What is the best way to travel from Madrid to Brussels?
Looking for a trip? Compare all the available Buses, Carpool and Flights for the journey to Brussels from Madrid. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Madrid?
You can get to Brussels with just $64 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus29h 5m09:55 PMMadridSur Bus Station3:00 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 9:55:00 PM to North Station, Brussels (Belgium) arriving at 12/21/2025 3:00:00 AM. 50 Economy ticket for $138 per person are available. Travel duration is 29h 5m
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FlixBus26h 10m08:50 PMMadridSur Bus Station11:00 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 8:50:00 PM to North Station, Brussels (Belgium) arriving at 12/20/2025 11:00:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 26h 10m
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FlixBus26h 40m08:50 PMMadridSur Bus Station11:30 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 8:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/20/2025 11:30:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 26h 40m
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FlixBus23h 10m02:50 PMMadridSur Bus Station2:00 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/20/2025 2:00:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 23h 10m
Cheapest Buses Friday
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FlixBus21h 55m02:50 PMMadridSur Bus Station12:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/22/2025 12:45:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 21h 55m
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FlixBus29h 5m09:55 PMMadridSur Bus Station3:00 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 9:55:00 PM to North Station, Brussels (Belgium) arriving at 12/23/2025 3:00:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 29h 5m
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FlixBus21h 55m02:50 PMMadridSur Bus Station12:45 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 2:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/22/2025 12:45:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 21h 55m
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FlixBus26h 10m08:50 PMMadridSur Bus Station11:00 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 8:50:00 PM to North Station, Brussels (Belgium) arriving at 12/22/2025 11:00:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 26h 10m
Cheapest Buses Sunday
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FlixBus24h 30m03:45 PMMadridSur Bus Station4:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 3:45:00 PM to North Station, Brussels (Belgium) arriving at 12/24/2025 4:15:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 24h 30m
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FlixBus24h 5m03:45 PMMadridSur Bus Station3:50 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 3:45:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 3:50:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 24h 5m
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FlixBus29h 5m09:55 PMMadridSur Bus Station3:00 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 9:55:00 PM to North Station, Brussels (Belgium) arriving at 12/25/2025 3:00:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 29h 5m
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FlixBus21h 55m02:50 PMMadridSur Bus Station12:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/24/2025 12:45:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 21h 55m
Cheapest Buses Tuesday
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BlaBlaCar Bus21h 5m06:35 PMMadridSur Bus Station3:40 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 6:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 3:40:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 21h 5m
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BlaBlaCar Bus21h 15m010:30 PMMadridSur Bus Station7:45 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 7:45:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 21h 15m
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FlixBus22h 5m04:40 PMMadridSur Bus Station2:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 4:40:00 PM to North Station, Brussels (Belgium) arriving at 12/25/2025 2:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 5m
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FlixBus23h 10m02:50 PMMadridSur Bus Station2:00 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/25/2025 2:00:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 23h 10m
Cheapest Buses Wednesday
What are the fastest trips from Madrid to Brussels?
You can get to Brussels from Madrid in just 21h 5m with a Bus from BlaBlaCar Bus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus22h 55m04:40 PMMadridSur Bus Station3:35 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 4:40:00 PM to North Station, Brussels (Belgium) arriving at 12/20/2025 3:35:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 22h 55m
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FlixBus23h 10m02:50 PMMadridSur Bus Station2:00 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/20/2025 2:00:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 23h 10m
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FlixBus26h 10m08:50 PMMadridSur Bus Station11:00 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 8:50:00 PM to North Station, Brussels (Belgium) arriving at 12/20/2025 11:00:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 26h 10m
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FlixBus26h 40m08:50 PMMadridSur Bus Station11:30 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/19/2025 8:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/20/2025 11:30:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 26h 40m
Fastest Buses Friday
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FlixBus21h 55m02:50 PMMadridSur Bus Station12:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/22/2025 12:45:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 21h 55m
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FlixBus21h 55m02:50 PMMadridSur Bus Station12:45 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 2:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/22/2025 12:45:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 21h 55m
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FlixBus26h 10m08:50 PMMadridSur Bus Station11:00 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 8:50:00 PM to North Station, Brussels (Belgium) arriving at 12/22/2025 11:00:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 26h 10m
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FlixBus26h 40m08:50 PMMadridSur Bus Station11:30 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/21/2025 8:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/22/2025 11:30:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 26h 40m
Fastest Buses Sunday
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FlixBus21h 55m02:50 PMMadridSur Bus Station12:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 2:50:00 PM to North Station, Brussels (Belgium) arriving at 12/24/2025 12:45:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 21h 55m
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FlixBus21h 55m02:50 PMMadridSur Bus Station12:45 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 2:50:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 12:45:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 21h 55m
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FlixBus24h 5m03:45 PMMadridSur Bus Station3:50 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 3:45:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 3:50:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 24h 5m
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FlixBus24h 30m03:45 PMMadridSur Bus Station4:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/23/2025 3:45:00 PM to North Station, Brussels (Belgium) arriving at 12/24/2025 4:15:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 24h 30m
Fastest Buses Tuesday
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BlaBlaCar Bus21h 5m06:35 PMMadridSur Bus Station3:40 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 6:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 3:40:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 21h 5m
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BlaBlaCar Bus21h 15m010:30 PMMadridSur Bus Station7:45 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 7:45:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 21h 15m
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FlixBus22h 5m04:40 PMMadridSur Bus Station2:45 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 4:40:00 PM to North Station, Brussels (Belgium) arriving at 12/25/2025 2:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 5m
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FlixBus22h 55m04:40 PMMadridSur Bus Station3:35 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/24/2025 4:40:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 3:35:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 22h 55m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Madrid to Brussels
What are the most popular stations in Madrid and Brussels?
In Madrid, you will usually depart from Atocha Train Station, Chamartin Train Station or Sur Bus Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Madrid? With 5 connections between 2 Bus, Carpool and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Brussels, you can pay as low as $64 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from BlaBlaCar Bus: you will get to Brussels in just 21h 5m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Brussels are FlixBus and BlaBlaCar Bus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Saint-Gilles, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Brussels?
The most popular companies between Madrid and Brussels, are FlixBus and BlaBlaCar Bus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
All you need to know when you travel from Madrid to Brussels
Check all information on comfort and services on all modes of transports from Madrid to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Brussels
How can I reach Brussels from Madrid?
Every day, there are on average 5 connections between Bus, Carpool and Flight, with which you can get to Brussels from Madrid.
How far is Brussels from Madrid?
The distance between Madrid and Brussels is 818.4 miles.
What is the most ecofriendly mode of transport between Madrid and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 36 kgs of CO2, a train 46 kgs, a car 224 kgs, and a flight 324 kgs.
What is the cheapest mode of transport from Madrid to Brussels?
You can get to Brussels with just $64 by taking a Bus from FlixBus.
What is the fastest way to get from Madrid to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 21h 5m with a Bus from BlaBlaCar Bus.
More routes to Madrid and to Brussels
Looking for more options? Here you can see the most popular routes to Madrid and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- A Coruña to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Castellón de la Plana to Madrid
- Gandía to Madrid
- Huelva to Madrid
- León to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Molina de Aragón to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Brussels
- Aachen to Brussels
- Amiens to Brussels
- Basel to Brussels
- Berlin to Brussels
- Birmingham to Brussels
- Bordeaux to Brussels
- Bremen to Brussels
- Bruges (BE) to Brussels
- Dortmund to Brussels
- Dusseldorf to Brussels
- Frankfurt am Main to Brussels
- Ghent to Brussels
- Hamburg to Brussels
- Innsbruck to Brussels
- Le Mans to Brussels
- Leeds to Brussels
- Lille to Brussels
- Nantes to Brussels
- Newcastle upon Tyne to Brussels
- Nuremberg to Brussels
- Rotterdam to Brussels
- Salzburg to Brussels
- Sofia to Brussels
- Valencia to Brussels

