Bus Madrid to Brussels: Compare prices and save money

Compare all timetables for the bus from Madrid to Brussels

Here is a selection of the cheapest bus trips from the schedule from Madrid to Brussels from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

tomorrow

Sunday

$49

Monday

Tuesday

$59

Wednesday

Thursday

$65

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	21h 55m	6:35 PM	Madrid	Sur Bus Station	4:30 PM	Brussels	Midi Bus Station	Economy	$49	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/7/2025 6:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/8/2025 4:30:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 21h 55m
BlaBlaCar Bus	22h 20m	10:30 PM	Madrid	Sur Bus Station	8:50 PM	Brussels	Midi Bus Station	Economy	$64	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/7/2025 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/8/2025 8:50:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 22h 20m
FlixBus	24h 5m	4:40 PM	Madrid	Sur Bus Station	4:45 PM	Brussels	North Station	Economy	$84	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/7/2025 4:40:00 PM to North Station, Brussels (Belgium) arriving at 12/8/2025 4:45:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 24h 5m
FlixBus	26h 10m	8:50 PM	Madrid	Sur Bus Station	11:00 PM	Brussels	North Station	Economy	$91	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/7/2025 8:50:00 PM to North Station, Brussels (Belgium) arriving at 12/8/2025 11:00:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 26h 10m
FlixBus	22h 55m	4:40 PM	Madrid	Sur Bus Station	3:35 PM	Brussels	Midi Bus Station	Economy	$91	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/7/2025 4:40:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/8/2025 3:35:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 22h 55m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 5m	3:45 PM	Madrid	Sur Bus Station	3:50 PM	Brussels	Midi Bus Station	Economy	$59	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 3:45:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/10/2025 3:50:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 24h 5m
FlixBus	23h 10m	4:40 PM	Madrid	Sur Bus Station	3:50 PM	Brussels	Midi Bus Station	Economy	$59	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 4:40:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/10/2025 3:50:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 23h 10m
FlixBus	24h 30m	3:45 PM	Madrid	Sur Bus Station	4:15 PM	Brussels	North Station	Economy	$59	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 3:45:00 PM to North Station, Brussels (Belgium) arriving at 12/10/2025 4:15:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 24h 30m
FlixBus	22h 30m	4:40 PM	Madrid	Sur Bus Station	3:10 PM	Brussels	North Station	Economy	$61	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 4:40:00 PM to North Station, Brussels (Belgium) arriving at 12/10/2025 3:10:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 22h 30m
FlixBus	24h 5m	8:25 PM	Madrid	Sur Bus Station	8:30 PM	Brussels	North Station	Economy	$61	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/9/2025 8:25:00 PM to North Station, Brussels (Belgium) arriving at 12/10/2025 8:30:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 24h 5m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 55m	4:40 PM	Madrid	Sur Bus Station	3:35 PM	Brussels	North Station	Economy	$65	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 4:40:00 PM to North Station, Brussels (Belgium) arriving at 12/12/2025 3:35:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 22h 55m
FlixBus	21h 50m	8:25 PM	Madrid	Sur Bus Station	6:15 PM	Brussels	North Station	Economy	$65	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 8:25:00 PM to North Station, Brussels (Belgium) arriving at 12/12/2025 6:15:00 PM. 50 Economy ticket for $65 per person are available. Travel duration is 21h 50m
FlixBus	23h 10m	4:40 PM	Madrid	Sur Bus Station	3:50 PM	Brussels	Midi Bus Station	Economy	$66	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 4:40:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/12/2025 3:50:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 23h 10m
FlixBus	23h 10m	2:50 PM	Madrid	Sur Bus Station	2:00 PM	Brussels	North Station	Economy	$67	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/12/2025 2:00:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 23h 10m
FlixBus	21h 55m	2:50 PM	Madrid	Sur Bus Station	12:45 PM	Brussels	Midi Bus Station	Economy	$68	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/11/2025 2:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/12/2025 12:45:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 21h 55m

Best Price Offer: The price for the cheapest bus from Madrid to Brussels is $49 on 12/7/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Madrid and Brussels

See here how frequent the connections between Madrid and Brussels are, during different times and days of the week.

Thursday is the busiest day, with more than 18 daily buses from Madrid to Brussels. Tuesday has instead the fewest connections, with only 10 daily coaches between Madrid and Brussels.

The busiest time of the day is the Afternoon, with 27 buses from Madrid to Brussels, while Evening sees the fewest connections between Madrid and Brussels, with 12 offers.

Facts about the bus from Madrid to Brussels

Compare all providers like FlixBus and BlaBlaCar Bus that travel 13 times every day by bus from Madrid to Brussels in one click! Book your bus ticket from Madrid to Brussels starting from $49!

Cheapest Bus	$49
Fastest Bus	21h 30m
Earliest Bus	2:50 PM
Latest Bus	8:50 PM
Daily Bus Routes	13 Ø
Distance	818.4 miles
Bus Companies	FlixBus and BlaBlaCar Bus

Cheapest bus connections from Madrid to Brussels

Every day, 13 buses from 2 bus companies leave Madrid for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

Saturday 12/06

Sunday 12/07

$49

Monday 12/08

Tuesday 12/09

$59

Wednesday 12/10

Thursday 12/11

$65

Friday 12/12

$68

Saturday 12/13

$73

Sunday 12/14

$56

Monday 12/15

Tuesday 12/16

$72

Wednesday 12/17

$68

Thursday 12/18

Friday 12/19

$97

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

$114

Thursday 12/25

$118

Friday 12/26

Saturday 12/27

The cheapest time to travel from Madrid to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Brussels, for the next 30 days.

With a price starting from $49, Sunday is the cheapest day for a bus from Madrid to Brussels. Thursday instead is the most expensive day with prices starting from $65.

Evening is the cheapest day time for bus tickets from Madrid to Brussels, with $49. Afternoon is the most expensive time of the day with prices starting from $59.

How to save money travelling from Madrid to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Brussels are also emptier.

Beloved bus companies from Madrid to Brussels

These are the most booked bus companies between Madrid to Brussels from our users.

FlixBus from Madrid to Brussels

Here you will find the key facts about the FlixBus bus route Madrid to Brussels:

Cheapest Price	$59
Fastest Bus	21h 30m
Earliest Bus	2:50 PM
Last Bus	8:50 PM
Daily Connections	12 Ø
Found on	12/4/2025

All bus stations and stops in Madrid and Brussels

In the map below, you can see where to find all bus stations in Madrid and Brussels.

Avenida de América Bus Station

Avenida de América 13

Bus Stop

Calle de Tiziano 40

Intercambiador de Moncloa

Calle de la Princesa 89n

Plaza de Castilla

Sur Bus Station

Calle de Méndez Álvaro 83

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

Central Station

City Tours

Rue du Marché Aux Herbes 82

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Brussels? Compare all modes of transports from Madrid to Brussels.

Service and Comfort on the bus from Madrid to Brussels

Want to know which seat classes are available on the buses from Madrid to Brussels? Or which bus companies serve the route Madrid to Brussels? Below you will find answers to your questions.

FAQs about the Madrid to Brussels bus

How much does a Madrid Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $49 and takes 21h 55m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Madrid to Brussels?

This route is offered by 2 companies with a range of ticket prices between $49 and $95. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Madrid to Brussels each day?

Every day, the Madrid to Brussels bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Brussels take?

The fastest bus from Madrid to Brussels is offered by FlixBus and takes 21h 30m. Bus tickets for this connection cost $95. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Brussels?

The earliest bus arriving in Brussels from Madrid starts at 2:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Brussels?

The latest bus trip departing from Madrid for Brussels starts at 8:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Brussels route?

When traveling by bus from Madrid to Brussels, passengers can travel with FlixBus and BlaBlaCar Bus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Brussels?

You can check all the direct connections between Madrid and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the Madrid to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Madrid to Brussels

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Brussels

Here’s an overview of the most popular bus routes to Madrid and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!