What is the best way to travel from Madrid to Lyon?
Looking for a trip? Compare all the available Buses, Trains and Flights for the journey to Lyon from Madrid. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 6 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can get to Lyon with just $47 by taking a Bus from ALSA, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 0m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/18/2025 2:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 10:50:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 20h 0m
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FlixBus19h 5m03:45 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/18/2025 3:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 10:50:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 19h 5m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/18/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/19/2025 1:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 45m
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TAP Portugal5h 25m012:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 12:10:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 5:35:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 5h 25m
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Iberia24h 55m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport12:40 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 11:45:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 12/20/2025 12:40:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 24h 55m
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Air Europa16h 45m03:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:55 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 3:10:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 12/19/2025 7:55:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 16h 45m
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Skyscanner23h 55m010:20 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T410:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 10:20:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/19/2025 10:15:00 AM. 50 Economy ticket for $180 per person are available. Travel duration is 23h 55m
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Iryo10h 16m011:22 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/18/2025 11:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/18/2025 9:38:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 10h 16m
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Iryo9h 16m012:22 PMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/18/2025 12:22:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/18/2025 9:38:00 PM. 50 Economy ticket for $186 per person are available. Travel duration is 9h 16m
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Iryo11h 41m09:57 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/18/2025 9:57:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/18/2025 9:38:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 11h 41m
Cheapest Buses Thursday
Cheapest Flights Thursday
Cheapest Trains Thursday
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 12/20/2025 1:10:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 18h 40m
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/20/2025 2:00:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 25m
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ALSA17h 20m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:15 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/19/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 5:15:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 17h 20m
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FlixBus16h 40m09:55 PMMadridSur Bus Station2:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 9:55:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 2:35:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 40m
Cheapest Buses Friday
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ALSA15h 29m07:00 AMMadridMendez Alvaro Train Station10:29 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/20/2025 7:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 10:29:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 29m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/20/2025 2:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 10:50:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 20h 0m
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FlixBus19h 50m03:45 PMMadridSur Bus Station11:35 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/20/2025 3:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 11:35:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 50m
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ALSA18h 10m010:45 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/20/2025 10:45:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 4:55:00 AM. 50 Basic ticket for $76 per person are available. Travel duration is 18h 10m
Cheapest Buses Saturday
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BlaBlaCar Bus17h 40m06:30 AMMadridSur Bus Station12:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 12/22/2025 12:10:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 17h 40m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/21/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/22/2025 2:00:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 17h 25m
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Union Ivkoni22h 30m010:00 AMMadridMendez Alvaro Train Station8:30 AMLyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/21/2025 10:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 8:30:00 AM. 50 Basic ticket for $87 per person are available. Travel duration is 22h 30m
Cheapest Buses Sunday
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/22/2025 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 12/23/2025 1:10:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 18h 40m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/22/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 6:15:00 PM. 50 Basic ticket for $70 per person are available. Travel duration is 18h 1m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/22/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 4:55:00 AM. 50 Basic ticket for $76 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/22/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/23/2025 1:15:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 16h 45m
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Iryo15h 29m06:09 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 6:09:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $214 per person are available. Travel duration is 15h 29m
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Iryo12h 48m08:50 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 8:50:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 12h 48m
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Iryo10h 16m011:22 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 11:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 10h 16m
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Iryo9h 16m012:22 PMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 12:22:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 9h 16m
Cheapest Buses Monday
Cheapest Trains Monday
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ALSA17h 10m011:45 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/23/2025 11:45:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 10m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/23/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/24/2025 1:15:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 16h 45m
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Union Ivkoni22h 0m010:00 AMMadridMendez Alvaro Train Station8:00 AMLyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/23/2025 10:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 8:00:00 AM. 50 Basic ticket for $78 per person are available. Travel duration is 22h 0m
Cheapest Buses Tuesday
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FlixBus21h 0m07:05 PMMadridSur Bus Station4:05 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 4:05:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 21h 0m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/24/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 6:15:00 PM. 50 Basic ticket for $70 per person are available. Travel duration is 18h 1m
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FlixBus20h 20m08:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:10 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/24/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 5:10:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 20h 20m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/25/2025 1:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 16h 45m
Cheapest Buses Wednesday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 5h 25m with a Flight from TAP Portugal. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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TAP Portugal5h 25m012:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:35 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 12:10:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/18/2025 5:35:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 5h 25m
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Volotea10h 25m012:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:55 PMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Volotea goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 12:30:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 12/18/2025 10:55:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 10h 25m
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Air Europa16h 45m03:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:55 AMLyons St. Exupery AirportLyons St. Exupery Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 3:10:00 PM to Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) arriving at 12/19/2025 7:55:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 16h 45m
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Skyscanner23h 55m010:20 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T410:15 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 10:20:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/19/2025 10:15:00 AM. 50 Economy ticket for $180 per person are available. Travel duration is 23h 55m
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Iryo9h 16m012:22 PMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/18/2025 12:22:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/18/2025 9:38:00 PM. 50 Economy ticket for $186 per person are available. Travel duration is 9h 16m
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Iryo10h 16m011:22 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/18/2025 11:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/18/2025 9:38:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 10h 16m
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Iryo11h 41m09:57 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/18/2025 9:57:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/18/2025 9:38:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 11h 41m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/18/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/19/2025 1:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 16h 45m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/18/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 0m
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FlixBus19h 5m03:45 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/18/2025 3:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 10:50:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 19h 5m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/18/2025 2:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/19/2025 10:50:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 20h 0m
Fastest Flights Thursday
Fastest Trains Thursday
Fastest Buses Thursday
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FlixBus16h 40m09:55 PMMadridSur Bus Station2:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 9:55:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 2:35:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 40m
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ALSA17h 20m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:15 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/19/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 5:15:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 17h 20m
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/20/2025 2:00:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 17h 25m
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BlaBlaCar Bus18h 40m06:30 AMMadridSur Bus Station1:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 12/20/2025 1:10:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 18h 40m
Fastest Buses Friday
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ALSA15h 29m07:00 AMMadridMendez Alvaro Train Station10:29 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/20/2025 7:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/20/2025 10:29:00 PM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 29m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/20/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/21/2025 1:15:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 16h 45m
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ALSA18h 10m010:45 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/20/2025 10:45:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 4:55:00 AM. 50 Basic ticket for $76 per person are available. Travel duration is 18h 10m
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FlixBus19h 50m03:45 PMMadridSur Bus Station11:35 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/20/2025 3:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/21/2025 11:35:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 50m
Fastest Buses Saturday
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/21/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/22/2025 2:00:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 17h 25m
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BlaBlaCar Bus17h 40m06:30 AMMadridSur Bus Station12:10 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 6:30:00 AM to Perrache Train Station, Lyon (France) arriving at 12/22/2025 12:10:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 17h 40m
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Union Ivkoni22h 30m010:00 AMMadridMendez Alvaro Train Station8:30 AMLyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/21/2025 10:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 8:30:00 AM. 50 Basic ticket for $87 per person are available. Travel duration is 22h 30m
Fastest Buses Sunday
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Iryo9h 16m012:22 PMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 12:22:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 9h 16m
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Iryo10h 16m011:22 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 11:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $223 per person are available. Travel duration is 10h 16m
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Iryo11h 41m09:57 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 9:57:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $231 per person are available. Travel duration is 11h 41m
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Iryo12h 48m08:50 AMMadridAtocha Train Station9:38 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/22/2025 8:50:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/22/2025 9:38:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 12h 48m
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FlixBus16h 40m09:55 PMMadridSur Bus Station2:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/22/2025 9:55:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 2:35:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 16h 40m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/22/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/23/2025 1:15:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 16h 45m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/22/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/23/2025 4:55:00 AM. 50 Basic ticket for $76 per person are available. Travel duration is 17h 0m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/22/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/22/2025 6:15:00 PM. 50 Basic ticket for $70 per person are available. Travel duration is 18h 1m
Fastest Trains Monday
Fastest Buses Monday
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FlixBus16h 40m09:55 PMMadridSur Bus Station2:35 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 9:55:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 2:35:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 40m
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/24/2025 1:15:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 16h 45m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/23/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 0m
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ALSA17h 10m011:45 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/23/2025 11:45:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 4:55:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 17h 10m
Fastest Buses Tuesday
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BlaBlaCar Bus16h 45m08:30 PMMadridSur Bus Station1:15 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 8:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/25/2025 1:15:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 16h 45m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0BasicA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/24/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/24/2025 6:15:00 PM. 50 Basic ticket for $70 per person are available. Travel duration is 18h 1m
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FlixBus20h 20m08:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:10 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/24/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 5:10:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 20h 20m
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FlixBus21h 0m07:05 PMMadridSur Bus Station4:05 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 7:05:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/25/2025 4:05:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 21h 0m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Atocha Train Station, Chamartin Train Station or Sur Bus Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 6 connections between 6 Bus, Train and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as $47 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from TAP Portugal: you will get to Lyon in just 5h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, BlaBlaCar Bus and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, BlaBlaCar Bus and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA, BlaBlaCar Bus, FlixBus and 1 more.
Train companies: Iryo
Airlines: TAP Portugal, Iberia, Air Europa and 2 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 6 connections between Bus, Train and Flight, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 566.9 miles.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just $47 by taking a Bus from ALSA.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 5h 25m with a Flight from TAP Portugal.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- A Coruña to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Castellón de la Plana to Madrid
- Gandía to Madrid
- Huelva to Madrid
- León to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Molina de Aragón to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Algeciras to Lyon
- Barcelona to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Chamonix to Lyon
- Clermont-Ferrand to Lyon
- Geneva Airport to Lyon
- Girona to Lyon
- Kehl to Lyon
- Liege to Lyon
- Marseille to Lyon
- Milan to Lyon
- Montpellier to Lyon
- Mulhouse to Lyon
- Nantes to Lyon
- Naples to Lyon
- Narbonne to Lyon
- Paris to Lyon
- Poitiers to Lyon
- Prague to Lyon
- Strasbourg to Lyon
- Toulon to Lyon
- Tours to Lyon
- Zurich to Lyon

