Compare all timetables for the bus from Prague to Lyon
Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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BlaBlaCar Bus | 16h 50m | 1:35 PM | Prague | ÚAN Florenc | 6:25 AM | Lyon | Perrache Train Station | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/20/2025 1:35:00 PM to Perrache Train Station, Lyon (France) arriving at 7/21/2025 6:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 50m
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BlaBlaCar Bus | 16h 50m | 1:35 PM | Prague | ÚAN Florenc | 6:25 AM | Lyon | Perrache Bus Stop | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/20/2025 1:35:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/21/2025 6:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 50m
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FlixBus | 19h 25m | 3:50 AM | Prague | Wilsonova Bus Station | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $101 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/20/2025 3:50:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/20/2025 11:15:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 19h 25m
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FlixBus | 19h 5m | 4:10 AM | Prague | Na Knížecí Station | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $101 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 7/20/2025 4:10:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/20/2025 11:15:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 19h 5m
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FlixBus | 16h 35m | 6:40 AM | Prague | ÚAN Florenc | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $110 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/20/2025 6:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/20/2025 11:15:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 16h 35m
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Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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FlixBus | 14h 35m | 9:50 PM | Prague | Na Knížecí Station | 12:25 PM | Lyon | Perrache Bus Stop | Economy | $91 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 7/21/2025 9:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/22/2025 12:25:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 14h 35m
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FlixBus | 15h 0m | 9:25 PM | Prague | ÚAN Florenc | 12:25 PM | Lyon | Perrache Bus Stop | Economy | $91 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/21/2025 9:25:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/22/2025 12:25:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 15h 0m
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FlixBus | 17h 20m | 11:15 AM | Prague | Wilsonova Bus Station | 4:35 AM | Lyon | Perrache Bus Stop | Economy | $94 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/21/2025 11:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/22/2025 4:35:00 AM. 50 Economy ticket for $94 per person are available. Travel duration is 17h 20m
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FlixBus | 16h 35m | 6:40 AM | Prague | ÚAN Florenc | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $95 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/21/2025 6:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/21/2025 11:15:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 16h 35m
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FlixBus | 17h 10m | 3:05 PM | Prague | Zličín | 8:15 AM | Lyon | Perrache Bus Stop | Economy | $95 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 7/21/2025 3:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/22/2025 8:15:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 17h 10m
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Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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FlixBus | 14h 35m | 9:50 PM | Prague | Na Knížecí Station | 12:25 PM | Lyon | Perrache Bus Stop | Economy | $83 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 7/22/2025 9:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/23/2025 12:25:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 14h 35m
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FlixBus | 15h 0m | 9:25 PM | Prague | ÚAN Florenc | 12:25 PM | Lyon | Perrache Bus Stop | Economy | $83 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/22/2025 9:25:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/23/2025 12:25:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 0m
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FlixBus | 16h 45m | 4:15 PM | Prague | Wilsonova Bus Station | 9:00 AM | Lyon | Perrache Bus Stop | Economy | $86 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/22/2025 4:15:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/23/2025 9:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 45m
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FlixBus | 17h 0m | 4:00 PM | Prague | ÚAN Florenc | 9:00 AM | Lyon | Perrache Bus Stop | Economy | $86 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/22/2025 4:00:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/23/2025 9:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 0m
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FlixBus | 16h 35m | 6:40 AM | Prague | ÚAN Florenc | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $91 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/22/2025 6:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/22/2025 11:15:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 16h 35m
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Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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FlixBus | 19h 10m | 1:05 PM | Prague | Wilsonova Bus Station | 8:15 AM | Lyon | Perrache Bus Stop | Economy | $83 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/23/2025 1:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/24/2025 8:15:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 10m
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FlixBus | 16h 35m | 6:40 AM | Prague | ÚAN Florenc | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $83 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/23/2025 6:40:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/23/2025 11:15:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 16h 35m
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FlixBus | 19h 25m | 3:50 AM | Prague | Wilsonova Bus Station | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $84 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/23/2025 3:50:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/23/2025 11:15:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 19h 25m
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FlixBus | 19h 5m | 4:10 AM | Prague | Na Knížecí Station | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $84 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 7/23/2025 4:10:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/23/2025 11:15:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 19h 5m
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FlixBus | 16h 45m | 4:15 PM | Prague | Wilsonova Bus Station | 9:00 AM | Lyon | Perrache Bus Stop | Economy | $86 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/23/2025 4:15:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/24/2025 9:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 45m
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Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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BlaBlaCar Bus | 16h 50m | 1:35 PM | Prague | ÚAN Florenc | 6:25 AM | Lyon | Perrache Train Station | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/24/2025 1:35:00 PM to Perrache Train Station, Lyon (France) arriving at 7/25/2025 6:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 50m
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BlaBlaCar Bus | 16h 50m | 1:35 PM | Prague | ÚAN Florenc | 6:25 AM | Lyon | Perrache Bus Stop | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/24/2025 1:35:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/25/2025 6:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 50m
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RegioJet | 15h 50m | 11:00 PM | Prague | ÚAN Florenc | 2:50 PM | Lyon | Perrache Bus Stop | Economy | $81 |
A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 7/24/2025 11:00:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/25/2025 2:50:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 15h 50m
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FlixBus | 16h 45m | 4:15 PM | Prague | Wilsonova Bus Station | 9:00 AM | Lyon | Perrache Bus Stop | Economy | $86 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/24/2025 4:15:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/25/2025 9:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 45m
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FlixBus | 17h 0m | 4:00 PM | Prague | ÚAN Florenc | 9:00 AM | Lyon | Perrache Bus Stop | Economy | $86 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 7/24/2025 4:00:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/25/2025 9:00:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 17h 0m
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Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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BlaBlaCar Bus | 16h 45m | 1:35 PM | Prague | ÚAN Florenc | 6:20 AM | Lyon | Perrache Train Station | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/25/2025 1:35:00 PM to Perrache Train Station, Lyon (France) arriving at 7/26/2025 6:20:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus | 16h 45m | 1:35 PM | Prague | ÚAN Florenc | 6:20 AM | Lyon | Perrache Bus Stop | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/25/2025 1:35:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/26/2025 6:20:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 45m
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FlixBus | 19h 25m | 3:50 AM | Prague | Wilsonova Bus Station | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $95 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/25/2025 3:50:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/25/2025 11:15:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 19h 25m
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FlixBus | 19h 5m | 4:10 AM | Prague | Na Knížecí Station | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $95 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 7/25/2025 4:10:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/25/2025 11:15:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 19h 5m
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BlaBlaCar Bus | 20h 45m | 8:20 AM | Prague | ÚAN Florenc | 5:05 AM | Lyon | Perrache Train Station | Economy | $100 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/25/2025 8:20:00 AM to Perrache Train Station, Lyon (France) arriving at 7/26/2025 5:05:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 20h 45m
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Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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BlaBlaCar Bus | 16h 50m | 1:35 PM | Prague | ÚAN Florenc | 6:25 AM | Lyon | Perrache Train Station | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/26/2025 1:35:00 PM to Perrache Train Station, Lyon (France) arriving at 7/27/2025 6:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 50m
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BlaBlaCar Bus | 16h 50m | 1:35 PM | Prague | ÚAN Florenc | 6:25 AM | Lyon | Perrache Bus Stop | Economy | $70 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/26/2025 1:35:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/27/2025 6:25:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 50m
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BlaBlaCar Bus | 20h 50m | 7:00 PM | Prague | ÚAN Florenc | 3:50 PM | Lyon | Perrache Train Station | Economy | $77 |
A Bus from BlaBlaCar Bus goes from ÚAN Florenc, Prague (Czech Republic) at 7/26/2025 7:00:00 PM to Perrache Train Station, Lyon (France) arriving at 7/27/2025 3:50:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 20h 50m
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FlixBus | 17h 10m | 3:05 PM | Prague | Zličín | 8:15 AM | Lyon | Perrache Bus Stop | Economy | $81 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 7/26/2025 3:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 7/27/2025 8:15:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 17h 10m
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FlixBus | 19h 25m | 3:50 AM | Prague | Wilsonova Bus Station | 11:15 PM | Lyon | Perrache Bus Stop | Economy | $84 |
A Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 7/26/2025 3:50:00 AM to Perrache Bus Stop, Lyon (France) arriving at 7/26/2025 11:15:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 19h 25m
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Frequency of bus connections between Prague and Lyon
Facts about the bus from Prague to Lyon
Compare all providers like FlixBus, BlaBlaCar Bus and RegioJet that travel 15 times every day by bus from Prague to Lyon in one click! Book your bus ticket from Prague to Lyon starting from $70!
Cheapest Bus | $70 |
Fastest Bus | 14h 35m |
Earliest Bus | 3:50 AM |
Latest Bus | 9:50 PM |
Daily Bus Routes | 15 Ø |
Distance | 535.0 miles |
Bus Companies | FlixBus, BlaBlaCar Bus and RegioJet |
Cheapest bus connections from Prague to Lyon
Every day, 15 buses from 3 bus companies leave Prague for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/21/2025 and for the following days.
The cheapest time to travel from Prague to Lyon
How to save money travelling from Prague to Lyon
Book the ticket from Prague to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Lyon are also emptier.All bus stations and stops in Prague and Lyon
In the map below, you can see where to find all bus stations in Prague and Lyon.
Compare the bus with other modes of transport
Service and Comfort on the bus from Prague to Lyon
FAQs about the Prague to Lyon bus
How much does a Prague Lyon bus trip cost?
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On average, how many connections are available from Prague to Lyon each day?
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What time is the last bus from Prague to Lyon?
Which bus companies operate the Prague Lyon route?
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What equipment is available for the Prague Lyon bus route?
Available seat classes which are offered on the bus route Prague to Lyon
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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