Bus from Siena to Milan from $8

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Compare all timetables for the bus from Siena to Milan

Here is a selection of the cheapest bus trips from the schedule from Siena to Milan from various bus operators like Itabus or FlixBus for the next days.

today
$9
tomorrow
$18
Saturday
$8
Sunday
$21
Monday
$30
Tuesday
$21
Wednesday
$13

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 5h 45m 10:55 AM Siena Piazza Antonio Gramsci 4:40 PM Milan Lampugnano Bus Station  Economy $9
Itabus 7h 30m 1:55 PM Siena Central Bus Station 9:25 PM Milan Lampugnano Bus Station  Economy $13
FlixBus 5h 50m 6:10 AM Siena Train Station 12:00 PM Milan San Donato Bus Station  Economy $16
FlixBus 5h 15m 9:20 AM Siena Train Station 2:35 PM Milan San Donato Bus Station  Economy $16
FlixBus 6h 50m 6:10 AM Siena Train Station 1:00 PM Milan Lampugnano Bus Station  Economy $16

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 4h 50m 4:05 PM Siena Train Station 8:55 PM Milan San Donato Bus Station  Economy $18
FlixBus 4h 50m 6:40 AM Siena Train Station 11:30 AM Milan San Donato Bus Station  Economy $20
FlixBus 6h 10m 5:25 PM Siena Train Station 11:35 PM Milan Lampugnano Bus Station  Economy $20
Itabus 5h 45m 10:55 AM Siena Train Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $23
Itabus 7h 30m 1:55 PM Siena Train Station 9:25 PM Milan Lampugnano Bus Station  Premium Economy $60
  • Did you know that if you travel from Assago to Siena via Milan, you can save more than $-89? You will find the corresponding connections below.
    • 0h 25m
      0 mi
      8:30 PM
      Assago
      Milanofiori Forum
      8:55 PM
      Milan
      San Donato Bus Station
      181 mi
      Siena
      Economy
      $107

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 5h 45m 10:55 AM Siena Train Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $8
FlixBus 5h 10m 12:45 AM Siena Train Station 5:55 AM Milan Lampugnano Bus Station  Economy $9
FlixBus 6h 50m 6:10 AM Siena Train Station 1:00 PM Milan Lampugnano Bus Station  Economy $9
FlixBus 5h 55m 7:50 AM Siena Train Station 1:45 PM Milan Lampugnano Bus Station  Economy $9
Itabus 7h 30m 1:55 PM Siena Train Station 9:25 PM Milan Lampugnano Bus Station  Premium Economy $12

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 5h 45m 10:55 AM Siena Train Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $21
FlixBus 6h 10m 5:25 PM Siena Train Station 11:35 PM Milan Lampugnano Bus Station  Economy $25
FlixBus 4h 50m 6:40 AM Siena Train Station 11:30 AM Milan San Donato Bus Station  Economy $28
FlixBus 4h 50m 4:05 PM Siena Train Station 8:55 PM Milan San Donato Bus Station  Economy $28
Itabus 4h 55m 1:55 PM Siena Train Station 6:50 PM Milan San Donato Bus Station  Premium Economy $36
  • Did you know that if you travel from Assago to Siena via Milan, you can save more than $-40? You will find the corresponding connections below.
    • 0h 25m
      0 mi
      8:30 PM
      Assago
      Milanofiori Forum
      8:55 PM
      Milan
      San Donato Bus Station
      181 mi
      Siena
      Economy
      $61

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 4h 55m 1:55 PM Siena Train Station 6:50 PM Milan San Donato Bus Station  Premium Economy $30
Itabus 5h 45m 10:55 AM Siena Piazza Antonio Gramsci 4:40 PM Milan Lampugnano Bus Station  Economy $52
Itabus 7h 30m 1:55 PM Siena Train Station 9:25 PM Milan Lampugnano Bus Station  Premium Economy $57
Itabus 5h 50m 1:05 AM Siena Train Station 6:55 AM Milan Lampugnano Bus Station  Premium Economy $65
Itabus 6h 30m 1:05 AM Siena Train Station 7:35 AM Milan San Donato Bus Station  Premium Economy $118
  • Did you know that if you travel from Siena to Milan via Florence, you can save more than $9? You can find the corresponding connections below.
    • MarinoBus
      5h 30m
      0
      4:50 PM
      Siena
      Train Station
      5:50 PM
      Florence
      Villa Costanza Bus Station
      0
      MarinoBus
      Economy
      $10
      • Waiting Time 0h 20m
    • FlixBus
      4h 10m
      0
      6:10 PM
      Florence
      Villa Costanza Bus Station
      10:20 PM
      Milan
      San Donato Bus Station
      0
      FlixBus
      Economy
      $11
    Travel time is 0h 35m longer, but you will save $9

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 5h 45m 10:55 AM Siena Train Station 4:40 PM Milan Lampugnano Bus Station  Premium Economy $21
Itabus 7h 30m 1:55 PM Siena Train Station 9:25 PM Milan Lampugnano Bus Station  Premium Economy $23
Itabus 4h 55m 1:55 PM Siena Train Station 6:50 PM Milan San Donato Bus Station  Premium Economy $24
  • Did you know that if you travel from Assago to Siena via Milan, you can save more than $-34? You will find the corresponding connections below.
    • 0h 25m
      0 mi
      8:30 PM
      Assago
      Milanofiori Forum
      8:55 PM
      Milan
      San Donato Bus Station
      181 mi
      Siena
      Economy
      $55

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 5h 45m 10:55 AM Siena Piazza Antonio Gramsci 4:40 PM Milan Lampugnano Bus Station  Economy $13
Itabus 4h 55m 1:55 PM Siena Train Station 6:50 PM Milan San Donato Bus Station  Premium Economy $24
FlixBus 5h 40m 12:15 PM Siena Train Station 5:55 PM Milan Lampugnano Bus Station  Economy $27
FlixBus 5h 19m 6:40 PM Siena Train Station 11:59 PM Milan Lampugnano Bus Station  Economy $27
FlixBus 4h 30m 12:45 AM Siena Train Station 5:15 AM Milan San Donato Bus Station  Economy $29

Best Price Offer: The price for the cheapest bus from Siena to Milan is $8 on 8/8/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Siena and Milan

See here how frequent the connections between Siena and Milan are, during different times and days of the week.
Thursday is the busiest day, with more than 40 daily buses from Siena to Milan. Tuesday has instead the fewest connections, with only 8 daily coaches between Siena and Milan.
The busiest time of the day is the Afternoon, with 68 buses from Siena to Milan, while Evening sees the fewest connections between Siena and Milan, with 5 offers.

Facts about the bus from Siena to Milan

Compare all providers like Itabus and FlixBus that travel 24 times every day by bus from Siena to Milan in one click! Book your bus ticket from Siena to Milan starting from $8!

Cheapest Bus $8
Fastest Bus 4h 30m
Earliest Bus 12:45 AM
Latest Bus 6:40 PM
Daily Bus Routes 24 Ø
Distance 182.3 miles
Bus Companies Itabus and FlixBus

Cheapest bus connections from Siena to Milan

Every day, 24 buses from 2 bus companies leave Siena for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/06/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 08/02
Monday 08/03
Tuesday 08/04
Wednesday 08/05
Thursday 08/06
$44
Friday 08/07
$151
Saturday 08/08
$8
Sunday 08/09
$24
Monday 08/10
$23
Tuesday 08/11
$18
Wednesday 08/12
$13
Thursday 08/13
$17
Friday 08/14
Saturday 08/15
$24
Sunday 08/16
$16
Monday 08/17
$53
Tuesday 08/18
$20
Wednesday 08/19
$23
Thursday 08/20
$12
Friday 08/21
$9
Saturday 08/22
$12
Sunday 08/23
Monday 08/24
$51
Tuesday 08/25
$20
Wednesday 08/26
$15
Thursday 08/27
$8
Friday 08/28
$29
Saturday 08/29

The cheapest time to travel from Siena to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Siena to Milan, for the next 30 days.
With a price starting from $8, Saturday is the cheapest day for a bus from Siena to Milan. Monday instead is the most expensive day with prices starting from $23.
Morning is the cheapest day time for bus tickets from Siena to Milan, with $8. Afternoon is the most expensive time of the day with prices starting from $12.

How to save money travelling from Siena to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Siena to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Siena to Milan are also emptier.

All bus stations and stops in Siena and Milan

In the map below, you can see where to find all bus stations in Siena and Milan.

Service and Comfort on the bus from Siena to Milan

Want to know which seat classes are available on the buses from Siena to Milan? Or which bus companies serve the route Siena to Milan? Below you will find answers to your questions.

FAQs about the Siena to Milan bus

How much does a Siena Milan bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $8 and takes 5h 45m to reach Milan. Compare offers to save money!

How much could I save by comparing buses from Siena to Milan?

This route is offered by 2 companies with a range of ticket prices between $8 and $118. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Milan.

On average, how many connections are available from Siena to Milan each day?

Every day, the Siena to Milan bus route is served by approximately 24 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Siena to Milan take?

The fastest bus from Siena to Milan is offered by FlixBus and takes 4h 30m. Bus tickets for this connection cost $21. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Siena to Milan?

The earliest bus arriving in Milan from Siena starts at 12:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Siena to Milan?

The latest bus trip departing from Siena for Milan starts at 6:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Siena Milan route?

When traveling by bus from Siena to Milan, passengers can travel with Itabus and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Siena and Milan?

You can check all the direct connections between Siena and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus and FlixBus.

What can I take with me on the Siena to Milan bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Siena Milan bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Siena Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siena to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Siena to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 24 daily trips between Siena and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Siena to Milan?

Prices and availability for 24 trips between Siena and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Siena to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Siena and to Milan

Here’s an overview of the most popular bus routes to Siena and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Sesto San Giovanni - Siena Buses Sesto San Giovanni - Siena
Buses from Lauria to Siena Buses from Lauria to Siena
Buses Poggibonsi to Siena Buses Poggibonsi to Siena
Bus Civitavecchia - Siena Bus Civitavecchia - Siena
Bus to Milan from Oslo Bus to Milan from Oslo
From Rotterdam to Milan bus From Rotterdam to Milan bus
Bus to Milan from Krakow Bus to Milan from Krakow
Bus Brescia to Milan Bus Brescia to Milan
Popular Airport Shuttles to Siena and to Milan
CheckMyBus › Buses in Italy › Bus to Siena › Bus to Milan

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