How to get from Prague to Brussels

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What is the best way to travel from Prague to Brussels?

Looking for a trip? Compare all the available Trains, Flights and Buses for the journey to Brussels from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
Flight is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
13h 20m
$50
$83
46
Flight
1h 30m
$17
$216
123

What is the cheapest way to reach Brussels from Prague?

You can get to Brussels with just $17 by taking a Flight from Ryanair, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Tuesday
from $62
Wednesday
from $17
Thursday
from $37
Friday
from $30
Saturday
from $62
Sunday
from $70
Monday
from $44

    Cheapest Buses Tuesday

  • FlixBus
    16h 10m
    0
    9:45 PM
    Prague Airport
    Prague Airport - T1/2
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    15h 35m
    0
    8:50 AM
    Prague Airport
    Prague Airport - T1/2
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $64
  • FlixBus
    18h 0m
    0
    1:20 PM
    Prague Airport
    Prague Airport - T1/2
    7:20 AM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $64
  • European Sleeper
    16h 30m
    0
    6:00 PM
    Prague
    Wilsonova Bus Station
    10:30 AM
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    $245
  • Cheapest Flights Tuesday

  • Skyscanner
    23h 50m
    0
    1:00 PM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Skyscanner
    Economy
    from $155
  • Ryanair
    22h 45m
    0
    2:05 PM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from $156
  • Buzz
    27h 5m
    0
    9:45 AM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from $170
  • Wizz Air
    28h 5m
    0
    8:45 AM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Wizz Air
    Economy
    from $180

    Cheapest Flights Wednesday

  • Ryanair
    1h 30m
    0
    9:25 PM
    Prague Airport
    Prague Airport - T1/2
    10:55 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $17
  • Brussels Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport - T1/2
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $97
  • Brussels Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $109
  • Brussels Airlines
    1h 30m
    0
    6:50 AM
    Prague Airport
    Prague Airport - T1/2
    8:20 AM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $205
  • Cheapest Buses Wednesday

  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $63
  • FlixBus
    17h 0m
    0
    1:45 AM
    Prague
    Wilsonova Bus Station
    6:45 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $64

    Cheapest Flights Thursday

  • Ryanair
    1h 30m
    0
    2:35 PM
    Prague Airport
    Prague Airport - T1/2
    4:05 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $37
  • Smartwings
    1h 30m
    0
    6:40 AM
    Prague Airport
    Prague Airport - T1/2
    8:10 AM
    Brussels Airport
    Brussels Airport
    0
    Smartwings
    Economy
    from $96
  • Smartwings
    1h 30m
    0
    6:40 AM
    Prague Airport
    Prague Airport
    8:10 AM
    Brussels Airport
    Brussels Airport
    0
    Smartwings
    Economy
    from $104
  • Brussels Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport - T1/2
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $166
  • Cheapest Buses Thursday

  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • European Sleeper
    15h 27m
    0
    6:00 PM
    Prague
    Wilsonova Bus Station
    9:27 AM
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    $280

    Cheapest Flights Friday

  • Ryanair
    1h 30m
    0
    9:25 PM
    Prague Airport
    Prague Airport - T1/2
    10:55 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $30
  • Buzz
    5h 25m
    0
    6:10 AM
    Prague Airport
    Prague Airport - T1/2
    11:35 AM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Buzz
    Economy
    from $111
  • EasyJet Airline
    11h 40m
    0
    9:55 PM
    Prague Airport
    Prague Airport
    9:35 AM
    Brussels Airport
    Brussels Airport
    0
    EasyJet Airline
    Economy
    from $123
  • Skyscanner
    10h 30m
    0
    8:05 AM
    Prague Airport
    Prague Airport - T1/2
    6:35 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Skyscanner
    Economy
    from $142
  • Cheapest Buses Friday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $63
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $63
  • FlixBus
    14h 50m
    0
    11:05 PM
    Prague
    ÚAN Florenc
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $63

    Cheapest Buses Saturday

  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    13h 20m
    0
    10:35 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    17h 0m
    0
    1:45 AM
    Prague
    Wilsonova Bus Station
    6:45 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $65
  • Cheapest Flights Saturday

  • Brussels Airlines
    1h 30m
    0
    6:50 AM
    Prague Airport
    Prague Airport
    8:20 AM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $184
  • Smartwings
    18h 35m
    0
    6:00 PM
    Prague Airport
    Prague Airport
    12:35 PM
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from $239
  • Brussels Airlines
    1h 30m
    0
    11:50 AM
    Prague Airport
    Prague Airport
    1:20 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $271
  • Smartwings
    14h 40m
    0
    6:00 AM
    Prague Airport
    Prague Airport
    8:40 PM
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from $411

    Cheapest Flights Sunday

  • Ryanair
    9h 5m
    0
    6:15 AM
    Prague Airport
    Prague Airport - T1/2
    3:20 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $70
  • Aegean Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport - T1/2
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Aegean Airlines
    Economy
    from $370
  • Brussels Airlines
    1h 30m
    0
    9:15 PM
    Prague Airport
    Prague Airport
    10:45 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $395
  • Smartwings
    27h 30m
    0
    5:20 PM
    Prague Airport
    Prague Airport
    8:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from $420
  • Cheapest Buses Sunday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $74
  • FlixBus
    14h 35m
    0
    9:50 AM
    Prague Airport
    Prague Airport - T1/2
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $78
  • FlixBus
    18h 15m
    0
    11:50 PM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $81
  • European Sleeper
    15h 27m
    0
    6:00 PM
    Prague
    Wilsonova Bus Station
    9:27 AM
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    $349

    Cheapest Flights Monday

  • Ryanair
    1h 30m
    0
    3:40 PM
    Prague Airport
    Prague Airport - T1/2
    5:10 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $44
  • Brussels Airlines
    1h 30m
    0
    6:50 AM
    Prague Airport
    Prague Airport
    8:20 AM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $226
  • Skyscanner
    24h 25m
    0
    1:30 PM
    Prague Airport
    Prague Airport - T1/2
    1:55 PM
    Antwerp Airport
    Antwerp Airport
    0
    Skyscanner
    Economy
    from $234
  • LC Perú
    28h 30m
    0
    9:25 AM
    Prague Airport
    Prague Airport - T1/2
    1:55 PM
    Antwerp Airport
    Antwerp Airport
    0
    LC Perú
    Economy
    from $245
  • Cheapest Buses Monday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $50
  • FlixBus
    14h 50m
    0
    11:05 PM
    Prague
    ÚAN Florenc
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $52
  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $53

What are the fastest trips from Prague to Brussels?

You can get to Brussels from Prague in just 1h 30m with a Flight from Ryanair. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Tuesday
from 15h 35m
Wednesday
from 1h 30m
Thursday
from 1h 30m
Friday
from 1h 30m
Saturday
from 1h 30m
Sunday
from 1h 30m
Monday
from 1h 30m

    Fastest Buses Tuesday

  • FlixBus
    15h 35m
    0
    8:50 AM
    Prague Airport
    Prague Airport - T1/2
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $64
  • FlixBus
    16h 10m
    0
    9:45 PM
    Prague Airport
    Prague Airport - T1/2
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $62
  • European Sleeper
    16h 30m
    0
    6:00 PM
    Prague
    Wilsonova Bus Station
    10:30 AM
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    $245
  • FlixBus
    18h 0m
    0
    1:20 PM
    Prague Airport
    Prague Airport - T1/2
    7:20 AM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $64
  • Fastest Flights Tuesday

  • Ryanair
    22h 45m
    0
    2:05 PM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Ryanair
    Economy
    from $156
  • Skyscanner
    23h 50m
    0
    1:00 PM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Skyscanner
    Economy
    from $155
  • Vueling Airlines
    26h 15m
    0
    10:35 AM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Vueling Airlines
    Economy
    from $187
  • Buzz
    27h 5m
    0
    9:45 AM
    Prague Airport
    Prague Airport - T1/2
    12:50 PM
    Antwerp Airport
    Antwerp Airport
    0
    Buzz
    Economy
    from $170

    Fastest Flights Wednesday

  • Ryanair
    1h 30m
    0
    9:25 PM
    Prague Airport
    Prague Airport - T1/2
    10:55 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $17
  • Brussels Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport - T1/2
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $97
  • Brussels Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $109
  • Brussels Airlines
    1h 30m
    0
    6:50 AM
    Prague Airport
    Prague Airport - T1/2
    8:20 AM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $205
  • Fastest Buses Wednesday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $63
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    15h 30m
    0
    6:00 PM
    Prague
    ÚAN Florenc
    9:30 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $64

    Fastest Flights Thursday

  • Ryanair
    1h 30m
    0
    2:35 PM
    Prague Airport
    Prague Airport - T1/2
    4:05 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $37
  • Smartwings
    1h 30m
    0
    6:40 AM
    Prague Airport
    Prague Airport - T1/2
    8:10 AM
    Brussels Airport
    Brussels Airport
    0
    Smartwings
    Economy
    from $96
  • Smartwings
    1h 30m
    0
    6:40 AM
    Prague Airport
    Prague Airport
    8:10 AM
    Brussels Airport
    Brussels Airport
    0
    Smartwings
    Economy
    from $104
  • Brussels Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport - T1/2
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $166
  • Fastest Buses Thursday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $55
  • European Sleeper
    15h 27m
    0
    6:00 PM
    Prague
    Wilsonova Bus Station
    9:27 AM
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    $280

    Fastest Flights Friday

  • Ryanair
    1h 30m
    0
    9:25 PM
    Prague Airport
    Prague Airport - T1/2
    10:55 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $30
  • Buzz
    5h 25m
    0
    6:10 AM
    Prague Airport
    Prague Airport - T1/2
    11:35 AM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Buzz
    Economy
    from $111
  • R Airlines
    5h 25m
    0
    10:05 AM
    Prague Airport
    Prague Airport - T1/2
    3:30 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    R Airlines
    Economy
    from $159
  • Skyscanner
    10h 30m
    0
    8:05 AM
    Prague Airport
    Prague Airport - T1/2
    6:35 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Skyscanner
    Economy
    from $142
  • Fastest Buses Friday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $63
  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $63
  • FlixBus
    14h 50m
    0
    11:05 PM
    Prague
    ÚAN Florenc
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $63

    Fastest Flights Saturday

  • Brussels Airlines
    1h 30m
    0
    6:50 AM
    Prague Airport
    Prague Airport
    8:20 AM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $184
  • Brussels Airlines
    1h 30m
    0
    11:50 AM
    Prague Airport
    Prague Airport
    1:20 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $271
  • Smartwings
    14h 40m
    0
    6:00 AM
    Prague Airport
    Prague Airport
    8:40 PM
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from $411
  • Smartwings
    18h 35m
    0
    6:00 PM
    Prague Airport
    Prague Airport
    12:35 PM
    Antwerp Airport
    Antwerp Airport
    0
    Smartwings
    Economy
    from $239
  • Fastest Buses Saturday

  • FlixBus
    13h 20m
    0
    10:35 AM
    Prague
    ÚAN Florenc
    11:55 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $62
  • FlixBus
    16h 0m
    0
    5:30 PM
    Prague
    Wilsonova Bus Station
    9:30 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $65

    Fastest Flights Sunday

  • Aegean Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport - T1/2
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Aegean Airlines
    Economy
    from $370
  • Brussels Airlines
    1h 30m
    0
    9:15 PM
    Prague Airport
    Prague Airport
    10:45 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $395
  • Brussels Airlines
    1h 30m
    0
    6:45 PM
    Prague Airport
    Prague Airport
    8:15 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $483
  • Ryanair
    9h 5m
    0
    6:15 AM
    Prague Airport
    Prague Airport - T1/2
    3:20 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $70
  • Fastest Buses Sunday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $74
  • FlixBus
    14h 35m
    0
    9:50 AM
    Prague Airport
    Prague Airport - T1/2
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $78
  • European Sleeper
    15h 27m
    0
    6:00 PM
    Prague
    Wilsonova Bus Station
    9:27 AM
    Brussels
    Midi Bus Station
    0
    European Sleeper
    Economy
    $349
  • FlixBus
    18h 15m
    0
    11:50 PM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $81

    Fastest Flights Monday

  • Ryanair
    1h 30m
    0
    3:40 PM
    Prague Airport
    Prague Airport - T1/2
    5:10 PM
    Brussels South Charleroi Airport
    Brussels South Charleroi Airport
    0
    Ryanair
    Economy
    from $44
  • Brussels Airlines
    1h 30m
    0
    6:50 AM
    Prague Airport
    Prague Airport
    8:20 AM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $226
  • Brussels Airlines
    1h 30m
    0
    11:50 AM
    Prague Airport
    Prague Airport
    1:20 PM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $273
  • Brussels Airlines
    1h 30m
    0
    6:50 AM
    Prague Airport
    Prague Airport - T1/2
    8:20 AM
    Brussels Airport
    Brussels Airport
    0
    Brussels Airlines
    Economy
    from $364
  • Fastest Buses Monday

  • FlixBus
    13h 20m
    0
    11:05 AM
    Prague
    ÚAN Florenc
    12:25 AM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $50
  • FlixBus
    13h 55m
    0
    4:10 AM
    Prague
    Na Knížecí Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    14h 15m
    0
    3:50 AM
    Prague
    Wilsonova Bus Station
    6:05 PM
    Brussels
    North Station
    0
    FlixBus
    Economy
    $53
  • FlixBus
    14h 50m
    0
    11:05 PM
    Prague
    ÚAN Florenc
    1:55 PM
    Brussels
    Midi Bus Station
    0
    FlixBus
    Economy
    $52
Here you will find all operators and timetables for a Bus from Prague to Brussels

What are the most popular stations in Prague and Brussels?

In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Brussels from Prague? With 13 connections between 3 Train, Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Brussels, you can pay as low as $17 with a Flight from Ryanair.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Brussels in just 1h 30m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Brussels are FlixBus, Brussels Airlines and Ryanair, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Prague and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Saint-Gilles, and look at flights from Prague Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Prague to Brussels?

The most popular companies between Prague and Brussels, are FlixBus, Brussels Airlines and Ryanair. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: FlixBus and European Sleeper

Airlines: Brussels Airlines, Ryanair, Smartwings and 11 more.

All you need to know when you travel from Prague to Brussels

Check all information on comfort and services on all modes of transports from Prague to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Prague to Brussels

How can I reach Brussels from Prague?

Every day, there are on average 13 connections between Train, Flight and Bus, with which you can get to Brussels from Prague.

How far is Brussels from Prague?

The distance between Prague and Brussels is 446.6 miles.

What is the most ecofriendly mode of transport between Prague and Brussels?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.

What is the cheapest mode of transport from Prague to Brussels?

You can get to Brussels with just $17 by taking a Flight from Ryanair.

What is the fastest way to get from Prague to Brussels?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 30m with a Flight from Ryanair.

More routes to Prague and to Brussels

Looking for more options? Here you can see the most popular routes to Prague and to Brussels. Simply click on a connection, and you’ll find all the details about the route!

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