Bus from Madrid to Brussels from $56

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Compare all timetables for the bus from Madrid to Brussels

Here is a selection of the cheapest bus trips from the schedule from Madrid to Brussels from various bus operators like FlixBus for the next days.

today
tomorrow
$73
Wednesday
$69
Thursday
Friday
$138
Saturday
Sunday
$77

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 30m 3:45 PM Madrid Sur Bus Station 4:15 PM Brussels North Station  Economy $73
FlixBus 24h 5m 8:25 PM Madrid Sur Bus Station 8:30 PM Brussels North Station  Economy $73
FlixBus 24h 5m 3:45 PM Madrid Sur Bus Station 3:50 PM Brussels Midi Bus Station  Economy $73
FlixBus 23h 10m 4:40 PM Madrid Sur Bus Station 3:50 PM Brussels Midi Bus Station  Economy $74
FlixBus 29h 15m 8:25 PM Madrid Sur Bus Station 1:40 AM Brussels Midi Bus Station  Economy $74
  • Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than $9? You can find the corresponding connections below.
    • FlixBus
      23h 35m
      0
      2:50 PM
      Madrid
      Sur Bus Station
      12:15 AM
      Bordeaux
      Saint-Jean Bus Stop
      0
      FlixBus
      Economy
      $29
      • Waiting Time 1h 15m
    • INFOBUS
      12h 55m
      0
      1:30 AM
      Bordeaux
      Saint Jean Train Station
      2:25 PM
      Brussels
      Midi Bus Station
      0
      INFOBUS
      Economy
      $35
    Travel time is 0h 25m longer, but you will save $9

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 25m 8:25 PM Madrid Sur Bus Station 8:50 PM Brussels Midi Bus Station  Economy $69
FlixBus 24h 5m 8:25 PM Madrid Sur Bus Station 8:30 PM Brussels North Station  Economy $72
FlixBus 22h 55m 4:40 PM Madrid Sur Bus Station 3:35 PM Brussels North Station  Economy $73
FlixBus 23h 10m 2:50 PM Madrid Sur Bus Station 2:00 PM Brussels North Station  Economy $79
FlixBus 21h 55m 2:50 PM Madrid Sur Bus Station 12:45 PM Brussels Midi Bus Station  Economy $79

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 29h 5m 9:55 PM Madrid Sur Bus Station 3:00 AM Brussels North Station  Economy $138
FlixBus 26h 10m 8:50 PM Madrid Sur Bus Station 11:00 PM Brussels North Station  Economy $151
FlixBus 26h 40m 8:50 PM Madrid Sur Bus Station 11:30 PM Brussels Midi Bus Station  Economy $160
FlixBus 23h 10m 2:50 PM Madrid Sur Bus Station 2:00 PM Brussels North Station  Economy $175
FlixBus 22h 55m 4:40 PM Madrid Sur Bus Station 3:35 PM Brussels North Station  Economy $176
  • Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than $74? You can find the corresponding connections below.
    • FlixBus
      23h 35m
      0
      2:50 PM
      Madrid
      Sur Bus Station
      12:15 AM
      Bordeaux
      Saint-Jean Bus Stop
      0
      FlixBus
      Economy
      $29
      • Waiting Time 1h 15m
    • INFOBUS
      12h 55m
      0
      1:30 AM
      Bordeaux
      Saint Jean Train Station
      2:25 PM
      Brussels
      Midi Bus Station
      0
      INFOBUS
      Economy
      $35
    Travel time is 0h 40m longer, but you will save $74

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 21h 55m 2:50 PM Madrid Sur Bus Station 12:45 PM Brussels North Station  Economy $77
FlixBus 29h 5m 9:55 PM Madrid Sur Bus Station 3:00 AM Brussels North Station  Economy $85
FlixBus 26h 10m 8:50 PM Madrid Sur Bus Station 11:00 PM Brussels North Station  Economy $101
FlixBus 26h 40m 8:50 PM Madrid Sur Bus Station 11:30 PM Brussels Midi Bus Station  Economy $104
FlixBus 29h 30m 4:40 PM Madrid Sur Bus Station 10:10 PM Brussels Heysel  Economy $107
  • Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than $13? You can find the corresponding connections below.
    • FlixBus
      23h 35m
      0
      2:50 PM
      Madrid
      Sur Bus Station
      12:15 AM
      Bordeaux
      Saint-Jean Bus Stop
      0
      FlixBus
      Economy
      $29
      • Waiting Time 1h 15m
    • INFOBUS
      12h 55m
      0
      1:30 AM
      Bordeaux
      Saint Jean Train Station
      2:25 PM
      Brussels
      Midi Bus Station
      0
      INFOBUS
      Economy
      $35
    Travel time is 1h 40m longer, but you will save $13

Best Price Offer: The price for the cheapest bus from Madrid to Brussels is $56 on 12/14/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Madrid and Brussels

See here how frequent the connections between Madrid and Brussels are, during different times and days of the week.
Tuesday is the busiest day, with more than 12 daily buses from Madrid to Brussels. Wednesday has instead the fewest connections, with only 7 daily coaches between Madrid and Brussels.
The busiest time of the day is the Afternoon, with 23 buses from Madrid to Brussels, while Evening sees the fewest connections between Madrid and Brussels, with 16 offers.

Facts about the bus from Madrid to Brussels

Compare all providers like FlixBus that travel 9 times every day by bus from Madrid to Brussels in one click! Book your bus ticket from Madrid to Brussels starting from $56!

Cheapest Bus $56
Fastest Bus 21h 30m
Earliest Bus 2:50 PM
Latest Bus 9:55 PM
Daily Bus Routes 9 Ø
Distance 818.4 miles
Bus Companies FlixBus

Cheapest bus connections from Madrid to Brussels

Every day, 9 buses from 1 bus companies leave Madrid for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/15/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
$73
Wednesday 12/17
$69
Thursday 12/18
Friday 12/19
$138
Saturday 12/20
Sunday 12/21
$77
Monday 12/22
Tuesday 12/23
$64
Wednesday 12/24
$114
Thursday 12/25
$118
Friday 12/26
Saturday 12/27
$153
Sunday 12/28
$141
Monday 12/29
Tuesday 12/30
$123
Wednesday 12/31
Thursday 01/01
$150
Friday 01/02
$111
Saturday 01/03
$153
Sunday 01/04
$155
Monday 01/05
Tuesday 01/06
Wednesday 01/07
$102
Thursday 01/08
Friday 01/09
Saturday 01/10

The cheapest time to travel from Madrid to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Brussels, for the next 30 days.
With a price starting from $64, Tuesday is the cheapest day for a bus from Madrid to Brussels. Friday instead is the most expensive day with prices starting from $111.
Evening is the cheapest day time for bus tickets from Madrid to Brussels, with $69. Afternoon is the most expensive time of the day with prices starting from $73.

How to save money travelling from Madrid to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Madrid to Brussels are also emptier.

Beloved bus companies from Madrid to Brussels

These are the most booked bus companies between Madrid to Brussels from our users.

FlixBus from Madrid to Brussels

FlixBus

Here you will find the key facts about the FlixBus bus route Madrid to Brussels:

Cheapest Price $69
Fastest Bus 21h 30m
Earliest Bus 2:50 PM
Last Bus 9:55 PM
Daily Connections 9 Ø
Found on 12/12/2025

All bus stations and stops in Madrid and Brussels

In the map below, you can see where to find all bus stations in Madrid and Brussels.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Brussels? Compare all modes of transports from Madrid to Brussels.

Service and Comfort on the bus from Madrid to Brussels

Want to know which seat classes are available on the buses from Madrid to Brussels? Or which bus companies serve the route Madrid to Brussels? Below you will find answers to your questions.

FAQs about the Madrid to Brussels bus

How much does a Madrid Brussels bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $56 and takes 24h 25m to reach Brussels. Compare offers to save money!

How much could I save by comparing buses from Madrid to Brussels?

This route is offered by 1 companies with a range of ticket prices between $56 and $182. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Brussels.

On average, how many connections are available from Madrid to Brussels each day?

Every day, the Madrid to Brussels bus route is served by approximately 9 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Madrid to Brussels take?

The fastest bus from Madrid to Brussels is offered by FlixBus and takes 21h 30m. Bus tickets for this connection cost $181. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Madrid to Brussels?

The earliest bus arriving in Brussels from Madrid starts at 2:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Madrid to Brussels?

The latest bus trip departing from Madrid for Brussels starts at 9:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Madrid Brussels route?

When traveling by bus from Madrid to Brussels, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Madrid and Brussels?

You can check all the direct connections between Madrid and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Madrid to Brussels bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Madrid Brussels bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Madrid to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 9 daily trips between Madrid and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Madrid to Brussels?

Prices and availability for 9 trips between Madrid and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Madrid to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Brussels

Here’s an overview of the most popular bus routes to Madrid and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Barcelona - Madrid Buses Barcelona - Madrid
Buses Seville to Madrid Buses Seville to Madrid
Malaga to Madrid bus Malaga to Madrid bus
Buses Porto - Madrid Buses Porto - Madrid
Bus from London to Brussels Bus from London to Brussels
Bus Amsterdam - Brussels Bus Amsterdam - Brussels
Bruges (BE) to Brussels bus Bruges (BE) to Brussels bus
Buses Ghent - Brussels Buses Ghent - Brussels
Popular Airport Shuttles to Madrid and to Brussels
CheckMyBus › Buses in Spain › Bus to Madrid › Bus to Brussels

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