What is the best way to travel from Karlsruhe to Lyon?
Looking for a trip? Compare all the available Flights, Trains and Buses for the journey to Lyon from Karlsruhe. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Karlsruhe?
You can get to Lyon with just $31 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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BlaBlaCar Bus8h 5m09:05 PMKarlsruheCentral Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/8/2026 9:05:00 PM to Perrache Train Station, Lyon (France) arriving at 10/9/2026 5:10:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 5m
Cheapest Buses Thursday
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/9/2026 12:50:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 45m
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 8:15:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 20m
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FlixBus8h 0m08:20 PMKarlsruheCentral Station4:20 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 8:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 4:20:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 0m
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BlaBlaCar Bus9h 30m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 10/9/2026 8:45:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 9h 30m
Cheapest Buses Friday
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/11/2026 8:15:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 12:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 45m
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FlixBus10h 25m010:25 AMKarlsruheCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 10:25:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 8:50:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 10h 25m
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FlixBus7h 55m03:20 PMKarlsruheCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 3:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 11:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 55m
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Ryanair18h 10m010:00 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/11/2026 4:10:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 18h 10m
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Skyscanner15h 20m07:35 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:55 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 7:35:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/11/2026 10:55:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 15h 20m
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Bringer Air Cargo Taxi Aereo22h 20m05:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 5:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/11/2026 4:10:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 22h 20m
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Bringer Air Cargo Taxi Aereo5h 10m010:25 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport3:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 10:25:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/10/2026 3:35:00 PM. 50 Economy ticket for $311 per person are available. Travel duration is 5h 10m
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TGV Lyria4h 46m03:12 PMKarlsruheCentral Station7:58 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 10/10/2026 3:12:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 10/10/2026 7:58:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 4h 46m
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TGV Lyria6h 3m09:53 AMKarlsruheCentral Station3:56 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 10/10/2026 9:53:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 10/10/2026 3:56:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 6h 3m
Cheapest Buses Saturday
Cheapest Flights Saturday
Cheapest Trains Saturday
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/11/2026 12:50:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 8h 45m
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FlixBus8h 0m08:20 PMKarlsruheCentral Station4:20 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 8:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/12/2026 4:20:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 0m
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FlixBus9h 35m012:55 AMKarlsruheCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 12:55:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/11/2026 10:30:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 9h 35m
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BlaBlaCar Bus9h 30m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 10/11/2026 8:45:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 9h 30m
Cheapest Buses Sunday
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/12/2026 12:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 45m
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FlixBus10h 25m010:25 AMKarlsruheCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 10:25:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/12/2026 8:50:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 10h 25m
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 8:15:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 20m
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FlixBus7h 55m03:20 PMKarlsruheCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 3:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/12/2026 11:15:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 7h 55m
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Skyscanner15h 45m06:15 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/12/2026 6:15:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/13/2026 10:00:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 15h 45m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 12:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 45m
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FlixBus10h 25m010:25 AMKarlsruheCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 10:25:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 8:50:00 PM. 50 Economy ticket for $33 per person are available. Travel duration is 10h 25m
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/14/2026 8:15:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 20m
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FlixBus9h 35m012:55 AMKarlsruheCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 12:55:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 10:30:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 35m
Cheapest Buses Tuesday
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/14/2026 12:50:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 8h 45m
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FlixBus10h 25m010:25 AMKarlsruheCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 10:25:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/14/2026 8:50:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 10h 25m
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BlaBlaCar Bus9h 30m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 10/14/2026 8:45:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 9h 30m
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FlixBus11h 20m05:45 PMKarlsruheCentral Station5:05 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 5:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/15/2026 5:05:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 20m
Cheapest Buses Wednesday
What are the fastest trips from Karlsruhe to Lyon?
You can get to Lyon from Karlsruhe in just 4h 46m with a Train from TGV Lyria. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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BlaBlaCar Bus8h 5m09:05 PMKarlsruheCentral Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/8/2026 9:05:00 PM to Perrache Train Station, Lyon (France) arriving at 10/9/2026 5:10:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 5m
Fastest Buses Thursday
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FlixBus8h 0m08:20 PMKarlsruheCentral Station4:20 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 8:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 4:20:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 0m
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BlaBlaCar Bus8h 5m09:05 PMKarlsruheCentral Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 9:05:00 PM to Perrache Train Station, Lyon (France) arriving at 10/10/2026 5:10:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 8h 5m
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 8:15:00 AM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/9/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/9/2026 12:50:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 8h 45m
Fastest Buses Friday
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TGV Lyria4h 46m03:12 PMKarlsruheCentral Station7:58 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 10/10/2026 3:12:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 10/10/2026 7:58:00 PM. 50 Economy ticket for $99 per person are available. Travel duration is 4h 46m
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TGV Lyria6h 3m09:53 AMKarlsruheCentral Station3:56 PMLyonPart-Dieu Train Station0EconomyA Train from TGV Lyria goes from Central Station, Karlsruhe (Germany) at 10/10/2026 9:53:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 10/10/2026 3:56:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 6h 3m
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Bringer Air Cargo Taxi Aereo5h 10m010:25 AMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport3:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 10:25:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/10/2026 3:35:00 PM. 50 Economy ticket for $311 per person are available. Travel duration is 5h 10m
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Skyscanner15h 20m07:35 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:55 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 7:35:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/11/2026 10:55:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 15h 20m
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Ryanair18h 10m010:00 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Ryanair goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 10:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/11/2026 4:10:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 18h 10m
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Bringer Air Cargo Taxi Aereo22h 20m05:50 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport4:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/10/2026 5:50:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/11/2026 4:10:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 22h 20m
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FlixBus7h 55m03:20 PMKarlsruheCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 3:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 11:15:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 7h 55m
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FlixBus8h 0m08:20 PMKarlsruheCentral Station4:20 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 8:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/11/2026 4:20:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 8h 0m
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/11/2026 8:15:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/10/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/10/2026 12:50:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 8h 45m
Fastest Trains Saturday
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus8h 0m08:20 PMKarlsruheCentral Station4:20 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 8:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/12/2026 4:20:00 AM. 50 Economy ticket for $43 per person are available. Travel duration is 8h 0m
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BlaBlaCar Bus8h 5m09:05 PMKarlsruheCentral Station5:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 9:05:00 PM to Perrache Train Station, Lyon (France) arriving at 10/12/2026 5:10:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 8h 5m
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/11/2026 12:50:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 8h 45m
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BlaBlaCar Bus9h 30m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/11/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 10/11/2026 8:45:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 9h 30m
Fastest Buses Sunday
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FlixBus7h 55m03:20 PMKarlsruheCentral Station11:15 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 3:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/12/2026 11:15:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 7h 55m
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FlixBus8h 0m08:20 PMKarlsruheCentral Station4:20 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 8:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 4:20:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 8h 0m
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 8:15:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/12/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/12/2026 12:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 45m
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Skyscanner15h 45m06:15 PMKarlsruhe/Baden-Baden AirportKarlsruhe/Baden-Baden Airport10:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Karlsruhe/Baden-Baden Airport, Karlsruhe/Baden-Baden Airport (Germany) at 10/12/2026 6:15:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 10/13/2026 10:00:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 15h 45m
Fastest Buses Monday
Fastest Flights Monday
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FlixBus8h 0m08:20 PMKarlsruheCentral Station4:20 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 8:20:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/14/2026 4:20:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 8h 0m
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FlixBus8h 20m011:55 PMKarlsruheCentral Station8:15 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 11:55:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/14/2026 8:15:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 8h 20m
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 12:50:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 45m
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FlixBus9h 35m012:55 AMKarlsruheCentral Station10:30 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/13/2026 12:55:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/13/2026 10:30:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 35m
Fastest Buses Tuesday
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FlixBus8h 45m04:05 AMKarlsruheCentral Station12:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 4:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/14/2026 12:50:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 8h 45m
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BlaBlaCar Bus9h 30m011:15 AMKarlsruheCentral Station8:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 11:15:00 AM to Perrache Train Station, Lyon (France) arriving at 10/14/2026 8:45:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 9h 30m
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FlixBus10h 25m010:25 AMKarlsruheCentral Station8:50 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 10:25:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/14/2026 8:50:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 10h 25m
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FlixBus11h 20m05:45 PMKarlsruheCentral Station5:05 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 10/14/2026 5:45:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 10/15/2026 5:05:00 AM. 50 Economy ticket for $32 per person are available. Travel duration is 11h 20m
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Here you will find all operators and timetables for a
Bus from Karlsruhe to Lyon
What are the most popular stations in Karlsruhe and Lyon?
In Karlsruhe, you will usually depart from Central Station, Heidehof Train Station or Tullastraße / Verkehrsbetriebe Train Station, while in Lyon you will be arriving at Part-Dieu Train Station, Perrache Train Station or Perrache Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Karlsruhe? With 5 connections between 4 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Karlsruhe and Lyon, you can pay as low as $31 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from TGV Lyria: you will get to Lyon in just 4h 46m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Karlsruhe and Lyon are FlixBus, BlaBlaCar Bus and TGV Lyria, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Karlsruhe and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Ettlingen or to Caluire-et-Cuire, and look at flights from Karlsruhe/Baden-Baden Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Karlsruhe to Lyon?
The most popular companies between Karlsruhe and Lyon, are FlixBus, BlaBlaCar Bus and TGV Lyria. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Train companies: TGV Lyria
Airlines: Skyscanner, Bringer Air Cargo Taxi Aereo and Ryanair
All you need to know when you travel from Karlsruhe to Lyon
Check all information on comfort and services on all modes of transports from Karlsruhe to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Karlsruhe to Lyon
How can I reach Lyon from Karlsruhe?
Every day, there are on average 5 connections between Flight, Train and Bus, with which you can get to Lyon from Karlsruhe.
How far is Lyon from Karlsruhe?
The distance between Karlsruhe and Lyon is 279.8 miles.
What is the most ecofriendly mode of transport between Karlsruhe and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 16 kgs, a car 77 kgs, and a flight 111 kgs.
What is the cheapest mode of transport from Karlsruhe to Lyon?
You can get to Lyon with just $31 by taking a Bus from FlixBus.
What is the fastest way to get from Karlsruhe to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 4h 46m with a Train from TGV Lyria.
More routes to Karlsruhe and to Lyon
Looking for more options? Here you can see the most popular routes to Karlsruhe and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Karlsruhe
- Amsterdam to Karlsruhe
- Berlin to Karlsruhe
- Braunschweig to Karlsruhe
- Darmstadt to Karlsruhe
- Dortmund to Karlsruhe
- Dusseldorf to Karlsruhe
- Essen to Karlsruhe
- Frankfurt am Main Airport to Karlsruhe
- Frankfurt am Main to Karlsruhe
- Freiburg to Karlsruhe
- Hamburg to Karlsruhe
- Hanover to Karlsruhe
- Innsbruck to Karlsruhe
- Leipzig to Karlsruhe
- Magdeburg to Karlsruhe
- Mannheim to Karlsruhe
- Milan to Karlsruhe
- Munich to Karlsruhe
- Paris to Karlsruhe
- Strasbourg to Karlsruhe
- Stuttgart Airport to Karlsruhe
- Stuttgart to Karlsruhe
- Vienna to Karlsruhe
- Warsaw to Karlsruhe
- Trips to Lyon
- Annecy to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Clermont-Ferrand to Lyon
- Cluses to Lyon
- Dusseldorf to Lyon
- Grenoble to Lyon
- La Rochelle to Lyon
- Lille to Lyon
- Marseille Airport to Lyon
- Milan to Lyon
- Montpellier to Lyon
- Mulhouse to Lyon
- Nantes to Lyon
- Narbonne to Lyon
- Nice Airport to Lyon
- Nice to Lyon
- Paris Orly Airport to Lyon
- Paris to Lyon
- Porto to Lyon
- Rennes to Lyon
- Saint-Étienne to Lyon
- Toulon to Lyon
- Vienna to Lyon
