Bus from Lyon to Brussels from $23

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Compare all timetables for the bus from Lyon to Brussels

Here is a selection of the cheapest bus trips from the schedule from Lyon to Brussels from various bus operators like FlixBus or BlaBlaCar Bus for the next days.
today
from $28
tomorrow
from $43
Thursday
from $23
Friday
from $36
Saturday
from $32
Sunday
from $30
Monday
from $32

Cheapest bus trips today

Prices are for one way and one person
  • BlaBlaCar Bus
    13h 55m
    0
    3:35 AM
    Lyon
    Perrache Train Station
    5:30 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $28
  • BlaBlaCar Bus
    10h 40m
    0
    1:20 AM
    Lyon
    Perrache Train Station
    12:00 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $32
  • BlaBlaCar Bus
    12h 0m
    0
    7:35 AM
    Lyon
    Perrache Train Station
    7:35 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $43
  • FlixBus
    13h 40m
    0
    9:30 PM
    Lyon
    Perrache Bus Stop
    11:10 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $46
  • FlixBus
    11h 30m
    0
    2:30 AM
    Lyon
    Perrache Bus Stop
    2:00 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $52

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    13h 40m
    0
    9:30 PM
    Lyon
    Perrache Bus Stop
    11:10 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $43
  • FlixBus
    11h 45m
    0
    7:00 PM
    Lyon
    Perrache Bus Stop
    6:45 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $45
  • FlixBus
    12h 55m
    0
    5:00 AM
    Lyon
    Perrache Bus Stop
    5:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $52
  • FlixBus
    11h 50m
    0
    8:40 AM
    Lyon
    Perrache Bus Stop
    8:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $54
  • FlixBus
    11h 30m
    0
    12:50 AM
    Lyon
    Perrache Bus Stop
    12:20 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $56
  • Did you know that if you travel from Lyon to Brussels via Nancy, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      13h 40m
      0
      7:00 PM
      Lyon
      Perrache Bus Stop
      12:35 AM
      Nancy
      St. Catherine Bus Stop
      0
      FlixBus
      Economy
      $19
      • Waiting Time 3h 5m
    • FlixBus
      5h 0m
      0
      3:40 AM
      Nancy
      St. Catherine Bus Stop
      8:40 AM
      Brussels
      North Station
      0
      FlixBus
      Economy
      $15
    Travel time is 2h 10m longer, but you will save $9

Cheapest bus trips Thursday

Prices are for one way and one person
  • BlaBlaCar Bus
    11h 50m
    0
    6:20 AM
    Lyon
    Perrache Train Station
    6:10 PM
    Brussels
    North Station
    0
    BlaBlaCar Bus
    Economy
    $23
  • BlaBlaCar Bus
    12h 10m
    0
    2:45 AM
    Lyon
    Perrache Train Station
    2:55 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $24
  • BlaBlaCar Bus
    11h 40m
    0
    10:50 AM
    Lyon
    Perrache Train Station
    10:30 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $24
  • FlixBus
    11h 0m
    0
    12:15 AM
    Lyon
    Perrache Bus Stop
    11:15 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $44
  • FlixBus
    11h 50m
    0
    8:40 AM
    Lyon
    Perrache Bus Stop
    8:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $44

Cheapest bus trips Friday

Prices are for one way and one person
  • BlaBlaCar Bus
    9h 40m
    0
    1:00 AM
    Lyon
    Perrache Train Station
    10:40 AM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $36
  • BlaBlaCar Bus
    10h 25m
    0
    1:35 AM
    Lyon
    Perrache Train Station
    12:00 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $37
  • BlaBlaCar Bus
    12h 0m
    0
    2:45 AM
    Lyon
    Perrache Train Station
    2:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $38
  • FlixBus
    12h 30m
    0
    5:25 AM
    Lyon
    Perrache Bus Stop
    5:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $59
  • FlixBus
    11h 0m
    0
    12:15 AM
    Lyon
    Perrache Bus Stop
    11:15 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62

Cheapest bus trips Saturday

Prices are for one way and one person
  • BlaBlaCar Bus
    11h 40m
    0
    10:50 AM
    Lyon
    Perrache Train Station
    10:30 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $32
  • BlaBlaCar Bus
    11h 35m
    0
    12:00 PM
    Lyon
    Perrache Train Station
    11:35 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $32
  • BlaBlaCar Bus
    9h 40m
    0
    8:40 PM
    Lyon
    Perrache Train Station
    6:20 AM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $42
  • FlixBus
    11h 45m
    0
    3:15 PM
    Lyon
    Perrache Bus Stop
    3:00 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $43
  • FlixBus
    11h 45m
    0
    7:00 PM
    Lyon
    Perrache Bus Stop
    6:45 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $45

Cheapest bus trips Sunday

Prices are for one way and one person
  • BlaBlaCar Bus
    12h 0m
    0
    2:45 AM
    Lyon
    Perrache Train Station
    2:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $30
  • BlaBlaCar Bus
    10h 25m
    0
    1:35 AM
    Lyon
    Perrache Train Station
    12:00 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $32
  • BlaBlaCar Bus
    9h 40m
    0
    1:00 AM
    Lyon
    Perrache Train Station
    10:40 AM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $36
  • FlixBus
    11h 0m
    0
    12:15 AM
    Lyon
    Perrache Bus Stop
    11:15 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $57
  • FlixBus
    11h 30m
    0
    2:30 AM
    Lyon
    Perrache Bus Stop
    2:00 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $57

Cheapest bus trips Monday

Prices are for one way and one person
  • BlaBlaCar Bus
    10h 25m
    0
    1:35 AM
    Lyon
    Perrache Train Station
    12:00 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $32
  • BlaBlaCar Bus
    12h 0m
    0
    2:45 AM
    Lyon
    Perrache Train Station
    2:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $32
  • BlaBlaCar Bus
    11h 45m
    0
    8:00 AM
    Lyon
    Perrache Train Station
    7:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $32
  • FlixBus
    13h 25m
    0
    9:30 PM
    Lyon
    Perrache Bus Stop
    10:55 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $38
  • FlixBus
    11h 10m
    0
    2:30 AM
    Lyon
    Perrache Bus Stop
    1:40 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $39

Frequency of bus connections between Lyon and Brussels

See here how frequent the connections between Lyon and Brussels are, during different times and days of the week.
Friday is the busiest day, with more than 28 daily buses from Lyon to Brussels. Wednesday has instead the fewest connections, with only 11 daily coaches between Lyon and Brussels.
The busiest time of the day is the Night, with 66 buses from Lyon to Brussels, while Afternoon sees the fewest connections between Lyon and Brussels, with 17 offers.

Facts about the bus from Lyon to Brussels

Compare all providers like FlixBus and BlaBlaCar Bus that travel 20 times every day by bus from Lyon to Brussels in one click! Book your bus ticket from Lyon to Brussels starting from $23!

Cheapest Bus $23
Fastest Bus 9h 40m
Earliest Bus 12:15 AM
Latest Bus 11:40 PM
Daily Bus Routes 20 Ø
Distance 352.7 miles
Bus Companies FlixBus and BlaBlaCar Bus

Cheapest bus connections from Lyon to Brussels

Every day, 20 buses from 2 bus companies leave Lyon for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/13/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
$28
Wednesday 05/14
$43
Thursday 05/15
$24
Friday 05/16
$36
Saturday 05/17
$32
Sunday 05/18
$30
Monday 05/19
$32
Tuesday 05/20
$29
Wednesday 05/21
$38
Thursday 05/22
$26
Friday 05/23
$49
Saturday 05/24
$32
Sunday 05/25
$36
Monday 05/26
$52
Tuesday 05/27
$36
Wednesday 05/28
$84
Thursday 05/29
$64
Friday 05/30
$67
Saturday 05/31
$61
Sunday 06/01
$72
Monday 06/02
$45
Tuesday 06/03
$27
Wednesday 06/04
$39
Thursday 06/05
$28
Friday 06/06
$51
Saturday 06/07

The cheapest time to travel from Lyon to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Brussels, for the next 30 days.
With a price starting from $23, Thursday is the cheapest day for a bus from Lyon to Brussels. Wednesday instead is the most expensive day with prices starting from $43.
Morning is the cheapest day time for bus tickets from Lyon to Brussels, with $23. Evening is the most expensive time of the day with prices starting from $38.

How to save money travelling from Lyon to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lyon to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Brussels are also emptier.

Beloved bus companies from Lyon to Brussels

These are the most booked bus companies between Lyon to Brussels from our users.

FlixBus from Lyon to Brussels

FlixBus

Here you will find the key facts about the FlixBus bus route Lyon to Brussels:

Cheapest Price $38
Fastest Bus 10h 40m
Earliest Bus 12:15 AM
Last Bus 11:40 PM
Daily Connections 15 Ø
Found on 5/13/2025

BlaBlaCar Bus from Lyon to Brussels

BlaBlaCar Bus

Here you will find the key facts about the BlaBlaCar Bus bus route Lyon to Brussels:

Cheapest Price $23
Fastest Bus 9h 40m
Earliest Bus 1:20 AM
Last Bus 8:40 PM
Daily Connections 6 Ø
Found on 5/13/2025

All bus stations and stops in Lyon and Brussels

In the map below, you can see where to find all bus stations in Lyon and Brussels.

Service and Comfort on the bus from Lyon to Brussels

Want to know which seat classes are available on the buses from Lyon to Brussels? Or which bus companies serve the route Lyon to Brussels? Below you will find answers to your questions.

FAQs about the Lyon to Brussels bus

How much does a Lyon Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $23 and takes 11h 50m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Lyon to Brussels?

This route is offered by 2 companies with a range of ticket prices between $23 and $104. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Lyon to Brussels each day?

Every day, the Lyon to Brussels bus route is served by approximately 20 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lyon to Brussels take?

The fastest bus from Lyon to Brussels is offered by BlaBlaCar Bus and takes 9h 40m. Bus tickets for this connection cost $36. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lyon to Brussels?

The earliest bus arriving in Brussels from Lyon starts at 12:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lyon to Brussels?

The latest bus trip departing from Lyon for Brussels starts at 11:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lyon Brussels route?

When traveling by bus from Lyon to Brussels, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lyon and Brussels?

You can check all the direct connections between Lyon and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Lyon to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lyon Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Lyon to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lyon and to Brussels

Here’s an overview of the most popular bus routes to Lyon and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Lille to Lyon Bus Lille to Lyon
From Perpignan to Lyon bus From Perpignan to Lyon bus
Bus from Val-d'Isère to Lyon Bus from Val-d'Isère to Lyon
Buses Tignes to Lyon Buses Tignes to Lyon
Buses to Brussels from Liege Buses to Brussels from Liege
Bus from Milan to Brussels Bus from Milan to Brussels
Bus from Paris to Brussels Bus from Paris to Brussels
Buses from London to Brussels Buses from London to Brussels
Popular Airport Shuttles to Lyon and to Brussels
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