Bus Tuscaloosa, AL to Lake City, FL: Compare prices and save money

Compare all timetables for the bus from Tuscaloosa, AL to Lake City, FL

Here is a selection of the cheapest bus trips from the schedule from Tuscaloosa, AL to Lake City, FL from various bus operators like Greyhound US for the next days.

today

$112

tomorrow

$92

Sunday

Monday

Tuesday

Wednesday

$116

Thursday

$95

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	15h 40m	8:50 PM	Tuscaloosa, AL	Greyhound Bus Station	1:30 PM	Lake City, FL	Bus Stop		Economy	$112	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/13/2026 8:50:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/14/2026 1:30:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 15h 40m
	Greyhound US	14h 30m	5:40 PM	Tuscaloosa, AL	Greyhound Bus Station	9:10 AM	Lake City, FL	Bus Stop		Economy	$113	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/13/2026 5:40:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/14/2026 9:10:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 14h 30m

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	14h 30m	5:40 PM	Tuscaloosa, AL	Greyhound Bus Station	9:10 AM	Lake City, FL	Bus Stop		Economy	$92	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/14/2026 5:40:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/15/2026 9:10:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 14h 30m
	Greyhound US	15h 40m	8:50 PM	Tuscaloosa, AL	Greyhound Bus Station	1:30 PM	Lake City, FL	Bus Stop		Economy	$92	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/14/2026 8:50:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/15/2026 1:30:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 40m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	14h 30m	5:40 PM	Tuscaloosa, AL	Greyhound Bus Station	9:10 AM	Lake City, FL	Bus Stop		Economy	$116	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/18/2026 5:40:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/19/2026 9:10:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 14h 30m
	Greyhound US	15h 40m	8:50 PM	Tuscaloosa, AL	Greyhound Bus Station	1:30 PM	Lake City, FL	Bus Stop		Economy	$117	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/18/2026 8:50:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/19/2026 1:30:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 15h 40m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	15h 40m	8:50 PM	Tuscaloosa, AL	Greyhound Bus Station	1:30 PM	Lake City, FL	Bus Stop		Economy	$95	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/19/2026 8:50:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/20/2026 1:30:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 15h 40m
	Greyhound US	14h 30m	5:40 PM	Tuscaloosa, AL	Greyhound Bus Station	9:10 AM	Lake City, FL	Bus Stop		Economy	$96	A Bus from Greyhound US goes from Greyhound Bus Station, Tuscaloosa, AL (USA) at 2/19/2026 5:40:00 PM to Bus Stop, Lake City, FL (USA) arriving at 2/20/2026 9:10:00 AM. 50 Economy ticket for $96 per person are available. Travel duration is 14h 30m

Best Price Offer: The price for the cheapest bus from Tuscaloosa, AL to Lake City, FL is $92 on 2/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Tuscaloosa, AL and Lake City, FL

See here how frequent the connections between Tuscaloosa, AL and Lake City, FL are, during different times and days of the week.

Wednesday is the busiest day, with more than 2 daily buses from Tuscaloosa, AL to Lake City, FL. Wednesday has instead the fewest connections, with only 2 daily coaches between Tuscaloosa, AL and Lake City, FL.

The busiest time of the day is the Afternoon, with 4 buses from Tuscaloosa, AL to Lake City, FL, while Afternoon sees the fewest connections between Tuscaloosa, AL and Lake City, FL, with 4 offers.

Facts about the bus from Tuscaloosa, AL to Lake City, FL

Compare all providers like Greyhound US that travel 2 times every day by bus from Tuscaloosa, AL to Lake City, FL in one click! Book your bus ticket from Tuscaloosa, AL to Lake City, FL starting from $92!

Cheapest Bus	$92
Fastest Bus	15h 30m
Earliest Bus	5:40 PM
Latest Bus	8:50 PM
Daily Bus Routes	2 Ø
Distance	356.1 miles
Bus Companies	Greyhound US

Cheapest bus connections from Tuscaloosa, AL to Lake City, FL

Every day, 2 buses from 1 bus companies leave Tuscaloosa, AL for Lake City, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/13/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 02/08

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

$112

Saturday 02/14

$92

Sunday 02/15

Monday 02/16

Tuesday 02/17

Wednesday 02/18

$116

Thursday 02/19

$95

Friday 02/20

Saturday 02/21

Sunday 02/22

Monday 02/23

Tuesday 02/24

Wednesday 02/25

Thursday 02/26

Friday 02/27

Saturday 02/28

Sunday 03/01

Monday 03/02

Tuesday 03/03

Wednesday 03/04

Thursday 03/05

Friday 03/06

Saturday 03/07

The cheapest time to travel from Tuscaloosa, AL to Lake City, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Tuscaloosa, AL to Lake City, FL, for the next 30 days.

With a price starting from $92, Saturday is the cheapest day for a bus from Tuscaloosa, AL to Lake City, FL. Wednesday instead is the most expensive day with prices starting from $116.

Evening is the cheapest day time for bus tickets from Tuscaloosa, AL to Lake City, FL, with $92. Afternoon is the most expensive time of the day with prices starting from $92.

How to save money travelling from Tuscaloosa, AL to Lake City, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tuscaloosa, AL to Lake City, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tuscaloosa, AL to Lake City, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tuscaloosa, AL to Lake City, FL are also emptier.

All bus stations and stops in Tuscaloosa, AL and Lake City, FL

In the map below, you can see where to find all bus stations in Tuscaloosa, AL and Lake City, FL.

Greyhound Bus Station

Greensboro Ave

Bus Stop

Hwy 82 E 7022

I-20/Exit 73

McFarland Blvd E 4711

Embassy Suites by Hilton Tuscaloosa Alabama Dowtown

TA Gas Station

Buttermilk Rd

Bus Stop

S Marion Ave 251

Lake City Bus Stop

Service and Comfort on the bus from Tuscaloosa, AL to Lake City, FL

Want to know which seat classes are available on the buses from Tuscaloosa, AL to Lake City, FL? Or which bus companies serve the route Tuscaloosa, AL to Lake City, FL? Below you will find answers to your questions.

FAQs about the Tuscaloosa, AL to Lake City, FL bus

How much does a Tuscaloosa, AL Lake City, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $92 and takes 16h 40m to reach Lake City, FL. Compare offers to save money!

How much could I save by comparing buses from Tuscaloosa, AL to Lake City, FL?

This route is offered by 1 companies with a range of ticket prices between $92 and $117. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lake City, FL.

On average, how many connections are available from Tuscaloosa, AL to Lake City, FL each day?

Every day, the Tuscaloosa, AL to Lake City, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tuscaloosa, AL to Lake City, FL take?

The fastest bus from Tuscaloosa, AL to Lake City, FL is offered by Greyhound US and takes 15h 30m. Bus tickets for this connection cost $113. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tuscaloosa, AL to Lake City, FL?

The earliest bus arriving in Lake City, FL from Tuscaloosa, AL starts at 5:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tuscaloosa, AL to Lake City, FL?

The latest bus trip departing from Tuscaloosa, AL for Lake City, FL starts at 8:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tuscaloosa, AL Lake City, FL route?

When traveling by bus from Tuscaloosa, AL to Lake City, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tuscaloosa, AL and Lake City, FL?

You can check all the direct connections between Tuscaloosa, AL and Lake City, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Tuscaloosa, AL to Lake City, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tuscaloosa, AL Lake City, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tuscaloosa, AL Lake City, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tuscaloosa, AL to Lake City, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Tuscaloosa, AL to Lake City, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Tuscaloosa, AL and Lake City, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tuscaloosa, AL to Lake City, FL?

Prices and availability for 2 trips between Tuscaloosa, AL and Lake City, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tuscaloosa, AL to Lake City, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tuscaloosa, AL and to Lake City, FL

Here’s an overview of the most popular bus routes to Tuscaloosa, AL and to Lake City, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!