Bus from Milan to Prague from $51

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Compare all timetables for the bus from Milan to Prague

Here is a selection of the cheapest bus trips from the schedule from Milan to Prague from various bus operators like FlixBus or RegioJet for the next days.
today
from $68
tomorrow
from $60
Wednesday
from $55
Thursday
from $51
Friday
from $64
Saturday
from $64
Sunday
from $59

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    13h 50m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    11:00 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $68
  • FlixBus
    13h 40m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    10:50 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $68
  • FlixBus
    17h 0m
    0
    11:10 PM
    Milan
    Lampugnano Bus Station
    4:10 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $77
  • FlixBus
    14h 10m
    0
    9:20 PM
    Milan
    Lampugnano Bus Station
    11:30 AM
    Prague
    Zličín
    0
    FlixBus
    Economy
    $78
  • FlixBus
    18h 25m
    0
    11:10 PM
    Milan
    Lampugnano Bus Station
    5:35 PM
    Prague
    Hradčanská
    0
    FlixBus
    Economy
    $78
  • Did you know that if you travel from Milan to Prague via Munich, you can save more than $12? You can find the corresponding connections below.
    • FlixBus
      16h 55m
      0
      9:20 PM
      Milan
      Lampugnano Bus Station
      4:55 AM
      Munich
      Central Bus Station
      0
      FlixBus
      Economy
      $36
      • Waiting Time 4h 35m
    • RegioJet
      4h 45m
      0
      9:30 AM
      Munich
      Central Bus Station
      2:15 PM
      Prague
      ÚAN Florenc
      0
      RegioJet
      Economy
      $20
    Travel time is 3h 15m longer, but you will save $12

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    13h 40m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    10:50 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $60
  • FlixBus
    13h 50m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    11:00 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $60
  • FlixBus
    15h 30m
    0
    11:45 AM
    Milan
    Lampugnano Bus Station
    3:15 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $64
  • FlixBus
    17h 10m
    0
    5:25 PM
    Milan
    Lampugnano Bus Station
    10:35 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $64
  • FlixBus
    16h 25m
    0
    4:30 PM
    Milan
    Lampugnano Bus Station
    8:55 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $64

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    13h 40m
    0
    7:50 AM
    Milan
    Lampugnano Bus Station
    9:30 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $55
  • FlixBus
    17h 0m
    0
    11:10 PM
    Milan
    Lampugnano Bus Station
    4:10 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $71
  • FlixBus
    16h 25m
    0
    4:30 PM
    Milan
    Lampugnano Bus Station
    8:55 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $71
  • FlixBus
    18h 55m
    0
    4:50 PM
    Milan
    Lampugnano Bus Station
    11:45 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $71
  • FlixBus
    16h 50m
    0
    4:30 PM
    Milan
    Lampugnano Bus Station
    9:20 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $71

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    13h 40m
    0
    7:50 AM
    Milan
    Lampugnano Bus Station
    9:30 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $51
  • FlixBus
    17h 0m
    0
    11:10 PM
    Milan
    Lampugnano Bus Station
    4:10 PM
    Prague
    Černý Most
    0
    FlixBus
    Economy
    $69
  • FlixBus
    15h 10m
    0
    7:25 PM
    Milan
    Lampugnano Bus Station
    10:35 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $70
  • FlixBus
    14h 50m
    0
    9:20 PM
    Milan
    Lampugnano Bus Station
    12:10 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $70
  • FlixBus
    17h 45m
    0
    11:45 PM
    Milan
    Lampugnano Bus Station
    5:30 PM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $70

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    13h 40m
    0
    7:50 AM
    Milan
    Lampugnano Bus Station
    9:30 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $64
  • FlixBus
    13h 40m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    10:50 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $66
  • FlixBus
    13h 50m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    11:00 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $66
  • FlixBus
    15h 30m
    0
    11:45 AM
    Milan
    Lampugnano Bus Station
    3:15 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $80
  • FlixBus
    16h 25m
    0
    4:30 PM
    Milan
    Lampugnano Bus Station
    8:55 AM
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    $80
  • Did you know that if you travel from Milan to Prague via Munich, you can save more than $12? You can find the corresponding connections below.
    • BlaBlaCar Bus
      18h 5m
      0
      12:20 PM
      Milan
      Lampugnano Bus Station
      9:00 PM
      Munich
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $32
      • Waiting Time 3h 40m
    • RegioJet
      5h 45m
      0
      12:40 AM
      Munich
      Central Bus Station
      6:25 AM
      Prague
      Train station Wilsonova
      0
      RegioJet
      Economy
      $20
    Travel time is 4h 25m longer, but you will save $12

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    13h 40m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    10:50 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $64
  • FlixBus
    13h 50m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    11:00 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $64
  • FlixBus
    13h 40m
    0
    7:50 AM
    Milan
    Lampugnano Bus Station
    9:30 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $66
  • FlixBus
    13h 15m
    0
    2:00 PM
    Milan
    Lampugnano Bus Station
    3:15 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $74
  • FlixBus
    15h 25m
    0
    6:00 PM
    Milan
    Lampugnano Bus Station
    9:25 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $74
  • Did you know that if you travel from Milan to Prague via Munich, you can save more than $18? You can find the corresponding connections below.
    • BlaBlaCar Bus
      14h 25m
      0
      11:50 PM
      Milan
      Lampugnano Bus Station
      7:25 AM
      Munich
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $32
      • Waiting Time 2h 5m
    • RegioJet
      4h 45m
      0
      9:30 AM
      Munich
      Central Bus Station
      2:15 PM
      Prague
      ÚAN Florenc
      0
      RegioJet
      Economy
      $13
    Travel time is 1h 10m longer, but you will save $18

Cheapest bus trips Sunday

Prices are for one way and one person
  • RegioJet
    14h 45m
    0
    3:40 PM
    Milan
    Lampugnano Bus Station
    6:25 AM
    Prague
    Train station Wilsonova
    0
    RegioJet
    Economy
    $59
  • RegioJet
    14h 48m
    0
    3:40 PM
    Milan
    Lampugnano Bus Station
    6:28 AM
    Prague
    ÚAN Florenc
    0
    RegioJet
    Economy
    $59
  • FlixBus
    13h 40m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    10:50 AM
    Prague
    Wilsonova Bus Station
    0
    FlixBus
    Economy
    $66
  • FlixBus
    13h 50m
    0
    9:10 PM
    Milan
    Lampugnano Bus Station
    11:00 AM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $66
  • FlixBus
    13h 40m
    0
    7:50 AM
    Milan
    Lampugnano Bus Station
    9:30 PM
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    $68
  • Did you know that if you travel from Milan to Prague via Munich, you can save more than $13? You can find the corresponding connections below.
    • BlaBlaCar Bus
      14h 25m
      0
      11:50 PM
      Milan
      Lampugnano Bus Station
      7:25 AM
      Munich
      Central Bus Station
      0
      BlaBlaCar Bus
      Economy
      $32
      • Waiting Time 2h 5m
    • RegioJet
      4h 45m
      0
      9:30 AM
      Munich
      Central Bus Station
      2:15 PM
      Prague
      ÚAN Florenc
      0
      RegioJet
      Economy
      $13
    Travel time is 0h 45m longer, but you will save $13

Frequency of bus connections between Milan and Prague

See here how frequent the connections between Milan and Prague are, during different times and days of the week.
Friday is the busiest day, with more than 33 daily buses from Milan to Prague. Tuesday has instead the fewest connections, with only 19 daily coaches between Milan and Prague.
The busiest time of the day is the Evening, with 84 buses from Milan to Prague, while Night sees the fewest connections between Milan and Prague, with 30 offers.

Facts about the bus from Milan to Prague

Compare all providers like FlixBus and RegioJet that travel 27 times every day by bus from Milan to Prague in one click! Book your bus ticket from Milan to Prague starting from $51!

Cheapest Bus $51
Fastest Bus 13h 15m
Earliest Bus 4:10 AM
Latest Bus 11:10 PM
Daily Bus Routes 27 Ø
Distance 401.1 miles
Bus Companies FlixBus and RegioJet

Cheapest bus connections from Milan to Prague

Every day, 27 buses from 2 bus companies leave Milan for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/18
Monday 05/19
$68
Tuesday 05/20
$60
Wednesday 05/21
$55
Thursday 05/22
$51
Friday 05/23
$64
Saturday 05/24
$64
Sunday 05/25
$66
Monday 05/26
$50
Tuesday 05/27
$54
Wednesday 05/28
$49
Thursday 05/29
$54
Friday 05/30
$68
Saturday 05/31
$68
Sunday 06/01
$68
Monday 06/02
$62
Tuesday 06/03
$62
Wednesday 06/04
$51
Thursday 06/05
$51
Friday 06/06
$64
Saturday 06/07
$58
Sunday 06/08
$60
Monday 06/09
$63
Tuesday 06/10
$57
Wednesday 06/11
$54
Thursday 06/12
$51
Friday 06/13
$55
Saturday 06/14

The cheapest time to travel from Milan to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Milan to Prague, for the next 30 days.
With a price starting from $51, Thursday is the cheapest day for a bus from Milan to Prague. Monday instead is the most expensive day with prices starting from $68.
Morning is the cheapest day time for bus tickets from Milan to Prague, with $51. Night is the most expensive time of the day with prices starting from $65.

How to save money travelling from Milan to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Milan to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Milan to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Milan to Prague are also emptier.

All bus stations and stops in Milan and Prague

In the map below, you can see where to find all bus stations in Milan and Prague.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Milan to Prague? Compare all modes of transports from Milan to Prague.

Service and Comfort on the bus from Milan to Prague

Want to know which seat classes are available on the buses from Milan to Prague? Or which bus companies serve the route Milan to Prague? Below you will find answers to your questions.

FAQs about the Milan to Prague bus

How much does a Milan Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $51 and takes 13h 40m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Milan to Prague?

This route is offered by 2 companies with a range of ticket prices between $51 and $108. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Milan to Prague each day?

Every day, the Milan to Prague bus route is served by approximately 27 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Milan to Prague take?

The fastest bus from Milan to Prague is offered by FlixBus and takes 13h 15m. Bus tickets for this connection cost $86. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Milan to Prague?

The earliest bus arriving in Prague from Milan starts at 4:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Milan to Prague?

The latest bus trip departing from Milan for Prague starts at 11:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Milan Prague route?

When traveling by bus from Milan to Prague, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Milan and Prague?

You can check all the direct connections between Milan and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Milan to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Milan Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Milan Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Milan to Prague on your planned travel date.

Available seat classes which are offered on the bus route Milan to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Milan and to Prague

Here’s an overview of the most popular bus routes to Milan and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus from Chamonix to Milan Bus from Chamonix to Milan
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Buses to Prague from Liberec Buses to Prague from Liberec
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Buses to Prague from Belgrade Buses to Prague from Belgrade
Bus Budapest - Prague Bus Budapest - Prague
Popular Airport Shuttles to Milan and to Prague
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