Bus Madrid to Lyon: Compare prices and save money

Compare all timetables for the bus from Madrid to Lyon

Here is a selection of the cheapest bus trips from the schedule from Madrid to Lyon from various bus operators like BlaBlaCar Bus or ALSA for the next days.

today

$54

tomorrow

$48

Monday

Tuesday

$48

Wednesday

$39

Thursday

$38

Friday

$38

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	24h 15m	6:35 PM	Madrid	Sur Bus Station	6:50 PM	Lyon	Perrache Train Station	Economy	$54	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/7/2026 6:35:00 PM to Perrache Train Station, Lyon (France) arriving at 2/8/2026 6:50:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 24h 15m
BlaBlaCar Bus	19h 40m	10:30 PM	Madrid	Sur Bus Station	6:10 PM	Lyon	Perrache Train Station	Economy	$60	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/7/2026 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 2/8/2026 6:10:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 19h 40m
BlaBlaCar Bus	23h 10m	3:30 PM	Madrid	Sur Bus Station	2:40 PM	Lyon	Perrache Train Station	Economy	$64	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/7/2026 3:30:00 PM to Perrache Train Station, Lyon (France) arriving at 2/8/2026 2:40:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 23h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ALSA	18h 16m	11:59 PM	Madrid	Avenida de América Bus Station	6:15 PM	Lyon	Perrache Bus Stop	Economy	$48	A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 2/8/2026 11:59:00 PM to Perrache Bus Stop, Lyon (France) arriving at 2/9/2026 6:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 18h 16m
BlaBlaCar Bus	19h 40m	10:30 PM	Madrid	Sur Bus Station	6:10 PM	Lyon	Perrache Train Station	Economy	$60	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/8/2026 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 2/9/2026 6:10:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 19h 40m
BlaBlaCar Bus	24h 15m	6:35 PM	Madrid	Sur Bus Station	6:50 PM	Lyon	Perrache Train Station	Economy	$66	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/8/2026 6:35:00 PM to Perrache Train Station, Lyon (France) arriving at 2/9/2026 6:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 24h 15m
BlaBlaCar Bus	23h 10m	3:30 PM	Madrid	Sur Bus Station	2:40 PM	Lyon	Perrache Train Station	Economy	$74	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/8/2026 3:30:00 PM to Perrache Train Station, Lyon (France) arriving at 2/9/2026 2:40:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 23h 10m
ALSA	19h 15m	11:00 PM	Madrid	Mendez Alvaro Train Station	6:15 PM	Lyon	Perrache Bus Stop	Economy	$129	A Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 2/8/2026 11:00:00 PM to Perrache Bus Stop, Lyon (France) arriving at 2/9/2026 6:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 19h 15m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ALSA	18h 16m	11:59 PM	Madrid	Avenida de América Bus Station	6:15 PM	Lyon	Perrache Bus Stop		Economy	$48	A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 2/10/2026 11:59:00 PM to Perrache Bus Stop, Lyon (France) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 18h 16m
	ALSA	19h 15m	11:00 PM	Madrid	Mendez Alvaro Train Station	6:15 PM	Lyon	Perrache Bus Stop		Economy	$129	A Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 2/10/2026 11:00:00 PM to Perrache Bus Stop, Lyon (France) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 19h 15m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ALSA	16h 45m	8:30 PM	Madrid	Mendez Alvaro Train Station	1:15 PM	Lyon	Perrache Bus Stop	Economy	$39	A Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 2/11/2026 8:30:00 PM to Perrache Bus Stop, Lyon (France) arriving at 2/12/2026 1:15:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 16h 45m
ALSA	17h 25m	8:35 AM	Madrid	Mendez Alvaro Train Station	2:00 AM	Lyon	Perrache Bus Stop	Economy	$39	A Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 2/11/2026 8:35:00 AM to Perrache Bus Stop, Lyon (France) arriving at 2/12/2026 2:00:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 17h 25m
BlaBlaCar Bus	17h 20m	8:35 AM	Madrid	Sur Bus Station	1:55 AM	Lyon	Perrache Train Station	Economy	$64	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/11/2026 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 2/12/2026 1:55:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 17h 20m
BlaBlaCar Bus	19h 40m	10:30 PM	Madrid	Sur Bus Station	6:10 PM	Lyon	Perrache Train Station	Economy	$66	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/11/2026 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 2/12/2026 6:10:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 19h 40m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	ALSA	16h 45m	8:30 PM	Madrid	Mendez Alvaro Train Station	1:15 PM	Lyon	Perrache Bus Stop		Economy	$38	A Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 2/12/2026 8:30:00 PM to Perrache Bus Stop, Lyon (France) arriving at 2/13/2026 1:15:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 16h 45m
	BlaBlaCar Bus	19h 40m	10:30 PM	Madrid	Sur Bus Station	6:10 PM	Lyon	Perrache Train Station		Economy	$68	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/12/2026 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 2/13/2026 6:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 19h 40m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
ALSA	17h 25m	8:35 AM	Madrid	Mendez Alvaro Train Station	2:00 AM	Lyon	Perrache Bus Stop	Economy	$38	A Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 2/13/2026 8:35:00 AM to Perrache Bus Stop, Lyon (France) arriving at 2/14/2026 2:00:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 17h 25m
BlaBlaCar Bus	17h 20m	8:35 AM	Madrid	Sur Bus Station	1:55 AM	Lyon	Perrache Train Station	Economy	$64	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/13/2026 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 2/14/2026 1:55:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 17h 20m
BlaBlaCar Bus	16h 45m	8:30 PM	Madrid	Sur Bus Station	1:15 PM	Lyon	Perrache Train Station	Economy	$64	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 2/13/2026 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 2/14/2026 1:15:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 16h 45m
ALSA	23h 14m	11:00 AM	Madrid	Avenida de América Bus Station	10:14 AM	Lyon	Perrache Bus Stop	Economy	$76	A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 2/13/2026 11:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 2/14/2026 10:14:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 23h 14m
ALSA	21h 14m	1:00 PM	Madrid	Avenida de América Bus Station	10:14 AM	Lyon	Perrache Bus Stop	Economy	$76	A Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 2/13/2026 1:00:00 PM to Perrache Bus Stop, Lyon (France) arriving at 2/14/2026 10:14:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 21h 14m

Best Price Offer: The price for the cheapest bus from Madrid to Lyon is $38 on 2/12/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Madrid and Lyon

See here how frequent the connections between Madrid and Lyon are, during different times and days of the week.

Wednesday is the busiest day, with more than 7 daily buses from Madrid to Lyon. Tuesday has instead the fewest connections, with only 2 daily coaches between Madrid and Lyon.

The busiest time of the day is the Evening, with 17 buses from Madrid to Lyon, while Afternoon sees the fewest connections between Madrid and Lyon, with 4 offers.

Facts about the bus from Madrid to Lyon

Compare all providers like BlaBlaCar Bus and ALSA that travel 4 times every day by bus from Madrid to Lyon in one click! Book your bus ticket from Madrid to Lyon starting from $38!

Cheapest Bus	$38
Fastest Bus	16h 45m
Earliest Bus	3:30 PM
Latest Bus	10:30 PM
Daily Bus Routes	4 Ø
Distance	566.9 miles
Bus Companies	BlaBlaCar Bus and ALSA

Cheapest bus connections from Madrid to Lyon

Every day, 4 buses from 2 bus companies leave Madrid for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/07/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

$72

Sunday 02/08

$47

Monday 02/09

Tuesday 02/10

$47

Wednesday 02/11

$64

Thursday 02/12

$64

Friday 02/13

$64

Saturday 02/14

$64

Sunday 02/15

$64

Monday 02/16

$38

Tuesday 02/17

$62

Wednesday 02/18

$38

Thursday 02/19

$38

Friday 02/20

$38

Saturday 02/21

$64

Sunday 02/22

$64

Monday 02/23

$64

Tuesday 02/24

$47

Wednesday 02/25

$38

Thursday 02/26

$74

Friday 02/27

$38

Saturday 02/28

The cheapest time to travel from Madrid to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Lyon, for the next 30 days.

With a price starting from $38, Thursday is the cheapest day for a bus from Madrid to Lyon. Saturday instead is the most expensive day with prices starting from $54.

Morning is the cheapest day time for bus tickets from Madrid to Lyon, with $38. Afternoon is the most expensive time of the day with prices starting from $64.

How to save money travelling from Madrid to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Lyon are also emptier.

Beloved bus companies from Madrid to Lyon

These are the most booked bus companies between Madrid to Lyon from our users.

BlaBlaCar Bus from Madrid to Lyon

Here you will find the key facts about the BlaBlaCar Bus bus route Madrid to Lyon:

Cheapest Price	$54
Fastest Bus	16h 45m
Earliest Bus	3:30 PM
Last Bus	10:30 PM
Daily Connections	2 Ø
Found on	2/6/2026

Union Ivkoni from Madrid to Lyon

Here you will find the key facts about the Union Ivkoni bus route Madrid to Lyon:

Cheapest Price	$47
Fastest Bus	22h 0m
Earliest Bus	10:00 AM
Last Bus	10:00 AM
Daily Connections	1 Ø
Found on	1/19/2026

Latest reviews for bus companies on the route Madrid - Lyon

Paquito, 11/15/2024

15-11-2024. Había comprado el mes pasado un billete Madrid a Lyon para salir hoy. He hecho ese trayecto varias veces pero era la primera vez a través de BlaBlaCar. La salida de la Estación Sur (Méndez ... 15-11-2024. Había comprado el mes pasado un billete Madrid a Lyon para salir hoy. He hecho ese trayecto varias veces pero era la primera vez a través de BlaBlaCar. La salida de la Estación Sur (Méndez Álvaro) estaba prevista a las 10 horas. Llegué a la estación a las 8 horas. Me paré delante de los paneles de información esas 2 horas. No apareció nunca el anuncio del autobús (su puerta de embarque), ni de ningún autobús con destino a Francia en esas horas. Lo que sí aparecía era el retraso en la llegada de otros autobuses de BBC. Me dirigí a varios puntos de información, alarmado de que nada aparecía. Me rechazaron diciendo que no sabían nada de BlaBlaCar, que "iba a su aire". Además, desde hace muchas semanas la oficina de información de la Estación Sur de Autobuses está cerrada. Cuando se acercó la hora empecé a deambular por la planta baja de la Estación sin dejar de mirar a los paneles de información. A las 10 y media una joven que esperaba en una puerta, y que parecía acostumbrada al funcionamiento del lugar, me preguntó dónde iba. Me informó que mi autobús se había marchado a su hora ("Suelen salir del anden 20", me dijo) pero cuando le pregunté por qué no salía la información en los paneles y que nadie podía informar, se encogió de hombros y me deseó buena suerte. Considero esta operación, responsabilidad de BlaBlaCar, un fraude, un robo y con consecuencias personales importantes: debía presentarme en Lyon el sábado 16 a las 10 de la mañana. Era importante para mi. ¡Desgraciados!

All bus stations and stops in Madrid and Lyon

In the map below, you can see where to find all bus stations in Madrid and Lyon.

Avenida de América Bus Station

Avenida de América 13

Bus Stop

Calle de Tiziano 40

Intercambiador de Moncloa

Calle de la Princesa 89n

Plaza de Castilla

Sur Bus Station

Calle de Méndez Álvaro 83

Perrache Bus Stop

Cours de Verdun 14

Saint Paul Train Station

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Jean-Macé Train Station

Maison Carrée Bus Stop

Les Charrières 69570

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Lyon? Compare all modes of transports from Madrid to Lyon.

Service and Comfort on the bus from Madrid to Lyon

Want to know which seat classes are available on the buses from Madrid to Lyon? Or which bus companies serve the route Madrid to Lyon? Below you will find answers to your questions.

FAQs about the Madrid to Lyon bus

How much does a Madrid Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $38 and takes 16h 45m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Madrid to Lyon?

This route is offered by 2 companies with a range of ticket prices between $38 and $129. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Madrid to Lyon each day?

Every day, the Madrid to Lyon bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Lyon take?

The fastest bus from Madrid to Lyon is offered by BlaBlaCar Bus and takes 16h 45m. Bus tickets for this connection cost $64. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Lyon?

The earliest bus arriving in Lyon from Madrid starts at 3:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Lyon?

The latest bus trip departing from Madrid for Lyon starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Lyon route?

When traveling by bus from Madrid to Lyon, passengers can travel with BlaBlaCar Bus and ALSA. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Lyon?

You can check all the direct connections between Madrid and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: BlaBlaCar Bus and ALSA.

What can I take with me on the Madrid to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Lyon on your planned travel date.

How does CheckMyBus find the best bus deals from Madrid to Lyon?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Madrid and Lyon. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Madrid to Lyon?

Prices and availability for 4 trips between Madrid and Lyon change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Madrid to Lyon

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Lyon

Here’s an overview of the most popular bus routes to Madrid and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!