Which bus from Buffalo, NY to Lake City, FL is the cheapest?

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Compare all timetables for the bus from Buffalo, NY to Lake City, FL

Here is a selection of the cheapest bus trips from the schedule from Buffalo, NY to Lake City, FL from various bus operators like FlixBus or Greyhound US for the next days.

today
tomorrow
Friday
$215
Saturday
$212
Sunday
$212
Monday
$212
Tuesday
$212

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 34h 5m 11:05 PM Buffalo, NY Central Bus Station 9:10 AM Lake City, FL Bus Stop  Economy $215
FlixBus 30h 50m 10:30 AM Buffalo, NY Central Bus Station 5:20 PM Lake City, FL Bus Stop  Economy $241
  • Did you know that if you travel from Buffalo, NY to Lake City, FL via Tallahassee, FL, you can save more than $79? You can find the corresponding connections below.
    • Greyhound US
      38h 30m
      0
      11:05 PM
      Buffalo, NY
      Central Bus Station
      10:50 AM
      Tallahassee, FL
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $119
      • Waiting Time 0h 35m
    • Greyhound US
      2h 10m
      0
      11:25 AM
      Tallahassee, FL
      Greyhound Bus Station
      1:35 PM
      Lake City, FL
      Bus Stop
      0
      Greyhound US
      Economy
      $17
    Travel time is 7h 40m longer, but you will save $79

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 34h 5m 11:05 PM Buffalo, NY Central Bus Station 9:10 AM Lake City, FL Bus Stop  Economy $212
FlixBus 30h 50m 10:30 AM Buffalo, NY Central Bus Station 5:20 PM Lake City, FL Bus Stop  Economy $213
  • Did you know that if you travel from Buffalo, NY to Lake City, FL via Tallahassee, FL, you can save more than $76? You can find the corresponding connections below.
    • Greyhound US
      38h 30m
      0
      11:05 PM
      Buffalo, NY
      Central Bus Station
      10:50 AM
      Tallahassee, FL
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $119
      • Waiting Time 0h 35m
    • Greyhound US
      2h 10m
      0
      11:25 AM
      Tallahassee, FL
      Greyhound Bus Station
      1:35 PM
      Lake City, FL
      Bus Stop
      0
      Greyhound US
      Economy
      $17
    Travel time is 7h 40m longer, but you will save $76

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 34h 5m 11:05 PM Buffalo, NY Central Bus Station 9:10 AM Lake City, FL Bus Stop  Economy $212
FlixBus 35h 50m 5:30 AM Buffalo, NY Central Bus Station 5:20 PM Lake City, FL Bus Stop  Economy $232
  • Did you know that if you travel from Buffalo, NY to Lake City, FL via Tallahassee, FL, you can save more than $79? You can find the corresponding connections below.
    • Greyhound US
      38h 30m
      0
      11:05 PM
      Buffalo, NY
      Central Bus Station
      10:50 AM
      Tallahassee, FL
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $112
      • Waiting Time 0h 35m
    • Greyhound US
      2h 10m
      0
      11:25 AM
      Tallahassee, FL
      Greyhound Bus Station
      1:35 PM
      Lake City, FL
      Bus Stop
      0
      Greyhound US
      Economy
      $21
    Travel time is 4h 25m longer, but you will save $79

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 34h 5m 11:05 PM Buffalo, NY Central Bus Station 9:10 AM Lake City, FL Bus Stop  Economy $212
FlixBus 30h 50m 10:30 AM Buffalo, NY Central Bus Station 5:20 PM Lake City, FL Bus Stop  Economy $231
  • Did you know that if you travel from Buffalo, NY to Lake City, FL via Tallahassee, FL, you can save more than $79? You can find the corresponding connections below.
    • Greyhound US
      38h 30m
      0
      11:05 PM
      Buffalo, NY
      Central Bus Station
      10:50 AM
      Tallahassee, FL
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $112
      • Waiting Time 0h 35m
    • Greyhound US
      2h 10m
      0
      11:25 AM
      Tallahassee, FL
      Greyhound Bus Station
      1:35 PM
      Lake City, FL
      Bus Stop
      0
      Greyhound US
      Economy
      $21
    Travel time is 7h 40m longer, but you will save $79

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 34h 5m 11:05 PM Buffalo, NY Central Bus Station 9:10 AM Lake City, FL Bus Stop  Economy $212
FlixBus 30h 50m 10:30 AM Buffalo, NY Central Bus Station 5:20 PM Lake City, FL Bus Stop  Economy $213
  • Did you know that if you travel from Buffalo, NY to Lake City, FL via Tallahassee, FL, you can save more than $79? You can find the corresponding connections below.
    • Greyhound US
      38h 30m
      0
      11:05 PM
      Buffalo, NY
      Central Bus Station
      10:50 AM
      Tallahassee, FL
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $112
      • Waiting Time 0h 35m
    • Greyhound US
      2h 10m
      0
      11:25 AM
      Tallahassee, FL
      Greyhound Bus Station
      1:35 PM
      Lake City, FL
      Bus Stop
      0
      Greyhound US
      Economy
      $21
    Travel time is 7h 40m longer, but you will save $79

Best Price Offer: The price for the cheapest bus from Buffalo, NY to Lake City, FL is $209 on 11/8/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Buffalo, NY and Lake City, FL

See here how frequent the connections between Buffalo, NY and Lake City, FL are, during different times and days of the week.
Sunday is the busiest day, with more than 2 daily buses from Buffalo, NY to Lake City, FL. Sunday has instead the fewest connections, with only 2 daily coaches between Buffalo, NY and Lake City, FL.
The busiest time of the day is the Evening, with 5 buses from Buffalo, NY to Lake City, FL, while Night sees the fewest connections between Buffalo, NY and Lake City, FL, with 1 offers.

Facts about the bus from Buffalo, NY to Lake City, FL

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Buffalo, NY to Lake City, FL in one click! Book your bus ticket from Buffalo, NY to Lake City, FL starting from $209!

Cheapest Bus $209
Fastest Bus 30h 50m
Earliest Bus 10:30 AM
Latest Bus 11:05 PM
Daily Bus Routes 2 Ø
Distance 901.6 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Buffalo, NY to Lake City, FL

Every day, 2 buses from 2 bus companies leave Buffalo, NY for Lake City, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/21/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/18
Monday 10/19
Tuesday 10/20
Wednesday 10/21
Thursday 10/22
Friday 10/23
$215
Saturday 10/24
$212
Sunday 10/25
$212
Monday 10/26
$212
Tuesday 10/27
$212
Wednesday 10/28
$212
Thursday 10/29
$221
Friday 10/30
$233
Saturday 10/31
$216
Sunday 11/01
Monday 11/02
Tuesday 11/03
$210
Wednesday 11/04
Thursday 11/05
$211
Friday 11/06
Saturday 11/07
Sunday 11/08
$209
Monday 11/09
$211
Tuesday 11/10
Wednesday 11/11
Thursday 11/12
$209
Friday 11/13
Saturday 11/14

The cheapest time to travel from Buffalo, NY to Lake City, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Buffalo, NY to Lake City, FL, for the next 30 days.
With a price starting from $208, Saturday is the cheapest day for a bus from Buffalo, NY to Lake City, FL. Friday instead is the most expensive day with prices starting from $215.
Night is the cheapest day time for bus tickets from Buffalo, NY to Lake City, FL, with $208. Morning is the most expensive time of the day with prices starting from $213.

How to save money travelling from Buffalo, NY to Lake City, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buffalo, NY to Lake City, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buffalo, NY to Lake City, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buffalo, NY to Lake City, FL are also emptier.

Beloved bus companies from Buffalo, NY to Lake City, FL

These are the most booked bus companies between Buffalo, NY to Lake City, FL from our users.

FlixBus from Buffalo, NY to Lake City, FL

FlixBus

Here you will find the key facts about the FlixBus bus route Buffalo, NY to Lake City, FL:

Cheapest Price $213
Fastest Bus 30h 50m
Earliest Bus 10:30 AM
Last Bus 10:30 AM
Daily Connections 1 Ø
Found on 9/27/2026

All bus stations and stops in Buffalo, NY and Lake City, FL

In the map below, you can see where to find all bus stations in Buffalo, NY and Lake City, FL.

Service and Comfort on the bus from Buffalo, NY to Lake City, FL

Want to know which seat classes are available on the buses from Buffalo, NY to Lake City, FL? Or which bus companies serve the route Buffalo, NY to Lake City, FL? Below you will find answers to your questions.

FAQs about the Buffalo, NY to Lake City, FL bus

How much does a Buffalo, NY Lake City, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $209 and takes 34h 5m to reach Lake City, FL. Compare offers to save money!

How much could I save by comparing buses from Buffalo, NY to Lake City, FL?

This route is offered by 2 companies with a range of ticket prices between $209 and $241. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lake City, FL.

On average, how many connections are available from Buffalo, NY to Lake City, FL each day?

Every day, the Buffalo, NY to Lake City, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buffalo, NY to Lake City, FL take?

The fastest bus from Buffalo, NY to Lake City, FL is offered by FlixBus and takes 30h 50m. Bus tickets for this connection cost $241. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buffalo, NY to Lake City, FL?

The earliest bus arriving in Lake City, FL from Buffalo, NY starts at 10:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buffalo, NY to Lake City, FL?

The latest bus trip departing from Buffalo, NY for Lake City, FL starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buffalo, NY Lake City, FL route?

When traveling by bus from Buffalo, NY to Lake City, FL, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buffalo, NY and Lake City, FL?

You can check all the direct connections between Buffalo, NY and Lake City, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Buffalo, NY to Lake City, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buffalo, NY Lake City, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buffalo, NY Lake City, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buffalo, NY to Lake City, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Buffalo, NY to Lake City, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Buffalo, NY and Lake City, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Buffalo, NY to Lake City, FL?

Prices and availability for 2 trips between Buffalo, NY and Lake City, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Buffalo, NY to Lake City, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Buffalo, NY and to Lake City, FL

Here’s an overview of the most popular bus routes to Buffalo, NY and to Lake City, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Buffalo, NY and to Lake City, FL
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