to Fort Myers, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lake City, FL to Fort Myers, FL are also emptier.

All bus stations and stops in Lake City, FL and Fort Myers, FL

In the map below, you can see where to find all bus stations in Lake City, FL and Fort Myers, FL.

Service and Comfort on the bus from Lake City, FL to Fort Myers, FL

Want to know which seat classes are available on the buses from Lake City, FL to Fort Myers, FL? Or which bus companies serve the route Lake City, FL to Fort Myers, FL? Below you will find answers to your questions.

FAQs about the Lake City, FL to Fort Myers, FL bus

How much does a Lake City, FL Fort Myers, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $107 and takes 14h 50m to reach Fort Myers, FL. Compare offers to save money!

How much could I save by comparing buses from Lake City, FL to Fort Myers, FL?

This route is offered by 1 companies with a range of ticket prices between $107 and $179. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Fort Myers, FL.

On average, how many connections are available from Lake City, FL to Fort Myers, FL each day?

Every day, the Lake City, FL to Fort Myers, FL bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lake City, FL to Fort Myers, FL take?

The fastest bus from Lake City, FL to Fort Myers, FL is offered by Greyhound US and takes 14h 50m. Bus tickets for this connection cost $179. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lake City, FL to Fort Myers, FL?

The earliest bus arriving in Fort Myers, FL from Lake City, FL starts at 7:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lake City, FL to Fort Myers, FL?

The latest bus trip departing from Lake City, FL for Fort Myers, FL starts at 7:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lake City, FL Fort Myers, FL route?

When traveling by bus from Lake City, FL to Fort Myers, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lake City, FL and Fort Myers, FL?

You can check all the direct connections between Lake City, FL and Fort Myers, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Lake City, FL to Fort Myers, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lake City, FL Fort Myers, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lake City, FL Fort Myers, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lake City, FL to Fort Myers, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Lake City, FL to Fort Myers, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Lake City, FL and Fort Myers, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lake City, FL to Fort Myers, FL?

Prices and availability for 1 trips between Lake City, FL and Fort Myers, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lake City, FL to Fort Myers, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lake City, FL and to Fort Myers, FL

Here’s an overview of the most popular bus routes to Lake City, FL and to Fort Myers, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses to Lake City, FL from Vero Beach, FL Buses to Lake City, FL from Vero Beach, FL
Buses to Lake City, FL from Fort Pierce, FL Buses to Lake City, FL from Fort Pierce, FL
Buses from Joplin, MO to Lake City, FL Buses from Joplin, MO to Lake City, FL
From Tuscaloosa, AL to Lake City, FL bus From Tuscaloosa, AL to Lake City, FL bus
Buses from Bethlehem, PA to Fort Myers, FL Buses from Bethlehem, PA to Fort Myers, FL
From Palm Coast, FL to Fort Myers, FL bus From Palm Coast, FL to Fort Myers, FL bus
Buses from Cambridge, MA to Fort Myers, FL Buses from Cambridge, MA to Fort Myers, FL
Bus to Fort Myers, FL from Mobile, AL Bus to Fort Myers, FL from Mobile, AL
Popular Airport Shuttles to Lake City, FL and to Fort Myers, FL
CheckMyBus › Buses in USA › Bus to Lake City, FL › Bus to Fort Myers, FL

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