What is the best way to travel from Madrid to Lyon?
Looking for a trip? Compare all the available Flights and Buses for the journey to Lyon from Madrid. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can get to Lyon with just $38 by taking a Bus from ALSA, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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ALSA19h 30m010:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/24/2026 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/25/2026 6:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 19h 30m
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ALSA18h 30m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/24/2026 11:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/25/2026 6:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 18h 30m
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BlaBlaCar Bus24h 15m06:35 PMMadridSur Bus Station6:50 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/24/2026 6:35:00 PM to Perrache Train Station, Lyon (France) arriving at 3/25/2026 6:50:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 24h 15m
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Union Ivkoni22h 0m010:00 AMMadridMendez Alvaro Train Station8:00 AMLyonLyon Avenue Tony Garnier Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/24/2026 10:00:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/25/2026 8:00:00 AM. 50 Basic ticket for $64 per person are available. Travel duration is 22h 0m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/24/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/25/2026 5:40:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 18h 15m
Cheapest Buses Tuesday
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/25/2026 6:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 18h 1m
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ALSA16h 45m09:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:00 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 9:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/26/2026 2:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 16h 45m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/26/2026 5:40:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus17h 20m08:35 AMMadridSur Bus Station1:55 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 3/26/2026 1:55:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 20m
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BlaBlaCar Bus21h 0m011:00 PMMadridSur Bus Station8:00 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 11:00:00 PM to Perrache Train Station, Lyon (France) arriving at 3/26/2026 8:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 21h 0m
Cheapest Buses Wednesday
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ALSA17h 20m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:15 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/27/2026 5:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 17h 20m
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ALSA16h 0m01:15 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:15 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 1:15:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/27/2026 5:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 16h 0m
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BlaBlaCar Bus21h 0m011:00 PMMadridSur Bus Station8:00 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/26/2026 11:00:00 PM to Perrache Train Station, Lyon (France) arriving at 3/27/2026 8:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 21h 0m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/26/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/27/2026 5:40:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 18h 15m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/26/2026 2:50:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/27/2026 10:50:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 20h 0m
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Air Europa14h 25m06:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport9:00 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 6:35:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/26/2026 9:00:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 14h 25m
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Vueling Airlines13h 25m07:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport9:05 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 7:40:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/27/2026 9:05:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 13h 25m
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Volotea1h 45m08:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:40 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 8:55:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/26/2026 10:40:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 1h 45m
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Iberia15h 45m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport3:30 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 11:45:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/27/2026 3:30:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 15h 45m
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Brussels Airlines9h 55m012:35 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:30 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Brussels Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 12:35:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/26/2026 10:30:00 PM. 50 Economy ticket for $208 per person are available. Travel duration is 9h 55m
Cheapest Buses Thursday
Cheapest Flights Thursday
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ALSA17h 25m08:35 AMMadridMendez Alvaro Train Station2:00 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/27/2026 8:35:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/28/2026 2:00:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 17h 25m
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Union Ivkoni23h 0m010:00 AMMadridSur Bus Station9:00 AMLyonLyon Avenue Tony Garnier Bus Stop0BasicA Bus from Union Ivkoni goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:00:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/28/2026 9:00:00 AM. 50 Basic ticket for $46 per person are available. Travel duration is 23h 0m
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/28/2026 1:10:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 18h 40m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/28/2026 5:40:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 18h 15m
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Internorte Transportes17h 25m08:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:00 AMLyonPart-Dieu Train Station0BasicA Bus from Internorte Transportes goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 8:35:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 3/28/2026 2:00:00 AM. 50 Basic ticket for $144 per person are available. Travel duration is 17h 25m
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EasyJet Airline1h 50m05:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T47:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from EasyJet Airline goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 5:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/27/2026 7:30:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m05:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T47:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 5:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/27/2026 7:30:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 1h 50m
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Vueling Airlines10h 5m09:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:35 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 9:30:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/28/2026 7:35:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 10h 5m
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Volotea1h 45m08:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:40 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 8:55:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/27/2026 10:40:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 1h 45m
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Aeronova8h 0m06:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 6:35:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/27/2026 2:35:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 8h 0m
Cheapest Buses Friday
Cheapest Flights Friday
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ALSA15h 45m08:30 PMMadridMendez Alvaro Train Station1:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/28/2026 8:30:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/29/2026 1:15:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 15h 45m
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ALSA15h 10m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:05 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/28/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/29/2026 4:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 15h 10m
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/28/2026 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/29/2026 1:10:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 18h 40m
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FlixBus18h 15m011:25 PMMadridSur Bus Station6:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/28/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/29/2026 6:40:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus20h 0m011:00 PMMadridSur Bus Station8:00 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/28/2026 11:00:00 PM to Perrache Train Station, Lyon (France) arriving at 3/29/2026 8:00:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 20h 0m
Cheapest Buses Saturday
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ALSA18h 30m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 11:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/30/2026 6:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 30m
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ALSA18h 16m011:59 PMMadridAvenida de América Bus Station6:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 3/29/2026 11:59:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/30/2026 6:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 16m
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BlaBlaCar Bus17h 40m07:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 7:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/30/2026 1:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 17h 40m
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Union Ivkoni22h 30m010:00 AMMadridMendez Alvaro Train Station8:30 AMLyonLyon Avenue Tony Garnier Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/29/2026 10:00:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/30/2026 8:30:00 AM. 50 Basic ticket for $72 per person are available. Travel duration is 22h 30m
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BlaBlaCar Bus17h 20m08:35 AMMadridSur Bus Station1:55 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 3/30/2026 1:55:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 20m
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Iberia24h 40m08:25 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Iberia goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 8:25:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/30/2026 9:05:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 40m
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Volotea15h 25m05:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport9:05 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 5:40:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/30/2026 9:05:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 15h 25m
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TAP Portugal13h 30m010:25 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport11:55 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from TAP Portugal goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:25:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/30/2026 11:55:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 13h 30m
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Air Europa25h 30m09:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport11:20 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 9:50:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/30/2026 11:20:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 25h 30m
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Iberia Express4h 35m06:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Iberia Express goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 6:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/29/2026 11:15:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 4h 35m
Cheapest Buses Sunday
Cheapest Flights Sunday
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ALSA16h 10m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:05 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/30/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/31/2026 4:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 16h 10m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/30/2026 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/30/2026 6:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 1m
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/30/2026 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/31/2026 1:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 18h 40m
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BlaBlaCar Bus24h 15m06:35 PMMadridSur Bus Station6:50 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/30/2026 6:35:00 PM to Perrache Train Station, Lyon (France) arriving at 3/31/2026 6:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 24h 15m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/30/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/31/2026 5:40:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 15m
Cheapest Buses Monday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 1h 45m with a Flight from Volotea. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/24/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/25/2026 5:40:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 18h 15m
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ALSA18h 30m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/24/2026 11:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/25/2026 6:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 18h 30m
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ALSA19h 30m010:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/24/2026 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/25/2026 6:15:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 19h 30m
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Union Ivkoni22h 0m010:00 AMMadridMendez Alvaro Train Station8:00 AMLyonLyon Avenue Tony Garnier Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/24/2026 10:00:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/25/2026 8:00:00 AM. 50 Basic ticket for $64 per person are available. Travel duration is 22h 0m
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BlaBlaCar Bus24h 15m06:35 PMMadridSur Bus Station6:50 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/24/2026 6:35:00 PM to Perrache Train Station, Lyon (France) arriving at 3/25/2026 6:50:00 PM. 50 Economy ticket for $63 per person are available. Travel duration is 24h 15m
Fastest Buses Tuesday
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ALSA16h 45m09:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:00 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 9:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/26/2026 2:00:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 16h 45m
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BlaBlaCar Bus17h 20m08:35 AMMadridSur Bus Station1:55 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 3/26/2026 1:55:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 20m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/25/2026 6:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 18h 1m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/26/2026 5:40:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus21h 0m011:00 PMMadridSur Bus Station8:00 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 11:00:00 PM to Perrache Train Station, Lyon (France) arriving at 3/26/2026 8:00:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 21h 0m
Fastest Buses Wednesday
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Volotea1h 45m08:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:40 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 8:55:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/26/2026 10:40:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 1h 45m
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Brussels Airlines9h 55m012:35 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:30 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Brussels Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 12:35:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/26/2026 10:30:00 PM. 50 Economy ticket for $208 per person are available. Travel duration is 9h 55m
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Vueling Airlines13h 25m07:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport9:05 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 7:40:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/27/2026 9:05:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 13h 25m
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Air Europa14h 25m06:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport9:00 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 6:35:00 AM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/26/2026 9:00:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 14h 25m
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Iberia15h 45m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport3:30 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 11:45:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/27/2026 3:30:00 PM. 50 Economy ticket for $166 per person are available. Travel duration is 15h 45m
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ALSA16h 0m01:15 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:15 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 1:15:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/27/2026 5:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 16h 0m
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ALSA17h 20m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:15 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/27/2026 5:15:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 17h 20m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/26/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/27/2026 5:40:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 18h 15m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/26/2026 2:50:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/27/2026 10:50:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 20h 0m
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BlaBlaCar Bus21h 0m011:00 PMMadridSur Bus Station8:00 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/26/2026 11:00:00 PM to Perrache Train Station, Lyon (France) arriving at 3/27/2026 8:00:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 21h 0m
Fastest Flights Thursday
Fastest Buses Thursday
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Volotea1h 45m08:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:40 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 8:55:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/27/2026 10:40:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 1h 45m
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EasyJet Airline1h 50m05:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T47:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from EasyJet Airline goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 5:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/27/2026 7:30:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m05:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T47:30 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 5:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/27/2026 7:30:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 1h 50m
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Aeronova8h 0m06:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 6:35:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/27/2026 2:35:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 8h 0m
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Vueling Airlines10h 5m09:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:35 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 9:30:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/28/2026 7:35:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 10h 5m
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ALSA17h 25m08:35 AMMadridMendez Alvaro Train Station2:00 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/27/2026 8:35:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/28/2026 2:00:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 17h 25m
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Internorte Transportes17h 25m08:35 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:00 AMLyonPart-Dieu Train Station0BasicA Bus from Internorte Transportes goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 8:35:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 3/28/2026 2:00:00 AM. 50 Basic ticket for $144 per person are available. Travel duration is 17h 25m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/28/2026 5:40:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/28/2026 1:10:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 18h 40m
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Union Ivkoni23h 0m010:00 AMMadridSur Bus Station9:00 AMLyonLyon Avenue Tony Garnier Bus Stop0BasicA Bus from Union Ivkoni goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:00:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/28/2026 9:00:00 AM. 50 Basic ticket for $46 per person are available. Travel duration is 23h 0m
Fastest Flights Friday
Fastest Buses Friday
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ALSA15h 10m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:05 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/28/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/29/2026 4:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 15h 10m
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ALSA15h 45m08:30 PMMadridMendez Alvaro Train Station1:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/28/2026 8:30:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/29/2026 1:15:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 15h 45m
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FlixBus18h 15m011:25 PMMadridSur Bus Station6:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/28/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/29/2026 6:40:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/28/2026 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/29/2026 1:10:00 AM. 50 Economy ticket for $81 per person are available. Travel duration is 18h 40m
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BlaBlaCar Bus20h 0m011:00 PMMadridSur Bus Station8:00 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/28/2026 11:00:00 PM to Perrache Train Station, Lyon (France) arriving at 3/29/2026 8:00:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 20h 0m
Fastest Buses Saturday
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Iberia Express4h 35m06:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:15 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Iberia Express goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 6:40:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/29/2026 11:15:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 4h 35m
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TAP Portugal13h 30m010:25 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport11:55 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from TAP Portugal goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:25:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/30/2026 11:55:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 13h 30m
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Volotea15h 25m05:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport9:05 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 5:40:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/30/2026 9:05:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 15h 25m
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Iberia24h 40m08:25 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:05 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Iberia goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 8:25:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 3/30/2026 9:05:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 24h 40m
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Air Europa25h 30m09:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport11:20 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 9:50:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 3/30/2026 11:20:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 25h 30m
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BlaBlaCar Bus17h 20m08:35 AMMadridSur Bus Station1:55 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 3/30/2026 1:55:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 17h 20m
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BlaBlaCar Bus17h 40m07:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 7:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/30/2026 1:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 17h 40m
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ALSA18h 16m011:59 PMMadridAvenida de América Bus Station6:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Avenida de América Bus Station, Madrid (Spain) at 3/29/2026 11:59:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/30/2026 6:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 16m
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ALSA18h 30m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 11:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 3/30/2026 6:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 30m
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Union Ivkoni22h 30m010:00 AMMadridMendez Alvaro Train Station8:30 AMLyonLyon Avenue Tony Garnier Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 3/29/2026 10:00:00 AM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/30/2026 8:30:00 AM. 50 Basic ticket for $72 per person are available. Travel duration is 22h 30m
Fastest Flights Sunday
Fastest Buses Sunday
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ALSA16h 10m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:05 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/30/2026 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/31/2026 4:05:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 16h 10m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/30/2026 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 3/30/2026 6:15:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 18h 1m
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FlixBus18h 15m011:25 PMMadridSur Bus Station5:40 PMLyonLyon Avenue Tony Garnier Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/30/2026 11:25:00 PM to Lyon Avenue Tony Garnier Bus Stop, Lyon (France) arriving at 3/31/2026 5:40:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 18h 15m
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/30/2026 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 3/31/2026 1:10:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 18h 40m
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BlaBlaCar Bus24h 15m06:35 PMMadridSur Bus Station6:50 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/30/2026 6:35:00 PM to Perrache Train Station, Lyon (France) arriving at 3/31/2026 6:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 24h 15m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Atocha Train Station, Sur Bus Station or Chamartin Train Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 7 connections between 7 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as $38 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Volotea: you will get to Lyon in just 1h 45m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, BlaBlaCar Bus and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, BlaBlaCar Bus and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA, BlaBlaCar Bus, FlixBus and 2 more.
Airlines: Volotea, Air Europa, Vueling Airlines and 7 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 7 connections between Flight and Bus, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 566.9 miles.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just $38 by taking a Bus from ALSA.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 45m with a Flight from Volotea.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Castellón de la Plana to Madrid
- Cordoba to Madrid
- Huelva to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Marbella to Madrid
- Mérida to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Seville to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Alicante to Lyon
- Barcelona-El Prat Airport to Lyon
- Brive-la-Gaillarde to Lyon
- Geneva Airport to Lyon
- Lisbon to Lyon
- London to Lyon
- Marseille Airport to Lyon
- Montpellier to Lyon
- Naples to Lyon
- Nice Airport to Lyon
- Nice to Lyon
- Nuremberg to Lyon
- Perpignan to Lyon
- Porto to Lyon
- Prague to Lyon
- Quimper to Lyon
- Rome to Lyon
- Rouen to Lyon
- Strasbourg to Lyon
- Thonon-les-Bains to Lyon
- Turin to Lyon
- Valence to Lyon
- Valencia to Lyon
- Zurich to Lyon
