What is the best way to travel from Prague to Brussels?
Looking for a trip? Compare all the available Buses and Flights for the journey to Brussels from Prague. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Prague?
You can get to Brussels with just $68 by taking a Flight from Smartwings, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/23/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/23/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/23/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 7:20:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 15h 5m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/23/2025 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 9:27:00 AM. 50 Economy ticket for $637 per person are available. Travel duration is 15h 27m
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Buzz14h 10m05:55 AMPrague AirportPrague Airport - T1/28:05 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 5:55:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/23/2025 8:05:00 PM. 50 Economy ticket for $297 per person are available. Travel duration is 14h 10m
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Jet2.com29h 35m012:45 PMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 12:45:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $315 per person are available. Travel duration is 29h 35m
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Ryanair30h 45m011:35 AMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 11:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $336 per person are available. Travel duration is 30h 45m
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EasyJet Airline20h 40m09:40 PMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:40:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $359 per person are available. Travel duration is 20h 40m
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Smartwings35h 40m06:40 AMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 6:40:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $441 per person are available. Travel duration is 35h 40m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/24/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 50m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/24/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 7:20:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 15h 5m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/24/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/24/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/24/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/24/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 55m
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FlixBus20h 0m011:20 AMPrague AirportPrague Airport - T1/27:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/24/2025 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 7:20:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 0m
Cheapest Buses Wednesday
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/25/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/25/2025 6:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/25/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/25/2025 6:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/25/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/26/2025 7:20:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 15h 5m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/25/2025 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/26/2025 9:27:00 AM. 50 Economy ticket for $336 per person are available. Travel duration is 15h 27m
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Vueling Airlines30h 30m03:50 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 3:50:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $265 per person are available. Travel duration is 30h 30m
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Air Bagan29h 15m05:05 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 5:05:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 29h 15m
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Smartwings34h 45m011:35 AMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 11:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $276 per person are available. Travel duration is 34h 45m
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Transavia France25h 40m08:40 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Transavia France goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 8:40:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $400 per person are available. Travel duration is 25h 40m
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Brussels Airlines27h 35m06:45 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 6:45:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $463 per person are available. Travel duration is 27h 35m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/26/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/26/2025 6:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/26/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/26/2025 6:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 13h 55m
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/26/2025 11:05:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 12:25:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/26/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/27/2025 7:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 5m
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FlixBus16h 50m08:50 AMPrague AirportPrague Airport - T1/21:40 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 8:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/27/2025 1:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 16h 50m
Cheapest Buses Friday
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Smartwings1h 30m06:40 AMPrague AirportPrague Airport - T1/28:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:40:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/27/2025 8:10:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 1h 30m
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Ryanair19h 20m03:45 PMPrague AirportPrague Airport - T1/211:05 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 3:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/28/2025 11:05:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 19h 20m
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Buzz1h 30m02:35 PMPrague AirportPrague Airport - T1/24:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 2:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/27/2025 4:05:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 1h 30m
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LOT Polish Airlines / Polskie Linie Lotnicze15h 35m06:00 PMPrague AirportPrague Airport - T1/29:35 AMBrussels AirportBrussels Airport0EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/28/2025 9:35:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 15h 35m
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Ryanair11h 5m010:00 PMPrague AirportPrague Airport - T1/29:05 AMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 10:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/28/2025 9:05:00 AM. 50 Economy ticket for $165 per person are available. Travel duration is 11h 5m
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Skyscanner8h 35m01:45 PMPrague AirportPrague Airport - T1/210:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 1:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/27/2025 10:20:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 8h 35m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/27/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/27/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 55m
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FlixBus13h 20m010:35 AMPragueÚAN Florenc11:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/27/2025 10:35:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 11:55:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 20m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/27/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/28/2025 7:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 5m
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FlixBus16h 25m09:15 AMPrague AirportPrague Airport - T1/21:40 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 9:15:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/28/2025 1:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 16h 25m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/28/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/28/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/28/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/28/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 55m
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FlixBus13h 20m010:55 AMPragueÚAN Florenc12:15 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/28/2025 10:55:00 AM to North Station, Brussels (Belgium) arriving at 12/29/2025 12:15:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 13h 20m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/28/2025 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/29/2025 9:27:00 AM. 50 Economy ticket for $351 per person are available. Travel duration is 15h 27m
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Ryanair10h 20m09:50 PMPrague AirportPrague Airport - T1/28:10 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 9:50:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/29/2025 8:10:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 20m
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Ryanair16h 35m03:35 PMPrague AirportPrague Airport - T1/28:10 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 3:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/29/2025 8:10:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 16h 35m
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LOT Polish Airlines / Polskie Linie Lotnicze14h 0m07:35 PMPrague AirportPrague Airport - T1/29:35 AMBrussels AirportBrussels Airport0EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 7:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/29/2025 9:35:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 14h 0m
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KLM - Royal Dutch Airlines4h 10m06:00 AMPrague AirportPrague Airport - T1/210:10 AMBrussels AirportBrussels Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/28/2025 10:10:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 4h 10m
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Buzz4h 10m06:20 PMPrague AirportPrague Airport - T1/210:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:20:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/28/2025 10:30:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 4h 10m
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Buzz4h 5m07:40 AMPrague AirportPrague Airport - T1/211:45 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 7:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/28/2025 11:45:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 4h 5m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus13h 20m010:55 AMPragueÚAN Florenc12:15 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/29/2025 10:55:00 AM to North Station, Brussels (Belgium) arriving at 12/30/2025 12:15:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 20m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/29/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/29/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 14h 15m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/29/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/29/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 55m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/29/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/30/2025 7:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 5m
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FlixBus15h 25m08:50 AMPrague AirportPrague Airport - T1/212:15 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/29/2025 8:50:00 AM to North Station, Brussels (Belgium) arriving at 12/30/2025 12:15:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 25m
Cheapest Buses Monday
What are the fastest trips from Prague to Brussels?
You can get to Brussels from Prague in just 1h 30m with a Flight from Buzz. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/23/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/23/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/23/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/23/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 7:20:00 AM. 50 Economy ticket for $98 per person are available. Travel duration is 15h 5m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/23/2025 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/24/2025 9:27:00 AM. 50 Economy ticket for $637 per person are available. Travel duration is 15h 27m
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Buzz14h 10m05:55 AMPrague AirportPrague Airport - T1/28:05 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 5:55:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/23/2025 8:05:00 PM. 50 Economy ticket for $297 per person are available. Travel duration is 14h 10m
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EasyJet Airline20h 40m09:40 PMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 9:40:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $359 per person are available. Travel duration is 20h 40m
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Jet2.com29h 35m012:45 PMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 12:45:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $315 per person are available. Travel duration is 29h 35m
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Ryanair30h 45m011:35 AMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 11:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $336 per person are available. Travel duration is 30h 45m
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Smartwings35h 40m06:40 AMPrague AirportPrague Airport - T1/26:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/23/2025 6:40:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/24/2025 6:20:00 PM. 50 Economy ticket for $441 per person are available. Travel duration is 35h 40m
Fastest Buses Tuesday
Fastest Flights Tuesday
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/24/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/24/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/24/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/24/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 15m
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FlixBus14h 50m011:05 PMPragueÚAN Florenc1:55 PMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/24/2025 11:05:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 1:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 50m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/24/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 7:20:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 15h 5m
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FlixBus20h 0m011:20 AMPrague AirportPrague Airport - T1/27:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/24/2025 11:20:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/25/2025 7:20:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 20h 0m
Fastest Buses Wednesday
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/25/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/25/2025 6:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/25/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/25/2025 6:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/25/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/26/2025 7:20:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 15h 5m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/25/2025 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/26/2025 9:27:00 AM. 50 Economy ticket for $336 per person are available. Travel duration is 15h 27m
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Transavia France25h 40m08:40 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Transavia France goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 8:40:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $400 per person are available. Travel duration is 25h 40m
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Brussels Airlines27h 35m06:45 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 6:45:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $463 per person are available. Travel duration is 27h 35m
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Air Bagan29h 15m05:05 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 5:05:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 29h 15m
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Vueling Airlines30h 30m03:50 PMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 3:50:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $265 per person are available. Travel duration is 30h 30m
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Smartwings34h 45m011:35 AMPrague AirportPrague Airport - T1/210:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/25/2025 11:35:00 AM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 12/26/2025 10:20:00 PM. 50 Economy ticket for $276 per person are available. Travel duration is 34h 45m
Fastest Buses Thursday
Fastest Flights Thursday
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FlixBus13h 20m011:05 AMPragueÚAN Florenc12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/26/2025 11:05:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 12:25:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/26/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/26/2025 6:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/26/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/26/2025 6:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/26/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/27/2025 7:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 5m
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FlixBus16h 50m08:50 AMPrague AirportPrague Airport - T1/21:40 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/26/2025 8:50:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/27/2025 1:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 16h 50m
Fastest Buses Friday
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Buzz1h 30m02:35 PMPrague AirportPrague Airport - T1/24:05 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 2:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/27/2025 4:05:00 PM. 50 Economy ticket for $138 per person are available. Travel duration is 1h 30m
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Smartwings1h 30m06:40 AMPrague AirportPrague Airport - T1/28:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:40:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/27/2025 8:10:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 1h 30m
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KLM - Royal Dutch Airlines4h 10m06:00 AMPrague AirportPrague Airport - T1/210:10 AMBrussels AirportBrussels Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/27/2025 10:10:00 AM. 50 Economy ticket for $237 per person are available. Travel duration is 4h 10m
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Skyscanner8h 35m01:45 PMPrague AirportPrague Airport - T1/210:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 1:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/27/2025 10:20:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 8h 35m
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Ryanair11h 5m010:00 PMPrague AirportPrague Airport - T1/29:05 AMBrussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 10:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/28/2025 9:05:00 AM. 50 Economy ticket for $165 per person are available. Travel duration is 11h 5m
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KLM Cityhopper13h 55m08:15 PMPrague AirportPrague Airport - T1/210:10 AMBrussels AirportBrussels Airport0EconomyA Flight from KLM Cityhopper goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 8:15:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/28/2025 10:10:00 AM. 50 Economy ticket for $258 per person are available. Travel duration is 13h 55m
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FlixBus13h 20m010:35 AMPragueÚAN Florenc11:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/27/2025 10:35:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 11:55:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/27/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/27/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/27/2025 6:05:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/27/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/28/2025 7:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 5m
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FlixBus16h 25m09:15 AMPrague AirportPrague Airport - T1/21:40 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/27/2025 9:15:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 12/28/2025 1:40:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 16h 25m
Fastest Flights Saturday
Fastest Buses Saturday
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Smartwings1h 30m05:15 PMPrague AirportPrague Airport - T1/26:45 PMBrussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 5:15:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/28/2025 6:45:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 1h 30m
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Buzz4h 5m07:40 AMPrague AirportPrague Airport - T1/211:45 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 7:40:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/28/2025 11:45:00 AM. 50 Economy ticket for $182 per person are available. Travel duration is 4h 5m
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Buzz4h 10m06:20 PMPrague AirportPrague Airport - T1/210:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:20:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/28/2025 10:30:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 4h 10m
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KLM - Royal Dutch Airlines4h 10m06:00 AMPrague AirportPrague Airport - T1/210:10 AMBrussels AirportBrussels Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 6:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 12/28/2025 10:10:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 4h 10m
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Skyscanner5h 30m08:00 AMPrague AirportPrague Airport - T1/21:30 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 8:00:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/28/2025 1:30:00 PM. 50 Economy ticket for $206 per person are available. Travel duration is 5h 30m
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Ryanair10h 20m09:50 PMPrague AirportPrague Airport - T1/28:10 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/28/2025 9:50:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 12/29/2025 8:10:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 10h 20m
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FlixBus13h 20m010:55 AMPragueÚAN Florenc12:15 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/28/2025 10:55:00 AM to North Station, Brussels (Belgium) arriving at 12/29/2025 12:15:00 AM. 50 Economy ticket for $95 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/28/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/28/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/28/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/28/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 14h 15m
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European Sleeper15h 27m06:00 PMPragueWilsonova Bus Station9:27 AMBrusselsMidi Bus Station0EconomyA Bus from European Sleeper goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/28/2025 6:00:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/29/2025 9:27:00 AM. 50 Economy ticket for $351 per person are available. Travel duration is 15h 27m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus13h 20m010:55 AMPragueÚAN Florenc12:15 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/29/2025 10:55:00 AM to North Station, Brussels (Belgium) arriving at 12/30/2025 12:15:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 13h 20m
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FlixBus13h 55m04:10 AMPragueNa Knížecí Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 12/29/2025 4:10:00 AM to North Station, Brussels (Belgium) arriving at 12/29/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 13h 55m
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FlixBus14h 15m03:50 AMPragueWilsonova Bus Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Wilsonova Bus Station, Prague (Czech Republic) at 12/29/2025 3:50:00 AM to North Station, Brussels (Belgium) arriving at 12/29/2025 6:05:00 PM. 50 Economy ticket for $92 per person are available. Travel duration is 14h 15m
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FlixBus15h 5m04:15 PMPragueÚAN Florenc7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 12/29/2025 4:15:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 12/30/2025 7:20:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 5m
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FlixBus15h 25m08:50 AMPrague AirportPrague Airport - T1/212:15 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 12/29/2025 8:50:00 AM to North Station, Brussels (Belgium) arriving at 12/30/2025 12:15:00 AM. 50 Economy ticket for $92 per person are available. Travel duration is 15h 25m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Prague to Brussels
What are the most popular stations in Prague and Brussels?
In Prague, you will usually depart from Wilsonova Bus Station, ÚAN Florenc or Černý Most, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Prague? With 9 connections between 4 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Brussels, you can pay as low as $68 with a Flight from Smartwings.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Buzz: you will get to Brussels in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Brussels are FlixBus, Smartwings and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Saint-Gilles, and look at flights from Prague Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Brussels?
The most popular companies between Prague and Brussels, are FlixBus, Smartwings and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and European Sleeper
Airlines: Smartwings, Ryanair, Buzz and 14 more.
All you need to know when you travel from Prague to Brussels
Check all information on comfort and services on all modes of transports from Prague to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Brussels
How can I reach Brussels from Prague?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Brussels from Prague.
How far is Brussels from Prague?
The distance between Prague and Brussels is 446.6 miles.
What is the most ecofriendly mode of transport between Prague and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 122 kgs, and a flight 177 kgs.
What is the cheapest mode of transport from Prague to Brussels?
You can get to Brussels with just $68 by taking a Flight from Smartwings.
What is the fastest way to get from Prague to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 30m with a Flight from Buzz.
More routes to Prague and to Brussels
Looking for more options? Here you can see the most popular routes to Prague and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Belgrade to Prague
- Berlin to Prague
- Brno to Prague
- Budapest to Prague
- Česká Lípa to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Pelhřimov to Prague
- Třebíč to Prague
- Vienna to Prague
- Vilnius to Prague
- Zurich to Prague
- Trips to Brussels
- Angers to Brussels
- Basel to Brussels
- Berlin to Brussels
- Bremen to Brussels
- Bruges (BE) to Brussels
- Carcassonne to Brussels
- Dusseldorf to Brussels
- Frankfurt am Main to Brussels
- Glasgow to Brussels
- Hamburg to Brussels
- Hendaye to Brussels
- Innsbruck to Brussels
- Le Mans to Brussels
- Leeds to Brussels
- Lugano to Brussels
- Madrid to Brussels
- Milan to Brussels
- Nottingham to Brussels
- Nuremberg to Brussels
- Porto to Brussels
- Rotterdam to Brussels
- Salzburg to Brussels
- Sofia to Brussels
- Valencia to Brussels
