Compare all timetables for the bus from Lyon to Prague
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 5m | 6:15 PM | Lyon | Perrache Bus Stop | 9:20 AM | Prague | ÚAN Florenc | Economy | $71 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/5/2025 9:20:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 15h 5m
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| FlixBus | 14h 40m | 6:15 PM | Lyon | Perrache Bus Stop | 8:55 AM | Prague | Na Knížecí Station | Economy | $71 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/5/2025 8:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 14h 40m
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| FlixBus | 16h 55m | 9:00 PM | Lyon | Perrache Bus Stop | 1:55 PM | Prague | Wilsonova Bus Station | Economy | $81 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/5/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 16h 55m
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| FlixBus | 17h 5m | 9:00 PM | Lyon | Perrache Bus Stop | 2:05 PM | Prague | ÚAN Florenc | Economy | $81 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/5/2025 2:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 17h 5m
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| FlixBus | 20h 30m | 9:30 AM | Lyon | Perrache Bus Stop | 6:00 AM | Prague | Wilsonova Bus Station | Economy | $88 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/4/2025 9:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/5/2025 6:00:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 20h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 14h 40m | 6:15 PM | Lyon | Perrache Bus Stop | 8:55 AM | Prague | Na Knížecí Station | Economy | $77 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/6/2025 8:55:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 14h 40m
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| FlixBus | 15h 5m | 6:15 PM | Lyon | Perrache Bus Stop | 9:20 AM | Prague | ÚAN Florenc | Economy | $77 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/6/2025 9:20:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 5m
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| FlixBus | 16h 55m | 9:00 PM | Lyon | Perrache Bus Stop | 1:55 PM | Prague | Wilsonova Bus Station | Economy | $79 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/6/2025 1:55:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 16h 55m
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| FlixBus | 17h 5m | 9:00 PM | Lyon | Perrache Bus Stop | 2:05 PM | Prague | ÚAN Florenc | Economy | $79 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/6/2025 2:05:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 5m
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| FlixBus | 16h 30m | 5:20 AM | Lyon | Perrache Bus Stop | 9:50 PM | Prague | ÚAN Florenc | Economy | $81 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/5/2025 5:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/5/2025 9:50:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 16h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 14h 40m | 6:15 PM | Lyon | Perrache Bus Stop | 8:55 AM | Prague | Na Knížecí Station | Economy | $69 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/7/2025 8:55:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 40m
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| FlixBus | 15h 5m | 6:15 PM | Lyon | Perrache Bus Stop | 9:20 AM | Prague | ÚAN Florenc | Economy | $69 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/7/2025 9:20:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 25m | 10:00 PM | Lyon | Perrache Bus Stop | 3:25 PM | Prague | ÚAN Florenc | Economy | $71 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/7/2025 3:25:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 17h 25m
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| FlixBus | 18h 10m | 10:00 PM | Lyon | Perrache Bus Stop | 4:10 PM | Prague | Černý Most | Economy | $71 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 10:00:00 PM to Černý Most, Prague (Czech Republic) arriving at 12/7/2025 4:10:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 18h 10m
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| FlixBus | 18h 45m | 3:30 AM | Lyon | Perrache Bus Stop | 10:15 PM | Prague | Wilsonova Bus Station | Economy | $72 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/6/2025 3:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/6/2025 10:15:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 18h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 17h 25m | 10:00 PM | Lyon | Perrache Bus Stop | 3:25 PM | Prague | ÚAN Florenc | Economy | $72 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/8/2025 3:25:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 17h 25m
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| FlixBus | 18h 10m | 10:00 PM | Lyon | Perrache Bus Stop | 4:10 PM | Prague | Černý Most | Economy | $72 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 10:00:00 PM to Černý Most, Prague (Czech Republic) arriving at 12/8/2025 4:10:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 18h 10m
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| FlixBus | 15h 5m | 6:15 PM | Lyon | Perrache Bus Stop | 9:20 AM | Prague | ÚAN Florenc | Economy | $74 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/8/2025 9:20:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 15h 5m
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| FlixBus | 14h 40m | 6:15 PM | Lyon | Perrache Bus Stop | 8:55 AM | Prague | Na Knížecí Station | Economy | $74 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/8/2025 8:55:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 14h 40m
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| FlixBus | 16h 55m | 9:00 PM | Lyon | Perrache Bus Stop | 1:55 PM | Prague | Wilsonova Bus Station | Economy | $77 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/7/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/8/2025 1:55:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 55m
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FlixBus18h 45m03:30 AMLyonPerrache Bus Stop9:50 AMZurichCentral Bus Station Sihlquai0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 3:30:00 AM to Central Bus Station Sihlquai, Zurich (Switzerland) arriving at 12/9/2025 9:50:00 AM. 50 Economy ticket for $24 per person are available. Travel duration is 6h 20m
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FlixBus11h 0m011:15 AMZurichCentral Bus Station Sihlquai10:15 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station Sihlquai, Zurich (Switzerland) at 12/9/2025 11:15:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/9/2025 10:15:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 11h 0m
Waiting Time 1h 25m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 20h 30m | 9:30 AM | Lyon | Perrache Bus Stop | 6:00 AM | Prague | Wilsonova Bus Station | Economy | $59 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 9:30:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/9/2025 6:00:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 20h 30m
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| FlixBus | 20h 45m | 9:30 AM | Lyon | Perrache Bus Stop | 6:15 AM | Prague | ÚAN Florenc | Economy | $59 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 9:30:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/9/2025 6:15:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 20h 45m
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| FlixBus | 17h 35m | 5:20 AM | Lyon | Perrache Bus Stop | 10:55 PM | Prague | Na Knížecí Station | Economy | $59 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 5:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/8/2025 10:55:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 35m
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| BlaBlaCar Bus | 21h 45m | 12:00 PM | Lyon | Perrache Bus Stop | 9:45 AM | Prague | ÚAN Florenc | Economy | $77 |
A Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 12/8/2025 12:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/9/2025 9:45:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 21h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 5m | 6:15 PM | Lyon | Perrache Bus Stop | 9:20 AM | Prague | ÚAN Florenc | Economy | $56 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 6:15:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/10/2025 9:20:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 15h 5m
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| FlixBus | 14h 40m | 6:15 PM | Lyon | Perrache Bus Stop | 8:55 AM | Prague | Na Knížecí Station | Economy | $56 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 6:15:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/10/2025 8:55:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 14h 40m
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| FlixBus | 16h 55m | 9:00 PM | Lyon | Perrache Bus Stop | 1:55 PM | Prague | Wilsonova Bus Station | Economy | $57 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/10/2025 1:55:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 16h 55m
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| FlixBus | 17h 5m | 9:00 PM | Lyon | Perrache Bus Stop | 2:05 PM | Prague | ÚAN Florenc | Economy | $57 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/10/2025 2:05:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 17h 5m
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| FlixBus | 19h 5m | 5:20 AM | Lyon | Perrache Bus Stop | 12:25 AM | Prague | Wilsonova Bus Station | Economy | $60 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/9/2025 5:20:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/10/2025 12:25:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 19h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 35m | 7:20 AM | Lyon | Perrache Bus Stop | 6:55 AM | Prague | ÚAN Florenc | Economy | $63 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 7:20:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/11/2025 6:55:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 23h 35m
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| FlixBus | 20h 30m | 2:25 AM | Lyon | Perrache Bus Stop | 10:55 PM | Prague | Na Knížecí Station | Economy | $65 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 2:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/10/2025 10:55:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 20h 30m
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| FlixBus | 17h 5m | 9:00 PM | Lyon | Perrache Bus Stop | 2:05 PM | Prague | ÚAN Florenc | Economy | $69 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 9:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/11/2025 2:05:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 17h 5m
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| FlixBus | 16h 55m | 9:00 PM | Lyon | Perrache Bus Stop | 1:55 PM | Prague | Wilsonova Bus Station | Economy | $69 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 9:00:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/11/2025 1:55:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 16h 55m
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| FlixBus | 24h 20m | 7:20 AM | Lyon | Perrache Bus Stop | 7:40 AM | Prague | Na Knížecí Station | Economy | $70 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/10/2025 7:20:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/11/2025 7:40:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 24h 20m
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Best Price Offer: The price for the cheapest bus from Lyon to Prague is $56 on 12/9/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Lyon and Prague
Facts about the bus from Lyon to Prague
Compare all providers like FlixBus and BlaBlaCar Bus that travel 10 times every day by bus from Lyon to Prague in one click! Book your bus ticket from Lyon to Prague starting from $56!
| Cheapest Bus | $56 |
| Fastest Bus | 14h 40m |
| Earliest Bus | 9:30 AM |
| Latest Bus | 9:00 PM |
| Daily Bus Routes | 10 Ø |
| Distance | 535.0 miles |
| Bus Companies | FlixBus and BlaBlaCar Bus |
Cheapest bus connections from Lyon to Prague
Every day, 10 buses from 2 bus companies leave Lyon for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.
The cheapest time to travel from Lyon to Prague
How to save money travelling from Lyon to Prague
Book the ticket from Lyon to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Prague, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Prague are also emptier.Latest reviews for bus companies on the route Lyon - Prague
All bus stations and stops in Lyon and Prague
In the map below, you can see where to find all bus stations in Lyon and Prague.
Compare the bus with other modes of transport
Service and Comfort on the bus from Lyon to Prague
FAQs about the Lyon to Prague bus
How much does a Lyon Prague bus trip cost?
How much could I save by comparing buses from Lyon to Prague?
On average, how many connections are available from Lyon to Prague each day?
How long does a bus journey from Lyon to Prague take?
What time is the first bus from Lyon to Prague?
What time is the last bus from Lyon to Prague?
Which bus companies operate the Lyon Prague route?
Is there a direct bus between Lyon and Prague?
What can I take with me on the Lyon to Prague bus route?
What equipment is available for the Lyon Prague bus route?
Available seat classes which are offered on the bus route Lyon to Prague
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Lyon and to Prague
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