Bus Mulhouse to Lyon: Compare prices and save money

Compare all timetables for the bus from Mulhouse to Lyon

Here is a selection of the cheapest bus trips from the schedule from Mulhouse to Lyon from various bus operators like FlixBus for the next days.

today

tomorrow

$19

Tuesday

Wednesday

$30

Thursday

$19

Friday

$22

Saturday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	4h 25m	12:10 AM	Mulhouse	Bus Station	4:35 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$19	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/16/2026 12:10:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/16/2026 4:35:00 AM. 50 Economy ticket for $19 per person are available. Travel duration is 4h 25m
FlixBus	5h 45m	6:45 AM	Mulhouse	Bus Station	12:30 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$22	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/16/2026 6:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/16/2026 12:30:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 45m
FlixBus	5h 20m	7:30 AM	Mulhouse	Bus Station	12:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$22	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/16/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/16/2026 12:50:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 20m
FlixBus	5h 10m	3:05 AM	Mulhouse	Bus Station	8:15 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$23	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/16/2026 3:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/16/2026 8:15:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 5h 10m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	12h 10m	8:40 AM	Mulhouse	Bus Station	8:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop		Economy	$30	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/18/2026 8:40:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/18/2026 8:50:00 PM. 50 Economy ticket for $30 per person are available. Travel duration is 12h 10m
	FlixBus	9h 10m	11:05 PM	Mulhouse	Bus Station	8:15 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop		Economy	$30	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/18/2026 11:05:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/19/2026 8:15:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 9h 10m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	5h 45m	6:45 AM	Mulhouse	Bus Station	12:30 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop		Economy	$19	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/19/2026 6:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/19/2026 12:30:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 5h 45m
	FlixBus	5h 10m	3:05 AM	Mulhouse	Bus Station	8:15 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop		Economy	$22	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/19/2026 3:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/19/2026 8:15:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 45m	6:45 AM	Mulhouse	Bus Station	12:30 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$22	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/20/2026 6:45:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/20/2026 12:30:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 45m
FlixBus	5h 20m	7:30 AM	Mulhouse	Bus Station	12:50 PM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$25	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/20/2026 7:30:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/20/2026 12:50:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 5h 20m
FlixBus	5h 10m	3:05 AM	Mulhouse	Bus Station	8:15 AM	Lyon	Lyon Avenue Tony Garnier Bus Stop	Economy	$26	A Bus from FlixBus goes from Bus Station, Mulhouse (France) at 3/20/2026 3:05:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/20/2026 8:15:00 AM. 50 Economy ticket for $26 per person are available. Travel duration is 5h 10m

Best Price Offer: The price for the cheapest bus from Mulhouse to Lyon is $19 on 3/16/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Mulhouse and Lyon

See here how frequent the connections between Mulhouse and Lyon are, during different times and days of the week.

Monday is the busiest day, with more than 4 daily buses from Mulhouse to Lyon. Wednesday has instead the fewest connections, with only 2 daily coaches between Mulhouse and Lyon.

The busiest time of the day is the Morning, with 6 buses from Mulhouse to Lyon, while Evening sees the fewest connections between Mulhouse and Lyon, with 1 offers.

Facts about the bus from Mulhouse to Lyon

Compare all providers like FlixBus that travel 2 times every day by bus from Mulhouse to Lyon in one click! Book your bus ticket from Mulhouse to Lyon starting from $19!

Cheapest Bus	$19
Fastest Bus	4h 25m
Earliest Bus	12:10 AM
Latest Bus	7:30 AM
Daily Bus Routes	2 Ø
Distance	181.6 miles
Bus Companies	FlixBus

Cheapest bus connections from Mulhouse to Lyon

Every day, 2 buses from 1 bus companies leave Mulhouse for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/15/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/15

$21

Monday 03/16

$19

Tuesday 03/17

Wednesday 03/18

$30

Thursday 03/19

$19

Friday 03/20

$22

Saturday 03/21

$20

Sunday 03/22

$22

Monday 03/23

$19

Tuesday 03/24

Wednesday 03/25

$28

Thursday 03/26

$22

Friday 03/27

$21

Saturday 03/28

Sunday 03/29

$22

Monday 03/30

$21

Tuesday 03/31

$23

Wednesday 04/01

$25

Thursday 04/02

$29

Friday 04/03

$46

Saturday 04/04

$31

Sunday 04/05

$31

Monday 04/06

Tuesday 04/07

$29

Wednesday 04/08

$27

Thursday 04/09

$27

Friday 04/10

$21

Saturday 04/11

The cheapest time to travel from Mulhouse to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Mulhouse to Lyon, for the next 30 days.

With a price starting from $19, Monday is the cheapest day for a bus from Mulhouse to Lyon. Wednesday instead is the most expensive day with prices starting from $25.

Morning is the cheapest day time for bus tickets from Mulhouse to Lyon, with $19. Evening is the most expensive time of the day with prices starting from $29.

How to save money travelling from Mulhouse to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mulhouse to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mulhouse to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mulhouse to Lyon are also emptier.

All bus stations and stops in Mulhouse and Lyon

In the map below, you can see where to find all bus stations in Mulhouse and Lyon.

Bus Station

Avenue du Général Leclerc 14

Central Station

Porte-Jeune Bus Stop

Zu-Rhein Bus Stop

Tour Nessel Bus Stop

Perrache Bus Stop

Cours de Verdun 14

Lyon Avenue Tony Garnier Bus Stop

Avenue Tony Garnier 52

Saint Paul Train Station

Pont Kitchener R.G. Bus Stop

Cours de Verdun

Jean-Macé Train Station

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mulhouse to Lyon? Compare all modes of transports from Mulhouse to Lyon.

Service and Comfort on the bus from Mulhouse to Lyon

Want to know which seat classes are available on the buses from Mulhouse to Lyon? Or which bus companies serve the route Mulhouse to Lyon? Below you will find answers to your questions.

FAQs about the Mulhouse to Lyon bus

How much does a Mulhouse Lyon bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $19 and takes 4h 25m to reach Lyon. Compare offers to save money!

How much could I save by comparing buses from Mulhouse to Lyon?

This route is offered by 1 companies with a range of ticket prices between $19 and $30. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Lyon.

On average, how many connections are available from Mulhouse to Lyon each day?

Every day, the Mulhouse to Lyon bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mulhouse to Lyon take?

The fastest bus from Mulhouse to Lyon is offered by FlixBus and takes 4h 25m. Bus tickets for this connection cost $19. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mulhouse to Lyon?

The earliest bus arriving in Lyon from Mulhouse starts at 12:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mulhouse to Lyon?

The latest bus trip departing from Mulhouse for Lyon starts at 7:30 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mulhouse Lyon route?

When traveling by bus from Mulhouse to Lyon, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mulhouse and Lyon?

You can check all the direct connections between Mulhouse and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Mulhouse to Lyon bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mulhouse Lyon bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mulhouse Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mulhouse to Lyon on your planned travel date.

How does CheckMyBus find the best bus deals from Mulhouse to Lyon?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Mulhouse and Lyon. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mulhouse to Lyon?

Prices and availability for 2 trips between Mulhouse and Lyon change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mulhouse to Lyon

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mulhouse and to Lyon

Here’s an overview of the most popular bus routes to Mulhouse and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!