Bus from Milan to Brussels from $40

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Milan to Brussels

Here is a selection of the cheapest bus trips from the schedule from Milan to Brussels from various bus operators like FlixBus, BlaBlaCar Bus or European Sleeper for the next days.

today
$90
tomorrow
$63
Thursday
$55
Friday
$50
Saturday
$63
Sunday
$49
Monday
$56

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 15m 9:00 AM Milan San Donato Bus Station 8:15 AM Brussels Midi Bus Station  Economy $90
FlixBus 17h 30m 7:15 PM Milan Lampugnano Bus Station 12:45 PM Brussels Midi Bus Station  Economy $109
FlixBus 20h 35m 7:15 PM Milan Lampugnano Bus Station 3:50 PM Brussels Midi Bus Station  Economy $110
FlixBus 21h 30m 11:00 PM Milan Lampugnano Bus Station 8:30 PM Brussels North Station  Economy $110
FlixBus 19h 50m 11:30 AM Milan Lampugnano Bus Station 7:20 AM Brussels Midi Bus Station  Economy $121
  • Did you know that if you travel from Milan to Brussels via Basel, you can save more than $30? You can find the corresponding connections below.
    • FlixBus
      15h 20m
      0
      5:20 PM
      Milan
      Lampugnano Bus Station
      10:55 PM
      Basel
      Central Station
      0
      FlixBus
      Economy
      $24
      • Waiting Time 1h 30m
    • FlixBus
      8h 15m
      0
      12:25 AM
      Basel
      Central Station
      8:40 AM
      Brussels
      North Station
      0
      FlixBus
      Economy
      $36
    Travel Time is 2h 10m shorter, and you will save $30

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 0m 7:40 PM Milan Lampugnano Bus Station 8:40 AM Brussels North Station  Economy $63
FlixBus 20h 35m 2:40 PM Milan San Donato Bus Station 11:15 AM Brussels North Station  Economy $82
FlixBus 21h 40m 2:40 PM Milan San Donato Bus Station 12:20 PM Brussels Midi Bus Station  Economy $82
European Sleeper 19h 57m 3:45 PM Milan Porta Garibaldi Train Station 11:42 AM Brussels Midi Bus Station  Economy $195
  • Did you know that if you travel from Milan to Brussels via Metz, you can save more than $18? You can find the corresponding connections below.
    • FlixBus
      18h 55m
      0
      9:45 PM
      Milan
      Lampugnano Bus Station
      6:50 AM
      Metz
      Bus Station
      0
      FlixBus
      Economy
      $34
      • Waiting Time 5h 15m
    • FlixBus
      4h 35m
      0
      12:05 PM
      Metz
      Bus Station
      4:40 PM
      Brussels
      North Station
      0
      FlixBus
      Economy
      $11
    Travel time is 5h 55m longer, but you will save $18

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 18h 30m 5:30 PM Milan Lampugnano Bus Station 12:00 PM Brussels Midi Bus Station  Economy $55
BlaBlaCar Bus 17h 35m 11:55 PM Milan Lampugnano Bus Station 5:30 PM Brussels Midi Bus Station  Economy $56
BlaBlaCar Bus 17h 40m 10:20 AM Milan Lampugnano Bus Station 4:00 AM Brussels North Station  Economy $67
FlixBus 13h 0m 7:40 PM Milan Lampugnano Bus Station 8:40 AM Brussels North Station  Economy $77
FlixBus 18h 30m 12:15 PM Milan Lampugnano Bus Station 6:45 AM Brussels North Station  Economy $94
  • Did you know that if you travel from Milan to Brussels via Metz, you can save more than $10? You can find the corresponding connections below.
    • FlixBus
      18h 55m
      0
      9:45 PM
      Milan
      Lampugnano Bus Station
      6:50 AM
      Metz
      Bus Station
      0
      FlixBus
      Economy
      $34
      • Waiting Time 5h 15m
    • FlixBus
      4h 35m
      0
      12:05 PM
      Metz
      Bus Station
      4:40 PM
      Brussels
      North Station
      0
      FlixBus
      Economy
      $11
    Travel time is 5h 55m longer, but you will save $10

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 17h 35m 11:55 PM Milan Lampugnano Bus Station 5:30 PM Brussels Midi Bus Station  Economy $50
BlaBlaCar Bus 13h 35m 3:20 PM Milan Lampugnano Bus Station 4:55 AM Brussels Midi Bus Station  Economy $78
FlixBus 12h 50m 10:45 PM Milan Lampugnano Bus Station 11:35 AM Brussels North Station  Economy $82
FlixBus 13h 0m 7:40 PM Milan Lampugnano Bus Station 8:40 AM Brussels North Station  Economy $84
European Sleeper 19h 44m 3:45 PM Milan Porta Garibaldi Train Station 11:29 AM Brussels Midi Bus Station  Economy $217
  • Did you know that if you travel from Milan to Brussels via Metz, you can save more than $6? You can find the corresponding connections below.
    • BlaBlaCar Bus
      12h 45m
      0
      7:55 PM
      Milan
      Lampugnano Bus Station
      4:45 AM
      Metz
      Bus Station
      0
      BlaBlaCar Bus
      Economy
      $33
      • Waiting Time 0h 15m
    • BlaBlaCar Bus
      3h 40m
      0
      5:00 AM
      Metz
      Bus Station
      8:40 AM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $11
    Travel Time is 0h 5m shorter, and you will save $6

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 17h 40m 10:20 AM Milan Lampugnano Bus Station 4:00 AM Brussels North Station  Economy $63
BlaBlaCar Bus 13h 35m 3:20 PM Milan Lampugnano Bus Station 4:55 AM Brussels Midi Bus Station  Economy $67
BlaBlaCar Bus 12h 45m 7:55 PM Milan Lampugnano Bus Station 8:40 AM Brussels Midi Bus Station  Economy $67
FlixBus 13h 0m 7:40 PM Milan Lampugnano Bus Station 8:40 AM Brussels North Station  Economy $70
FlixBus 12h 50m 10:45 PM Milan Lampugnano Bus Station 11:35 AM Brussels North Station  Economy $73
  • Did you know that if you travel from Milan to Brussels via Metz, you can save more than $19? You can find the corresponding connections below.
    • BlaBlaCar Bus
      12h 45m
      0
      7:55 PM
      Milan
      Lampugnano Bus Station
      4:45 AM
      Metz
      Bus Station
      0
      BlaBlaCar Bus
      Economy
      $33
      • Waiting Time 0h 15m
    • BlaBlaCar Bus
      3h 40m
      0
      5:00 AM
      Metz
      Bus Station
      8:40 AM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $11
    Travel time is the same as the direct connection, but you will save $19

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 17h 35m 11:55 PM Milan Lampugnano Bus Station 5:30 PM Brussels Midi Bus Station  Economy $49
BlaBlaCar Bus 17h 40m 10:20 AM Milan Lampugnano Bus Station 4:00 AM Brussels North Station  Economy $78
FlixBus 18h 30m 12:15 PM Milan Lampugnano Bus Station 6:45 AM Brussels North Station  Economy $101
FlixBus 13h 0m 7:40 PM Milan Lampugnano Bus Station 8:40 AM Brussels North Station  Economy $101
European Sleeper 20h 10m 3:18 PM Milan Porta Garibaldi Train Station 11:28 AM Brussels Midi Bus Station  Economy $217
  • Did you know that if you travel from Milan to Brussels via Metz, you can save more than $5? You can find the corresponding connections below.
    • BlaBlaCar Bus
      12h 45m
      0
      7:55 PM
      Milan
      Lampugnano Bus Station
      4:45 AM
      Metz
      Bus Station
      0
      BlaBlaCar Bus
      Economy
      $33
      • Waiting Time 0h 15m
    • BlaBlaCar Bus
      3h 40m
      0
      5:00 AM
      Metz
      Bus Station
      8:40 AM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $11
    Travel Time is 0h 15m shorter, and you will save $5

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 13h 35m 3:20 PM Milan Lampugnano Bus Station 4:55 AM Brussels Midi Bus Station  Economy $56
BlaBlaCar Bus 12h 45m 7:55 PM Milan Lampugnano Bus Station 8:40 AM Brussels Midi Bus Station  Economy $56
FlixBus 13h 0m 7:40 PM Milan Lampugnano Bus Station 8:40 AM Brussels North Station  Economy $57
FlixBus 12h 50m 10:45 PM Milan Lampugnano Bus Station 11:35 AM Brussels North Station  Economy $57
FlixBus 18h 35m 8:30 AM Milan Lampugnano Bus Station 3:05 AM Brussels Midi Bus Station  Economy $95
  • Did you know that if you travel from Milan to Brussels via Metz, you can save more than $12? You can find the corresponding connections below.
    • BlaBlaCar Bus
      12h 45m
      0
      7:55 PM
      Milan
      Lampugnano Bus Station
      4:45 AM
      Metz
      Bus Station
      0
      BlaBlaCar Bus
      Economy
      $33
      • Waiting Time 0h 15m
    • BlaBlaCar Bus
      3h 40m
      0
      5:00 AM
      Metz
      Bus Station
      8:40 AM
      Brussels
      Midi Bus Station
      0
      BlaBlaCar Bus
      Economy
      $11
    Travel time is the same as the direct connection, but you will save $12

Best Price Offer: The price for the cheapest bus from Milan to Brussels is $40 on 11/20/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Milan and Brussels

See here how frequent the connections between Milan and Brussels are, during different times and days of the week.
Sunday is the busiest day, with more than 15 daily buses from Milan to Brussels. Monday has instead the fewest connections, with only 7 daily coaches between Milan and Brussels.
The busiest time of the day is the Evening, with 34 buses from Milan to Brussels, while Night sees the fewest connections between Milan and Brussels, with 4 offers.

Facts about the bus from Milan to Brussels

Compare all providers like FlixBus, BlaBlaCar Bus and European Sleeper that travel 10 times every day by bus from Milan to Brussels in one click! Book your bus ticket from Milan to Brussels starting from $40!

Cheapest Bus $40
Fastest Bus 12h 45m
Earliest Bus 9:00 AM
Latest Bus 10:45 PM
Daily Bus Routes 10 Ø
Distance 433.6 miles
Bus Companies FlixBus, BlaBlaCar Bus and European Sleeper

Cheapest bus connections from Milan to Brussels

Every day, 10 buses from 3 bus companies leave Milan for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/03/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 11/01
Monday 11/02
Tuesday 11/03
$109
Wednesday 11/04
$63
Thursday 11/05
$55
Friday 11/06
$50
Saturday 11/07
$63
Sunday 11/08
$49
Monday 11/09
$56
Tuesday 11/10
$91
Wednesday 11/11
$46
Thursday 11/12
$53
Friday 11/13
$45
Saturday 11/14
$43
Sunday 11/15
$44
Monday 11/16
$45
Tuesday 11/17
$60
Wednesday 11/18
$46
Thursday 11/19
$44
Friday 11/20
$40
Saturday 11/21
$40
Sunday 11/22
$46
Monday 11/23
$45
Tuesday 11/24
$57
Wednesday 11/25
$46
Thursday 11/26
$40
Friday 11/27
$46
Saturday 11/28

The cheapest time to travel from Milan to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Brussels, for the next 30 days.
With a price starting from $40, Sunday is the cheapest day for a bus from Milan to Brussels. Tuesday instead is the most expensive day with prices starting from $57.
Night is the cheapest day time for bus tickets from Milan to Brussels, with $40. Morning is the most expensive time of the day with prices starting from $63.

How to save money travelling from Milan to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Brussels are also emptier.

Beloved bus companies from Milan to Brussels

These are the most booked bus companies between Milan to Brussels from our users.

FlixBus from Milan to Brussels

FlixBus

Here you will find the key facts about the FlixBus bus route Milan to Brussels:

Cheapest Price $57
Fastest Bus 12h 50m
Earliest Bus 9:00 AM
Last Bus 10:45 PM
Daily Connections 7 Ø
Found on 11/3/2026

BlaBlaCar Bus from Milan to Brussels

BlaBlaCar Bus

Here you will find the key facts about the BlaBlaCar Bus bus route Milan to Brussels:

Cheapest Price $49
Fastest Bus 12h 45m
Earliest Bus 10:20 AM
Last Bus 7:55 PM
Daily Connections 3 Ø
Found on 11/3/2026

All bus stations and stops in Milan and Brussels

In the map below, you can see where to find all bus stations in Milan and Brussels.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Brussels? Compare all modes of transports from Milan to Brussels.

Service and Comfort on the bus from Milan to Brussels

Want to know which seat classes are available on the buses from Milan to Brussels? Or which bus companies serve the route Milan to Brussels? Below you will find answers to your questions.

FAQs about the Milan to Brussels bus

How much does a Milan Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $40 and takes 17h 35m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Milan to Brussels?

This route is offered by 3 companies with a range of ticket prices between $40 and $217. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Milan to Brussels each day?

Every day, the Milan to Brussels bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Brussels take?

The fastest bus from Milan to Brussels is offered by BlaBlaCar Bus and takes 12h 45m. Bus tickets for this connection cost $78. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Brussels?

The earliest bus arriving in Brussels from Milan starts at 9:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Brussels?

The latest bus trip departing from Milan for Brussels starts at 10:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Brussels route?

When traveling by bus from Milan to Brussels, passengers can travel with FlixBus, BlaBlaCar Bus and European Sleeper. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Brussels?

You can check all the direct connections between Milan and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, BlaBlaCar Bus and European Sleeper.

What can I take with me on the Milan to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Milan to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 10 daily trips between Milan and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Milan to Brussels?

Prices and availability for 10 trips between Milan and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Milan to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Brussels

Here’s an overview of the most popular bus routes to Milan and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Siena - Milan Bus Siena - Milan
Buses to Milan from Matera Buses to Milan from Matera
Buses Savona to Milan Buses Savona to Milan
From Catania to Milan bus From Catania to Milan bus
Dijon to Brussels bus Dijon to Brussels bus
Bus to Brussels from Novi Sad Bus to Brussels from Novi Sad
Bus to Brussels from Toulouse Bus to Brussels from Toulouse
Bus to Brussels from Ljubljana Bus to Brussels from Ljubljana
Popular Airport Shuttles to Milan and to Brussels
CheckMyBus › Buses in Italy › Bus to Milan › Bus to Brussels

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.