Bus from Madrid to Brussels from $52

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Compare all timetables for the bus from Madrid to Brussels

Here is a selection of the cheapest bus trips from the schedule from Madrid to Brussels from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today
from $55
tomorrow
from $64
Friday
from $58
Saturday
Sunday
from $60
Monday
from $58
Tuesday
from $52

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    24h 5m
    0
    3:45 PM
    Madrid
    Sur Bus Station
    3:50 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    24h 30m
    0
    3:45 PM
    Madrid
    Sur Bus Station
    4:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    26h 10m
    0
    3:45 PM
    Madrid
    Sur Bus Station
    5:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $65
  • BlaBlaCar Bus
    23h 50m
    0
    6:20 PM
    Madrid
    Sur Bus Station
    6:10 PM
    Brussels
    North Station
    0
    BlaBlaCar Bus
    Economy
    $65
  • BlaBlaCar Bus
    20h 55m
    0
    6:20 PM
    Madrid
    Sur Bus Station
    3:15 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $74

Cheapest bus trips tomorrow

Prices are for one way and one person
  • BlaBlaCar Bus
    21h 15m
    0
    10:30 PM
    Madrid
    Sur Bus Station
    7:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $64
  • FlixBus
    22h 0m
    0
    12:40 AM
    Madrid
    Sur Bus Station
    10:40 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $65
  • FlixBus
    24h 30m
    0
    3:45 PM
    Madrid
    Sur Bus Station
    4:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $67
  • FlixBus
    24h 5m
    0
    3:45 PM
    Madrid
    Sur Bus Station
    3:50 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $67
  • BlaBlaCar Bus
    20h 55m
    0
    6:20 PM
    Madrid
    Sur Bus Station
    3:15 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $70

Cheapest bus trips Friday

Prices are for one way and one person
  • FlixBus
    22h 0m
    0
    12:40 AM
    Madrid
    Sur Bus Station
    10:40 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $58
  • BlaBlaCar Bus
    21h 15m
    0
    10:30 PM
    Madrid
    Sur Bus Station
    7:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $72
  • BlaBlaCar Bus
    20h 55m
    0
    6:20 PM
    Madrid
    Sur Bus Station
    3:15 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $92
  • FlixBus
    24h 30m
    0
    3:45 PM
    Madrid
    Sur Bus Station
    4:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $107
  • FlixBus
    24h 5m
    0
    3:45 PM
    Madrid
    Sur Bus Station
    3:50 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $107

Cheapest bus trips Sunday

Prices are for one way and one person
  • BlaBlaCar Bus
    21h 15m
    0
    10:30 PM
    Madrid
    Sur Bus Station
    7:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $60
  • FlixBus
    22h 0m
    0
    12:40 AM
    Madrid
    Sur Bus Station
    10:40 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $68
  • BlaBlaCar Bus
    20h 55m
    0
    6:20 PM
    Madrid
    Sur Bus Station
    3:15 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $93
  • FlixBus
    21h 50m
    0
    8:25 PM
    Madrid
    Sur Bus Station
    6:15 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $123
  • FlixBus
    21h 30m
    0
    8:25 PM
    Madrid
    Sur Bus Station
    5:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $123
  • Did you know that if you travel from Madrid to Brussels via Paris Orly Airport, you can save more than $13? You can find the corresponding connections below.
    • Busbud
      26h 25m
      0
      3:30 PM
      Madrid
      Sur Bus Station
      9:55 AM
      Paris Orly Airport
      Paris Orly Airport - Parking P4C
      0
      Busbud
      Economy
      $29
      • Waiting Time 2h 20m
    • FlixBus
      5h 40m
      0
      12:15 PM
      Paris Orly Airport
      Paris Orly Airport - Parking P4C
      5:55 PM
      Brussels
      Midi Bus Station
      0
      FlixBus
      Economy
      $18
    Travel time is 5h 30m longer, but you will save $13

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    22h 0m
    0
    12:40 AM
    Madrid
    Sur Bus Station
    10:40 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $58
  • BlaBlaCar Bus
    21h 15m
    0
    10:30 PM
    Madrid
    Sur Bus Station
    7:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $64
  • BlaBlaCar Bus
    22h 10m
    0
    6:20 PM
    Madrid
    Sur Bus Station
    4:30 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $70
  • FlixBus
    22h 30m
    0
    4:40 PM
    Madrid
    Sur Bus Station
    3:10 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $95
  • FlixBus
    23h 10m
    0
    4:40 PM
    Madrid
    Sur Bus Station
    3:50 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $95
  • Did you know that if you travel from Madrid to Brussels via Paris Orly Airport, you can save more than $11? You can find the corresponding connections below.
    • Busbud
      26h 25m
      0
      3:30 PM
      Madrid
      Sur Bus Station
      9:55 AM
      Paris Orly Airport
      Paris Orly Airport - Parking P4C
      0
      Busbud
      Economy
      $29
      • Waiting Time 2h 20m
    • FlixBus
      5h 40m
      0
      12:15 PM
      Paris Orly Airport
      Paris Orly Airport - Parking P4C
      5:55 PM
      Brussels
      Midi Bus Station
      0
      FlixBus
      Economy
      $18
    Travel time is 5h 10m longer, but you will save $11

Cheapest bus trips Tuesday

Prices are for one way and one person
  • BlaBlaCar Bus
    21h 15m
    0
    10:30 PM
    Madrid
    Sur Bus Station
    7:45 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $52
  • FlixBus
    22h 0m
    0
    12:40 AM
    Madrid
    Sur Bus Station
    10:40 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • BlaBlaCar Bus
    22h 10m
    0
    6:20 PM
    Madrid
    Sur Bus Station
    4:30 PM
    Brussels
    Midi Bus Station
    0
    BlaBlaCar Bus
    Economy
    $75
  • FlixBus
    24h 5m
    0
    8:25 PM
    Madrid
    Sur Bus Station
    8:30 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $88
  • FlixBus
    21h 30m
    0
    8:25 PM
    Madrid
    Sur Bus Station
    5:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $88
  • Did you know that if you travel from Madrid to Brussels via Paris Orly Airport, you can save more than $5? You can find the corresponding connections below.
    • Busbud
      26h 25m
      0
      3:30 PM
      Madrid
      Sur Bus Station
      9:55 AM
      Paris Orly Airport
      Paris Orly Airport - Parking P4C
      0
      Busbud
      Economy
      $29
      • Waiting Time 2h 20m
    • FlixBus
      5h 40m
      0
      12:15 PM
      Paris Orly Airport
      Paris Orly Airport - Parking P4C
      5:55 PM
      Brussels
      Midi Bus Station
      0
      FlixBus
      Economy
      $18
    Travel time is 5h 10m longer, but you will save $5

Frequency of bus connections between Madrid and Brussels

See here how frequent the connections between Madrid and Brussels are, during different times and days of the week.
Thursday is the busiest day, with more than 22 daily buses from Madrid to Brussels. Sunday has instead the fewest connections, with only 14 daily coaches between Madrid and Brussels.
The busiest time of the day is the Afternoon, with 57 buses from Madrid to Brussels, while Night sees the fewest connections between Madrid and Brussels, with 10 offers.

Facts about the bus from Madrid to Brussels

Compare all providers like FlixBus and BlaBlaCar Bus that travel 17 times every day by bus from Madrid to Brussels in one click! Book your bus ticket from Madrid to Brussels starting from $52!

Cheapest Bus $52
Fastest Bus 20h 55m
Earliest Bus 2:50 PM
Latest Bus 11:20 PM
Daily Bus Routes 17 Ø
Distance 818.4 miles
Bus Companies FlixBus and BlaBlaCar Bus

Cheapest bus connections from Madrid to Brussels

Every day, 17 buses from 2 bus companies leave Madrid for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/25/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
$55
Thursday 06/26
$64
Friday 06/27
$58
Saturday 06/28
Sunday 06/29
$60
Monday 06/30
$58
Tuesday 07/01
$52
Wednesday 07/02
Thursday 07/03
$65
Friday 07/04
$101
Saturday 07/05
Sunday 07/06
Monday 07/07
$90
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
$80
Saturday 07/12
$80
Sunday 07/13
Monday 07/14
Tuesday 07/15
Wednesday 07/16
Thursday 07/17
Friday 07/18
$82
Saturday 07/19

The cheapest time to travel from Madrid to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Brussels, for the next 30 days.
With a price starting from $52, Tuesday is the cheapest day for a bus from Madrid to Brussels. Thursday instead is the most expensive day with prices starting from $64.
Evening is the cheapest day time for bus tickets from Madrid to Brussels, with $52. Night is the most expensive time of the day with prices starting from $55.

How to save money travelling from Madrid to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Brussels are also emptier.

All bus stations and stops in Madrid and Brussels

In the map below, you can see where to find all bus stations in Madrid and Brussels.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Brussels? Compare all modes of transports from Madrid to Brussels.

Service and Comfort on the bus from Madrid to Brussels

Want to know which seat classes are available on the buses from Madrid to Brussels? Or which bus companies serve the route Madrid to Brussels? Below you will find answers to your questions.

FAQs about the Madrid to Brussels bus

How much does a Madrid Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $52 and takes 21h 15m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Madrid to Brussels?

This route is offered by 2 companies with a range of ticket prices between $52 and $164. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Madrid to Brussels each day?

Every day, the Madrid to Brussels bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Brussels take?

The fastest bus from Madrid to Brussels is offered by BlaBlaCar Bus and takes 20h 55m. Bus tickets for this connection cost $74. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Brussels?

The earliest bus arriving in Brussels from Madrid starts at 2:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Brussels?

The latest bus trip departing from Madrid for Brussels starts at 11:20 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Brussels route?

When traveling by bus from Madrid to Brussels, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Brussels?

You can check all the direct connections between Madrid and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Madrid to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Madrid to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Brussels

Here’s an overview of the most popular bus routes to Madrid and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Porto - Madrid Buses Porto - Madrid
Bus Cordoba - Madrid Bus Cordoba - Madrid
Buses from Salamanca (ES) to Madrid Buses from Salamanca (ES) to Madrid
Bus Alicante to Madrid Bus Alicante to Madrid
Bus to Brussels from Zurich Bus to Brussels from Zurich
Buses Prague - Brussels Buses Prague - Brussels
Bus to Brussels from Rotterdam Bus to Brussels from Rotterdam
Buses Vienna to Brussels Buses Vienna to Brussels
Popular Airport Shuttles to Madrid and to Brussels
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