Bus from Rome to Prague from $68

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Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus for the next days.

today
$81
tomorrow
$100
Thursday
$92
Friday
$91
Saturday
$102
Sunday
$96
Monday
$79

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 28h 30m 1:05 PM Rome Anagnina Bus Station 5:35 PM Prague Hradčanská  Economy $81
FlixBus 25h 40m 11:50 AM Rome Anagnina Bus Station 1:30 PM Prague ÚAN Florenc  Economy $95
FlixBus 24h 20m 11:50 AM Rome Anagnina Bus Station 12:10 PM Prague Wilsonova Bus Station  Economy $95
FlixBus 28h 20m 11:50 AM Rome Anagnina Bus Station 4:10 PM Prague Černý Most  Economy $96
FlixBus 24h 55m 11:50 AM Rome Anagnina Bus Station 12:45 PM Prague Na Knížecí Station  Economy $96

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 40m 11:35 PM Rome Anagnina Bus Station 3:15 AM Prague Wilsonova Bus Station  Economy $100
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $106
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $106
FlixBus 25h 45m 5:25 PM Rome Anagnina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $110
FlixBus 26h 55m 9:00 PM Rome Tiburtina Bus Station 11:55 PM Prague Wilsonova Bus Station  Economy $111
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      24h 25m
      0
      1:05 PM
      Rome
      Anagnina Bus Station
      11:40 PM
      Udine
      Train Station
      0
      FlixBus
      Economy
      $36
      • Waiting Time 0h 5m
    • FlixBus
      13h 45m
      0
      11:45 PM
      Udine
      Train Station
      1:30 PM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $51
    Travel time is 3h 45m longer, but you will save $13

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 40m 11:35 PM Rome Anagnina Bus Station 3:15 AM Prague Wilsonova Bus Station  Economy $92
FlixBus 22h 10m 9:00 PM Rome Tiburtina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $94
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $95
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $95
FlixBus 26h 55m 9:00 PM Rome Tiburtina Bus Station 11:55 PM Prague Wilsonova Bus Station  Economy $95

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 40m 11:35 PM Rome Anagnina Bus Station 3:15 AM Prague Wilsonova Bus Station  Economy $91
FlixBus 26h 55m 9:00 PM Rome Tiburtina Bus Station 11:55 PM Prague Wilsonova Bus Station  Economy $93
FlixBus 22h 10m 9:00 PM Rome Tiburtina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $93
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $95
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $95

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 55m 10:55 PM Rome Tiburtina Bus Station 2:50 AM Prague Wilsonova Bus Station  Economy $102
FlixBus 24h 0m 10:55 PM Rome Tiburtina Bus Station 10:55 PM Prague Na Knížecí Station  Economy $102
FlixBus 20h 50m 5:05 PM Rome Tiburtina Bus Station 1:55 PM Prague ÚAN Florenc  Economy $106
FlixBus 20h 40m 5:05 PM Rome Tiburtina Bus Station 1:45 PM Prague Wilsonova Bus Station  Economy $106
FlixBus 27h 40m 11:35 PM Rome Anagnina Bus Station 3:15 AM Prague Wilsonova Bus Station  Economy $106
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $26? You can find the corresponding connections below.
    • FlixBus
      24h 25m
      0
      1:05 PM
      Rome
      Anagnina Bus Station
      11:40 PM
      Udine
      Train Station
      0
      FlixBus
      Economy
      $34
      • Waiting Time 0h 5m
    • FlixBus
      13h 45m
      0
      11:45 PM
      Udine
      Train Station
      1:30 PM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $41
    Travel time is 3h 45m longer, but you will save $26

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 26h 55m 9:00 PM Rome Tiburtina Bus Station 11:55 PM Prague Wilsonova Bus Station  Economy $96
FlixBus 22h 10m 9:00 PM Rome Tiburtina Bus Station 7:10 PM Prague Na Knížecí Station  Economy $98
FlixBus 27h 0m 5:00 PM Rome Tiburtina Bus Station 8:00 PM Prague Wilsonova Bus Station  Economy $100
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $107
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $107
  • Did you know that if you travel from Rome to Prague via Udine, you can save more than $20? You can find the corresponding connections below.
    • FlixBus
      24h 25m
      0
      1:05 PM
      Rome
      Anagnina Bus Station
      11:40 PM
      Udine
      Train Station
      0
      FlixBus
      Economy
      $34
      • Waiting Time 0h 5m
    • FlixBus
      13h 45m
      0
      11:45 PM
      Udine
      Train Station
      1:30 PM
      Prague
      Roztyly
      0
      FlixBus
      Economy
      $41
    Travel time is 3h 55m longer, but you will save $20

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 40m 11:35 PM Rome Anagnina Bus Station 3:15 AM Prague Wilsonova Bus Station  Economy $79
FlixBus 22h 45m 11:50 AM Rome Tiburtina Bus Station 10:35 AM Prague Wilsonova Bus Station  Economy $81
FlixBus 27h 0m 5:00 PM Rome Tiburtina Bus Station 8:00 PM Prague Wilsonova Bus Station  Economy $81
FlixBus 26h 55m 9:00 PM Rome Tiburtina Bus Station 11:55 PM Prague Wilsonova Bus Station  Economy $81
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $82

Best Price Offer: The price for the cheapest bus from Rome to Prague is $68 on 5/28/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.
Friday is the busiest day, with more than 46 daily buses from Rome to Prague. Tuesday has instead the fewest connections, with only 19 daily coaches between Rome and Prague.
The busiest time of the day is the Afternoon, with 121 buses from Rome to Prague, while Morning sees the fewest connections between Rome and Prague, with 54 offers.

Facts about the bus from Rome to Prague

Compare all providers like FlixBus that travel 36 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from $68!

Cheapest Bus $68
Fastest Bus 19h 55m
Earliest Bus 11:50 AM
Latest Bus 11:50 PM
Daily Bus Routes 36 Ø
Distance 572.5 miles
Bus Companies FlixBus

Cheapest bus connections from Rome to Prague

Every day, 36 buses from 1 bus companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/03
Monday 05/04
Tuesday 05/05
$121
Wednesday 05/06
$100
Thursday 05/07
$92
Friday 05/08
$91
Saturday 05/09
$102
Sunday 05/10
$96
Monday 05/11
$79
Tuesday 05/12
$74
Wednesday 05/13
$71
Thursday 05/14
$79
Friday 05/15
$74
Saturday 05/16
$79
Sunday 05/17
$85
Monday 05/18
$72
Tuesday 05/19
$76
Wednesday 05/20
$72
Thursday 05/21
$72
Friday 05/22
$74
Saturday 05/23
$70
Sunday 05/24
$77
Monday 05/25
$72
Tuesday 05/26
$75
Wednesday 05/27
$69
Thursday 05/28
$68
Friday 05/29
$78
Saturday 05/30

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.
With a price starting from $68, Thursday is the cheapest day for a bus from Rome to Prague. Sunday instead is the most expensive day with prices starting from $77.
Evening is the cheapest day time for bus tickets from Rome to Prague, with $79. Morning is the most expensive time of the day with prices starting from $81.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Prague are also emptier.

All bus stations and stops in Rome and Prague

In the map below, you can see where to find all bus stations in Rome and Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the buses from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $68 and takes 27h 40m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Rome to Prague?

This route is offered by 1 companies with a range of ticket prices between $68 and $169. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Rome to Prague each day?

Every day, the Rome to Prague bus route is served by approximately 36 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Prague take?

The fastest bus from Rome to Prague is offered by FlixBus and takes 19h 55m. Bus tickets for this connection cost $113. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus arriving in Prague from Rome starts at 11:50 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Prague?

The latest bus trip departing from Rome for Prague starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Prague route?

When traveling by bus from Rome to Prague, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Rome to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Prague?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 36 daily trips between Rome and Prague. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Prague?

Prices and availability for 36 trips between Rome and Prague change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Taranto to Rome Bus Taranto to Rome
From Trieste to Rome bus From Trieste to Rome bus
Bus to Rome from Castel San Giorgio Bus to Rome from Castel San Giorgio
Bus Ascoli Piceno to Rome Bus Ascoli Piceno to Rome
Bus from Haskovo to Prague Bus from Haskovo to Prague
Bus to Prague from Zadar Bus to Prague from Zadar
Buses from Banska Bystrica to Prague Buses from Banska Bystrica to Prague
Buses to Prague from Teplice Buses to Prague from Teplice
Popular Airport Shuttles to Rome and to Prague
CheckMyBus › Buses in Italy › Bus to Rome › Bus to Prague

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