What is the best way to travel from Lyon to Prague?
Looking for a trip? Compare all the available Buses and Flights for the journey to Prague from Lyon. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Lyon?
You can get to Prague with just $62 by taking a Bus from BlaBlaCar Bus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/26/2025 8:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 14h 40m
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FlixBus15h 5m06:15 PMLyonPerrache Bus Stop9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/26/2025 9:20:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 15h 5m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/26/2025 1:55:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 55m
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FlixBus17h 5m09:00 PMLyonPerrache Bus Stop2:05 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/26/2025 2:05:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 5m
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FlixBus17h 25m010:00 PMLyonPerrache Bus Stop3:25 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/26/2025 3:25:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 25m
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EasyJet Airline10h 50m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 7:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/25/2025 5:50:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 10h 50m
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Volotea27h 25m08:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 8:25:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/26/2025 11:50:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 25m
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LOT Polish Airlines / Polskie Linie Lotnicze26h 20m07:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 7:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/26/2025 9:40:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 26h 20m
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Lufthansa CityLine3h 30m09:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 9:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/25/2025 12:55:00 PM. 50 Economy ticket for $208 per person are available. Travel duration is 3h 30m
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AirBaltic8h 20m01:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from AirBaltic goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/25/2025 9:20:00 PM. 50 Economy ticket for $208 per person are available. Travel duration is 8h 20m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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FlixBus15h 50m05:05 PMLyons St. Exupery AirportLyons St. Exupery Airport8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 6/26/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/27/2025 8:55:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 15h 50m
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FlixBus16h 15m05:05 PMLyons St. Exupery AirportLyons St. Exupery Airport9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 6/26/2025 5:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 9:20:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 16h 15m
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/26/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/27/2025 8:55:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 14h 40m
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FlixBus15h 5m06:15 PMLyonPerrache Bus Stop9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/26/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 9:20:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 5m
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FlixBus17h 45m05:05 PMLyons St. Exupery AirportLyons St. Exupery Airport10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 6/26/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/27/2025 10:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 17h 45m
Cheapest Buses Thursday
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Bus Stop7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Train Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 6/27/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/28/2025 8:55:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 40m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/28/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 16h 55m
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FlixBus15h 5m06:15 PMLyonPerrache Bus Stop9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/28/2025 9:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 15h 5m
Cheapest Buses Friday
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Train Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 6/28/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/28/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Bus Stop7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/28/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/29/2025 8:55:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 40m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/29/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 16h 55m
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RegioJet15h 50m02:35 PMLyonPerrache Bus Stop6:25 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 2:35:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 6/29/2025 6:25:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 15h 50m
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EasyJet Airline14h 0m09:50 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 9:50:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 11:50:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 14h 0m
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Vueling Airlines10h 35m09:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 7:55:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 10h 35m
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Volotea13h 35m06:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 6:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 8:05:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 13h 35m
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AirBaltic8h 20m01:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from AirBaltic goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 9:20:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 8h 20m
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Lufthansa CityLine11h 55m09:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 9:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 9:20:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 11h 55m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus17h 35m05:20 AMLyonPerrache Bus Stop10:55 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 5:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/29/2025 10:55:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 35m
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FlixBus19h 0m03:15 AMLyonPerrache Bus Stop10:15 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 3:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/29/2025 10:15:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 0m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/30/2025 1:55:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 16h 55m
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FlixBus17h 5m09:00 PMLyonPerrache Bus Stop2:05 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 2:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 5m
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FlixBus17h 25m010:00 PMLyonPerrache Bus Stop3:25 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 3:25:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 25m
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Volotea29h 5m08:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:15 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 1:15:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 29h 5m
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EasyJet Airline13h 5m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 7:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/29/2025 8:05:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 13h 5m
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LC Perú12h 20m09:45 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 9:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/29/2025 10:05:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 12h 20m
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LOT Polish Airlines / Polskie Linie Lotnicze13h 55m07:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:15 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 7:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/30/2025 9:15:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 13h 55m
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Norwegian Air International22h 0m011:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Norwegian Air International goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 11:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/30/2025 9:00:00 AM. 50 Economy ticket for $195 per person are available. Travel duration is 22h 0m
Cheapest Buses Sunday
Cheapest Flights Sunday
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Bus Stop7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Train Station7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 6/30/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus20h 50m02:10 AMLyonPerrache Bus Stop11:00 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 2:10:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 11:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 20h 50m
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FlixBus19h 45m01:25 AMLyonPerrache Bus Stop9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 1:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/30/2025 9:10:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 45m
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FlixBus19h 0m03:15 AMLyonPerrache Bus Stop10:15 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 3:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/30/2025 10:15:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 0m
Cheapest Buses Monday
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Train Station7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/1/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/1/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Bus Stop7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 7/1/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/1/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus20h 50m02:10 AMLyonPerrache Train Station11:00 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/1/2025 2:10:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/1/2025 11:00:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 20h 50m
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 7/1/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/2/2025 8:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 14h 40m
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FlixBus18h 45m03:30 AMLyonPerrache Bus Stop10:15 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 7/1/2025 3:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/1/2025 10:15:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 18h 45m
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Volotea8h 10m03:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 3:40:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 11:50:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 8h 10m
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EasyJet Airline10h 5m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 7:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 5:05:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 10h 5m
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Wizz Air18h 15m09:45 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 9:45:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/2/2025 4:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 18h 15m
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LOT Polish Airlines / Polskie Linie Lotnicze5h 50m011:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 11:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 5:20:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 5h 50m
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Lufthansa CityLine3h 30m05:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 5:50:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 9:20:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 3h 30m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
What are the fastest trips from Lyon to Prague?
You can get to Prague from Lyon in just 3h 30m with a Flight from Lufthansa CityLine. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Lufthansa CityLine3h 30m09:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station12:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 9:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/25/2025 12:55:00 PM. 50 Economy ticket for $208 per person are available. Travel duration is 3h 30m
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AirBaltic8h 20m01:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from AirBaltic goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/25/2025 9:20:00 PM. 50 Economy ticket for $208 per person are available. Travel duration is 8h 20m
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EasyJet Airline10h 50m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 7:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/25/2025 5:50:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 10h 50m
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LOT Polish Airlines / Polskie Linie Lotnicze26h 20m07:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:40 PMPrague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 7:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/26/2025 9:40:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 26h 20m
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Volotea27h 25m08:25 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/25/2025 8:25:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/26/2025 11:50:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 27h 25m
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/26/2025 8:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 14h 40m
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FlixBus15h 5m06:15 PMLyonPerrache Bus Stop9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/26/2025 9:20:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 15h 5m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/26/2025 1:55:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 55m
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FlixBus17h 5m09:00 PMLyonPerrache Bus Stop2:05 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/26/2025 2:05:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 5m
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FlixBus17h 25m010:00 PMLyonPerrache Bus Stop3:25 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/25/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/26/2025 3:25:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 17h 25m
Fastest Flights Wednesday
Fastest Buses Wednesday
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/26/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/27/2025 8:55:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 14h 40m
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FlixBus15h 5m06:15 PMLyonPerrache Bus Stop9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/26/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 9:20:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 5m
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FlixBus15h 50m05:05 PMLyons St. Exupery AirportLyons St. Exupery Airport8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 6/26/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/27/2025 8:55:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 15h 50m
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FlixBus16h 15m05:05 PMLyons St. Exupery AirportLyons St. Exupery Airport9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 6/26/2025 5:05:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 9:20:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 16h 15m
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FlixBus17h 45m05:05 PMLyons St. Exupery AirportLyons St. Exupery Airport10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 6/26/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/27/2025 10:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 17h 45m
Fastest Buses Thursday
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/28/2025 8:55:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 40m
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FlixBus15h 5m06:15 PMLyonPerrache Bus Stop9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/28/2025 9:20:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 15h 5m
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Bus Stop7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Train Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 6/27/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/27/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/27/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/28/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 16h 55m
Fastest Buses Friday
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AirBaltic8h 20m01:00 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from AirBaltic goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 9:20:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 8h 20m
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Vueling Airlines10h 35m09:20 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station7:55 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 7:55:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 10h 35m
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Lufthansa CityLine11h 55m09:25 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 9:25:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 9:20:00 PM. 50 Economy ticket for $210 per person are available. Travel duration is 11h 55m
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Volotea13h 35m06:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 6:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 8:05:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 13h 35m
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EasyJet Airline14h 0m09:50 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/28/2025 9:50:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/28/2025 11:50:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 14h 0m
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/29/2025 8:55:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 40m
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RegioJet15h 50m02:35 PMLyonPerrache Bus Stop6:25 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 2:35:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 6/29/2025 6:25:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 15h 50m
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Train Station7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 6/28/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/28/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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BlaBlaCar Bus16h 25m03:00 AMLyonPerrache Bus Stop7:25 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/28/2025 7:25:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 25m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/28/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/29/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 16h 55m
Fastest Flights Saturday
Fastest Buses Saturday
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LC Perú12h 20m09:45 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station10:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from LC Perú goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 9:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/29/2025 10:05:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 12h 20m
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EasyJet Airline13h 5m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station8:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 7:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/29/2025 8:05:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 13h 5m
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LOT Polish Airlines / Polskie Linie Lotnicze13h 55m07:20 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:15 AMPrague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 7:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/30/2025 9:15:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 13h 55m
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Norwegian Air International22h 0m011:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:00 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Norwegian Air International goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 11:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 6/30/2025 9:00:00 AM. 50 Economy ticket for $195 per person are available. Travel duration is 22h 0m
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Volotea29h 5m08:10 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station1:15 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 6/29/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 1:15:00 AM. 50 Economy ticket for $122 per person are available. Travel duration is 29h 5m
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FlixBus16h 55m09:00 PMLyonPerrache Bus Stop1:55 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/30/2025 1:55:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 16h 55m
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FlixBus17h 5m09:00 PMLyonPerrache Bus Stop2:05 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 2:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 5m
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FlixBus17h 25m010:00 PMLyonPerrache Bus Stop3:25 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 3:25:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 25m
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FlixBus17h 35m05:20 AMLyonPerrache Bus Stop10:55 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 5:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/29/2025 10:55:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 35m
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FlixBus19h 0m03:15 AMLyonPerrache Bus Stop10:15 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/29/2025 3:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/29/2025 10:15:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 19h 0m
Fastest Flights Sunday
Fastest Buses Sunday
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Bus Stop7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Train Station7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 6/30/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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FlixBus19h 0m03:15 AMLyonPerrache Bus Stop10:15 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 3:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 6/30/2025 10:15:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 0m
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FlixBus19h 45m01:25 AMLyonPerrache Bus Stop9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 1:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 6/30/2025 9:10:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 19h 45m
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BlaBlaCar Bus20h 50m02:10 AMLyonPerrache Bus Stop11:00 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 6/30/2025 2:10:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 6/30/2025 11:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 20h 50m
Fastest Buses Monday
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Lufthansa CityLine3h 30m05:50 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station9:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 5:50:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 9:20:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 3h 30m
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LOT Polish Airlines / Polskie Linie Lotnicze5h 50m011:30 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:20 PMPrague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 11:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 5:20:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 5h 50m
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Volotea8h 10m03:40 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station11:50 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Volotea goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 3:40:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 11:50:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 8h 10m
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EasyJet Airline10h 5m07:00 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station5:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 7:00:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/1/2025 5:05:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 10h 5m
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Wizz Air18h 15m09:45 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station4:00 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) at 7/1/2025 9:45:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 7/2/2025 4:00:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 18h 15m
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FlixBus14h 40m06:15 PMLyonPerrache Bus Stop8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 7/1/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 7/2/2025 8:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 14h 40m
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Train Station7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/1/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/1/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus16h 45m03:00 AMLyonPerrache Bus Stop7:45 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 7/1/2025 3:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/1/2025 7:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 16h 45m
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FlixBus18h 45m03:30 AMLyonPerrache Bus Stop10:15 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 7/1/2025 3:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 7/1/2025 10:15:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 18h 45m
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BlaBlaCar Bus20h 50m02:10 AMLyonPerrache Train Station11:00 PMPragueÚAN Florenc0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 7/1/2025 2:10:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 7/1/2025 11:00:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 20h 50m
Fastest Flights Tuesday
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from Lyon to Prague
What are the most popular stations in Lyon and Prague?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Prague you will be arriving at ÚAN Florenc, Train station Wilsonova or Holešovice zastávka Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Lyon? With 7 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Prague, you can pay as low as $62 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa CityLine: you will get to Prague in just 3h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Prague are FlixBus, BlaBlaCar Bus and EasyJet Airline, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Horoměřice, and look at flights from Lyons St. Exupery Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Prague?
The most popular companies between Lyon and Prague, are FlixBus, BlaBlaCar Bus and EasyJet Airline. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, BlaBlaCar Bus and RegioJet
Airlines: EasyJet Airline, Volotea, LOT Polish Airlines / Polskie Linie Lotnicze and 6 more.
All you need to know when you travel from Lyon to Prague
Check all information on comfort and services on all modes of transports from Lyon to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Prague
How can I reach Prague from Lyon?
Every day, there are on average 7 connections between Bus and Flight, with which you can get to Prague from Lyon.
How far is Prague from Lyon?
The distance between Lyon and Prague is 535.0 miles.
What is the most ecofriendly mode of transport between Lyon and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 23 kgs of CO2, a train 30 kgs, a car 146 kgs, and a flight 212 kgs.
What is the cheapest mode of transport from Lyon to Prague?
You can get to Prague with just $62 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Lyon to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 3h 30m with a Flight from Lufthansa CityLine.
More routes to Lyon and to Prague
Looking for more options? Here you can see the most popular routes to Lyon and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Biarritz to Lyon
- Bilbao to Lyon
- Bordeaux to Lyon
- Geneva Airport to Lyon
- Geneva to Lyon
- Lausanne to Lyon
- Lille to Lyon
- Lisbon to Lyon
- London to Lyon
- Madrid to Lyon
- Marseille to Lyon
- Metz to Lyon
- Nantes to Lyon
- Nimes to Lyon
- Paris to Lyon
- Rennes to Lyon
- Saint-Étienne to Lyon
- Toulon to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valence to Lyon
- Valencia to Lyon
- Trips to Prague
- Amsterdam to Prague
- Berlin Brandenburg Airport to Prague
- Bielsko-Biala to Prague
- Bratislava to Prague
- Brno to Prague
- Cologne to Prague
- Dresden to Prague
- Frankfurt am Main to Prague
- Humpolec to Prague
- Karlovy Vary to Prague
- Krakow to Prague
- Livorno to Prague
- London to Prague
- Nuremberg to Prague
- Ostrava to Prague
- Paris to Prague
- Pilsen to Prague
- Pisek to Prague
- Presov to Prague
- Těšovice to Prague
- Turin to Prague
- Warsaw to Prague
- Ziar nad Hronom to Prague
- Zurich to Prague