What is the best way to travel from Madrid to Brussels?
Looking for a trip? Compare all the available Flights and Buses for the journey to Brussels from Madrid. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Madrid?
You can get to Brussels with just $61 by taking a Flight from Ryanair, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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BlaBlaCar Bus22h 20m010:30 PMMadridSur Bus Station8:50 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/26/2026 8:50:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 22h 20m
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BlaBlaCar Bus20h 30m03:30 PMMadridSur Bus Station12:00 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 3:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/26/2026 12:00:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 20h 30m
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BlaBlaCar Bus20h 40m06:35 PMMadridSur Bus Station3:15 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 6:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/26/2026 3:15:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 20h 40m
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FlixBus22h 15m010:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 10:55:00 PM to North Station, Brussels (Belgium) arriving at 3/26/2026 9:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 22h 15m
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FlixBus22h 35m010:35 PMMadridSur Bus Station9:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 10:35:00 PM to North Station, Brussels (Belgium) arriving at 3/26/2026 9:10:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 22h 35m
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Ryanair2h 25m08:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 8:10:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/25/2026 10:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 2h 25m
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Aeronova7h 25m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/25/2026 2:30:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 7h 25m
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Iberia27h 15m04:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:15 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 4:00:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/26/2026 7:15:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 27h 15m
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Air Europa5h 15m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/25/2026 12:20:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 5h 15m
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Air Europa5h 15m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:20 PMBrussels AirportBrussels Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 7:05:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/25/2026 12:20:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 5h 15m
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Vueling Airlines13h 50m011:00 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport12:50 PMBrussels AirportBrussels Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 11:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/26/2026 12:50:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 13h 50m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Ryanair2h 30m05:50 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 5:50:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/26/2026 8:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 2h 30m
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Wizz Air9h 10m010:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 10:10:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/26/2026 7:20:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 10m
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Ryanair8h 10m012:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 12:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/26/2026 8:55:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 8h 10m
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Ryanair8h 10m012:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 PMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 12:45:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/26/2026 8:55:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 8h 10m
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Iberia12h 5m07:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:15 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 7:10:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/26/2026 7:15:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 12h 5m
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Wizz Air11h 30m09:25 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 9:25:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/27/2026 8:55:00 AM. 50 Economy ticket for $188 per person are available. Travel duration is 11h 30m
Cheapest Flights Thursday
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FlixBus22h 15m010:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 10:55:00 PM to North Station, Brussels (Belgium) arriving at 3/28/2026 9:10:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 22h 15m
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FlixBus22h 35m010:35 PMMadridSur Bus Station9:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:35:00 PM to North Station, Brussels (Belgium) arriving at 3/28/2026 9:10:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 22h 35m
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FlixBus26h 35m010:35 PMMadridSur Bus Station1:10 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/29/2026 1:10:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 26h 35m
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BlaBlaCar Bus20h 40m06:35 PMMadridSur Bus Station3:15 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 6:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2026 3:15:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 20h 40m
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BlaBlaCar Bus22h 20m010:30 PMMadridSur Bus Station8:50 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2026 8:50:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 22h 20m
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Ryanair14h 0m09:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport11:30 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 9:30:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/28/2026 11:30:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 14h 0m
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Ryanair26h 35m01:35 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport4:10 PMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 1:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/28/2026 4:10:00 PM. 50 Economy ticket for $186 per person are available. Travel duration is 26h 35m
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Vueling Airlines11h 25m09:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 AMBrussels AirportBrussels Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 9:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/28/2026 8:55:00 AM. 50 Economy ticket for $249 per person are available. Travel duration is 11h 25m
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Air Europa7h 5m07:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 7:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/27/2026 2:35:00 PM. 50 Economy ticket for $256 per person are available. Travel duration is 7h 5m
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Air Europa5h 0m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/27/2026 12:05:00 PM. 50 Economy ticket for $284 per person are available. Travel duration is 5h 0m
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Air Nostrum5h 15m07:20 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/27/2026 12:35:00 PM. 50 Economy ticket for $307 per person are available. Travel duration is 5h 15m
Cheapest Buses Friday
Cheapest Flights Friday
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BlaBlaCar Bus22h 20m010:30 PMMadridSur Bus Station8:50 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2026 8:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 22h 20m
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BlaBlaCar Bus20h 30m03:30 PMMadridSur Bus Station12:00 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 3:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2026 12:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 30m
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FlixBus26h 35m010:35 PMMadridSur Bus Station1:10 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 10:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/31/2026 1:10:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 26h 35m
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FlixBus22h 15m010:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:55:00 PM to North Station, Brussels (Belgium) arriving at 3/30/2026 9:10:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 15m
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FlixBus22h 35m010:35 PMMadridSur Bus Station9:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 10:35:00 PM to North Station, Brussels (Belgium) arriving at 3/30/2026 9:10:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 35m
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Aer Lingus22h 45m010:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Aer Lingus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:40:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/30/2026 9:25:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 22h 45m
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Aer Lingus11h 0m010:40 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:40 AMBrussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:40:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/30/2026 9:40:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 11h 0m
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Air Europa5h 0m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/29/2026 12:05:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 5h 0m
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Iberia Express8h 40m07:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T43:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Iberia Express goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 7:10:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/29/2026 3:50:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 8h 40m
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Skyscanner12h 35m010:25 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:00 AMBrussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/30/2026 11:00:00 AM. 50 Economy ticket for $120 per person are available. Travel duration is 12h 35m
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TAP Portugal12h 35m010:25 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport11:00 AMBrussels AirportBrussels Airport0EconomyA Flight from TAP Portugal goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/30/2026 11:00:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 12h 35m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from Madrid to Brussels?
You can get to Brussels from Madrid in just 2h 20m with a Flight from Ryanair. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Ryanair2h 20m07:40 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T410:00 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 7:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/25/2026 10:00:00 AM. 50 Economy ticket for $257 per person are available. Travel duration is 2h 20m
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Ryanair2h 25m08:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 8:10:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/25/2026 10:35:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 2h 25m
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Air Europa5h 15m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/25/2026 12:20:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 5h 15m
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Air Europa5h 15m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:20 PMBrussels AirportBrussels Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 7:05:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/25/2026 12:20:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 5h 15m
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Aeronova7h 25m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Aeronova goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/25/2026 2:30:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 7h 25m
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TAP Portugal8h 55m02:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:50 PMBrussels AirportBrussels Airport0EconomyA Flight from TAP Portugal goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 2:55:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/25/2026 11:50:00 PM. 50 Economy ticket for $286 per person are available. Travel duration is 8h 55m
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BlaBlaCar Bus20h 30m03:30 PMMadridSur Bus Station12:00 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 3:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/26/2026 12:00:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 20h 30m
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BlaBlaCar Bus20h 40m06:35 PMMadridSur Bus Station3:15 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 6:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/26/2026 3:15:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 20h 40m
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FlixBus22h 15m010:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/25/2026 10:55:00 PM to North Station, Brussels (Belgium) arriving at 3/26/2026 9:10:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 22h 15m
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BlaBlaCar Bus22h 20m010:30 PMMadridSur Bus Station8:50 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/26/2026 8:50:00 PM. 50 Economy ticket for $72 per person are available. Travel duration is 22h 20m
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FlixBus22h 35m010:35 PMMadridSur Bus Station9:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/25/2026 10:35:00 PM to North Station, Brussels (Belgium) arriving at 3/26/2026 9:10:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 22h 35m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Ryanair2h 30m05:50 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 5:50:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/26/2026 8:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 2h 30m
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Ryanair8h 10m012:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 12:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/26/2026 8:55:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 8h 10m
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Ryanair8h 10m012:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 PMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 12:45:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/26/2026 8:55:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 8h 10m
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Wizz Air9h 10m010:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 10:10:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/26/2026 7:20:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 9h 10m
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Wizz Air11h 30m09:25 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 9:25:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/27/2026 8:55:00 AM. 50 Economy ticket for $188 per person are available. Travel duration is 11h 30m
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Iberia12h 5m07:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:15 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/26/2026 7:10:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/26/2026 7:15:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 12h 5m
Fastest Flights Thursday
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Brussels Airlines2h 25m08:45 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T411:10 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 8:45:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/27/2026 11:10:00 PM. 50 Economy ticket for $360 per person are available. Travel duration is 2h 25m
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Air Europa5h 0m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/27/2026 12:05:00 PM. 50 Economy ticket for $284 per person are available. Travel duration is 5h 0m
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Air Nostrum5h 15m07:20 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/27/2026 12:35:00 PM. 50 Economy ticket for $307 per person are available. Travel duration is 5h 15m
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Air Europa7h 5m07:30 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T42:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 7:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/27/2026 2:35:00 PM. 50 Economy ticket for $256 per person are available. Travel duration is 7h 5m
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Air Europa7h 10m03:10 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport10:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Air Europa goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 3:10:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/27/2026 10:20:00 PM. 50 Economy ticket for $627 per person are available. Travel duration is 7h 10m
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Vueling Airlines11h 25m09:30 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport8:55 AMBrussels AirportBrussels Airport0EconomyA Flight from Vueling Airlines goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 9:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/28/2026 8:55:00 AM. 50 Economy ticket for $249 per person are available. Travel duration is 11h 25m
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BlaBlaCar Bus20h 40m06:35 PMMadridSur Bus Station3:15 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 6:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2026 3:15:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 20h 40m
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FlixBus22h 15m010:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/27/2026 10:55:00 PM to North Station, Brussels (Belgium) arriving at 3/28/2026 9:10:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 22h 15m
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BlaBlaCar Bus22h 20m010:30 PMMadridSur Bus Station8:50 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/28/2026 8:50:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 22h 20m
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FlixBus22h 35m010:35 PMMadridSur Bus Station9:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:35:00 PM to North Station, Brussels (Belgium) arriving at 3/28/2026 9:10:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 22h 35m
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FlixBus26h 35m010:35 PMMadridSur Bus Station1:10 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/27/2026 10:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/29/2026 1:10:00 AM. 50 Economy ticket for $149 per person are available. Travel duration is 26h 35m
Fastest Flights Friday
Fastest Buses Friday
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Air Europa5h 0m07:05 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Air Europa goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 7:05:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/29/2026 12:05:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 5h 0m
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Iberia5h 30m08:25 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T41:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Iberia goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 8:25:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/29/2026 1:55:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 5h 30m
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Air Nostrum5h 30m07:25 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T412:55 PMBrussels AirportBrussels Airport0EconomyA Flight from Air Nostrum goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 7:25:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/29/2026 12:55:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 5h 30m
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Iberia7h 40m07:25 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport3:05 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Iberia goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 7:25:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 3/29/2026 3:05:00 PM. 50 Economy ticket for $330 per person are available. Travel duration is 7h 40m
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Iberia Express8h 40m07:10 AMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T43:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Iberia Express goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 7:10:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/29/2026 3:50:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 8h 40m
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Wizz Air10h 40m08:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport7:35 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 8:55:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/30/2026 7:35:00 AM. 50 Economy ticket for $183 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus20h 30m03:30 PMMadridSur Bus Station12:00 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 3:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2026 12:00:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 20h 30m
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FlixBus22h 15m010:55 PMAdolfo Suárez Madrid-Barajas AirportMadrid Airport - T49:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 3/29/2026 10:55:00 PM to North Station, Brussels (Belgium) arriving at 3/30/2026 9:10:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 15m
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BlaBlaCar Bus22h 20m010:30 PMMadridSur Bus Station8:50 PMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 10:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/30/2026 8:50:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 22h 20m
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FlixBus22h 35m010:35 PMMadridSur Bus Station9:10 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 10:35:00 PM to North Station, Brussels (Belgium) arriving at 3/30/2026 9:10:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 22h 35m
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FlixBus26h 35m010:35 PMMadridSur Bus Station1:10 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 3/29/2026 10:35:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/31/2026 1:10:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 26h 35m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Madrid to Brussels
What are the most popular stations in Madrid and Brussels?
In Madrid, you will usually depart from Atocha Train Station, Chamartin Train Station or Sur Bus Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Madrid? With 15 connections between 3 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Madrid and Brussels, you can pay as low as $61 with a Flight from Ryanair.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Brussels in just 2h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Madrid and Brussels are Iberia, FlixBus and Air Europa, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Madrid and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Delicias or to Saint-Gilles, and look at flights from Adolfo Suárez Madrid-Barajas Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Madrid to Brussels?
The most popular companies between Madrid and Brussels, are Iberia, FlixBus and Air Europa. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Airlines: Iberia, Air Europa, Ryanair and 11 more.
All you need to know when you travel from Madrid to Brussels
Check all information on comfort and services on all modes of transports from Madrid to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Madrid to Brussels
How can I reach Brussels from Madrid?
Every day, there are on average 15 connections between Flight and Bus, with which you can get to Brussels from Madrid.
How far is Brussels from Madrid?
The distance between Madrid and Brussels is 818.4 miles.
What is the most ecofriendly mode of transport between Madrid and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 36 kgs of CO2, a train 46 kgs, a car 224 kgs, and a flight 324 kgs.
What is the cheapest mode of transport from Madrid to Brussels?
You can get to Brussels with just $61 by taking a Flight from Ryanair.
What is the fastest way to get from Madrid to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 2h 20m with a Flight from Ryanair.
More routes to Madrid and to Brussels
Looking for more options? Here you can see the most popular routes to Madrid and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Madrid
- Algeciras to Madrid
- Alicante to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Benidorm to Madrid
- Bilbao to Madrid
- Castellón de la Plana to Madrid
- Cordoba to Madrid
- Huelva to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Marbella to Madrid
- Mérida to Madrid
- Ourense to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Sebastian to Madrid
- Santiago de Compostela to Madrid
- Segovia to Madrid
- Seville to Madrid
- Toulouse to Madrid
- Valencia to Madrid
- Vigo to Madrid
- Trips to Brussels
- Berlin to Brussels
- Bern to Brussels
- Birmingham to Brussels
- Bruges (BE) to Brussels
- Cologne to Brussels
- Dusseldorf to Brussels
- Edinburgh to Brussels
- Essen to Brussels
- Frankfurt am Main to Brussels
- Ghent to Brussels
- Girona to Brussels
- Glasgow to Brussels
- Graz to Brussels
- Hamburg to Brussels
- Leeds to Brussels
- Lille to Brussels
- Manchester to Brussels
- Mannheim to Brussels
- Newcastle upon Tyne to Brussels
- Paris Charles de Gaulle Airport to Brussels
- Porto to Brussels
- Rotterdam to Brussels
- Toulouse to Brussels
- Zagreb to Brussels
