What is the best way to travel from Mainz to Prague?
Looking for a trip? Compare all the available Buses and Flights for the journey to Prague from Mainz. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Mainz?
You can get to Prague with just $30 by taking a Bus from RegioJet, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus8h 30m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:40:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/12/2025 7:10:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:35 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:40:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 7:35:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 55m
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FlixBus9h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 11:30:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/13/2025 8:55:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 25m
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/13/2025 4:48:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 6h 48m
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/13/2025 4:45:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 6h 45m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 9:10:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 1h 0m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 10:20:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 9:35:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:00 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 5:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 6:05:00 PM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:10 AMFrankfurt am Main AirportFrankfurt am Main Airport11:15 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:10:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 11:15:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus7h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/14/2025 6:55:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 25m
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FlixBus8h 25m04:00 PMMainzCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 4:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/14/2025 12:25:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 25m
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FlixBus8h 5m04:00 PMMainzCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 4:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/14/2025 12:05:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 5m
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FlixBus10h 45m05:15 AMMainzCentral Station4:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 5:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/13/2025 4:00:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m05:15 AMMainzCentral Station3:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 5:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/13/2025 3:40:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 25m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 10:20:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 1h 0m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 3:15:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 9:50:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 6:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 2:05:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 1h 5m
Cheapest Buses Saturday
Cheapest Flights Saturday
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/15/2025 4:48:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 48m
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/15/2025 4:45:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 6h 45m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 10:20:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 9:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 9:50:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:00 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 5:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 6:05:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:25 AMFrankfurt am Main AirportFrankfurt am Main Airport11:30 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 10:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 11:30:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
Cheapest Buses Sunday
Cheapest Flights Sunday
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/16/2025 4:45:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/16/2025 4:48:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 48m
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FlixBus7h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/16/2025 6:55:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 7h 25m
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FlixBus9h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 11:30:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/16/2025 8:55:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 9h 25m
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FlixBus10h 15m01:15 AMFrankfurt am Main AirportFrankfurt am Main Airport11:30 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 1:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/15/2025 11:30:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 10h 15m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 3:15:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 9:50:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:05 AMFrankfurt am Main AirportFrankfurt am Main Airport11:10 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 10:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 11:10:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 6:15:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus10h 45m05:15 AMMainzCentral Station4:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 5:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/16/2025 4:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 45m
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FlixBus10h 25m05:15 AMMainzCentral Station3:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 5:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/16/2025 3:40:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 25m
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FlixBus11h 10m011:30 PMMainzCentral Station10:40 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/17/2025 10:40:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 10m
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FlixBus8h 25m04:00 PMMainzCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 4:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/17/2025 12:25:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 25m
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FlixBus8h 5m04:00 PMMainzCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 4:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/17/2025 12:05:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 5m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 10:20:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 0m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 3:15:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 9:35:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:00 AMFrankfurt am Main AirportFrankfurt am Main Airport11:05 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 10:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 11:05:00 AM. 50 Economy ticket for $180 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:10 PMFrankfurt am Main AirportFrankfurt am Main Airport2:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 1:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 2:15:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 1h 5m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 10:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 9:10:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 9:35:00 AM. 50 Economy ticket for $247 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 10:25:00 PM. 50 Economy ticket for $291 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 6:15:00 PM. 50 Economy ticket for $298 per person are available. Travel duration is 1h 5m
Cheapest Flights Wednesday
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FlixBus8h 55m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:35 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:40:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/18/2025 7:35:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 8h 55m
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FlixBus8h 30m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:40:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/18/2025 7:10:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m04:15 AMFrankfurt am Main AirportFrankfurt am Main Airport1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 4:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/18/2025 1:10:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 8h 55m
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FlixBus10h 15m01:15 AMFrankfurt am Main AirportFrankfurt am Main Airport11:30 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 1:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/18/2025 11:30:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 10h 15m
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FlixBus9h 55m01:15 AMFrankfurt am Main AirportFrankfurt am Main Airport11:10 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 1:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/18/2025 11:10:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 9h 55m
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Condor15h 35m04:35 PMFrankfurt am Main AirportFrankfurt am Main Airport8:10 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 4:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/19/2025 8:10:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 15h 35m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m010:00 AMFrankfurt am Main AirportFrankfurt am Main Airport11:05 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 11:05:00 AM. 50 Economy ticket for $244 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m08:40 AMFrankfurt am Main AirportFrankfurt am Main Airport9:45 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 8:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 9:45:00 AM. 50 Economy ticket for $250 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:00 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 5:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 6:05:00 PM. 50 Economy ticket for $250 per person are available. Travel duration is 1h 5m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Mainz to Prague?
You can get to Prague from Mainz in just 1h 0m with a Flight from Condor. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 9:10:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 1h 0m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 10:20:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 9:35:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:00 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 5:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 6:05:00 PM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:10 AMFrankfurt am Main AirportFrankfurt am Main Airport11:15 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:10:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/12/2025 11:15:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/13/2025 4:45:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/13/2025 4:48:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 6h 48m
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FlixBus8h 30m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:40:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/12/2025 7:10:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:35 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 10:40:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/12/2025 7:35:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 8h 55m
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FlixBus9h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/12/2025 11:30:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/13/2025 8:55:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 25m
Fastest Flights Friday
Fastest Buses Friday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 10:20:00 AM. 50 Economy ticket for $134 per person are available. Travel duration is 1h 0m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 3:15:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 9:50:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 6:15:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/13/2025 2:05:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 1h 5m
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FlixBus7h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/13/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/14/2025 6:55:00 AM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 25m
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FlixBus8h 5m04:00 PMMainzCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 4:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/14/2025 12:05:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 5m
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FlixBus8h 25m04:00 PMMainzCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 4:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/14/2025 12:25:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 25m
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FlixBus10h 25m05:15 AMMainzCentral Station3:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 5:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/13/2025 3:40:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 25m
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FlixBus10h 45m05:15 AMMainzCentral Station4:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/13/2025 5:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/13/2025 4:00:00 PM. 50 Economy ticket for $43 per person are available. Travel duration is 10h 45m
Fastest Flights Saturday
Fastest Buses Saturday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 10:20:00 AM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 9:10:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 9:50:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:00 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 5:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 6:05:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:25 AMFrankfurt am Main AirportFrankfurt am Main Airport11:30 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 10:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/14/2025 11:30:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/15/2025 4:45:00 AM. 50 Economy ticket for $35 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/14/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/15/2025 4:48:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 48m
Fastest Flights Sunday
Fastest Buses Sunday
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 3:15:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 9:50:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:05 AMFrankfurt am Main AirportFrankfurt am Main Airport11:10 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 10:05:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 11:10:00 AM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/15/2025 6:15:00 PM. 50 Economy ticket for $252 per person are available. Travel duration is 1h 5m
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/16/2025 4:45:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/16/2025 4:48:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 48m
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FlixBus7h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/16/2025 6:55:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 7h 25m
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FlixBus9h 25m011:30 PMFrankfurt am Main AirportFrankfurt am Main Airport8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 11:30:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/16/2025 8:55:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 9h 25m
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FlixBus10h 15m01:15 AMFrankfurt am Main AirportFrankfurt am Main Airport11:30 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/15/2025 1:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/15/2025 11:30:00 AM. 50 Economy ticket for $41 per person are available. Travel duration is 10h 15m
Fastest Flights Monday
Fastest Buses Monday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 10:20:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 1h 0m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 3:15:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 9:35:00 AM. 50 Economy ticket for $150 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:00 AMFrankfurt am Main AirportFrankfurt am Main Airport11:05 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 10:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 11:05:00 AM. 50 Economy ticket for $180 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:10 PMFrankfurt am Main AirportFrankfurt am Main Airport2:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/16/2025 1:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/16/2025 2:15:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 1h 5m
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FlixBus8h 5m04:00 PMMainzCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 4:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/17/2025 12:05:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 5m
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FlixBus8h 25m04:00 PMMainzCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 4:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/17/2025 12:25:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 8h 25m
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FlixBus10h 25m05:15 AMMainzCentral Station3:40 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 5:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/16/2025 3:40:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 25m
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FlixBus10h 45m05:15 AMMainzCentral Station4:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 5:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/16/2025 4:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 10h 45m
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FlixBus11h 10m011:30 PMMainzCentral Station10:40 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 12/16/2025 11:30:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/17/2025 10:40:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 11h 10m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 10:20:00 AM. 50 Economy ticket for $105 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 9:10:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 9:35:00 AM. 50 Economy ticket for $247 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 10:25:00 PM. 50 Economy ticket for $291 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/17/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/17/2025 6:15:00 PM. 50 Economy ticket for $298 per person are available. Travel duration is 1h 5m
Fastest Flights Wednesday
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 9:10:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m010:00 AMFrankfurt am Main AirportFrankfurt am Main Airport11:05 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 11:05:00 AM. 50 Economy ticket for $244 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m08:40 AMFrankfurt am Main AirportFrankfurt am Main Airport9:45 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 8:40:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 9:45:00 AM. 50 Economy ticket for $250 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:00 PMFrankfurt am Main AirportFrankfurt am Main Airport6:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 5:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/18/2025 6:05:00 PM. 50 Economy ticket for $250 per person are available. Travel duration is 1h 5m
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Condor15h 35m04:35 PMFrankfurt am Main AirportFrankfurt am Main Airport8:10 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 4:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/19/2025 8:10:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 15h 35m
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FlixBus8h 30m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:40:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/18/2025 7:10:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m010:40 AMFrankfurt am Main AirportFrankfurt am Main Airport7:35 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 10:40:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/18/2025 7:35:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 8h 55m
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FlixBus8h 55m04:15 AMFrankfurt am Main AirportFrankfurt am Main Airport1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 4:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/18/2025 1:10:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 8h 55m
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FlixBus9h 55m01:15 AMFrankfurt am Main AirportFrankfurt am Main Airport11:10 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 1:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/18/2025 11:10:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 9h 55m
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FlixBus10h 15m01:15 AMFrankfurt am Main AirportFrankfurt am Main Airport11:30 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/18/2025 1:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/18/2025 11:30:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 10h 15m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Mainz to Prague
What are the most popular stations in Mainz and Prague?
In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Prague you will be arriving at Wilsonova Bus Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Mainz? With 8 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Prague, you can pay as low as $30 with a Bus from RegioJet.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Condor: you will get to Prague in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Prague are FlixBus, Condor and Air Dolomiti, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Horoměřice, and look at flights from Frankfurt am Main Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Prague?
The most popular companies between Mainz and Prague, are FlixBus, Condor and Air Dolomiti. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Condor, Air Dolomiti and Lufthansa
All you need to know when you travel from Mainz to Prague
Check all information on comfort and services on all modes of transports from Mainz to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Prague
How can I reach Prague from Mainz?
Every day, there are on average 8 connections between Bus and Flight, with which you can get to Prague from Mainz.
How far is Prague from Mainz?
The distance between Mainz and Prague is 274.8 miles.
What is the most ecofriendly mode of transport between Mainz and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 12 kgs of CO2, a train 15 kgs, a car 75 kgs, and a flight 109 kgs.
What is the cheapest mode of transport from Mainz to Prague?
You can get to Prague with just $30 by taking a Bus from RegioJet.
What is the fastest way to get from Mainz to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 0m with a Flight from Condor.
More routes to Mainz and to Prague
Looking for more options? Here you can see the most popular routes to Mainz and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Berlin to Mainz
- Brussels to Mainz
- Dresden to Mainz
- Frankfurt am Main Airport to Mainz
- Frankfurt Hahn Airport to Mainz
- Freiburg to Mainz
- Heidelberg to Mainz
- Kaiserslautern to Mainz
- Koblenz to Mainz
- Munich to Mainz
- Paris to Mainz
- Saarbruecken to Mainz
- Simmern (Hunsrück) to Mainz
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bratislava to Prague
- Brno to Prague
- Chemnitz to Prague
- Dresden to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Memmingen to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Presov to Prague
- Regensburg to Prague
- Teplice to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague

