Bus Caserta to Siena - Compare all Companies

Compare all timetables for the bus from Caserta to Siena

Here is a selection of the cheapest bus trips from the schedule from Caserta to Siena from various bus operators like FlixBus or Itabus for the next days.

today

$49

tomorrow

$48

Thursday

Friday

$36

Saturday

Sunday

$28

Monday

$37

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 30m	4:40 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	12:10 PM	Siena	Train Station	Economy	$49	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/23/2025 4:40:00 AM to Train Station, Siena (Italy) arriving at 12/23/2025 12:10:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 7h 30m
FlixBus	6h 55m	5:15 AM	Caserta	Train Station	12:10 PM	Siena	Train Station	Economy	$49	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/23/2025 5:15:00 AM to Train Station, Siena (Italy) arriving at 12/23/2025 12:10:00 PM. 50 Economy ticket for $49 per person are available. Travel duration is 6h 55m
FlixBus	5h 25m	8:55 AM	Caserta	Train Station	2:20 PM	Siena	Train Station	Economy	$57	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/23/2025 8:55:00 AM to Train Station, Siena (Italy) arriving at 12/23/2025 2:20:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 5h 25m
FlixBus	5h 25m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	3:00 PM	Siena	Train Station	Economy	$67	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/23/2025 9:35:00 AM to Train Station, Siena (Italy) arriving at 12/23/2025 3:00:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 5h 25m
FlixBus	5h 15m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	2:50 PM	Siena	Bus Stop	Economy	$67	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/23/2025 9:35:00 AM to Bus Stop, Siena (Italy) arriving at 12/23/2025 2:50:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 5h 15m

Did you know that if you travel from Caserta to Siena via Rome, you can save more than $21? You can find the corresponding connections below.
- FlixBus
  
  5h 54m
  
  0
  
  4:45 PM
  
  Caserta
  Caserta Nord Nazionale Appia Bus Stop
  
  7:00 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $15
  
  A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/24/2025 4:45:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/24/2025 7:00:00 PM. 50 Economy ticket for $15 per person are available. Travel duration is 2h 15m
- FlixBus
  
  2h 39m
  
  0
  
  8:00 PM
  
  Rome
  Tiburtina Bus Station
  
  10:39 PM
  
  Siena
  Bus Stop
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/24/2025 8:00:00 PM to Bus Stop, Siena (Italy) arriving at 12/24/2025 10:39:00 PM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 39m
Travel time is 0h 39m longer, but you will save $21

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 25m	8:55 AM	Caserta	Train Station	2:20 PM	Siena	Train Station	Economy	$48	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/24/2025 8:55:00 AM to Train Station, Siena (Italy) arriving at 12/24/2025 2:20:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 25m
FlixBus	5h 15m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	2:50 PM	Siena	Bus Stop	Economy	$64	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/24/2025 9:35:00 AM to Bus Stop, Siena (Italy) arriving at 12/24/2025 2:50:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 5h 15m
FlixBus	5h 25m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	3:00 PM	Siena	Train Station	Economy	$64	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/24/2025 9:35:00 AM to Train Station, Siena (Italy) arriving at 12/24/2025 3:00:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 5h 25m

Did you know that if you travel from Caserta to Siena via Rome, you can save more than $25? You can find the corresponding connections below.
- FlixBus
  
  5h 25m
  
  0
  
  8:55 AM
  
  Caserta
  Train Station
  
  11:15 AM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/25/2025 8:55:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/25/2025 11:15:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 20m
- FlixBus
  
  2h 55m
  
  0
  
  11:25 AM
  
  Rome
  Tiburtina Bus Station
  
  2:20 PM
  
  Siena
  Train Station
  
  0
  
  Economy
  
  $10
  
  A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 12/25/2025 11:25:00 AM to Train Station, Siena (Italy) arriving at 12/25/2025 2:20:00 PM. 50 Economy ticket for $10 per person are available. Travel duration is 2h 55m
Travel time is 0h 10m longer, but you will save $25

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 25m	8:55 AM	Caserta	Train Station	2:20 PM	Siena	Train Station	Economy	$36	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/26/2025 8:55:00 AM to Train Station, Siena (Italy) arriving at 12/26/2025 2:20:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 5h 25m
FlixBus	6h 55m	5:15 AM	Caserta	Train Station	12:10 PM	Siena	Train Station	Economy	$56	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/26/2025 5:15:00 AM to Train Station, Siena (Italy) arriving at 12/26/2025 12:10:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 6h 55m
FlixBus	5h 15m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	2:50 PM	Siena	Bus Stop	Economy	$67	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/26/2025 9:35:00 AM to Bus Stop, Siena (Italy) arriving at 12/26/2025 2:50:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 5h 15m
FlixBus	5h 25m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	3:00 PM	Siena	Train Station	Economy	$67	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/26/2025 9:35:00 AM to Train Station, Siena (Italy) arriving at 12/26/2025 3:00:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 5h 25m

Did you know that if you travel from Caserta to Siena via Rome, you can save more than $14? You can find the corresponding connections below.
- Distribusion
  
  5h 49m
  
  0
  
  7:15 PM
  
  Caserta
  Train Station
  
  9:35 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  $9
  
  A Bus from Distribusion goes from Train Station, Caserta (Italy) at 12/27/2025 7:15:00 PM to Tiburtina Bus Station, Rome (Italy) arriving at 12/27/2025 9:35:00 PM. 50 Premium Economy ticket for $9 per person are available. Travel duration is 2h 20m
- Tictactrip
  
  2h 49m
  
  0
  
  10:15 PM
  
  Rome
  Tiburtina Train Station
  
  1:04 AM
  
  Siena
  Central Bus Station
  
  0
  
  Economy
  
  $13
  
  A Bus from Tictactrip goes from Tiburtina Train Station, Rome (Italy) at 12/27/2025 10:15:00 PM to Central Bus Station, Siena (Italy) arriving at 12/28/2025 1:04:00 AM. 50 Economy ticket for $13 per person are available. Travel duration is 2h 49m
Travel time is 0h 34m longer, but you will save $14

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	5h 20m	11:30 AM	Caserta	Train Station	4:50 PM	Siena	Train Station	Premium Economy	$28	A Bus from Itabus goes from Train Station, Caserta (Italy) at 12/28/2025 11:30:00 AM to Train Station, Siena (Italy) arriving at 12/28/2025 4:50:00 PM. 50 Premium Economy ticket for $28 per person are available. Travel duration is 5h 20m
Itabus	7h 34m	8:31 AM	Caserta	Train Station	4:05 PM	Siena	Train Station	Premium Economy	$32	A Bus from Itabus goes from Train Station, Caserta (Italy) at 12/28/2025 8:31:00 AM to Train Station, Siena (Italy) arriving at 12/28/2025 4:05:00 PM. 50 Premium Economy ticket for $32 per person are available. Travel duration is 7h 34m
Itabus	7h 59m	8:06 AM	Caserta	Train Station	4:05 PM	Siena	Train Station	Premium Economy	$35	A Bus from Itabus goes from Train Station, Caserta (Italy) at 12/28/2025 8:06:00 AM to Train Station, Siena (Italy) arriving at 12/28/2025 4:05:00 PM. 50 Premium Economy ticket for $35 per person are available. Travel duration is 7h 59m
FlixBus	5h 25m	8:55 AM	Caserta	Train Station	2:20 PM	Siena	Train Station	Economy	$37	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/28/2025 8:55:00 AM to Train Station, Siena (Italy) arriving at 12/28/2025 2:20:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 5h 25m
FlixBus	6h 55m	5:15 AM	Caserta	Train Station	12:10 PM	Siena	Train Station	Economy	$50	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/28/2025 5:15:00 AM to Train Station, Siena (Italy) arriving at 12/28/2025 12:10:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 6h 55m

Did you know that if you travel from Caserta to Siena via Rome, you can save more than $7? You can find the corresponding connections below.
- Bookaway
  
  5h 20m
  
  0
  
  11:30 AM
  
  Caserta
  Central Bus Station
  
  1:50 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Basic
  
  $11
  
  A Bus from Bookaway goes from Central Bus Station, Caserta (Italy) at 12/29/2025 11:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 1:50:00 PM. 50 Basic ticket for $11 per person are available. Travel duration is 2h 20m
- Distribusion
  
  2h 50m
  
  0
  
  2:00 PM
  
  Rome
  Tiburtina Bus Station
  
  4:50 PM
  
  Siena
  Train Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 2:00:00 PM to Train Station, Siena (Italy) arriving at 12/29/2025 4:50:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 2h 50m
Travel time is the same as the direct connection, but you will save $7

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	5h 25m	8:55 AM	Caserta	Train Station	2:20 PM	Siena	Train Station	Economy	$37	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/29/2025 8:55:00 AM to Train Station, Siena (Italy) arriving at 12/29/2025 2:20:00 PM. 50 Economy ticket for $37 per person are available. Travel duration is 5h 25m
FlixBus	6h 55m	5:15 AM	Caserta	Train Station	12:10 PM	Siena	Train Station	Economy	$52	A Bus from FlixBus goes from Train Station, Caserta (Italy) at 12/29/2025 5:15:00 AM to Train Station, Siena (Italy) arriving at 12/29/2025 12:10:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 6h 55m
FlixBus	5h 25m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	3:00 PM	Siena	Train Station	Economy	$60	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/29/2025 9:35:00 AM to Train Station, Siena (Italy) arriving at 12/29/2025 3:00:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 5h 25m
FlixBus	5h 15m	9:35 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	2:50 PM	Siena	Bus Stop	Economy	$60	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/29/2025 9:35:00 AM to Bus Stop, Siena (Italy) arriving at 12/29/2025 2:50:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 5h 15m
FlixBus	6h 35m	4:40 AM	Caserta	Caserta Nord Nazionale Appia Bus Stop	11:15 AM	Siena	Train Station	Economy	$63	A Bus from FlixBus goes from Caserta Nord Nazionale Appia Bus Stop, Caserta (Italy) at 12/29/2025 4:40:00 AM to Train Station, Siena (Italy) arriving at 12/29/2025 11:15:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 6h 35m

Did you know that if you travel from Caserta to Siena via Rome, you can save more than $16? You can find the corresponding connections below.
- Bookaway
  
  5h 20m
  
  0
  
  11:30 AM
  
  Caserta
  Central Bus Station
  
  1:50 PM
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Basic
  
  $11
  
  A Bus from Bookaway goes from Central Bus Station, Caserta (Italy) at 12/29/2025 11:30:00 AM to Tiburtina Bus Station, Rome (Italy) arriving at 12/29/2025 1:50:00 PM. 50 Basic ticket for $11 per person are available. Travel duration is 2h 20m
- Distribusion
  
  2h 50m
  
  0
  
  2:00 PM
  
  Rome
  Tiburtina Bus Station
  
  4:50 PM
  
  Siena
  Train Station
  
  0
  
  Premium Economy
  
  $11
  
  A Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 12/29/2025 2:00:00 PM to Train Station, Siena (Italy) arriving at 12/29/2025 4:50:00 PM. 50 Premium Economy ticket for $11 per person are available. Travel duration is 2h 50m
Travel time is 0h 5m longer, but you will save $16

Best Price Offer: The price for the cheapest bus from Caserta to Siena is $28 on 12/28/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Caserta and Siena

See here how frequent the connections between Caserta and Siena are, during different times and days of the week.

Sunday is the busiest day, with more than 11 daily buses from Caserta to Siena. Wednesday has instead the fewest connections, with only 3 daily coaches between Caserta and Siena.

The busiest time of the day is the Morning, with 19 buses from Caserta to Siena, while Afternoon sees the fewest connections between Caserta and Siena, with 2 offers.

Facts about the bus from Caserta to Siena

Compare all providers like FlixBus and Itabus that travel 5 times every day by bus from Caserta to Siena in one click! Book your bus ticket from Caserta to Siena starting from $28!

Cheapest Bus	$28
Fastest Bus	5h 15m
Earliest Bus	4:40 AM
Latest Bus	9:35 AM
Daily Bus Routes	5 Ø
Distance	218.4 miles
Bus Companies	FlixBus and Itabus

Cheapest bus connections from Caserta to Siena

Every day, 5 buses from 2 bus companies leave Caserta for Siena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/23/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

Tuesday 12/23

$49

Wednesday 12/24

$48

Thursday 12/25

Friday 12/26

$36

Saturday 12/27

Sunday 12/28

$37

Monday 12/29

$37

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

Sunday 01/11

Monday 01/12

Tuesday 01/13

Wednesday 01/14

Thursday 01/15

Friday 01/16

Saturday 01/17

The cheapest time to travel from Caserta to Siena

See here on which day and which time of the day you can find the cheapest bus ticket from Caserta to Siena, for the next 30 days.

With a price starting from $28, Sunday is the cheapest day for a bus from Caserta to Siena. Tuesday instead is the most expensive day with prices starting from $49.

Morning is the cheapest day time for bus tickets from Caserta to Siena, with $28. Afternoon is the most expensive time of the day with prices starting from $87.

How to save money travelling from Caserta to Siena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Caserta to Siena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Caserta to Siena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Caserta to Siena are also emptier.

All bus stations and stops in Caserta and Siena

In the map below, you can see where to find all bus stations in Caserta and Siena.

Central Bus Station

Caserta Nord Nazionale Appia Bus Stop

Via Eleuterio Ruggiero

Bus Stop

Via Nazionale Appia 276

Piazza Antonio Gramsci

Central Bus Station

Bus Stop

Viale Pietro Toselli 9

Colonna San Marco

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Caserta to Siena? Compare all modes of transports from Caserta to Siena.

Service and Comfort on the bus from Caserta to Siena

Want to know which seat classes are available on the buses from Caserta to Siena? Or which bus companies serve the route Caserta to Siena? Below you will find answers to your questions.

FAQs about the Caserta to Siena bus

How much does a Caserta Siena bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $28 and takes 5h 20m to reach Siena. Compare offers to save money!

How much could I save by comparing buses from Caserta to Siena?

This route is offered by 2 companies with a range of ticket prices between $28 and $99. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Siena.

On average, how many connections are available from Caserta to Siena each day?

Every day, the Caserta to Siena bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Caserta to Siena take?

The fastest bus from Caserta to Siena is offered by FlixBus and takes 5h 15m. Bus tickets for this connection cost $67. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Caserta to Siena?

The earliest bus arriving in Siena from Caserta starts at 4:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Caserta to Siena?

The latest bus trip departing from Caserta for Siena starts at 9:35 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Caserta Siena route?

When traveling by bus from Caserta to Siena, passengers can travel with FlixBus and Itabus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Caserta and Siena?

You can check all the direct connections between Caserta and Siena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Itabus.

What can I take with me on the Caserta to Siena bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Caserta Siena bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Caserta Siena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Caserta to Siena on your planned travel date.

How does CheckMyBus find the best bus deals from Caserta to Siena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Caserta and Siena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Caserta to Siena?

Prices and availability for 5 trips between Caserta and Siena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Caserta to Siena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Caserta and to Siena

Here’s an overview of the most popular bus routes to Caserta and to Siena. Simply click on the connection of your choice, and you will find all the details about your bus route!