Bus from Brussels to Prague from $43

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Compare all timetables for the bus from Brussels to Prague

Here is a selection of the cheapest bus trips from the schedule from Brussels to Prague from various bus operators like FlixBus or BlaBlaCar Bus for the next days.
today
from $70
tomorrow
from $50
Tuesday
from $43
Wednesday
from $45
Thursday
from $53
Friday
from $66
Saturday
from $68

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    15h 15m
    0
    9:25 PM
    Brussels
    North Station
    12:40 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $70
  • FlixBus
    16h 35m
    0
    9:25 PM
    Brussels
    North Station
    2:00 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $70
  • FlixBus
    18h 55m
    0
    3:45 PM
    Brussels
    Heysel
    10:40 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $70
  • BlaBlaCar Bus
    19h 55m
    0
    11:30 PM
    Brussels
    Midi Bus Station
    7:25 PM
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    $94
  • BlaBlaCar Bus
    19h 55m
    0
    11:30 PM
    Brussels
    Midi Bus Station
    7:25 PM
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    $94
  • Did you know that if you travel from Brussels to Prague via Maastricht, you can save more than $26? You can find the corresponding connections below.
    • FlixBus
      18h 45m
      0
      9:25 PM
      Brussels
      North Station
      11:00 PM
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      $9
      • Waiting Time 1h 55m
    • FlixBus
      15h 15m
      0
      12:55 AM
      Maastricht
      Meerssenerweg
      4:10 PM
      Prague
      Černý Most
      0
      FlixBus
      Economy
      $35
    Travel time is 3h 30m longer, but you will save $26

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    18h 35m
    0
    4:15 PM
    Brussels
    Midi Bus Station
    10:50 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $50
  • FlixBus
    16h 40m
    0
    4:15 PM
    Brussels
    Midi Bus Station
    8:55 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $50
  • FlixBus
    15h 0m
    0
    3:55 PM
    Brussels
    North Station
    6:55 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $50
  • BlaBlaCar Bus
    23h 15m
    0
    8:10 PM
    Brussels
    Midi Bus Station
    7:25 PM
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    $97
  • BlaBlaCar Bus
    23h 15m
    0
    8:10 PM
    Brussels
    Midi Bus Station
    7:25 PM
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    $97
  • Did you know that if you travel from Brussels to Prague via Maastricht, you can save more than $6? You can find the corresponding connections below.
    • FlixBus
      15h 45m
      0
      9:25 PM
      Brussels
      North Station
      11:00 PM
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      14h 5m
      0
      11:05 PM
      Maastricht
      Meerssenerweg
      1:10 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $35
    Travel time is 0h 45m longer, but you will save $6

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    18h 55m
    0
    11:45 AM
    Brussels
    North Station
    6:40 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $43
  • FlixBus
    15h 45m
    0
    9:25 PM
    Brussels
    North Station
    1:10 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $43
  • FlixBus
    16h 35m
    0
    9:25 PM
    Brussels
    North Station
    2:00 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    15h 0m
    0
    3:55 PM
    Brussels
    North Station
    6:55 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $45
  • FlixBus
    18h 55m
    0
    3:45 PM
    Brussels
    Heysel
    10:40 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $45

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    19h 15m
    0
    4:15 PM
    Brussels
    Midi Bus Station
    11:30 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $45
  • FlixBus
    18h 0m
    0
    10:10 PM
    Brussels
    Midi Bus Station
    4:10 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $45
  • FlixBus
    19h 40m
    0
    11:00 AM
    Brussels
    North Station
    6:40 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $46
  • FlixBus
    15h 15m
    0
    9:25 PM
    Brussels
    North Station
    12:40 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $46
  • FlixBus
    16h 5m
    0
    10:55 AM
    Brussels
    North Station
    3:00 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $46

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    13h 35m
    0
    10:30 AM
    Brussels
    North Station
    12:05 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    13h 55m
    0
    10:30 AM
    Brussels
    North Station
    12:25 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    16h 5m
    0
    10:55 AM
    Brussels
    North Station
    3:00 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    18h 45m
    0
    9:25 PM
    Brussels
    North Station
    4:10 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $53
  • FlixBus
    18h 0m
    0
    10:10 PM
    Brussels
    Midi Bus Station
    4:10 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $53
  • Did you know that if you travel from Brussels to Prague via Maastricht, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      15h 45m
      0
      9:25 PM
      Brussels
      North Station
      11:00 PM
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      14h 5m
      0
      11:05 PM
      Maastricht
      Meerssenerweg
      1:10 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $35
    Travel time is 2h 10m longer, but you will save $9

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    13h 55m
    0
    10:30 AM
    Brussels
    North Station
    12:25 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $66
  • FlixBus
    13h 35m
    0
    10:30 AM
    Brussels
    North Station
    12:05 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $66
  • FlixBus
    15h 0m
    0
    10:10 PM
    Brussels
    Midi Bus Station
    1:10 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $70
  • BlaBlaCar Bus
    19h 49m
    0
    3:11 AM
    Brussels
    Midi Bus Station
    11:00 PM
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    $92
  • BlaBlaCar Bus
    19h 49m
    0
    3:11 AM
    Brussels
    Midi Bus Station
    11:00 PM
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    $92
  • Did you know that if you travel from Brussels to Prague via Maastricht, you can save more than $22? You can find the corresponding connections below.
    • FlixBus
      15h 45m
      0
      9:25 PM
      Brussels
      North Station
      11:00 PM
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      14h 5m
      0
      11:05 PM
      Maastricht
      Meerssenerweg
      1:10 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $35
    Travel time is 2h 10m longer, but you will save $22

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    13h 35m
    0
    10:30 AM
    Brussels
    North Station
    12:05 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $68
  • FlixBus
    13h 55m
    0
    10:30 AM
    Brussels
    North Station
    12:25 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $68
  • FlixBus
    14h 40m
    0
    4:15 PM
    Brussels
    Midi Bus Station
    6:55 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $70
  • FlixBus
    15h 0m
    0
    10:10 PM
    Brussels
    Midi Bus Station
    1:10 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $70
  • FlixBus
    16h 40m
    0
    4:15 PM
    Brussels
    Midi Bus Station
    8:55 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $74
  • Did you know that if you travel from Brussels to Prague via Maastricht, you can save more than $24? You can find the corresponding connections below.
    • FlixBus
      15h 45m
      0
      9:25 PM
      Brussels
      North Station
      11:00 PM
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      $9
      • Waiting Time 0h 5m
    • FlixBus
      14h 5m
      0
      11:05 PM
      Maastricht
      Meerssenerweg
      1:10 PM
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      $35
    Travel time is 2h 10m longer, but you will save $24

Frequency of bus connections between Brussels and Prague

See here how frequent the connections between Brussels and Prague are, during different times and days of the week.
Sunday is the busiest day, with more than 41 daily buses from Brussels to Prague. Tuesday has instead the fewest connections, with only 27 daily coaches between Brussels and Prague.
The busiest time of the day is the Evening, with 90 buses from Brussels to Prague, while Morning sees the fewest connections between Brussels and Prague, with 40 offers.

Facts about the bus from Brussels to Prague

Compare all providers like FlixBus and BlaBlaCar Bus that travel 34 times every day by bus from Brussels to Prague in one click! Book your bus ticket from Brussels to Prague starting from $43!

Cheapest Bus $43
Fastest Bus 13h 35m
Earliest Bus 12:45 AM
Latest Bus 10:55 PM
Daily Bus Routes 34 Ø
Distance 446.6 miles
Bus Companies FlixBus and BlaBlaCar Bus

Cheapest bus connections from Brussels to Prague

Every day, 34 buses from 2 bus companies leave Brussels for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
$70
Monday 06/23
$50
Tuesday 06/24
$43
Wednesday 06/25
$45
Thursday 06/26
$53
Friday 06/27
$92
Saturday 06/28
$68
Sunday 06/29
$85
Monday 06/30
$59
Tuesday 07/01
$99
Wednesday 07/02
$56
Thursday 07/03
$66
Friday 07/04
$99
Saturday 07/05
$68
Sunday 07/06
$76
Monday 07/07
$62
Tuesday 07/08
$85
Wednesday 07/09
$59
Thursday 07/10
$59
Friday 07/11
$73
Saturday 07/12
$123
Sunday 07/13
$66
Monday 07/14
$56
Tuesday 07/15
$56
Wednesday 07/16
$60
Thursday 07/17
$62
Friday 07/18
$70
Saturday 07/19

The cheapest time to travel from Brussels to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Brussels to Prague, for the next 30 days.
With a price starting from $43, Tuesday is the cheapest day for a bus from Brussels to Prague. Sunday instead is the most expensive day with prices starting from $70.
Morning is the cheapest day time for bus tickets from Brussels to Prague, with $43. Night is the most expensive time of the day with prices starting from $47.

How to save money travelling from Brussels to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Brussels to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Brussels to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Brussels to Prague are also emptier.

Beloved bus companies from Brussels to Prague

These are the most booked bus companies between Brussels to Prague from our users.

FlixBus from Brussels to Prague

FlixBus

Here you will find the key facts about the FlixBus bus route Brussels to Prague:

Cheapest Price $43
Fastest Bus 13h 35m
Earliest Bus 12:45 AM
Last Bus 10:55 PM
Daily Connections 32 Ø
Found on 6/21/2025

All bus stations and stops in Brussels and Prague

In the map below, you can see where to find all bus stations in Brussels and Prague.

Service and Comfort on the bus from Brussels to Prague

Want to know which seat classes are available on the buses from Brussels to Prague? Or which bus companies serve the route Brussels to Prague? Below you will find answers to your questions.

FAQs about the Brussels to Prague bus

How much does a Brussels Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $43 and takes 18h 55m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Brussels to Prague?

This route is offered by 2 companies with a range of ticket prices between $43 and $230. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Brussels to Prague each day?

Every day, the Brussels to Prague bus route is served by approximately 34 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Brussels to Prague take?

The fastest bus from Brussels to Prague is offered by FlixBus and takes 13h 35m. Bus tickets for this connection cost $106. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Brussels to Prague?

The earliest bus arriving in Prague from Brussels starts at 12:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Brussels to Prague?

The latest bus trip departing from Brussels for Prague starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Brussels Prague route?

When traveling by bus from Brussels to Prague, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Brussels and Prague?

You can check all the direct connections between Brussels and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Brussels to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Brussels Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Brussels Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Brussels to Prague on your planned travel date.

Available seat classes which are offered on the bus route Brussels to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Brussels and to Prague

Here’s an overview of the most popular bus routes to Brussels and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
Berlin to Brussels bus Berlin to Brussels bus
From Charleroi to Brussels bus From Charleroi to Brussels bus
Buses from Dusseldorf to Brussels Buses from Dusseldorf to Brussels
Bus from Cologne to Brussels Bus from Cologne to Brussels
From Warsaw to Prague bus From Warsaw to Prague bus
Buses Pilsen - Prague Buses Pilsen - Prague
From London to Prague bus From London to Prague bus
Buses Salzburg - Prague Buses Salzburg - Prague
Popular Airport Shuttles to Brussels and to Prague
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