Compare all timetables for the bus from Siena to Milan
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 0m | 7:45 PM | Siena | Train Station | 12:45 AM | Milan | San Donato Bus Station | Economy | $22 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/6/2025 7:45:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/7/2025 12:45:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 0m
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| FlixBus | 5h 34m | 7:45 PM | Siena | Train Station | 1:19 AM | Milan | Lampugnano Bus Station | Economy | $22 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/6/2025 7:45:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 1:19:00 AM. 50 Economy ticket for $22 per person are available. Travel duration is 5h 34m
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| FlixBus | 7h 20m | 2:25 PM | Siena | Train Station | 9:45 PM | Milan | Lampugnano Bus Station | Economy | $23 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/6/2025 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/6/2025 9:45:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 7h 20m
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| FlixBus | 7h 35m | 11:20 AM | Siena | Train Station | 6:55 PM | Milan | Lampugnano Bus Station | Economy | $24 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/6/2025 11:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/6/2025 6:55:00 PM. 50 Economy ticket for $24 per person are available. Travel duration is 7h 35m
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| FlixBus | 4h 50m | 4:05 PM | Siena | Train Station | 8:55 PM | Milan | San Donato Bus Station | Economy | $26 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/6/2025 4:05:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/6/2025 8:55:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 4h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 15m | 9:20 AM | Siena | Train Station | 2:35 PM | Milan | San Donato Bus Station | Economy | $14 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 9:20:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/7/2025 2:35:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 5h 15m
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| FlixBus | 6h 0m | 9:20 AM | Siena | Train Station | 3:20 PM | Milan | Lampugnano Bus Station | Economy | $14 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 9:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 3:20:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 6h 0m
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| FlixBus | 7h 20m | 2:25 PM | Siena | Train Station | 9:45 PM | Milan | Lampugnano Bus Station | Economy | $14 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/7/2025 2:25:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/7/2025 9:45:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 7h 20m
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| Itabus | 7h 40m | 4:55 PM | Siena | Central Bus Station | 12:35 AM | Milan | Lampugnano Bus Station | Economy | $15 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 12/7/2025 4:55:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 12:35:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 7h 40m
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| Itabus | 6h 30m | 1:05 AM | Siena | Train Station | 7:35 AM | Milan | San Donato Bus Station | Premium Economy | $17 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 12/7/2025 1:05:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/7/2025 7:35:00 AM. 50 Premium Economy ticket for $17 per person are available. Travel duration is 6h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 4h 50m | 6:40 AM | Siena | Train Station | 11:30 AM | Milan | San Donato Bus Station | Economy | $17 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/8/2025 6:40:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/8/2025 11:30:00 AM. 50 Economy ticket for $17 per person are available. Travel duration is 4h 50m
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| FlixBus | 5h 45m | 6:10 AM | Siena | Train Station | 11:55 AM | Milan | Lampugnano Bus Station | Economy | $23 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/8/2025 6:10:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 11:55:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 5h 45m
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| FlixBus | 7h 35m | 11:20 AM | Siena | Train Station | 6:55 PM | Milan | Lampugnano Bus Station | Economy | $36 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/8/2025 11:20:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 6:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 7h 35m
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| FlixBus | 5h 50m | 7:50 AM | Siena | Train Station | 1:40 PM | Milan | Lampugnano Bus Station | Economy | $37 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/8/2025 7:50:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/8/2025 1:40:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 5h 50m
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| FlixBus | 4h 30m | 12:45 AM | Siena | Train Station | 5:15 AM | Milan | San Donato Bus Station | Economy | $40 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/8/2025 12:45:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/8/2025 5:15:00 AM. 50 Economy ticket for $40 per person are available. Travel duration is 4h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 4h 30m | 12:45 AM | Siena | Train Station | 5:15 AM | Milan | San Donato Bus Station | Economy | $28 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/9/2025 12:45:00 AM to San Donato Bus Station, Milan (Italy) arriving at 12/9/2025 5:15:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 4h 30m
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| FlixBus | 5h 10m | 12:45 AM | Siena | Train Station | 5:55 AM | Milan | Lampugnano Bus Station | Economy | $28 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/9/2025 12:45:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/9/2025 5:55:00 AM. 50 Economy ticket for $28 per person are available. Travel duration is 5h 10m
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| FlixBus | 6h 35m | 3:05 PM | Siena | Train Station | 9:40 PM | Milan | Lampugnano Bus Station | Economy | $28 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 12/9/2025 3:05:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/9/2025 9:40:00 PM. 50 Economy ticket for $28 per person are available. Travel duration is 6h 35m
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| Itabus | 5h 50m | 1:05 AM | Siena | Train Station | 6:55 AM | Milan | Lampugnano Bus Station | Economy | $30 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 12/9/2025 1:05:00 AM to Lampugnano Bus Station, Milan (Italy) arriving at 12/9/2025 6:55:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 5h 50m
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| Itabus | 6h 0m | 6:35 PM | Siena | Train Station | 12:35 AM | Milan | Lampugnano Bus Station | Economy | $30 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 12/9/2025 6:35:00 PM to Lampugnano Bus Station, Milan (Italy) arriving at 12/10/2025 12:35:00 AM. 50 Economy ticket for $30 per person are available. Travel duration is 6h 0m
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FlixBus5h 44m06:05 PMSienaTrain Station7:00 PMFlorenceVilla Costanza Bus Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 12/10/2025 6:05:00 PM to Villa Costanza Bus Station, Florence (Italy) arriving at 12/10/2025 7:00:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 0h 55m
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Distribusion4h 14m07:35 PMFlorenceVilla Costanza Bus Station11:49 PMMilanSan Donato Bus Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 12/10/2025 7:35:00 PM to San Donato Bus Station, Milan (Italy) arriving at 12/10/2025 11:49:00 PM. 50 Premium Economy ticket for $12 per person are available. Travel duration is 4h 14m
Waiting Time 0h 35m -
Best Price Offer: The price for the cheapest bus from Siena to Milan is $10 on 12/13/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Siena and Milan
Facts about the bus from Siena to Milan
Compare all providers like Itabus and FlixBus that travel 38 times every day by bus from Siena to Milan in one click! Book your bus ticket from Siena to Milan starting from $10!
| Cheapest Bus | $10 |
| Fastest Bus | 4h 30m |
| Earliest Bus | 12:45 AM |
| Latest Bus | 9:55 PM |
| Daily Bus Routes | 38 Ø |
| Distance | 182.3 miles |
| Bus Companies | Itabus and FlixBus |
Cheapest bus connections from Siena to Milan
Every day, 38 buses from 2 bus companies leave Siena for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.
The cheapest time to travel from Siena to Milan
How to save money travelling from Siena to Milan
Book the ticket from Siena to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siena to Milan are also emptier.Beloved bus companies from Siena to Milan
FlixBus from Siena to Milan
Here you will find the key facts about the FlixBus bus route Siena to Milan:
| Cheapest Price | $14 |
| Fastest Bus | 4h 30m |
| Earliest Bus | 12:45 AM |
| Last Bus | 9:55 PM |
| Daily Connections | 16 Ø |
| Found on | 12/1/2025 |
Itabus from Siena to Milan
Here you will find the key facts about the Itabus bus route Siena to Milan:
| Cheapest Price | $15 |
| Fastest Bus | 5h 14m |
| Earliest Bus | 1:05 AM |
| Last Bus | 6:50 PM |
| Daily Connections | 43 Ø |
| Found on | 12/1/2025 |
All bus stations and stops in Siena and Milan
In the map below, you can see where to find all bus stations in Siena and Milan.
Compare the bus with other modes of transport
Service and Comfort on the bus from Siena to Milan
FAQs about the Siena to Milan bus
How much does a Siena Milan bus trip cost?
How much could I save by comparing buses from Siena to Milan?
On average, how many connections are available from Siena to Milan each day?
How long does a bus journey from Siena to Milan take?
What time is the first bus from Siena to Milan?
What time is the last bus from Siena to Milan?
Which bus companies operate the Siena Milan route?
Is there a direct bus between Siena and Milan?
What can I take with me on the Siena to Milan bus route?
What equipment is available for the Siena Milan bus route?
Available seat classes which are offered on the bus route Siena to Milan
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Siena and to Milan
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