Bus from Prague to Milan from $48

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Compare all timetables for the bus from Prague to Milan

Here is a selection of the cheapest bus trips from the schedule from Prague to Milan from various bus operators like FlixBus or RegioJet for the next days.
today
from $68
tomorrow
from $66
Sunday
from $72
Monday
from $53
Tuesday
from $48
Wednesday
from $65
Thursday
from $50

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    14h 5m
    0
    7:05 PM
    Prague
    Wilsonova Bus Station
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $68
  • FlixBus
    14h 15m
    0
    6:55 PM
    Prague
    ÚAN Florenc
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $68
  • FlixBus
    13h 35m
    0
    10:20 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $72
  • RegioJet
    14h 0m
    0
    11:00 PM
    Prague
    ÚAN Florenc
    1:00 PM
    Milan
    Lampugnano Bus Station
    0
    RegioJet
    Economy
    $73
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $13? You can find the corresponding connections below.
    • RegioJet
      14h 30m
      0
      4:30 PM
      Prague
      ÚAN Florenc
      9:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $22
      • Waiting Time 2h 15m
    • BlaBlaCar Bus
      7h 30m
      0
      11:30 PM
      Munich
      Central Bus Station
      7:00 AM
      Milan
      Lampugnano Bus Station
      0
      BlaBlaCar Bus
      Economy
      $32
    Travel time is 0h 55m longer, but you will save $13

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    13h 35m
    0
    10:20 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $66
  • FlixBus
    14h 5m
    0
    7:05 PM
    Prague
    Wilsonova Bus Station
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $68
  • FlixBus
    14h 15m
    0
    6:55 PM
    Prague
    ÚAN Florenc
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $68
  • FlixBus
    18h 20m
    0
    1:05 PM
    Prague
    Wilsonova Bus Station
    7:25 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $79
  • FlixBus
    17h 5m
    0
    5:15 PM
    Prague
    Wilsonova Bus Station
    10:20 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $79
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $11? You can find the corresponding connections below.
    • RegioJet
      14h 25m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $20
      • Waiting Time 1h 55m
    • FlixBus
      7h 45m
      0
      4:10 PM
      Munich
      Central Bus Station
      11:55 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $35
    Travel time is 0h 50m longer, but you will save $11

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    14h 5m
    0
    7:05 PM
    Prague
    Wilsonova Bus Station
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $72
  • FlixBus
    14h 15m
    0
    6:55 PM
    Prague
    ÚAN Florenc
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $72
  • FlixBus
    13h 35m
    0
    10:20 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $79
  • FlixBus
    14h 55m
    0
    11:50 PM
    Prague
    Wilsonova Bus Station
    2:45 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $83
  • FlixBus
    16h 25m
    0
    8:15 PM
    Prague
    Wilsonova Bus Station
    12:40 PM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $83
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $21? You can find the corresponding connections below.
    • RegioJet
      14h 25m
      0
      9:30 AM
      Prague
      ÚAN Florenc
      2:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $18
      • Waiting Time 1h 55m
    • FlixBus
      7h 45m
      0
      4:10 PM
      Munich
      Central Bus Station
      11:55 PM
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      $33
    Travel time is 0h 50m longer, but you will save $21

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    13h 35m
    0
    10:20 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    14h 5m
    0
    7:05 PM
    Prague
    Wilsonova Bus Station
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $54
  • FlixBus
    14h 15m
    0
    6:55 PM
    Prague
    ÚAN Florenc
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $54
  • FlixBus
    17h 20m
    0
    5:00 PM
    Prague
    ÚAN Florenc
    10:20 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    17h 35m
    0
    11:35 PM
    Prague
    ÚAN Florenc
    5:10 PM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $65

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    13h 35m
    0
    10:20 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $48
  • FlixBus
    13h 35m
    0
    5:15 PM
    Prague
    Wilsonova Bus Station
    6:50 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    17h 5m
    0
    5:15 PM
    Prague
    Wilsonova Bus Station
    10:20 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    18h 10m
    0
    5:45 PM
    Prague
    Na Knížecí Station
    11:55 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    13h 45m
    0
    7:25 PM
    Prague
    Zličín
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $65

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    18h 20m
    0
    2:30 AM
    Prague
    Wilsonova Bus Station
    8:50 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    18h 50m
    0
    7:25 AM
    Prague
    Wilsonova Bus Station
    2:15 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    18h 0m
    0
    6:05 PM
    Prague
    Wilsonova Bus Station
    12:05 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    17h 20m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    9:10 PM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    17h 5m
    0
    5:15 PM
    Prague
    Wilsonova Bus Station
    10:20 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $65
  • Did you know that if you travel from Prague to Milan via Munich, you can save more than $15? You can find the corresponding connections below.
    • RegioJet
      14h 30m
      0
      4:30 PM
      Prague
      ÚAN Florenc
      9:15 PM
      Munich
      Central Bus Station
      0
      RegioJet
      Economy
      $18
      • Waiting Time 2h 15m
    • BlaBlaCar Bus
      7h 30m
      0
      11:30 PM
      Munich
      Central Bus Station
      7:00 AM
      Milan
      Lampugnano Bus Station
      0
      BlaBlaCar Bus
      Economy
      $32
    Travel Time is 2h 35m shorter, and you will save $15

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    13h 35m
    0
    10:20 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $50
  • FlixBus
    14h 5m
    0
    7:05 PM
    Prague
    Wilsonova Bus Station
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    14h 15m
    0
    6:55 PM
    Prague
    ÚAN Florenc
    9:10 AM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    14h 55m
    0
    11:50 PM
    Prague
    Wilsonova Bus Station
    2:45 PM
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    $60
  • FlixBus
    17h 5m
    0
    5:15 PM
    Prague
    Na Knížecí Station
    10:20 AM
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    $60

Frequency of bus connections between Prague and Milan

See here how frequent the connections between Prague and Milan are, during different times and days of the week.
Sunday is the busiest day, with more than 35 daily buses from Prague to Milan. Wednesday has instead the fewest connections, with only 23 daily coaches between Prague and Milan.
The busiest time of the day is the Afternoon, with 90 buses from Prague to Milan, while Night sees the fewest connections between Prague and Milan, with 21 offers.

Facts about the bus from Prague to Milan

Compare all providers like FlixBus and RegioJet that travel 31 times every day by bus from Prague to Milan in one click! Book your bus ticket from Prague to Milan starting from $48!

Cheapest Bus $48
Fastest Bus 12h 45m
Earliest Bus 2:30 AM
Latest Bus 11:50 PM
Daily Bus Routes 31 Ø
Distance 401.1 miles
Bus Companies FlixBus and RegioJet

Cheapest bus connections from Prague to Milan

Every day, 31 buses from 2 bus companies leave Prague for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/16/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
Wednesday 05/14
Thursday 05/15
Friday 05/16
$68
Saturday 05/17
$66
Sunday 05/18
$72
Monday 05/19
$53
Tuesday 05/20
$48
Wednesday 05/21
$65
Thursday 05/22
$50
Friday 05/23
$57
Saturday 05/24
$53
Sunday 05/25
$60
Monday 05/26
$23
Tuesday 05/27
$23
Wednesday 05/28
$66
Thursday 05/29
$23
Friday 05/30
$23
Saturday 05/31
$23
Sunday 06/01
$73
Monday 06/02
$23
Tuesday 06/03
$23
Wednesday 06/04
$23
Thursday 06/05
$23
Friday 06/06
$71
Saturday 06/07

The cheapest time to travel from Prague to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Milan, for the next 30 days.
With a price starting from $48, Tuesday is the cheapest day for a bus from Prague to Milan. Sunday instead is the most expensive day with prices starting from $72.
Morning is the cheapest day time for bus tickets from Prague to Milan, with $48. Night is the most expensive time of the day with prices starting from $61.

How to save money travelling from Prague to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Prague to Milan are also emptier.

All bus stations and stops in Prague and Milan

In the map below, you can see where to find all bus stations in Prague and Milan.

Service and Comfort on the bus from Prague to Milan

Want to know which seat classes are available on the buses from Prague to Milan? Or which bus companies serve the route Prague to Milan? Below you will find answers to your questions.

FAQs about the Prague to Milan bus

How much does a Prague Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $48 and takes 13h 35m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Prague to Milan?

This route is offered by 2 companies with a range of ticket prices between $48 and $150. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Prague to Milan each day?

Every day, the Prague to Milan bus route is served by approximately 31 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Prague to Milan take?

The fastest bus from Prague to Milan is offered by FlixBus and takes 12h 45m. Bus tickets for this connection cost $84. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Prague to Milan?

The earliest bus arriving in Milan from Prague starts at 2:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Prague to Milan?

The latest bus trip departing from Prague for Milan starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Prague Milan route?

When traveling by bus from Prague to Milan, passengers can travel with FlixBus and RegioJet. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Prague and Milan?

You can check all the direct connections between Prague and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and RegioJet.

What can I take with me on the Prague to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Prague Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Milan on your planned travel date.

Available seat classes which are offered on the bus route Prague to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Milan

Here’s an overview of the most popular bus routes to Prague and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Liberec - Prague Buses Liberec - Prague
Buses Istanbul to Prague Buses Istanbul to Prague
Buses Belgrade - Prague Buses Belgrade - Prague
Budapest to Prague bus Budapest to Prague bus
Bus Lucerne to Milan Bus Lucerne to Milan
Buses to Milan from Bern Buses to Milan from Bern
Bus from Chamonix to Milan Bus from Chamonix to Milan
Buses Bolzano to Milan Buses Bolzano to Milan
Popular Airport Shuttles to Prague and to Milan
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