What is the best way to travel from Madrid to Lyon?
Looking for a trip? Compare all the available Buses, Trains and Flights for the journey to Lyon from Madrid. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Madrid?
You can get to Lyon with just $54 by taking a Bus from ALSA, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/5/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/6/2025 2:00:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 25m
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BlaBlaCar Bus19h 40m010:30 PMMadridSur Bus Station6:10 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/5/2025 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/6/2025 6:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 19h 40m
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Union Ivkoni23h 0m010:00 AMMadridMendez Alvaro Train Station9:00 AMLyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/5/2025 10:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/6/2025 9:00:00 AM. 50 Basic ticket for $68 per person are available. Travel duration is 23h 0m
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ALSA20h 59m01:15 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T410:14 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/5/2025 1:15:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/6/2025 10:14:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 20h 59m
Cheapest Buses Friday
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ALSA18h 10m010:45 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 10:45:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/7/2025 4:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 10m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/7/2025 4:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus19h 40m010:30 PMMadridSur Bus Station6:10 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/6/2025 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/7/2025 6:10:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 40m
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FlixBus16h 40m08:50 PMMadridSur Bus Station1:30 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/6/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/7/2025 1:30:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 40m
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Air Nostrum1h 50m09:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:45 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 9:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/6/2025 11:45:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 1h 50m
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TAP Portugal5h 55m06:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 6:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/6/2025 11:55:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 5h 55m
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Skyscanner13h 35m010:20 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 10:20:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/6/2025 11:55:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 13h 35m
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Air France18h 25m04:25 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T410:50 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air France goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 4:25:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/7/2025 10:50:00 AM. 50 Economy ticket for $216 per person are available. Travel duration is 18h 25m
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Iryo10h 14m011:22 AMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 11:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 10h 14m
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Iryo9h 14m012:22 PMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 12:22:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 9h 14m
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Iryo13h 29m08:07 AMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 8:07:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 13h 29m
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Iryo12h 14m09:22 AMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 9:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 12h 14m
Cheapest Buses Saturday
Cheapest Flights Saturday
Cheapest Trains Saturday
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/7/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 4:55:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 0m
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ALSA19h 30m010:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/7/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 6:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 19h 30m
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Union Ivkoni22h 30m010:00 AMMadridMendez Alvaro Train Station8:30 AMLyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/7/2025 10:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 8:30:00 AM. 50 Basic ticket for $77 per person are available. Travel duration is 22h 30m
Cheapest Buses Sunday
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/8/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 6:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 18h 1m
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ALSA18h 40m010:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/8/2025 10:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/9/2025 4:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 18h 40m
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FlixBus16h 40m08:50 PMMadridSur Bus Station1:30 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/8/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/9/2025 1:30:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 40m
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FlixBus20h 20m08:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:10 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/8/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/9/2025 5:10:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 20h 20m
Cheapest Buses Monday
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ALSA19h 30m010:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/9/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 6:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 19h 30m
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ALSA18h 30m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/9/2025 11:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 6:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 18h 30m
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Union Ivkoni22h 0m010:00 AMMadridMendez Alvaro Train Station8:00 AMLyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/9/2025 10:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 8:00:00 AM. 50 Basic ticket for $68 per person are available. Travel duration is 22h 0m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 2:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 10:50:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 20h 0m
Cheapest Buses Tuesday
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/10/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 6:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 18h 1m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/10/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/11/2025 4:55:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/10/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/11/2025 2:00:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 17h 25m
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FlixBus16h 40m08:50 PMMadridSur Bus Station1:30 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/10/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/11/2025 1:30:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 40m
Cheapest Buses Wednesday
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/11/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 4:55:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus24h 10m06:35 PMMadridSur Bus Station6:45 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 6:35:00 PM to Perrache Train Station, Lyon (France) arriving at 12/12/2025 6:45:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 24h 10m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 2:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 10:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 20h 0m
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FlixBus19h 5m03:45 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 3:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 10:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 19h 5m
Cheapest Buses Thursday
What are the fastest trips from Madrid to Lyon?
You can get to Lyon from Madrid in just 1h 50m with a Flight from Air Nostrum. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/5/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/6/2025 2:00:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 17h 25m
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ALSA18h 10m010:45 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/5/2025 10:45:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/6/2025 4:55:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 10m
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BlaBlaCar Bus19h 40m010:30 PMMadridSur Bus Station6:10 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/5/2025 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/6/2025 6:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 19h 40m
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ALSA20h 59m01:15 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T410:14 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/5/2025 1:15:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/6/2025 10:14:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 20h 59m
Fastest Buses Friday
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Air Nostrum1h 50m09:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:45 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 9:55:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/6/2025 11:45:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 1h 50m
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Brussels Airlines4h 45m06:25 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:10 AMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Brussels Airlines goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 6:25:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/6/2025 11:10:00 AM. 50 Economy ticket for $225 per person are available. Travel duration is 4h 45m
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TAP Portugal5h 55m06:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 6:00:00 PM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/6/2025 11:55:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 5h 55m
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Skyscanner13h 35m010:20 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:55 PMLyons St. Exupery AirportAéroport St Exupéry Bus Station0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 10:20:00 AM to Aéroport St Exupéry Bus Station, Lyons St. Exupery Airport (France) arriving at 12/6/2025 11:55:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 13h 35m
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Iryo9h 14m012:22 PMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 12:22:00 PM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 9h 14m
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Iryo10h 14m011:22 AMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 11:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 10h 14m
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Iryo11h 39m09:57 AMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 9:57:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 11h 39m
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Iryo12h 14m09:22 AMMadridAtocha Train Station9:36 PMLyonPart-Dieu Train Station0EconomyA Train from Iryo goes from Atocha Train Station, Madrid (Spain) at 12/6/2025 9:22:00 AM to Part-Dieu Train Station, Lyon (France) arriving at 12/6/2025 9:36:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 12h 14m
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FlixBus16h 40m08:50 PMMadridSur Bus Station1:30 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/6/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/7/2025 1:30:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 16h 40m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/7/2025 4:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 17h 0m
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ALSA18h 10m010:45 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/6/2025 10:45:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/7/2025 4:55:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 18h 10m
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BlaBlaCar Bus19h 40m010:30 PMMadridSur Bus Station6:10 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/6/2025 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/7/2025 6:10:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 19h 40m
Fastest Flights Saturday
Fastest Trains Saturday
Fastest Buses Saturday
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/7/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 4:55:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 0m
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ALSA19h 30m010:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/7/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 6:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 19h 30m
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Union Ivkoni22h 30m010:00 AMMadridMendez Alvaro Train Station8:30 AMLyonPerrache Bus Stop0BasicA Bus from Union Ivkoni goes from Mendez Alvaro Train Station, Madrid (Spain) at 12/7/2025 10:00:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 8:30:00 AM. 50 Basic ticket for $77 per person are available. Travel duration is 22h 30m
Fastest Buses Sunday
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FlixBus16h 40m08:50 PMMadridSur Bus Station1:30 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/8/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/9/2025 1:30:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 16h 40m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/8/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/8/2025 6:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 18h 1m
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ALSA18h 40m010:15 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/8/2025 10:15:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/9/2025 4:55:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 18h 40m
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FlixBus20h 20m08:50 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T45:10 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/8/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/9/2025 5:10:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 20h 20m
Fastest Buses Monday
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ALSA18h 30m011:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/9/2025 11:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 6:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 18h 30m
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FlixBus19h 5m03:45 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 3:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 10:50:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 19h 5m
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ALSA19h 30m010:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/9/2025 10:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 6:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 19h 30m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 2:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 10:50:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 20h 0m
Fastest Buses Tuesday
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FlixBus16h 40m08:50 PMMadridSur Bus Station1:30 PMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/10/2025 8:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/11/2025 1:30:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 16h 40m
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/10/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/11/2025 4:55:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 17h 0m
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BlaBlaCar Bus17h 25m08:35 AMMadridSur Bus Station2:00 AMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/10/2025 8:35:00 AM to Perrache Train Station, Lyon (France) arriving at 12/11/2025 2:00:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 17h 25m
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ALSA18h 1m012:14 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T46:15 PMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/10/2025 12:14:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/10/2025 6:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 18h 1m
Fastest Buses Wednesday
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ALSA17h 0m011:55 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T44:55 AMLyonPerrache Bus Stop0EconomyA Bus from ALSA goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 12/11/2025 11:55:00 AM to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 4:55:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 17h 0m
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FlixBus19h 5m03:45 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 3:45:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 10:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 19h 5m
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BlaBlaCar Bus19h 40m010:30 PMMadridSur Bus Station6:10 PMLyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 10:30:00 PM to Perrache Train Station, Lyon (France) arriving at 12/12/2025 6:10:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 19h 40m
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FlixBus20h 0m02:50 PMMadridSur Bus Station10:50 AMLyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 2:50:00 PM to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 10:50:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 20h 0m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Madrid to Lyon
What are the most popular stations in Madrid and Lyon?
In Madrid, you will usually depart from Atocha Train Station, Chamartin Train Station or Sur Bus Station, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Madrid? With 6 connections between 5 Bus, Train and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Lyon, you can pay as low as $54 with a Bus from ALSA.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Nostrum: you will get to Lyon in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Lyon are ALSA, BlaBlaCar Bus and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Caluire-et-Cuire, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Lyon?
The most popular companies between Madrid and Lyon, are ALSA, BlaBlaCar Bus and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA, BlaBlaCar Bus, FlixBus and 1 more.
Train companies: Iryo
Airlines: Air Nostrum, TAP Portugal, Skyscanner and 2 more.
All you need to know when you travel from Madrid to Lyon
Check all information on comfort and services on all modes of transports from Madrid to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Lyon
How can I reach Lyon from Madrid?
Every day, there are on average 6 connections between Bus, Train and Flight, with which you can get to Lyon from Madrid.
How far is Lyon from Madrid?
The distance between Madrid and Lyon is 566.9 miles.
What is the most ecofriendly mode of transport between Madrid and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 155 kgs, and a flight 224 kgs.
What is the cheapest mode of transport from Madrid to Lyon?
You can get to Lyon with just $54 by taking a Bus from ALSA.
What is the fastest way to get from Madrid to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 1h 50m with a Flight from Air Nostrum.
More routes to Madrid and to Lyon
Looking for more options? Here you can see the most popular routes to Madrid and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- A Coruña to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Cáceres (ES) to Madrid
- Castellón de la Plana to Madrid
- Gandía to Madrid
- Huelva to Madrid
- León to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santander to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Bordeaux to Lyon
- Frankfurt am Main to Lyon
- Geneva to Lyon
- Lisbon to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Moulins to Lyon
- Mulhouse to Lyon
- Nuremberg to Lyon
- Paris to Lyon
- Rome to Lyon
- Rouen to Lyon
- Saint-Étienne to Lyon
- Toulouse to Lyon
- Tours to Lyon
- Turin to Lyon
- Valence to Lyon
- Valencia to Lyon
- Venice to Lyon
- Viseu to Lyon

