Bus from Rome to Prague from $65

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Compare all timetables for the bus from Rome to Prague

Here is a selection of the cheapest bus trips from the schedule from Rome to Prague from various bus operators like FlixBus or RegioJet for the next days.

today
$125
tomorrow
$102
Saturday
$102
Sunday
$105
Monday
$91
Tuesday
$80
Wednesday
$65

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 45m 9:30 AM Rome Tiburtina Bus Station 6:15 AM Prague ÚAN Florenc  Economy $125
FlixBus 20h 30m 9:30 AM Rome Tiburtina Bus Station 6:00 AM Prague Wilsonova Bus Station  Economy $125
FlixBus 24h 30m 5:05 PM Rome Tiburtina Bus Station 5:35 PM Prague Hradčanská  Economy $126
FlixBus 24h 10m 5:25 PM Rome Anagnina Bus Station 5:35 PM Prague Hradčanská  Economy $126
FlixBus 23h 30m 11:05 PM Rome Tiburtina Bus Station 10:35 PM Prague Roztyly  Economy $132

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $102
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $102
FlixBus 24h 20m 5:25 PM Rome Anagnina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $106
FlixBus 24h 5m 5:25 PM Rome Anagnina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $107
FlixBus 28h 30m 5:25 PM Rome Anagnina Bus Station 9:55 PM Prague Černý Most  Economy $108

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 30m 10:15 AM Rome Tiburtina Bus Station 8:45 AM Prague ÚAN Florenc  Economy $102
FlixBus 22h 0m 10:15 AM Rome Tiburtina Bus Station 8:15 AM Prague Roztyly  Economy $102
FlixBus 22h 45m 5:25 PM Rome Anagnina Bus Station 4:10 PM Prague Černý Most  Economy $102
FlixBus 23h 50m 10:15 AM Rome Tiburtina Bus Station 10:05 AM Prague Na Knížecí Station  Economy $103
FlixBus 23h 20m 9:00 PM Rome Tiburtina Bus Station 8:20 PM Prague Na Knížecí Station  Economy $103

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 35m 1:40 AM Rome Tiburtina Bus Station 3:15 AM Prague Wilsonova Bus Station  Economy $105
FlixBus 20h 30m 9:30 AM Rome Tiburtina Bus Station 6:00 AM Prague Wilsonova Bus Station  Economy $107
FlixBus 20h 45m 9:30 AM Rome Tiburtina Bus Station 6:15 AM Prague ÚAN Florenc  Economy $107
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $108
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $108

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 35m 5:00 PM Rome Tiburtina Bus Station 5:35 PM Prague Hradčanská  Economy $91
FlixBus 20h 45m 9:00 PM Rome Tiburtina Bus Station 5:45 PM Prague ÚAN Florenc  Economy $93
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $93
FlixBus 27h 0m 5:00 PM Rome Tiburtina Bus Station 8:00 PM Prague Wilsonova Bus Station  Economy $99
FlixBus 27h 5m 1:05 PM Rome Anagnina Bus Station 4:10 PM Prague Černý Most  Economy $100

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 55m 9:00 PM Rome Tiburtina Bus Station 10:55 PM Prague Na Knížecí Station  Economy $80
FlixBus 24h 35m 1:05 PM Rome Anagnina Bus Station 1:40 PM Prague Wilsonova Bus Station  Economy $85
FlixBus 24h 45m 1:05 PM Rome Anagnina Bus Station 1:50 PM Prague ÚAN Florenc  Economy $85
FlixBus 27h 0m 5:00 PM Rome Tiburtina Bus Station 8:00 PM Prague Wilsonova Bus Station  Economy $88
FlixBus 20h 30m 9:00 PM Rome Tiburtina Bus Station 5:30 PM Prague Wilsonova Bus Station  Economy $88

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
RegioJet 20h 10m 1:00 PM Rome Tiburtina Bus Station 9:10 AM Prague ÚAN Florenc  Economy $65
FlixBus 20h 35m 10:55 PM Rome Tiburtina Bus Station 7:30 PM Prague ÚAN Florenc  Economy $86
FlixBus 20h 25m 10:55 PM Rome Tiburtina Bus Station 7:20 PM Prague Wilsonova Bus Station  Economy $86
FlixBus 27h 25m 11:50 PM Rome Tiburtina Bus Station 3:15 AM Prague Wilsonova Bus Station  Economy $86
RegioJet 20h 39m 1:00 PM Rome Tiburtina Bus Station 9:39 AM Prague Wilsonova Bus Station  Economy $89

Best Price Offer: The price for the cheapest bus from Rome to Prague is $65 on 12/10/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Rome and Prague

See here how frequent the connections between Rome and Prague are, during different times and days of the week.
Saturday is the busiest day, with more than 47 daily buses from Rome to Prague. Tuesday has instead the fewest connections, with only 16 daily coaches between Rome and Prague.
The busiest time of the day is the Afternoon, with 118 buses from Rome to Prague, while Night sees the fewest connections between Rome and Prague, with 4 offers.

Facts about the bus from Rome to Prague

Compare all providers like FlixBus and RegioJet that travel 35 times every day by bus from Rome to Prague in one click! Book your bus ticket from Rome to Prague starting from $65!

Cheapest Bus $65
Fastest Bus 20h 10m
Earliest Bus 7:30 AM
Latest Bus 11:50 PM
Daily Bus Routes 35 Ø
Distance 572.5 miles
Bus Companies FlixBus and RegioJet

Cheapest bus connections from Rome to Prague

Every day, 35 buses from 2 bus companies leave Rome for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/30
Monday 12/01
Tuesday 12/02
Wednesday 12/03
Thursday 12/04
$125
Friday 12/05
$102
Saturday 12/06
$102
Sunday 12/07
$105
Monday 12/08
$91
Tuesday 12/09
$80
Wednesday 12/10
$86
Thursday 12/11
$87
Friday 12/12
$84
Saturday 12/13
$88
Sunday 12/14
$90
Monday 12/15
$86
Tuesday 12/16
$86
Wednesday 12/17
$88
Thursday 12/18
$98
Friday 12/19
$104
Saturday 12/20
$114
Sunday 12/21
$116
Monday 12/22
$118
Tuesday 12/23
$120
Wednesday 12/24
$123
Thursday 12/25
$118
Friday 12/26
$119
Saturday 12/27

The cheapest time to travel from Rome to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Prague, for the next 30 days.
With a price starting from $65, Wednesday is the cheapest day for a bus from Rome to Prague. Sunday instead is the most expensive day with prices starting from $90.
Afternoon is the cheapest day time for bus tickets from Rome to Prague, with $65. Morning is the most expensive time of the day with prices starting from $89.

How to save money travelling from Rome to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Rome to Prague are also emptier.

Beloved bus companies from Rome to Prague

These are the most booked bus companies between Rome to Prague from our users.

RegioJet from Rome to Prague

RegioJet

Here you will find the key facts about the RegioJet bus route Rome to Prague:

Cheapest Price $65
Fastest Bus 20h 10m
Earliest Bus 1:00 PM
Last Bus 1:00 PM
Daily Connections 2 Ø
Found on 12/2/2025

All bus stations and stops in Rome and Prague

In the map below, you can see where to find all bus stations in Rome and Prague.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Prague? Compare all modes of transports from Rome to Prague.

Service and Comfort on the bus from Rome to Prague

Want to know which seat classes are available on the buses from Rome to Prague? Or which bus companies serve the route Rome to Prague? Below you will find answers to your questions.

FAQs about the Rome to Prague bus

How much does a Rome Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $65 and takes 20h 10m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Rome to Prague?

This route is offered by 2 companies with a range of ticket prices between $65 and $202. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Rome to Prague each day?

Every day, the Rome to Prague bus route is served by approximately 35 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Rome to Prague take?

The fastest bus from Rome to Prague is offered by RegioJet and takes 20h 10m. Bus tickets for this connection cost $65. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Rome to Prague?

The earliest bus arriving in Prague from Rome starts at 7:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Rome to Prague?

The latest bus trip departing from Rome for Prague starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Rome Prague route?

When traveling by bus from Rome to Prague, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Rome and Prague?

You can check all the direct connections between Rome and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Rome to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Rome Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Prague on your planned travel date.

Available seat classes which are offered on the bus route Rome to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Prague

Here’s an overview of the most popular bus routes to Rome and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Amalfi to Rome Bus from Amalfi to Rome
From Assisi to Rome bus From Assisi to Rome bus
Bus Milan - Rome Bus Milan - Rome
Bus to Rome from Pisa Bus to Rome from Pisa
Bus Vienna to Prague Bus Vienna to Prague
Berlin to Prague bus Berlin to Prague bus
From Dresden to Prague bus From Dresden to Prague bus
Buses to Prague from Munich Buses to Prague from Munich
Popular Airport Shuttles to Rome and to Prague
CheckMyBus › Buses in Italy › Bus to Rome › Bus to Prague

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