Bus from Prague to Milan from $40

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Compare all timetables for the bus from Prague to Milan

Here is a selection of the cheapest bus trips from the schedule from Prague to Milan from various bus operators like FlixBus or RegioJet for the next days.

today
$61
tomorrow
$54
Tuesday
$48
Wednesday
$61
Thursday
$58
Friday
$53
Saturday
$54

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 45m 10:20 AM Prague ÚAN Florenc 12:05 AM Milan Lampugnano Bus Station  Economy $61
FlixBus 15h 25m 9:25 PM Prague ÚAN Florenc 12:50 PM Milan Lampugnano Bus Station  Economy $74
FlixBus 18h 5m 11:45 PM Prague ÚAN Florenc 5:50 PM Milan Lampugnano Bus Station  Economy $74
FlixBus 12h 35m 2:15 PM Prague Wilsonova Bus Station 2:50 AM Milan Lampugnano Bus Station  Economy $76
FlixBus 12h 50m 2:00 PM Prague ÚAN Florenc 2:50 AM Milan Lampugnano Bus Station  Economy $76
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $16? You can find the corresponding connections below.
    • RegioJet
      14h 35m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      7h 45m
      0
      4:20 PM
      Munich
      Central Bus Station
      12:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel time is 2h 0m longer, but you will save $16

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 45m 10:20 AM Prague ÚAN Florenc 12:05 AM Milan Lampugnano Bus Station  Economy $54
FlixBus 14h 55m 11:50 PM Prague Wilsonova Bus Station 2:45 PM Milan Lampugnano Bus Station  Economy $63
FlixBus 18h 35m 10:15 PM Prague Na Knížecí Station 4:50 PM Milan Lampugnano Bus Station  Economy $64
FlixBus 15h 10m 11:35 PM Prague ÚAN Florenc 2:45 PM Milan Lampugnano Bus Station  Economy $64
FlixBus 15h 5m 9:00 AM Prague Wilsonova Bus Station 12:05 AM Milan Lampugnano Bus Station  Economy $68
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $9? You can find the corresponding connections below.
    • RegioJet
      14h 35m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      7h 45m
      0
      4:20 PM
      Munich
      Central Bus Station
      12:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel time is 0h 50m longer, but you will save $9

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 45m 10:20 AM Prague ÚAN Florenc 12:05 AM Milan Lampugnano Bus Station  Economy $48
FlixBus 15h 10m 8:55 AM Prague Zličín 12:05 AM Milan Lampugnano Bus Station  Economy $62
FlixBus 13h 45m 7:25 PM Prague Zličín 9:10 AM Milan Lampugnano Bus Station  Economy $62
FlixBus 15h 40m 5:30 PM Prague Wilsonova Bus Station 9:10 AM Milan Lampugnano Bus Station  Economy $62
FlixBus 14h 25m 9:40 AM Prague Na Knížecí Station 12:05 AM Milan Lampugnano Bus Station  Economy $62

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 0m 6:05 PM Prague Wilsonova Bus Station 12:05 PM Milan Lampugnano Bus Station  Economy $61
FlixBus 16h 55m 9:20 AM Prague ÚAN Florenc 2:15 AM Milan Lampugnano Bus Station  Economy $62
FlixBus 18h 5m 11:45 PM Prague ÚAN Florenc 5:50 PM Milan Lampugnano Bus Station  Economy $62
FlixBus 16h 35m 9:40 AM Prague Na Knížecí Station 2:15 AM Milan Lampugnano Bus Station  Economy $62
FlixBus 19h 50m 9:00 AM Prague Wilsonova Bus Station 4:50 AM Milan Lampugnano Bus Station  Economy $67
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $16? You can find the corresponding connections below.
    • RegioJet
      14h 35m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      7h 45m
      0
      4:20 PM
      Munich
      Central Bus Station
      12:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel Time is 2h 0m shorter, and you will save $16

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 40m 2:30 PM Prague Černý Most 9:10 AM Milan Lampugnano Bus Station  Economy $58
FlixBus 16h 55m 9:20 AM Prague ÚAN Florenc 2:15 AM Milan Lampugnano Bus Station  Economy $62
FlixBus 18h 5m 11:45 PM Prague ÚAN Florenc 5:50 PM Milan Lampugnano Bus Station  Economy $62
FlixBus 16h 35m 9:40 AM Prague Na Knížecí Station 2:15 AM Milan Lampugnano Bus Station  Economy $62
FlixBus 17h 5m 5:15 PM Prague ÚAN Florenc 10:20 AM Milan San Donato Bus Station  Economy $62
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $13? You can find the corresponding connections below.
    • RegioJet
      14h 35m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      7h 45m
      0
      4:20 PM
      Munich
      Central Bus Station
      12:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel Time is 2h 0m shorter, and you will save $13

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 45m 10:20 AM Prague ÚAN Florenc 12:05 AM Milan Lampugnano Bus Station  Economy $53
FlixBus 18h 5m 11:45 PM Prague ÚAN Florenc 5:50 PM Milan Lampugnano Bus Station  Economy $63
FlixBus 15h 5m 9:00 AM Prague Wilsonova Bus Station 12:05 AM Milan Lampugnano Bus Station  Economy $64
RegioJet 14h 0m 11:00 PM Prague ÚAN Florenc 1:00 PM Milan Lampugnano Bus Station  Economy $77
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $8? You can find the corresponding connections below.
    • RegioJet
      14h 35m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      7h 45m
      0
      4:20 PM
      Munich
      Central Bus Station
      12:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel time is 0h 50m longer, but you will save $8

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 45m 10:20 AM Prague ÚAN Florenc 12:05 AM Milan Lampugnano Bus Station  Economy $54
FlixBus 15h 45m 7:30 PM Prague ÚAN Florenc 11:15 AM Milan Lampugnano Bus Station  Economy $63
FlixBus 17h 20m 11:50 PM Prague Wilsonova Bus Station 5:10 PM Milan San Donato Bus Station  Economy $64
FlixBus 17h 35m 11:35 PM Prague ÚAN Florenc 5:10 PM Milan San Donato Bus Station  Economy $64
FlixBus 15h 5m 9:00 AM Prague Wilsonova Bus Station 12:05 AM Milan Lampugnano Bus Station  Economy $65
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $9? You can find the corresponding connections below.
    • RegioJet
      14h 35m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $14
      • Waiting Time 2h 5m
    • FlixBus
      7h 45m
      0
      4:20 PM
      Munich
      Central Bus Station
      12:05 AM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $31
    Travel time is 0h 50m longer, but you will save $9

Best Price Offer: The price for the cheapest bus from Prague to Milan is $40 on 2/24/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Prague and Milan

See here how frequent the connections between Prague and Milan are, during different times and days of the week.
Friday is the busiest day, with more than 37 daily buses from Prague to Milan. Wednesday has instead the fewest connections, with only 17 daily coaches between Prague and Milan.
The busiest time of the day is the Afternoon, with 78 buses from Prague to Milan, while Night sees the fewest connections between Prague and Milan, with 8 offers.

Facts about the bus from Prague to Milan

Compare all providers like FlixBus and RegioJet that travel 27 times every day by bus from Prague to Milan in one click! Book your bus ticket from Prague to Milan starting from $40!

Cheapest Bus $40
Fastest Bus 12h 35m
Earliest Bus 8:55 AM
Latest Bus 11:50 PM
Daily Bus Routes 27 Ø
Distance 401.1 miles
Bus Companies FlixBus and RegioJet

Cheapest bus connections from Prague to Milan

Every day, 27 buses from 2 bus companies leave Prague for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/08/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/08
$61
Monday 02/09
$54
Tuesday 02/10
$48
Wednesday 02/11
$61
Thursday 02/12
$62
Friday 02/13
$53
Saturday 02/14
$54
Sunday 02/15
$56
Monday 02/16
$48
Tuesday 02/17
$47
Wednesday 02/18
$56
Thursday 02/19
$56
Friday 02/20
$47
Saturday 02/21
$45
Sunday 02/22
$48
Monday 02/23
$42
Tuesday 02/24
$40
Wednesday 02/25
$55
Thursday 02/26
$56
Friday 02/27
$48
Saturday 02/28
$48
Sunday 03/01
$46
Monday 03/02
$42
Tuesday 03/03
$41
Wednesday 03/04
$54
Thursday 03/05
$53
Friday 03/06
$45
Saturday 03/07

The cheapest time to travel from Prague to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Milan, for the next 30 days.
With a price starting from $40, Tuesday is the cheapest day for a bus from Prague to Milan. Wednesday instead is the most expensive day with prices starting from $54.
Night is the cheapest day time for bus tickets from Prague to Milan, with $40. Evening is the most expensive time of the day with prices starting from $61.

How to save money travelling from Prague to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Milan are also emptier.

All bus stations and stops in Prague and Milan

In the map below, you can see where to find all bus stations in Prague and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Milan? Compare all modes of transports from Prague to Milan.

Service and Comfort on the bus from Prague to Milan

Want to know which seat classes are available on the buses from Prague to Milan? Or which bus companies serve the route Prague to Milan? Below you will find answers to your questions.

FAQs about the Prague to Milan bus

How much does a Prague Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $40 and takes 13h 45m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Prague to Milan?

This route is offered by 2 companies with a range of ticket prices between $40 and $200. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Prague to Milan each day?

Every day, the Prague to Milan bus route is served by approximately 27 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Milan take?

The fastest bus from Prague to Milan is offered by FlixBus and takes 12h 35m. Bus tickets for this connection cost $76. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Milan?

The earliest bus arriving in Milan from Prague starts at 8:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Milan?

The latest bus trip departing from Prague for Milan starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Milan route?

When traveling by bus from Prague to Milan, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Milan?

You can check all the direct connections between Prague and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Prague to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 27 daily trips between Prague and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Milan?

Prices and availability for 27 trips between Prague and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Milan

Here’s an overview of the most popular bus routes to Prague and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Bremen - Prague Buses Bremen - Prague
Stuttgart to Prague bus Stuttgart to Prague bus
Bus from Kysak to Prague Bus from Kysak to Prague
Bus Zlín to Prague Bus Zlín to Prague
Bus Pescara - Milan Bus Pescara - Milan
Bus Prato - Milan Bus Prato - Milan
Buses Bari to Milan Buses Bari to Milan
Bus from Brescia to Milan Bus from Brescia to Milan
Popular Airport Shuttles to Prague and to Milan
CheckMyBus › Buses in Czech Republic › Bus to Prague › Bus to Milan

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