What is the best way to travel from Prague to Brussels?
Looking for a trip? Compare all the available Flights and Buses for the journey to Brussels from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Prague?
You can get to Brussels with just $46 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/6/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 12:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 20m
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FlixBus17h 45m010:45 PMPrague AirportPrague Airport - T1/24:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/6/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/7/2026 4:30:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 17h 45m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/6/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/6/2026 6:05:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/6/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/6/2026 6:05:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 13h 55m
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FlixBus15h 35m08:50 AMPrague AirportPrague Airport - T1/212:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/6/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 12:25:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 15h 35m
Cheapest Buses Friday
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Buzz1h 30m02:35 PMPrague AirportPrague Airport - T1/24:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 2:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 4:05:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 30m
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Smartwings1h 30m06:40 AMPrague AirportPrague Airport - T1/28:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 6:40:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/7/2026 8:10:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 1h 30m
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Skyscanner6h 50m02:45 PMPrague AirportPrague Airport - T1/29:35 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 2:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 9:35:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 6h 50m
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Skyscanner5h 30m09:20 AMPrague AirportPrague Airport - T1/22:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 9:20:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 2:50:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 5h 30m
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Ryanair11h 5m010:00 PMPrague AirportPrague Airport - T1/29:05 AMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 10:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/8/2026 9:05:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 11h 5m
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Ryanair5h 0m03:45 PMPrague AirportPrague Airport - T1/28:45 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 3:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 8:45:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 5h 0m
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FlixBus13h 20m010:35 AMPragueÚAN Florenc11:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/7/2026 10:35:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 11:55:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 13h 20m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/7/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/7/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m08:50 AMPrague AirportPrague Airport - T1/211:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 11:55:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 15h 5m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/7/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/8/2026 7:20:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 15h 5m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/8/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/8/2026 6:05:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/8/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/8/2026 6:05:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 13h 55m
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FlixBus17h 45m010:45 PMPrague AirportPrague Airport - T1/24:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/9/2026 4:30:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 17h 45m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/8/2026 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/9/2026 9:27:00 AM. 50 Economy ticket for $849 per person are available. Travel duration is 15h 27m
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Smartwings21h 15m04:30 PMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 4:30:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 21h 15m
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Smartwings31h 45m06:00 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 31h 45m
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Ryanair18h 15m07:30 PMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 7:30:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 18h 15m
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Ryanair26h 40m011:05 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 11:05:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 26h 40m
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Bringer Air Cargo Taxi Aereo29h 30m08:15 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 8:15:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 29h 30m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/9/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/9/2026 6:05:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/9/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/9/2026 6:05:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 13h 55m
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/9/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/10/2026 12:25:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/9/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/10/2026 7:20:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 15h 5m
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FlixBus19h 30m010:45 PMPrague AirportPrague Airport - T1/26:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/9/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/10/2026 6:15:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 19h 30m
Cheapest Buses Monday
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/10/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/11/2026 12:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/10/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/11/2026 7:20:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m08:50 AMPrague AirportPrague Airport - T1/212:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/11/2026 12:25:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 15h 35m
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European Sleeper16h 30m06:00 PMPragueWilsonova Bus Station10:30 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/10/2026 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/11/2026 10:30:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 16h 30m
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EasyJet Airline40h 55m08:50 PMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 8:50:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/12/2026 1:45:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 40h 55m
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Ryanair30h 40m011:35 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 11:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 30h 40m
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LC Perú32h 50m09:25 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 9:25:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 32h 50m
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Buzz36h 15m06:00 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $278 per person are available. Travel duration is 36h 15m
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Smartwings30h 25m011:50 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 11:50:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $329 per person are available. Travel duration is 30h 25m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/11/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 12:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 13h 20m
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FlixBus15h 35m08:50 AMPrague AirportPrague Airport - T1/212:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/11/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 12:25:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 35m
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FlixBus20h 0m011:20 AMPrague AirportPrague Airport - T1/27:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/11/2026 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 2/12/2026 7:20:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 20h 0m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/11/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/12/2026 7:20:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 15h 5m
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FlixBus17h 45m010:45 PMPrague AirportPrague Airport - T1/24:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/11/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/12/2026 4:30:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 17h 45m
Cheapest Buses Wednesday
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/12/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 6:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/12/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 6:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/12/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/13/2026 7:20:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 15h 5m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/12/2026 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/13/2026 9:27:00 AM. 50 Economy ticket for $542 per person are available. Travel duration is 15h 27m
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Smartwings7h 45m06:00 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/12/2026 1:45:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 7h 45m
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Buzz30h 5m04:15 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 4:15:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 30h 5m
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Transavia France25h 40m08:40 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Transavia France goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 8:40:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 25h 40m
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Vueling Airlines25h 10m09:10 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 9:10:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 25h 10m
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Ryanair29h 50m04:30 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 4:30:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $273 per person are available. Travel duration is 29h 50m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Prague to Brussels?
You can get to Brussels from Prague in just 1h 30m with a Flight from Buzz. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/6/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 12:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/6/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/6/2026 6:05:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/6/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/6/2026 6:05:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 15m
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FlixBus15h 35m08:50 AMPrague AirportPrague Airport - T1/212:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/6/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 12:25:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 15h 35m
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FlixBus17h 45m010:45 PMPrague AirportPrague Airport - T1/24:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/6/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/7/2026 4:30:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 17h 45m
Fastest Buses Friday
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Buzz1h 30m02:35 PMPrague AirportPrague Airport - T1/24:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 2:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 4:05:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 1h 30m
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Smartwings1h 30m06:40 AMPrague AirportPrague Airport - T1/28:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 6:40:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/7/2026 8:10:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 1h 30m
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Ryanair5h 0m03:45 PMPrague AirportPrague Airport - T1/28:45 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 3:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 8:45:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 5h 0m
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Skyscanner5h 30m09:20 AMPrague AirportPrague Airport - T1/22:50 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 9:20:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 2:50:00 PM. 50 Economy ticket for $75 per person are available. Travel duration is 5h 30m
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Skyscanner6h 50m02:45 PMPrague AirportPrague Airport - T1/29:35 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 2:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 9:35:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 6h 50m
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Ryanair11h 5m010:00 PMPrague AirportPrague Airport - T1/29:05 AMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 10:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/8/2026 9:05:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 11h 5m
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FlixBus13h 20m010:35 AMPragueÚAN Florenc11:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/7/2026 10:35:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 11:55:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/7/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/7/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $59 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m08:50 AMPrague AirportPrague Airport - T1/211:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/7/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 11:55:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 15h 5m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/7/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/8/2026 7:20:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 15h 5m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/8/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/8/2026 6:05:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/8/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/8/2026 6:05:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 14h 15m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/8/2026 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/9/2026 9:27:00 AM. 50 Economy ticket for $849 per person are available. Travel duration is 15h 27m
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FlixBus17h 45m010:45 PMPrague AirportPrague Airport - T1/24:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/9/2026 4:30:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 17h 45m
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Ryanair18h 15m07:30 PMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 7:30:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 18h 15m
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Smartwings21h 15m04:30 PMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 4:30:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 21h 15m
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Ryanair26h 40m011:05 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 11:05:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $218 per person are available. Travel duration is 26h 40m
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Bringer Air Cargo Taxi Aereo29h 30m08:15 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Bringer Air Cargo Taxi Aereo goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 8:15:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 29h 30m
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Smartwings31h 45m06:00 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/8/2026 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/9/2026 1:45:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 31h 45m
Fastest Buses Sunday
Fastest Flights Sunday
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/9/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/10/2026 12:25:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/9/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/9/2026 6:05:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/9/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/9/2026 6:05:00 PM. 50 Economy ticket for $54 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/9/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/10/2026 7:20:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 15h 5m
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FlixBus19h 30m010:45 PMPrague AirportPrague Airport - T1/26:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/9/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/10/2026 6:15:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 19h 30m
Fastest Buses Monday
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/10/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/11/2026 12:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/10/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/11/2026 7:20:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m08:50 AMPrague AirportPrague Airport - T1/212:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/11/2026 12:25:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 15h 35m
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European Sleeper16h 30m06:00 PMPragueWilsonova Bus Station10:30 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/10/2026 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/11/2026 10:30:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 16h 30m
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Smartwings30h 25m011:50 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 11:50:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $329 per person are available. Travel duration is 30h 25m
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Ryanair30h 40m011:35 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 11:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 30h 40m
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LC Perú32h 50m09:25 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 9:25:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $260 per person are available. Travel duration is 32h 50m
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Buzz36h 15m06:00 AMPrague AirportPrague Airport - T1/26:15 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/11/2026 6:15:00 PM. 50 Economy ticket for $278 per person are available. Travel duration is 36h 15m
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EasyJet Airline40h 55m08:50 PMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/10/2026 8:50:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/12/2026 1:45:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 40h 55m
Fastest Buses Tuesday
Fastest Flights Tuesday
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/11/2026 11:05:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 12:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/11/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/12/2026 7:20:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 15h 5m
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FlixBus15h 35m08:50 AMPrague AirportPrague Airport - T1/212:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/11/2026 8:50:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 12:25:00 AM. 50 Economy ticket for $47 per person are available. Travel duration is 15h 35m
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FlixBus17h 45m010:45 PMPrague AirportPrague Airport - T1/24:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/11/2026 10:45:00 PM to North Station, Brussels (Belgium) arriving at 2/12/2026 4:30:00 PM. 50 Economy ticket for $51 per person are available. Travel duration is 17h 45m
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FlixBus20h 0m011:20 AMPrague AirportPrague Airport - T1/27:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/11/2026 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 2/12/2026 7:20:00 AM. 50 Economy ticket for $48 per person are available. Travel duration is 20h 0m
Fastest Buses Wednesday
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Smartwings7h 45m06:00 AMPrague AirportPrague Airport - T1/21:45 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 6:00:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/12/2026 1:45:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 7h 45m
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Vueling Airlines25h 10m09:10 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 9:10:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $247 per person are available. Travel duration is 25h 10m
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Transavia France25h 40m08:40 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Transavia France goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 8:40:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $244 per person are available. Travel duration is 25h 40m
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Ryanair29h 50m04:30 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 4:30:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $273 per person are available. Travel duration is 29h 50m
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Buzz30h 5m04:15 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 2/12/2026 4:15:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/13/2026 10:20:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 30h 5m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 2/12/2026 4:10:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 6:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/12/2026 3:50:00 AM to North Station, Brussels (Belgium) arriving at 2/12/2026 6:05:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 2/12/2026 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/13/2026 7:20:00 AM. 50 Economy ticket for $51 per person are available. Travel duration is 15h 5m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 2/12/2026 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/13/2026 9:27:00 AM. 50 Economy ticket for $542 per person are available. Travel duration is 15h 27m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Prague to Brussels
What are the most popular stations in Prague and Brussels?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Prague? With 8 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Brussels, you can pay as low as $46 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Buzz: you will get to Brussels in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Brussels are FlixBus, Ryanair and Smartwings, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Saint-Gilles, and look at flights from Prague Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Brussels?
The most popular companies between Prague and Brussels, are FlixBus, Ryanair and Smartwings. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and European Sleeper
Airlines: Ryanair, Smartwings, Buzz and 9 more.
All you need to know when you travel from Prague to Brussels
Check all information on comfort and services on all modes of transports from Prague to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Brussels
How can I reach Brussels from Prague?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Brussels from Prague.
How far is Brussels from Prague?
The distance between Prague and Brussels is 446.6 miles.
What is the most ecofriendly mode of transport between Prague and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Prague to Brussels?
You can get to Brussels with just $46 by taking a Bus from FlixBus.
What is the fastest way to get from Prague to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 30m with a Flight from Buzz.
More routes to Prague and to Brussels
Looking for more options? Here you can see the most popular routes to Prague and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bratislava to Prague
- Brno to Prague
- Budapest to Prague
- Cheb to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Leipzig to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Regensburg to Prague
- Třebíč to Prague
- Venice to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Brussels
- Basel to Brussels
- Beauvais to Brussels
- Berlin to Brussels
- Birmingham to Brussels
- Bordeaux to Brussels
- Brussels South Charleroi Airport to Brussels
- Dortmund to Brussels
- Dusseldorf to Brussels
- Erfurt to Brussels
- Essen to Brussels
- Frankfurt am Main to Brussels
- Innsbruck to Brussels
- Leipzig to Brussels
- Lille to Brussels
- Lisbon to Brussels
- Lyon to Brussels
- Maastricht to Brussels
- Madrid to Brussels
- Milan to Brussels
- Münster to Brussels
- Newcastle upon Tyne to Brussels
- Sofia to Brussels
- Utrecht to Brussels
- Zurich to Brussels
