Bus from Lyon to Brussels from $28

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Compare all timetables for the bus from Lyon to Brussels

Here is a selection of the cheapest bus trips from the schedule from Lyon to Brussels from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today
$52
tomorrow
$45
Monday
$49
Tuesday
$45
Wednesday
$44
Thursday
$33
Friday
$41

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 11h 25m 8:30 AM Lyon Perrache Train Station 7:55 PM Brussels North Station  Economy $52
FlixBus 11h 50m 6:55 PM Lyon Lyon Avenue Tony Garnier Bus Stop 6:45 AM Brussels North Station  Economy $54
FlixBus 14h 15m 2:25 AM Lyon Lyon Avenue Tony Garnier Bus Stop 4:40 PM Brussels North Station  Economy $56
BlaBlaCar Bus 13h 5m 2:00 PM Lyon Perrache Train Station 3:05 AM Brussels Midi Bus Station  Economy $64
BlaBlaCar Bus 10h 40m 5:20 PM Lyon Perrache Train Station 4:00 AM Brussels North Station  Economy $64

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 10h 30m 1:30 AM Lyon Perrache Train Station 12:00 PM Brussels Midi Bus Station  Economy $45
BlaBlaCar Bus 11h 0m 2:30 AM Lyon Perrache Train Station 1:30 PM Brussels Midi Bus Station  Economy $45
BlaBlaCar Bus 10h 15m 6:15 AM Lyon Perrache Train Station 4:30 PM Brussels Midi Bus Station  Economy $52
FlixBus 11h 50m 6:55 PM Lyon Lyon Avenue Tony Garnier Bus Stop 6:45 AM Brussels North Station  Economy $76
FlixBus 14h 15m 2:25 AM Lyon Lyon Avenue Tony Garnier Bus Stop 4:40 PM Brussels North Station  Economy $84

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 15m 2:25 AM Lyon Lyon Avenue Tony Garnier Bus Stop 4:40 PM Brussels North Station  Economy $49
FlixBus 15h 15m 5:20 AM Lyon Lyon Avenue Tony Garnier Bus Stop 8:35 PM Brussels North Station  Economy $51
BlaBlaCar Bus 11h 25m 8:30 AM Lyon Perrache Train Station 7:55 PM Brussels North Station  Economy $52
FlixBus 12h 35m 11:35 PM Lyon Lyon Avenue Tony Garnier Bus Stop 12:10 PM Brussels North Station  Economy $72
BlaBlaCar Bus 10h 50m 9:10 PM Lyon Perrache Train Station 8:00 AM Brussels Midi Bus Station  Economy $82
  • Did you know that if you travel from Lyon to Brussels via Dijon, you can save more than $7? You can find the corresponding connections below.
    • FlixBus
      14h 20m
      0
      6:25 PM
      Lyon
      Lyon Avenue Tony Garnier Bus Stop
      9:00 PM
      Dijon
      Central Bus Station
      0
      FlixBus
      Economy
      $10
      • Waiting Time 0h 45m
    • FlixBus
      11h 0m
      0
      9:45 PM
      Dijon
      Central Bus Station
      8:45 AM
      Brussels
      North Station
      0
      FlixBus
      Economy
      $32
    Travel time is 3h 30m longer, but you will save $7

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 15h 15m 5:20 AM Lyon Lyon Avenue Tony Garnier Bus Stop 8:35 PM Brussels North Station  Economy $45
FlixBus 12h 35m 11:35 PM Lyon Lyon Avenue Tony Garnier Bus Stop 12:10 PM Brussels North Station  Economy $52
FlixBus 13h 45m 9:25 PM Lyon Lyon Avenue Tony Garnier Bus Stop 11:10 AM Brussels North Station  Economy $59
FlixBus 10h 50m 9:25 PM Lyon Lyon Avenue Tony Garnier Bus Stop 8:15 AM Brussels Midi Bus Station  Economy $72
FlixBus 12h 5m 4:40 PM Lyon Lyon Avenue Tony Garnier Bus Stop 4:45 AM Brussels North Station  Economy $82

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 10m 1:40 AM Lyon Lyon Avenue Tony Garnier Bus Stop 3:50 PM Brussels Midi Bus Station  Economy $44
FlixBus 11h 50m 6:55 PM Lyon Lyon Avenue Tony Garnier Bus Stop 6:45 AM Brussels North Station  Economy $47
FlixBus 15h 15m 10:15 PM Lyon Lyon Avenue Tony Garnier Bus Stop 1:30 PM Brussels North Station  Economy $53
BlaBlaCar Bus 11h 25m 8:30 AM Lyon Perrache Train Station 7:55 PM Brussels North Station  Economy $58
BlaBlaCar Bus 11h 5m 12:55 AM Lyon Perrache Train Station 12:00 PM Brussels Midi Bus Station  Economy $73

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 11h 15m 6:15 AM Lyon Perrache Train Station 5:30 PM Brussels Midi Bus Station  Economy $33
BlaBlaCar Bus 11h 50m 10:40 AM Lyon Perrache Train Station 10:30 PM Brussels Midi Bus Station  Economy $33
BlaBlaCar Bus 10h 40m 8:30 AM Lyon Perrache Train Station 7:10 PM Brussels Midi Bus Station  Economy $35
FlixBus 11h 50m 3:15 PM Lyon Lyon Avenue Tony Garnier Bus Stop 3:05 AM Brussels Midi Bus Station  Economy $41
FlixBus 12h 5m 4:40 PM Lyon Lyon Avenue Tony Garnier Bus Stop 4:45 AM Brussels North Station  Economy $42

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
BlaBlaCar Bus 10h 30m 1:30 AM Lyon Perrache Train Station 12:00 PM Brussels Midi Bus Station  Economy $41
BlaBlaCar Bus 11h 0m 2:30 AM Lyon Perrache Train Station 1:30 PM Brussels Midi Bus Station  Economy $43
BlaBlaCar Bus 10h 15m 6:15 AM Lyon Perrache Train Station 4:30 PM Brussels Midi Bus Station  Economy $43
FlixBus 11h 50m 6:55 PM Lyon Lyon Avenue Tony Garnier Bus Stop 6:45 AM Brussels North Station  Economy $56
FlixBus 12h 50m 3:15 PM Lyon Lyon Avenue Tony Garnier Bus Stop 4:05 AM Brussels North Station  Economy $62

Best Price Offer: The price for the cheapest bus from Lyon to Brussels is $28 on 6/29/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Lyon and Brussels

See here how frequent the connections between Lyon and Brussels are, during different times and days of the week.
Sunday is the busiest day, with more than 30 daily buses from Lyon to Brussels. Tuesday has instead the fewest connections, with only 12 daily coaches between Lyon and Brussels.
The busiest time of the day is the Night, with 59 buses from Lyon to Brussels, while Evening sees the fewest connections between Lyon and Brussels, with 30 offers.

Facts about the bus from Lyon to Brussels

Compare all providers like FlixBus and BlaBlaCar Bus that travel 21 times every day by bus from Lyon to Brussels in one click! Book your bus ticket from Lyon to Brussels starting from $28!

Cheapest Bus $28
Fastest Bus 10h 15m
Earliest Bus 12:10 AM
Latest Bus 11:35 PM
Daily Bus Routes 21 Ø
Distance 352.7 miles
Bus Companies FlixBus and BlaBlaCar Bus

Cheapest bus connections from Lyon to Brussels

Every day, 21 buses from 2 bus companies leave Lyon for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/14
Monday 06/15
Tuesday 06/16
Wednesday 06/17
Thursday 06/18
Friday 06/19
Saturday 06/20
$54
Sunday 06/21
$45
Monday 06/22
$52
Tuesday 06/23
$45
Wednesday 06/24
$44
Thursday 06/25
$41
Friday 06/26
$41
Saturday 06/27
$33
Sunday 06/28
$37
Monday 06/29
$28
Tuesday 06/30
$40
Wednesday 07/01
$35
Thursday 07/02
$30
Friday 07/03
$35
Saturday 07/04
$37
Sunday 07/05
$35
Monday 07/06
$33
Tuesday 07/07
$28
Wednesday 07/08
$33
Thursday 07/09
$30
Friday 07/10
$36
Saturday 07/11

The cheapest time to travel from Lyon to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Brussels, for the next 30 days.
With a price starting from $28, Monday is the cheapest day for a bus from Lyon to Brussels. Sunday instead is the most expensive day with prices starting from $35.
Night is the cheapest day time for bus tickets from Lyon to Brussels, with $28. Evening is the most expensive time of the day with prices starting from $46.

How to save money travelling from Lyon to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Lyon to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Lyon to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Lyon to Brussels are also emptier.

Beloved bus companies from Lyon to Brussels

These are the most booked bus companies between Lyon to Brussels from our users.

BlaBlaCar Bus from Lyon to Brussels

BlaBlaCar Bus

Here you will find the key facts about the BlaBlaCar Bus bus route Lyon to Brussels:

Cheapest Price $33
Fastest Bus 10h 15m
Earliest Bus 1:30 AM
Last Bus 9:10 PM
Daily Connections 7 Ø
Found on 6/19/2026

All bus stations and stops in Lyon and Brussels

In the map below, you can see where to find all bus stations in Lyon and Brussels.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Lyon to Brussels? Compare all modes of transports from Lyon to Brussels.

Service and Comfort on the bus from Lyon to Brussels

Want to know which seat classes are available on the buses from Lyon to Brussels? Or which bus companies serve the route Lyon to Brussels? Below you will find answers to your questions.

FAQs about the Lyon to Brussels bus

How much does a Lyon Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $28 and takes 11h 15m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Lyon to Brussels?

This route is offered by 2 companies with a range of ticket prices between $28 and $151. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Lyon to Brussels each day?

Every day, the Lyon to Brussels bus route is served by approximately 21 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Lyon to Brussels take?

The fastest bus from Lyon to Brussels is offered by BlaBlaCar Bus and takes 10h 15m. Bus tickets for this connection cost $52. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Lyon to Brussels?

The earliest bus arriving in Brussels from Lyon starts at 12:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Lyon to Brussels?

The latest bus trip departing from Lyon for Brussels starts at 11:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Lyon Brussels route?

When traveling by bus from Lyon to Brussels, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Lyon and Brussels?

You can check all the direct connections between Lyon and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Lyon to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Lyon Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Lyon to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 21 daily trips between Lyon and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lyon to Brussels?

Prices and availability for 21 trips between Lyon and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lyon to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lyon and to Brussels

Here’s an overview of the most popular bus routes to Lyon and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Venice to Lyon Bus from Venice to Lyon
Buses Saint-Étienne to Lyon Buses Saint-Étienne to Lyon
From Bilbao to Lyon bus From Bilbao to Lyon bus
Bus Florence to Lyon Bus Florence to Lyon
Bus Charleville-Mézières to Brussels Bus Charleville-Mézières to Brussels
Buses from Aveiro to Brussels Buses from Aveiro to Brussels
Lucerne to Brussels bus Lucerne to Brussels bus
Buses from Bern to Brussels Buses from Bern to Brussels
Popular Airport Shuttles to Lyon and to Brussels
CheckMyBus › Buses in France › Bus to Lyon › Bus to Brussels

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