Bus Mannheim to Prague - Compare all Companies

Compare all timetables for the bus from Mannheim to Prague

Here is a selection of the cheapest bus trips from the schedule from Mannheim to Prague from various bus operators like FlixBus for the next days.

today

tomorrow

$74

Saturday

$38

Sunday

Monday

$35

Tuesday

Wednesday

$34

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	3:35 PM	Mannheim	Central Bus Station	10:55 PM	Prague	Na Knížecí Station	Economy	$74	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/5/2025 3:35:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/5/2025 10:55:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 7h 20m
FlixBus	7h 35m	3:35 PM	Mannheim	Central Bus Station	11:10 PM	Prague	ÚAN Florenc	Economy	$74	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/5/2025 3:35:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/5/2025 11:10:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 7h 35m
FlixBus	8h 50m	3:35 PM	Mannheim	Central Bus Station	12:25 AM	Prague	Wilsonova Bus Station	Economy	$93	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/5/2025 3:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/6/2025 12:25:00 AM. 50 Economy ticket for $93 per person are available. Travel duration is 8h 50m
FlixBus	6h 40m	3:25 AM	Mannheim	Central Bus Station	10:05 AM	Prague	Na Knížecí Station	Economy	$104	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/5/2025 3:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/5/2025 10:05:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 6h 40m
FlixBus	7h 10m	3:25 AM	Mannheim	Central Bus Station	10:35 AM	Prague	ÚAN Florenc	Economy	$104	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/5/2025 3:25:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/5/2025 10:35:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 7h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 5m	3:50 PM	Mannheim	Central Bus Station	10:55 PM	Prague	Na Knížecí Station	Economy	$38	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/6/2025 3:50:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/6/2025 10:55:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 5m
FlixBus	7h 20m	3:50 PM	Mannheim	Central Bus Station	11:10 PM	Prague	ÚAN Florenc	Economy	$38	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/6/2025 3:50:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/6/2025 11:10:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 20m
FlixBus	7h 25m	5:00 AM	Mannheim	Central Bus Station	12:25 PM	Prague	Na Knížecí Station	Economy	$45	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/6/2025 5:00:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/6/2025 12:25:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 7h 25m
FlixBus	7h 45m	5:00 AM	Mannheim	Central Bus Station	12:45 PM	Prague	ÚAN Florenc	Economy	$45	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/6/2025 5:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/6/2025 12:45:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 7h 45m
FlixBus	8h 35m	3:50 PM	Mannheim	Central Bus Station	12:25 AM	Prague	Wilsonova Bus Station	Economy	$49	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/6/2025 3:50:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/7/2025 12:25:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 8h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 20m	3:35 PM	Mannheim	Central Bus Station	10:55 PM	Prague	Na Knížecí Station	Economy	$35	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/8/2025 3:35:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/8/2025 10:55:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 7h 20m
FlixBus	7h 35m	3:35 PM	Mannheim	Central Bus Station	11:10 PM	Prague	ÚAN Florenc	Economy	$35	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/8/2025 3:35:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/8/2025 11:10:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 7h 35m
FlixBus	7h 25m	5:00 AM	Mannheim	Central Bus Station	12:25 PM	Prague	Na Knížecí Station	Economy	$38	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/8/2025 5:00:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/8/2025 12:25:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 25m
FlixBus	7h 45m	5:00 AM	Mannheim	Central Bus Station	12:45 PM	Prague	ÚAN Florenc	Economy	$38	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/8/2025 5:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/8/2025 12:45:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 7h 45m
FlixBus	8h 50m	3:35 PM	Mannheim	Central Bus Station	12:25 AM	Prague	Wilsonova Bus Station	Economy	$42	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/8/2025 3:35:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/9/2025 12:25:00 AM. 50 Economy ticket for $42 per person are available. Travel duration is 8h 50m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 10m	3:25 AM	Mannheim	Central Bus Station	10:35 AM	Prague	ÚAN Florenc	Economy	$34	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/10/2025 3:25:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/10/2025 10:35:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 10m
FlixBus	7h 35m	3:35 PM	Mannheim	Central Bus Station	11:10 PM	Prague	ÚAN Florenc	Economy	$34	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/10/2025 3:35:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/10/2025 11:10:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 35m
FlixBus	6h 40m	3:25 AM	Mannheim	Central Bus Station	10:05 AM	Prague	Na Knížecí Station	Economy	$34	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/10/2025 3:25:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/10/2025 10:05:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 6h 40m
FlixBus	7h 20m	3:35 PM	Mannheim	Central Bus Station	10:55 PM	Prague	Na Knížecí Station	Economy	$34	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/10/2025 3:35:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/10/2025 10:55:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 7h 20m
FlixBus	7h 45m	5:00 AM	Mannheim	Central Bus Station	12:45 PM	Prague	ÚAN Florenc	Economy	$37	A Bus from FlixBus goes from Central Bus Station, Mannheim (Germany) at 12/10/2025 5:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/10/2025 12:45:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 7h 45m

Best Price Offer: The price for the cheapest bus from Mannheim to Prague is $33 on 12/2/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Mannheim and Prague

See here how frequent the connections between Mannheim and Prague are, during different times and days of the week.

Monday is the busiest day, with more than 7 daily buses from Mannheim to Prague. Friday has instead the fewest connections, with only 5 daily coaches between Mannheim and Prague.

The busiest time of the day is the Night, with 14 buses from Mannheim to Prague, while Afternoon sees the fewest connections between Mannheim and Prague, with 11 offers.

Facts about the bus from Mannheim to Prague

Compare all providers like FlixBus that travel 6 times every day by bus from Mannheim to Prague in one click! Book your bus ticket from Mannheim to Prague starting from $33!

Cheapest Bus	$33
Fastest Bus	6h 40m
Earliest Bus	3:25 AM
Latest Bus	3:35 PM
Daily Bus Routes	6 Ø
Distance	269.5 miles
Bus Companies	FlixBus

Cheapest bus connections from Mannheim to Prague

Every day, 6 buses from 1 bus companies leave Mannheim for Prague: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$74

Saturday 12/06

$38

Sunday 12/07

Monday 12/08

$35

Tuesday 12/09

Wednesday 12/10

$34

Thursday 12/11

$37

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

$41

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Mannheim to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Mannheim to Prague, for the next 30 days.

With a price starting from $34, Wednesday is the cheapest day for a bus from Mannheim to Prague. Friday instead is the most expensive day with prices starting from $74.

Afternoon is the cheapest day time for bus tickets from Mannheim to Prague, with $34. Afternoon is the most expensive time of the day with prices starting from $34.

How to save money travelling from Mannheim to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mannheim to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mannheim to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mannheim to Prague are also emptier.

All bus stations and stops in Mannheim and Prague

In the map below, you can see where to find all bus stations in Mannheim and Prague.

Central Bus Station

Heinrich-von-Stephan-Str 6-8

Theresienkrankenhaus

Boveristraße Bus Stop

Na Knížecí Station

Za Ženskými domovy / Ostrovského

ÚAN Florenc

Křižíkova 279

Wilsonova Bus Station

Wilsonova 300/8

Zličín

K Metru 4

Želivského

J. Želivského

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mannheim to Prague? Compare all modes of transports from Mannheim to Prague.

Service and Comfort on the bus from Mannheim to Prague

Want to know which seat classes are available on the buses from Mannheim to Prague? Or which bus companies serve the route Mannheim to Prague? Below you will find answers to your questions.

FAQs about the Mannheim to Prague bus

How much does a Mannheim Prague bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $33 and takes 7h 10m to reach Prague. Compare offers to save money!

How much could I save by comparing buses from Mannheim to Prague?

This route is offered by 1 companies with a range of ticket prices between $33 and $104. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Prague.

On average, how many connections are available from Mannheim to Prague each day?

Every day, the Mannheim to Prague bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mannheim to Prague take?

The fastest bus from Mannheim to Prague is offered by FlixBus and takes 6h 40m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mannheim to Prague?

The earliest bus arriving in Prague from Mannheim starts at 3:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mannheim to Prague?

The latest bus trip departing from Mannheim for Prague starts at 3:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mannheim Prague route?

When traveling by bus from Mannheim to Prague, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mannheim and Prague?

You can check all the direct connections between Mannheim and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Mannheim to Prague bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mannheim Prague bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mannheim Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mannheim to Prague on your planned travel date.

Available seat classes which are offered on the bus route Mannheim to Prague

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mannheim and to Prague

Here’s an overview of the most popular bus routes to Mannheim and to Prague. Simply click on the connection of your choice, and you will find all the details about your bus route!